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Housing structure shapes dengue transmission dynamics in a rapidly urbanizing Malaysian district


Abstract

Dengue fever continues to pose a significant public health threat in Malaysia, particularly in peri-urban districts undergoing rapid residential expansion. However, the extent to which housing structures influence dengue transmission remains poorly quantified. This study investigated the temporal, proportional, and spatial dynamics of dengue across five housing categories; landed properties, high-rise residential units, traditional/rural houses, institutional quarters, and others in Kuala Selangor from 2020 to 2024. A total of 5,426 laboratory-confirmed dengue cases obtained from the national e-Notifikasi system were geocoded and classified by housing type. Temporal trends were examined using weekly epidemic curves, proportional contributions were calculated for each housing category, and spatial clustering was assessed using Kernel Density Estimation (KDE) in ArcGIS Pro. Landed properties were the dominant transmission environment, contributing 73.4% of all cases and consistently driving major seasonal peaks during epidemiological weeks 20–35, coinciding with the southwest monsoon. High-rise residential areas accounted for 16.1% of cases and exhibited persistent low-level transmission throughout the year, indicating a potential role as an endemic reservoir between epidemic cycles. Traditional/rural houses (5.5%), institutional quarters (3.4%), and other categories (1.6%) contributed only sporadically. KDE mapping revealed persistent hotspots in central and southern Kuala Selangor, primarily within peri-urban landed housing estates, with smaller recurrent clusters in high-rise complexes. These findings demonstrate that housing typology is a critical determinant of dengue transmission risk. Landed properties amplify monsoon-driven outbreaks through abundant outdoor breeding habitats, while high-rise buildings sustain inter-epidemic transmission via sheltered, indoor breeding sites. Integrating housing-specific intelligence into Malaysia’s Integrated Vector Management (IVM) framework can enable more targeted, proactive, and spatially adaptive dengue prevention strategies.

Data availability

The datasets generated and/or analyzed during the current study are available from the corresponding author on reasonable request. Spatial data layers (e.g., housing classification shapefiles, Kernel Density Estimation outputs) are archived at the Centre of Environmental Health & Safety, Universiti Teknologi MARA (UiTM). All spatial and statistical analyses were conducted using licensed software (ArcGIS Pro 3.1 and R 4.3.2) under institutional agreements, and data sharing follows UiTM and Ministry of Health Malaysia data governance policies.

References

  1. Hadi, Z. A. et al. Geospatial dynamics of dengue fever density In Kuantan, Malaysia: GIS-based approach. Geography, Environ. Sustain. 18(1), 54–64 (2025).

    Google Scholar 

  2. Mantilla-Granados, J. S. et al. Environmental and anthropic factors influencing Aedes aegypti and Aedes albopictus (Diptera: Culicidae), with emphasis on natural infection and dissemination: Implications for an emerging vector in Colombia. PLoS Negl. Trop. Dis. 19(4), e0012605 (2025).

    Google Scholar 

  3. Singh, H., Akhtar, N. & Gupta, S. K. Biology of Mosquitoes. In Mosquitoes: Biology, Pathogenicity and Management 141–163 (Singapore, Springer Nature Singapore, 2024).

    Google Scholar 

  4. AbuBakar, N. et al. The dengue disquisition: A low-cost public housing conundrum in Klang Valley, Malaysia. PLoS ONE 20(1), e0317349 (2025).

    Google Scholar 

  5. Telle, O. et al. Dengue dynamics beyond biological factors: Revealing the nexus between urbanisation planning, and mobilities in Vientiane, Lao PDR. PLOS Negl. Tropic. Diseases 19(6), e0011990 (2025).

    Google Scholar 

  6. Joseph, N. K. et al. Mosquito-borne diseases in urban East African Community region: a scoping review of urban typology research and mosquito genera overlap, 2000–2024. Front. Tropic. Diseases 5, 1499520 (2024).

    Google Scholar 

  7. Islam, S., Haque, C. E., Hossain, S. & Hanesiak, J. Climate variability, dengue vector abundance and dengue fever cases in Dhaka, Bangladesh: a time-series study. Atmosphere 12(7), 905 (2021).

    Google Scholar 

  8. Xu, Z. et al. Spatiotemporal patterns and climatic drivers of severe dengue in Thailand. Sci. Total Environ. 656, 889–901 (2019).

    Google Scholar 

  9. Alam, K. E. et al. Time series analysis of dengue incidence and its association with meteorological risk factors in Bangladesh. PLoS ONE 20(8), e0323238 (2025).

    Google Scholar 

  10. Tayebi, S. et al. A neighborhood-based urban water carrying capacity assessment: analysis of the relationship between spatial-demographic factors and water consumption patterns in Tehran. Iran. Land 11(12), 2203 (2022).

    Google Scholar 

  11. Ghavidelfar, S., Shamseldin, A. Y. & Melville, B. W. A multi-scale analysis of single-unit housing water demand through integration of water consumption, land use and demographic data. Water Resour. Manage 31(7), 2173–2186 (2017).

    Google Scholar 

  12. Mohd Hardy Abdullah, N. A., Dom, N. C., Pradhan, B., Salleh, S. A. & Dapari, R. Temporal associations between microclimate, adult Aedes mosquito indices, and dengue cases at the residence level in Malaysia: Implications for targeted interventions. PLoS ONE 20(2), e0316564 (2025).

    Google Scholar 

  13. Dickin, S. K., Schuster-Wallace, C. J. & Elliott, S. J. Mosquitoes & vulnerable spaces: Mapping local knowledge of sites for dengue control in Seremban and Putrajaya Malaysia. Appl. Geogr. 46, 71–79 (2014).

    Google Scholar 

  14. Woods O, & Randle S. Ecological responsibility in the city: the surfaces and volumes of urban mosquito management. Urban Geography, 1–23 (2025).

  15. Seidahmed, O. M., Lu, D., Chong, C. S., Ng, L. C. & Eltahir, E. A. Patterns of urban housing shape dengue distribution in Singapore at neighborhood and country scales. GeoHealth 2(1), 54–67 (2018).

    Google Scholar 

  16. Rahman, M. S. et al. Ecological, social, and other environmental determinants of dengue vector abundance in urban and rural areas of Northeastern Thailand. Int. J. Environ. Res. Public Health 18(11), 5971 (2021).

    Google Scholar 

  17. Ngugi, H. N. et al. Characterization and productivity profiles of Aedes aegypti (L.) breeding habitats across rural and urban landscapes in western and coastal Kenya. Parasites Vectors 10(1), 331 (2017).

    Google Scholar 

  18. Abdullah, M. S. et al. Impact of waste management on infectious disease control: Evaluating strategies to mitigate dengue transmission and mosquito breeding sites: A systematic review. Integ. Biomed. Res. 8(8), 1–12 (2024).

    Google Scholar 

  19. Fernandez, S. A. et al. Features of the urban environment associated with Aedes aegypti abundance in high-rise public apartments in Singapore: An environmental case-control study. PLoS Negl. Trop. Dis. 17(2), e0011075 (2023).

    Google Scholar 

  20. Sairi, F. A. M., Dom, N. C. & Camalxaman, S. N. Infestation profile of Aedes mosquitoes in multi-storey buildings in Selangor, Malaysia. Procedia Soc. Behav. Sci. 222, 283–289 (2016).

    Google Scholar 

  21. Roslan, M. A. et al. A study on Wolbachia-dengue-carrying Aedes mosquitoes (Diptera: Culicidae) focuses on the sustainability and frequency of Wolbachia in high-rise buildings in Selangor, Malaysia. Appl. Entomol. Zool. 59(3), 225–236 (2024).

    Google Scholar 

  22. Jin, S. et al. Vertical dispersal of Aedes albopictus within multi-story buildings in downtown Shanghai, China. Parasites Vectors 16(1), 176 (2023).

    Google Scholar 

  23. Kolimenakis, A. et al. The role of urbanisation in the spread of Aedes mosquitoes and the diseases they transmit: A systematic review. PLoS Negl. Tropic. Diseases 15(9), e0009631 (2021).

    Google Scholar 

  24. Sarfraz, M. S. et al. Analyzing the spatio-temporal relationship between dengue vector larval density and land-use using factor analysis and spatial ring mapping. BMC Public Health 12(1), 853 (2012).

    Google Scholar 

  25. Aris NAM, Fathi MS, Harun AN, & Mohamed Z. Spatial Pattern of Affordability and Overhang in Selangor. In IOP Conference Series: Earth and Environmental Science. 012057. (IOP Publishing 2025)

  26. Jaafar HZ, & Ashraf MA. 1 Climate, Ecosystem, Flora, and Fauna. Soils of Malaysia (2017)

  27. Herath, J. M. K., De Silva, W. P. P., Weeraratne, T. C. & Karunaratne, S. P. Breeding habitat preference of the dengue vector mosquitoes Aedes aegypti and Aedes albopictus from urban, semiurban, and rural areas in Kurunegala District, Sri Lanka. J. Trop. Med. 2024(1), 4123543 (2024).

    Google Scholar 

  28. Hossain, K. et al. Spatio-temporal patterns of dengue in Bangladesh during 2019 to 2023: Implications for targeted control strategies. PLoS Negl. Trop. Dis. 18(9), e0012503 (2024).

    Google Scholar 

  29. Zhaki, Z. A., Dom, N. C. & Alhothily, I. A. Study on the distribution and abundance of Aedes aegypti and Aedes albopictus in different environment settings for high-rise buildings. Malaysian J. Med. Health Sci. 15, 102–108 (2019).

    Google Scholar 

  30. Ab Hamid, N. et al. Vertical infestation profile of Aedes in selected urban high-rise residences in Malaysia. Tropic. Med. Infect. Disease 5(3), 114 (2020).

    Google Scholar 

  31. Montgomery, M. R., Pinchoff, J. & Chuang, E. K. Cities and their environments. In International handbook of population and environment 349–374 (Springer International Publishing, 2021).

    Google Scholar 

  32. Marti, R. et al. A mapping review on urban landscape factors of dengue retrieved from earth observation data, GIS techniques, and survey questionnaires. Remote Sensing 12(6), 932 (2020).

    Google Scholar 

  33. Dom, N. C. et al. Barriers and opportunities for community engagement in UAV-based dengue management in rural Malaysia. PLoS ONE 20(4), e0322321 (2025).

    Google Scholar 

  34. Samsudin, N. A., Othman, H., Siau, C. S. & Zaini, Z. I. I. Exploring community needs in combating aedes mosquitoes and dengue fever: a study with urban community in the recurrent hotspot area. BMC Public Health 24(1), 1651 (2024).

    Google Scholar 

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Acknowledgements

The authors thank the Faculty of Health Sciences, Universiti Teknologi MARA (UiTM) for institutional support, and the Kuala Selangor District Health Office for providing access to surveillance data. Appreciation is extended to the drone operations and GIS technical team for assistance in geocoding and spatial validation. The authors also acknowledge the Civil Aviation Authority of Malaysia (CAAM) for facilitating drone operation compliance and the Shah Alam City Council (MBSA) for logistical coordination.

Funding

This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

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Authors and Affiliations

Authors

Contributions

N.C.D., A.N.S.H., M.N.S., N.A.A.L., M.I.R. and R.D conceived the study, supervised overall execution, and verified the underlying data. N.C.D., Z.A.M.F., and N.M.Y. designed the analytical framework and performed data validation. N.C.D. and M.A.O. conducted the statistical and spatial analyses, and prepared the figures. N.C.D., S.A.S., and R.D. interpreted the results and drafted the initial manuscript. All authors reviewed, revised, and approved the final version prior to submission.

Corresponding author

Correspondence to
Nazri Che Dom.

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Competing interests

The authors declare no competing interests.

Ethical approval

This study utilized secondary surveillance data obtained with formal approval from the Medical Research and Ethics Committee (MREC), Ministry of Health Malaysia (NMRR ID: 25–02921-CR1). Ethical clearance was granted on 1 October 2025, valid until 1 October 2026. All procedures were conducted in accordance with national data protection regulations and institutional ethical standards. No human subjects were directly involved, and all data were anonymized prior to analysis. Data were used solely for research purposes under strict confidentiality.

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Dom, N.C., Hisyam, A.N.S., Saeman, M.N. et al. Housing structure shapes dengue transmission dynamics in a rapidly urbanizing Malaysian district.
Sci Rep (2026). https://doi.org/10.1038/s41598-026-35904-9

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  • DOI: https://doi.org/10.1038/s41598-026-35904-9

Keywords

  • Dengue transmission
  • Housing typology
  • Spatial epidemiology
  • Temporal analysis
  • Vector management


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