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Household insecticide uses and flea infestation in plague-endemic regions of Madagascar


Abstract

Insecticide use remains one of the most common strategies worldwide for controlling household pests and disease vectors, despite growing concerns over misuse, health risks, and the emergence of insecticide resistance. To document household insecticide use and flea infestation across a gradient of plague endemicity in Madagascar, we used a multidisciplinary approach. A descriptive household survey and an observational checklist were implemented with 422 respondents and combined with flea infestation assessment based on flea sampling from small mammals and candle traps. Household insecticide use was primarily reported for pest control (92.4%), mainly targeting fleas (70.3%) and was generally applied reactively rather than preventively. Even though males constituted the majority of respondents (85.0%), mothers are reported to play a primary role in insecticide application (41.4%) and in the purchase (48.2%) of chemical products. Overall, good insecticide practices were observed in 51.3% of households, although the difference between good and poor practice categories was not statistically significant (p = 0.83). Comprehensive understanding of household insecticide use is crucial to implement effective integrated pest management, optimize vector control strategies, minimize selective pressures driving resistance, and protect both human health and the environment.

Acknowledgements

We extend our sincere gratitude to the Centre Valbio Ranomafana for their essential logistical support. We particularly thank Lanto Andrianarijaona Maminirina, Césaire Tianandriatsiferana, Farida Juliette for their invaluable contributions to this study. Our deepest appreciation goes to all participating community members for their time and cooperation, as well as to the local authorities in the villages visited for facilitating this research.

Funding

This study was supported by the Branco Weiss Fellowship—Society in Science (https://brancoweissfellowship.org) and the American Society of Tropical Medicine and Hygiene through the Centennial Travel Award, 2021 (https://www.astmh.org) awarded to Adelaide Miarinjara. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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Annick Onimalala Raveloson.

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Raveloson, A.O., Kassié, D., Ramasindrazana, B. et al. Household insecticide uses and flea infestation in plague-endemic regions of Madagascar.
Sci Rep (2026). https://doi.org/10.1038/s41598-026-58390-5

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  • DOI: https://doi.org/10.1038/s41598-026-58390-5

Keywords

  • Community survey
  • Pest control
  • Plague

  • Pulex irritans

  • Xenopsylla cheopis

  • Yersinia pestis


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