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Immature anophelines and their habitat characteristics in an urban setting of central Ethiopia


Abstract

Effective immature malaria vector control requires a comprehensive understanding of the relationship between Anopheles larvae and their habitats. In this study, we assessed habitat characteristics of Anopheles larvae and species composition of adult anophelines emerged from pupae. A repeated cross-sectional and longitudinal entomological study was conducted covering the catchment areas of Akaki, Serti and Gelan health centers, Akaki Kality Sub-City, central Ethiopia. Anopheles larvae were collected within a 100-meter radius of households of microscopically confirmed malaria case in any of the health centers between March 2024 and February 2025. Sampling was performed using the standard 350 ml dipper. Plastic pipettes and small white enamel pans were used for habitats of smaller size and shallow water bodies. Habitats were characterized during the survey. The collected anopheline larvae were separated from culicinae, counted, recorded, and transported, reared to adults and morphologically identified at the Center for Pathobiology Research of the Aklilu Lemma Health Research Institute. A total of 294 potential habitats of immature mosquitoes that belonged to 18 types were assessed. Drainage systems (29.6%; 87/294) were the most common habitat types. In total, 6977 larvae and 824 pupae were collected of which Anopheles larvae were 3064 (43.9%) with a median number of 68 ([IQR] 49–136). The Anopheles species included An. christyi (64.7%), An. gambiae s.l. (15.7%), An. cinereus (10.6%), An. demeilloni (2.8%), An. rhodesiensis (2.4%), An. garnhami (1.04%), An. wilsoni (0.47%), An. stephensi (0.28%), and An. nili (0.09%). Temporary habitats, stagnant water, sunlit, relatively large water volume, neutral to slightly alkaline water pH, and high total dissolved solids (TDS) contributed to favorable conditions for Anopheles larvae. The presence of multiple immature Anopheles species breeding in a variety of aquatic habitats indicates the potential for sustained malaria vector proliferation in Akaki Kality Sub-City. Specific physicochemical habitat characteristics influence the abundance of immature anophelines. The occurrence of multiple Anopheles species and the presence of favorable habitats indicate the need for implementing larval surveillance and targeted larval source management practices as part of integrated malaria vector control strategies.

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Abbreviations

AHRI:

Armauer Hansen Research Institute

GPS:

Global positioning system

IQR:

Inter quartile range

LST:

Land surface temperature

MODIS:

Moderate resolution imaging spectroradiometer

CHIRPS:

Climate hazards center infraRed precipitation with station

DEM:

Digital elevation model

MCE:

Multi-criteria evaluation

TDS:

Total dissolved solids

WHO:

World Health Organization

Acknowledgements

The authors would like to acknowledge the Armauer Hansen Research Institute (AHRI) Malaria and Neglected Tropical Disease Research Directorate for providing financial and material support necessary to conduct this study. We extend our sincere appreciation to the field and data teams at AHRI for their invaluable contributions. Our thanks also go to the Aklilu Lemma Institute of Health Research for their technical and facility support of rearing Anopheles mosquitoes. We are grateful to the Akaki, Gelan, and Serti health centers for their cooperation, and above all, to the community of Akaki Kality Sub-City, particularly residents of Woreda 1, 4, 8, 9, 12, and 13, including malaria patients and household owners, for their willingness to participate in this study.

Funding

This work was supported by the Armauer Hansen Research Institute Malaria and Neglected Tropical Diseases Research Directorate, Ethiopia, and Aklilu Lemma Institute of Health Research, Addis Ababa University, Addis Ababa, Ethiopia.

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Correspondence to
Aynye Negesse.

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The authors declare no competing interests.

Ethics approval and consent to participate

Ethical clearance was obtained from the Aklilu Lemma Institute of Health Research Institutional Research Ethics Review Committee (ALIPB-IRERC/118/2016/23). The Addis Ababa Health Bureau wrote a letter to Akaki Kality Sub-City to facilitate the study (A/A/9800/227). Akaki Kality Sub-City also wrote letters requesting support from the respective health centers participating in the study. Ethical approval was also obtained from the AHRI ALERT Ethics Review Committee (AAERC, P0-019-24). Informed consent was obtained from each house owner before sampling water sources around their houses and compounds.

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Negesse, A., Medhin, G., Aklilu, E. et al. Immature anophelines and their habitat characteristics in an urban setting of central Ethiopia.
Sci Rep (2026). https://doi.org/10.1038/s41598-026-63401-6

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  • DOI: https://doi.org/10.1038/s41598-026-63401-6

Keywords

  • Habitat characteristics
  • Immature anophelines
  • Urban setting
  • Central Ethiopia


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