Aurelia Butler

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    in Environment

    Recycling plastics from research labs

    In 2019, MIT’s Environment, Health, and Safety (EHS) Office collaborated with several research labs in the Department of Biology to determine the feasibility of recycling clean lab plastics. Based on early successes with waste isolation and plastics collection, EHS collaborated with GreenLabs Recycling, a local startup, to remove and recycle lab plastics from campus. It was a huge success.

    Today, EHS spearheads the campus Lab Plastics Recycling Program, and its EHS technicians regularly gather clean lab plastics from 212 MIT labs, transferring them to GreenLabs for recycling. Since its pilot stage, the number of labs participating in the program has grown, increasing the total amount of plastic gathered and recycled. In 2020, EHS collected 170 pounds of plastic waste per week from participating labs. That increased to 250 pounds per week in 2021. In 2022, EHS collected a total of 19,000 pounds, or 280 pounds of plastic per week.

    Joanna Buchthal, a research assistant with the MIT Media Lab, indicates that, prior to joining the EHS Lab Plastics Recycling Program, “our laboratory was continuously troubled by the substantial volume of plastic waste we produced and disheartened by our inability to recycle it. We frequently addressed this issue during our group meetings and explored various ways to repurpose our waste, yet we never arrived at a viable solution.”

    The EHS program now provides a solution to labs facing similar challenges with plastics use. After pickup and removal, the plastics are shredded and sold as free stock for injection mold product manufacturing. Buchthal says, “My entire lab is delighted to recycle our used tip boxes and transform them into useful items for other labs!”

    Recently, GreenLabs presented EHS with a three-gallon bucket that local manufacturers produced from 100 percent recycled plastic gathered from MIT labs. No fillers or additives were used in its production.

    Keeping it clean

    The now-growing EHS service and operation started as a pilot. In June 2019, MIT restricted which lab-generated items could be placed in single-stream recycling. MIT’s waste vendors were no longer accepting possibly contaminated waste, such as gloves, pipette tip boxes, bottles, and other plastic waste typically generated in biological research labs. The waste vendors would audit MIT’s single-stream recycling and reject items if they observed any contamination.

    Facing these challenges, the EHS coordinator for biology, John Fucillo, and several EHS representatives from the department met with EHS staff to brainstorm potential recycling solutions. Ensuring the decontamination of the plastic and coordinating its removal in an efficient way were the primary challenges for the labs, says Fucillo, who shared his and lab members’ concerns about the amount of plastic being thrown away with Mitch Galanek, EHS associate director for the Radiation Protection Program. Galanek says, “I immediately recognized the frustration expressed by John and other lab contacts as an opportunity to collaborate.”

    In July 2019, Galanek and a team of EHS technicians began segregating and collecting clean plastic waste from several labs within the biology department. EHS provided the labs with collection containers, and its technicians managed the waste removal over a four-month period, which produced a snapshot of the volume and type of waste generated. An audit of the waste determined that approximately 80 percent of the clean plastic waste generated was empty pipette tip boxes and conical tube racks.

    Based on these data, EHS launched a lab plastics recycling pilot program in November 2019. Labs from the Department of Biology and the Koch Institute for Integrative Cancer Research were invited to participate by recycling their clean, uncontaminated pipette tip boxes and conical tube racks. In addition to providing these labs with collection boxes and plastic liners, EHS also developed an online waste collection request tool to submit plastic pickup requests. EHS also collected the waste containers once they were full.

    Assistant professor of biology Seychelle Vos joined the pilot program as soon as she started her lab in fall 2019. Vos shares that “we already use pipette tips boxes that produce minimal waste, and this program allows us to basically recycle any part of the box except for tips. Pipette boxes are a significant source of plastic waste. This program helps us to be more environmentally and climate friendly.” 

    Given the increased participation in the program, EHS technician Dave Pavone says that plastic pickup is now a “regular component of our work schedules.”

    Together, the EHS technicians, commonly known as “techs,” manage the pickup of nearly 300 plastic collection containers across campus. Normand Desrochers, one of the EHS techs, shares that each morning he plans his pickup route “to get the job done efficiently.” While weekly pickups are a growing part of their schedules, Desrochers notes that everyone has been “super appreciative in what we do for their labs. And what we do makes their job that much easier, being able to focus on their research.”

    Barbara Karampalas, a lab operations manager within the Department of Biological Engineering, is one of many to express appreciation for the program: “We have a fairly large lab with 35 researchers, so we generate a lot of plastic waste … [and] knowing how many tip boxes we were using concerned me. I really appreciate the effort EHS has made to implement this program to help us reduce our impact on the environment.” The program also “makes people in the lab more aware of the issue of plastic waste and MIT’s commitment to reduce its impact on the environment,” says Karampalas.

    Looking ahead

    MIT labs continue to enthusiastically embrace the EHS Lab Plastics Recycling Program: 112 faculty across 212 labs are currently participating in the program. While only empty pipette tip boxes and conical tube racks are currently collected, EHS is exploring which lab plastics could be manufactured into products for use in the labs and repeatedly recycled. Specifically, the EHS Office is considering whether recycled plastic could be used to produce secondary containers for collecting hazardous waste and benchtop transfer containers used for collecting medical waste. As Seychelle notes, “Most plastics cannot be recycled in the current schemes due to their use in laboratory science.”

    Says Fucillo, “Our hope is that this program can be expanded to include other products which could be recycled from the wet labs.” John MacFarlane, research engineer and EHS coordinator for civil and environmental engineering, echoes this sentiment: “With plastic recycling facing economic constraints, this effort by the Institute deserves to be promoted and, hopefully, expanded.”

    “Having more opportunities to recycle ’biologically clean’ plastics would help us have a smaller carbon footprint,” agrees Vos. “We love this program and hope it expands further!”

    MIT labs interested in participating in the EHS Lab Plastics Recycling Program can contact pipetip@mit.edu to learn more. More

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    in Environment

    Even as temperatures rise, this hydrogel material keeps absorbing moisture

    The vast majority of absorbent materials will lose their ability to retain water as temperatures rise. This is why our skin starts to sweat and why plants dry out in the heat. Even materials that are designed to soak up moisture, such as the silica gel packs in consumer packaging, will lose their sponge-like properties as their environment heats up.

    But one material appears to uniquely resist heat’s drying effects. MIT engineers have now found that polyethylene glycol (PEG) — a hydrogel commonly used in cosmetic creams, industrial coatings, and pharmaceutical capsules — can absorb moisture from the atmosphere even as temperatures climb.

    The material doubles its water absorption as temperatures climb from 25 to 50 degrees Celsius (77 to 122 degrees Fahrenheit), the team reports.

    PEG’s resilience stems from a heat-triggering transformation. As its surroundings heat up, the hydrogel’s microstructure morphs from a crystal to a less organized “amorphous” phase, which enhances the material’s ability to capture water.

    Based on PEG’s unique properties, the team developed a model that can be used to engineer other heat-resistant, water-absorbing materials. The group envisions such materials could one day be made into devices that harvest moisture from the air for drinking water, particularly in arid desert regions. The materials could also be incorporated into heat pumps and air conditioners to more efficiently regulate temperature and humidity.

    “A huge amount of energy consumption in buildings is used for thermal regulation,” says Lenan Zhang, a research scientist in MIT’s Department of Mechanical Engineering. “This material could be a key component of passive climate-control systems.”

    Zhang and his colleagues detail their work in a study appearing today in Advanced Materials. MIT co-authors include Xinyue Liu, Bachir El Fil, Carlos Diaz-Marin, Yang Zhong, Xiangyu Li, and Evelyn Wang, along with Shaoting Lin of Michigan State University.

    Against intuition

    Evelyn Wang’s group in MIT’s Device Research Lab aims to address energy and water challenges through the design of new materials and devices that sustainably manage water and heat. The team discovered PEG’s unusual properties as they were assessing a slew of similar hydrogels for their water-harvesting abilities.

    “We were looking for a high-performance material that could capture water for different applications,” Zhang says. “Hydrogels are a perfect candidate, because they are mostly made of water and a polymer network. They can simultaneously expand as they absorb water, making them ideal for regulating humidity and water vapor.”

    The team analyzed a variety of hydrogels, including PEG, by placing each material on a scale that was set within a climate-controlled chamber. A material became heavier as it absorbed more moisture. By recording a material’s changing weight, the researchers could track its ability to absorb moisture as they tuned the chamber’s temperature and humidity.

    What they observed was typical of most materials: as the temperature increased, the hyrogels’ ability to capture moisture from the air decreased. The reason for this temperature-dependence is well-understood: With heat comes motion, and at higher temperatures, water molecules move faster and are therefore more difficult to contain in most materials.

    “Our intuition tells us that at higher temperatures, materials tend to lose their ability to capture water,” says co-author Xinyue Liu. “So, we were very surprised by PEG because it has this inverse relationship.”

    In fact, they found that PEG grew heavier and continued to absorb water as the researchers raised the chamber’s temperature from 25 to 50 degrees Celsius.

    “At first, we thought we had measured some errors, and thought this could not be possible,” Liu says. “After we double-checked everything was correct in the experiment, we realized this was really happening, and this is the only known material that shows increasing water absorbing ability with higher temperature.”

    A lucky catch

    The group zeroed in on PEG to try and identify the reason for its unusual, heat-resilient performance. They found that the material has a natural melting point at around 50 degrees Celsius, meaning that the hydrogel’s normally crystal-like microstructure completely breaks down and transforms into an amorphous phase. Zhang says that this melted, amorphous phase provides more opportunity for polymers in the material to grab hold of any fast-moving water molecules.

    “In the crystal phase, there might be only a few sites on a polymer available to attract water and bind,” Zhang says. “But in the amorphous phase, you might have many more sites available. So, the overall performance can increase with increased temperature.”

    The team then developed a theory to predict how hydrogels absorb water, and showed that the theory could also explain PEG’s unusual behavior if the researchers added a “missing term” to the theory. That missing term was the effect of phase transformation. They found that when they included this effect, the theory could predict PEG’s behavior, along with that of other temperature-limiting hydrogels.

    The discovery of PEG’s unique properties was in large part by chance. The material’s melting temperature just happens to be within the range where water is a liquid, enabling them to catch PEG’s phase transformation and its resulting super-soaking behavior. The other hydrogels happen to have melting temperatures that fall outside this range. But the researchers suspect that these materials are also capable of similar phase transformations once they hit their melting temperatures.

    “Other polymers could in theory exhibit this same behavior, if we can engineer their melting points within a selected temperature range,” says team member Shaoting Lin.

    Now that the group has worked out a theory, they plan to use it as a blueprint to design materials specifically for capturing water at higher temperatures.

    “We want to customize our design to make sure a material can absorb a relatively high amount of water, at low humidity and high temperatures,” Liu says. “Then it could be used for atmospheric water harvesting, to bring people potable water in hot, arid environments.”

    This research was supported, in part, by U.S. Department of Energy’s Office of Energy Efficiency and Renewable Energy. More

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    in Environment

    MIT PhD students honored for their work to solve critical issues in water and food

    In 2017, the Abdul Latif Jameel Water and Food Systems Lab (J-WAFS) initiated the J-WAFS Fellowship Program for outstanding MIT PhD students working to solve humankind’s water-related challenges. Since then, J-WAFS has awarded 18 fellowships to students who have gone on to create innovations like a pump that can maximize energy efficiency even with changing flow rates, and a low-cost water filter made out of sapwood xylem that has seen real-world use in rural India. Last year, J-WAFS expanded eligibility to students with food-related research. The 2022 fellows included students working on micronutrient deficiency and plastic waste from traditional food packaging materials. 

    Today, J-WAFS has announced the award of the 2023-24 fellowships to Gokul Sampath and Jie Yun. A doctoral student in the Department of Urban Studies and planning, Sampath has been awarded the Rasikbhai L. Meswani Fellowship for Water Solutions, which is supported through a generous gift from Elina and Nikhil Meswani and family. Yun, who is in the Department of Civil and Environmental Engineering, received a J-WAFS Fellowship for Water and Food Solutions, which is funded by the J-WAFS Research Affiliate Program. Currently, Xylem, Inc. and GoAigua are J-WAFS’ Research Affiliate companies. A review committee comprised of MIT faculty and staff selected Sampath and Yun from a competitive field of outstanding graduate students working in water and food who were nominated by their faculty advisors. Sampath and Yun will receive one academic semester of funding, along with opportunities for networking and mentoring to advance their research.

    “Both Yun and Sampath have demonstrated excellence in their research,” says J-WAFS executive director Renee J. Robins. “They also stood out in their communication skills and their passion to work on issues of agricultural sustainability and resilience and access to safe water. We are so pleased to have them join our inspiring group of J-WAFS fellows,” she adds.

    Using behavioral health strategies to address the arsenic crisis in India and Bangladesh

    Gokul Sampath’s research centers on ways to improve access to safe drinking water in developing countries. A PhD candidate in the International Development Group in the Department of Urban Studies and Planning, his current work examines the issue of arsenic in drinking water sources in India and Bangladesh. In Eastern India, millions of shallow tube wells provide rural households a personal water source that is convenient, free, and mostly safe from cholera. Unfortunately, it is now known that one-in-four of these wells is contaminated with naturally occurring arsenic at levels dangerous to human health. As a result, approximately 40 million people across the region are at elevated risk of cancer, stroke, and heart disease from arsenic consumed through drinking water and cooked food. 

    Since the discovery of arsenic in wells in the late 1980s, governments and nongovernmental organizations have sought to address the problem in rural villages by providing safe community water sources. Yet despite access to safe alternatives, many households still consume water from their contaminated home wells. Sampath’s research seeks to understand the constraints and trade-offs that account for why many villagers don’t collect water from arsenic-safe government wells in the village, even when they know their own wells at home could be contaminated.

    Before coming to MIT, Sampath received a master’s degree in Middle East, South Asian, and African studies from Columbia University, as well as a bachelor’s degree in microbiology and history from the University of California at Davis. He has long worked on water management in India, beginning in 2015 as a Fulbright scholar studying households’ water source choices in arsenic-affected areas of the state of West Bengal. He also served as a senior research associate with the Abdul Latif Jameel Poverty Action Lab, where he conducted randomized evaluations of market incentives for groundwater conservation in Gujarat, India. Sampath’s advisor, Bishwapriya Sanyal, the Ford International Professor of Urban Development and Planning at MIT, says Sampath has shown “remarkable hard work and dedication.” In addition to his classes and research, Sampath taught the department’s undergraduate Introduction to International Development course, for which he received standout evaluations from students.

    This summer, Sampath will travel to India to conduct field work in four arsenic-affected villages in West Bengal to understand how social influence shapes villagers’ choices between arsenic-safe and unsafe water sources. Through longitudinal surveys, he hopes to connect data on the social ties between families in villages and the daily water source choices they make. Exclusionary practices in Indian village communities, especially the segregation of water sources on the basis of caste and religion, has long been suspected to be a barrier to equitable drinking water access in Indian villages. Yet despite this, planners seeking to expand safe water access in diverse Indian villages have rarely considered the way social divisions within communities might be working against their efforts. Sampath hopes to test whether the injunctive norms enabled by caste ties constrain villagers’ ability to choose the safest water source among those shared within the village. When he returns to MIT in the fall, he plans to dive into analyzing his survey data and start work on a publication.

    Understanding plant responses to stress to improve crop drought resistance and yield

    Plants, including crops, play a fundamental role in Earth’s ecosystems through their effects on climate, air quality, and water availability. At the same time, plants grown for agriculture put a burden on the environment as they require energy, irrigation, and chemical inputs. Understanding plant/environment interactions is becoming more and more important as intensifying drought is straining agricultural systems. Jie Yun, a PhD student in the Department of Civil and Environmental Engineering, is studying plant response to drought stress in the hopes of improving agricultural sustainability and yield under climate change.  Yun’s research focuses on genotype-by-environment interaction (GxE.) This relates to the observation that plant varieties respond to environmental changes differently. The effects of GxE in crop breeding can be exploited because differing environmental responses among varieties enables breeders to select for plants that demonstrate high stress-tolerant genotypes under particular growing conditions. Yun bases her studies on Brachypodium, a model grass species related to wheat, oat, barley, rye, and perennial forage grasses. By experimenting with this species, findings can be directly applied to cereal and forage crop improvement. For the first part of her thesis, Yun collaborated with Professor Caroline Uhler’s group in the Department of Electrical Engineering and Computer Science and the Institute for Data, Systems, and Society. Uhler’s computational tools helped Yun to evaluate gene regulatory networks and how they relate to plant resilience and environmental adaptation. This work will help identify the types of genes and pathways that drive differences in drought stress response among plant varieties.  David Des Marais, the Cecil and Ida Green Career Development Professor in the Department of Civil and Environmental Engineering, is Yun’s advisor. He notes, “throughout Jie’s time [at MIT] I have been struck by her intellectual curiosity, verging on fearlessness.” When she’s not mentoring undergraduate students in Des Marais’ lab, Yun is working on the second part of her project: how carbon allocation in plants and growth is affected by soil drying. One result of this work will be to understand which populations of plants harbor the necessary genetic diversity to adapt or acclimate to climate change. Another likely impact is identifying targets for the genetic improvement of crop species to increase crop yields with less water supply. Growing up in China, Yun witnessed environmental issues springing from the development of the steel industry, which caused contamination of rivers in her hometown. On one visit to her aunt’s house in rural China, she learned that water pollution was widespread after noticing wastewater was piped outside of the house into nearby farmland without being treated. These experiences led Yun to study water supply and sewage engineering for her undergraduate degree at Shenyang Jianzhu University. She then went on to complete a master’s program in civil and environmental engineering at Carnegie Mellon University. It was there that Yun discovered a passion for plant-environment interactions; during an independent study on perfluorooctanoic sulfonate, she realized the amazing ability of plants to adapt to environmental changes, toxins, and stresses. Her goal is to continue researching plant and environment interactions and to translate the latest scientific findings into applications that can improve food security. More

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    in Security

    Scientists uncover the amazing way sandgrouse hold water in their feathers

    Many birds’ feathers are remarkably efficient at shedding water — so much so that “like water off a duck’s back” is a common expression. Much more unusual are the belly feathers of the sandgrouse, especially Namaqua sandgrouse, which absorb and retain water so efficiently the male birds can fly more than 20 kilometers from a distant watering hole back to the nest and still retain enough water in their feathers for the chicks to drink and sustain themselves in the searing deserts of Namibia, Botswana, and South Africa.

    How do those feathers work? While scientists had inferred a rough picture, it took the latest tools of microscopy, and patient work with a collection of sandgrouse feathers, to unlock the unique structural details that enable the feathers to hold water. The findings appear today in the Journal of the Royal Society Interface, in a paper by Lorna Gibson, the Matoula S. Salapatas Professor of Materials Science and Engineering and a professor of mechanical engineering at MIT, and Professor Jochen Mueller of Johns Hopkins University.

    The unique water-carrying ability of sandgrouse feathers was first reported back in 1896, Gibson says, by E.G.B. Meade-Waldo, who was breeding the birds in captivity. “He saw them behaving like this, and nobody believed him! I mean, it just sounded so outlandish,” Gibson says.

    In 1967, Tom Cade and Gordon MacLean reported detailed observations of the birds at watering holes, in a study that proved the unique behavior was indeed real. The scientists found that male sandgrouse feathers could hold about 25 milliliters of water, or about a tenth of a cup, after the bird had spent about five minutes dipping in the water and fluffing its feathers.

    About half of that amount can evaporate during the male bird’s half-hour-long flight back to the nest, where the chicks, which cannot fly for about their first month, drink the remainder straight from the feathers.

    Cade and MacLean “had part of the story,” Gibson says, but the tools didn’t exist at the time to carry out the detailed imaging of the feather structures that the new study was able to do.

    Gibson and Mueller carried out their study using scanning electron microscopy, micro-computed tomography, and video imaging. They borrowed Namaqua sandgrouse belly feathers from Harvard University’s Museum of Comparative Zoology, which has a collection of specimens of about 80 percent of the world’s birds.

    Bird feathers in general have a central shaft, from which smaller barbs extend, and then smaller barbules extend out from those. Sandgrouse feathers are structured differently, however. In the inner zone of the feather, the barbules have a helically coiled structure close to their base and then a straight extension. In the outer zone of the feather, the barbules lack the helical coil and are simply straight. Both parts lack the grooves and hooks that hold the vane of contour feathers together in most other birds.
    Video of water spreading through the specialized sandgrouse feathers, under magnification, shows the uncoiling and spreading of the feather’s barbules as they become wet. Initially, most barbules in the outer zone of the feather form tubular features.Credit: Specimen #142928, Museum of Comparative Zoology, Harvard University © President and Fellows of Harvard College.

    When wetted, the coiled portions of the barbules unwind and rotate to be perpendicular to the vane, producing a dense forest of fibers that can hold water through capillary action. At the same time, the barbules in the outer zone curl inward, helping to hold the water in.

    The microscopy techniques used in the new study allowed the dimensions of the different parts of the feather to be measured. In the inner zone, the barb shafts are large and stiff enough to provide a rigid base about which the other parts of the feather deform, and the barbules are small and flexible enough that surface tension is sufficient to bend the straight extensions into tear-like structures that hold water. And in the outer zone, the barb shafts and barbules are smaller still, allowing them to curl around the inner zone, further retaining water.

    While previous work had suggested that surface tension produced the water retention characteristics, “what we did was make measurements of the dimensions and do some calculations to show that that’s what is actually happening,” Gibson says. Her group’s work demonstrated that the varying stiffnesses of the different feather parts plays a key role in their ability to hold water.

    The study was mostly driven by intellectual curiosity about this unique behavioral phenomenon, Gibson says. “We just wanted to see how it works. The whole story just seemed so interesting.” But she says it might lead to some useful applications. For example, in desert regions where water is scarce but fog and dew regularly occur, such as in Chile’s Atacama Desert, some adaptation of this feather structure might be incorporated into the systems of huge nets that are used to collect water. “You could imagine this could be a way to improve those systems,” she says. “A material with this kind of structure might be more effective at fog harvesting and holding the water.”

    “This fascinating and in-depth study reveals how the different parts of the sandgrouse’s belly feathers — including the microscopic barb shafts and barbules — work together to hold water,” says Mary Caswell Stoddard, an evolutionary biologist at Princeton University, who was not associated with this study. “By using a suite of advanced imaging techniques to describe the belly feathers and estimate their bending stiffnesses, Mueller and Gibson add rich new details to our understanding of the sandgrouse’s water-carrying feathers. … This study may inspire others to take a closer look at diverse feather microstructures across bird species — and to wonder whether these structures, as in sandgrouse, help support unusual or surprising functions.”

    The work was partly supported by the National Science Foundation and the Matoula S. Salapatas Professorship in Materials Science and Engineering at MIT. More

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    in Environment

    A new microneedle-based drug delivery technique for plants

    Increasing environmental conditions caused by climate change, an ever-growing human population, scarcity of arable land, and limited resources are pressuring the agriculture industry to adopt more sustainable and precise practices that foster more efficient use of resources (e.g., water, fertilizers, and pesticides) and mitigation of environmental impacts. Developing delivery systems that efficiently deploy agrochemicals such as micronutrients, pesticides, and antibiotics in crops will help ensure high productivity and high produce quality, while minimizing the waste of resources, is crucial.

    Now, researchers in Singapore and the U.S. have developed the first-ever microneedle-based drug delivery technique for plants. The method can be used to precisely deliver controlled amounts of agrochemicals to specific plant tissues for research purposes. When applied in the field, it could one day be used in precision agriculture to improve crop quality and disease management.

    The work is led by researchers from the Disruptive and Sustainable Technologies for Agricultural Precision (DiSTAP) interdisciplinary research group at the Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, and their collaborators from MIT and the Temasek Life Sciences Laboratory (TLL).

    Current and standard practices for agrochemical application in plants, such as foliar spray, are inefficient due to off-target application, quick runoff in the rain, and actives’ rapid degradation. These practices also cause significant detrimental environmental side effects, such as water and soil contamination, biodiversity loss, and degraded ecosystems; and public health concerns, such as respiratory problems, chemical exposure, and food contamination.

    The novel silk-based microneedles technique circumvents these limitations by deploying and targeting a known amount of payload directly into a plant’s deep tissues, which will lead to higher efficacy of plant growth and help with disease management. The technique is minimally invasive, as it delivers the compound without causing long-term damage to the plants, and is environmentally sustainable. It minimizes resource wastage and mitigates the adverse side effects caused by agrochemical contamination of the environment. Additionally, it will help foster precise agricultural practices and provide new tools to study plants and design crop traits, helping to ensure food security.

    Described in a paper titled “Drug Delivery in Plants Using Silk Microneedles,” published in a recent issue of Advanced Materials, the research studies the first-ever polymeric microneedles used to deliver small compounds to a wide variety of plants and the plant response to biomaterial injection. Through gene expression analysis, the researchers could closely examine the reactions to drug delivery following microneedle injection. Minimal scar and callus formation were observed, suggesting minimal injection-induced wounding to the plant. The proof of concept provided in this study opens the door to plant microneedles’ application in plant biology and agriculture, enabling new means to regulate plant physiology and study metabolisms via efficient and effective delivery of payloads.

    The study optimized the design of microneedles to target the systemic transport system in Arabidopsis (mouse-ear cress), the chosen model plant. Gibberellic acid (GA3), a widely used plant growth regulator in agriculture, was selected for the delivery. The researchers found that delivering GA3 through microneedles was more effective in promoting growth than traditional methods (such as foliar spray). They then confirmed the effectiveness using genetic methods and demonstrated that the technique is applicable to various plant species, including vegetables, cereals, soybeans, and rice.

    Professor Benedetto Marelli, co-corresponding author of the paper, principal investigator at DiSTAP, and associate professor of civil and environmental engineering at MIT, shares, “The technique saves resources as compared to current methods of agrochemical delivery, which suffer from wastage. During the application, the microneedles break through the tissue barriers and release compounds directly inside the plants, avoiding agrochemical losses. The technique also allows for precise control of the amounts of the agrochemical used, ensuring high-tech precision agriculture and crop growth to optimize yield.”

    “The first-of-its-kind technique is revolutionary for the agriculture industry. It also minimizes resource wastage and environmental contamination. In the future, with automated microneedle application as a possibility, the technique may be used in high-tech outdoor and indoor farms for precise agrochemical delivery and disease management,” adds Yunteng Cao, the first author of the paper and postdoc at MIT.

    “This work also highlights the importance of using genetic tools to study plant responses to biomaterials. Analyzing these responses at the genetic level offers a comprehensive understanding of these responses, thereby serving as a guide for the development of future biomaterials that can be used across the agri-food industry,” says Sally Koh, the co-first author of this work and PhD candidate from NUS and TLL.

    The future seems promising as Professor Daisuke Urano, co-corresponding author of the paper, TLL principal investigator, and NUS adjunct assistant professor elaborates, “Our research has validated the use of silk-based microneedles for agrochemical application, and we look forward to further developing the technique and microneedle design into a scalable model for manufacturing and commercialization. At the same time, we are also actively investigating potential applications that could have a significant impact on society.”

    The study of drug delivery in plants using silk microneedles expanded upon previous research supervised by Marelli. The original idea was conceived by SMART and MIT: Marelli, Cao, and Professor Nam-Hai Chua, co-lead principal investigator at DiSTAP. Researchers from TLL and the National University of Singapore, Professor Urano Daisuke and Koh, joined the study to contribute biological perspectives. The research is carried out by SMART and supported by the National Research Foundation Singapore (NRF) under its Campus for Research Excellence And Technological Enterprise (CREATE) program.

    SMART was established by MIT and NRF in 2007. SMART is the first entity in CREATE, developed by NRF. SMART serves as an intellectual and innovation hub for research interactions between MIT and Singapore, undertaking cutting-edge research in areas of interest to both parties. SMART currently comprises an Innovation Center and interdisciplinary research groups: Antimicrobial Resistance, Critical Analytics for Manufacturing Personalized-Medicine, DiSTAP, Future Urban Mobility, and Low Energy Electronic Systems. More

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    in Environment

    Engineering for social impact

    A desire to make meaningful contributions to society has influenced Runako Gentles’ path in life. Gentles grew up in Jamaica with a supportive extended family that instilled in him his connection to his faith and his aspiration to aim for greatness.

    “While growing up, I was encouraged to live a life that could potentially bring about major positive changes in my family and many other people’s lives,” says the MIT junior.

    One of those pathways his parents encouraged is pursuing excellence in academics.

    Gentles attended Campion College, a Jesuit high school in Jamaica for academically high-achieving students. Gentles was valedictorian and even won an award “for the member of the valedictory class who most closely resembles the ideal of intellectual competence, openness to growth, and commitment to social justice.”

    Although he did well in all subjects, he naturally gravitated toward biology and chemistry. “There are certain subjects people just make sense of material much faster, and high school biology and chemistry were those subjects for me,” he says. His love of learning often surprised friends and classmates when he could recall science concepts and definitions years later.  

    For several years Gentles wanted to pursue the field of medicine. He remembers becoming more excited about the career of a surgeon after reading a book on the story of retired neurosurgeon Ben Carson. During his advanced studies at Campion, he attended a career event and met with a neurosurgeon who invited him and other classmates to watch a surgical procedure. Gentles had the unique learning experience to observe a spinal operation. Around that same time another learning opportunity presented itself. His biology teacher recommended he apply to a Caribbean Science Foundation initiative called Student Program for Innovation, Science, and Engineering (SPISE) to explore careers in science, technology, engineering, and math. The intensive residential summer program for Caribbean students is modeled after the Minority Introduction to Engineering and Science (MITES) program at MIT. Cardinal Warde, a professor of electrical engineering at MIT who is also from the Caribbean, serves as the faculty director for both MITES and SPISE. The program was Gentles’ first major exposure to engineering.

    “I felt like I was in my first year of college at SPISE. It was an amazing experience and it helped me realize the opportunities that an engineering career path offers,” Gentles says. He excelled in the SPISE program, even winning one of the program’s highest honors for demonstrating overall excellence and leadership.

    SPISE was profoundly impactful to Gentles and he decided to pursue engineering at MIT. While further exploring his engineering interests before his first year at MIT, he remembers reading an article that piqued his interest in industry sectors that met basic human and societal needs.

    “I started thinking more about engineering and ethics,” says Gentles. He wanted to spend his time learning how to use science and engineering to make meaningful change in society.  “I think back to wanting to be a doctor for many years to help sick people, but I took it a step further. I wanted to get closer to addressing some of the root causes of deaths, illnesses, and the poor quality of life for billions of people,” he says of his decision to pursue a degree in civil and environmental engineering.

    Gentles spent his first semester at MIT working as a remote student when the Covid pandemic shut down in-person learning. He participated in 1.097 (Introduction to Civil and Environmental Engineering Research) during the January Independent Activities Period, in which undergraduates work one-on-one with graduate students or postdoc mentors on research projects that align with their interests. Gentles worked in the lab of Ruben Juanes exploring the use of machine learning to analyze earthquake data to determine whether different geologic faults in Puerto Rico resulted in distinguishable earthquake clusters. He joined the lab of Desiree Plata in the summer of his sophomore year on another undergraduate research opportunity (UROP) project, analyzing diesel range organic compounds in water samples collected from shallow groundwater sources near hydraulic fracking sites in West Virginia. The experience even led Gentles to be a co-author in his graduate student mentor’s abstract proposal for the American Geophysical Union Fall Meeting 2022 conference.  

    Gentles says he found the Department of Civil and Environmental Engineering a place for him to have the big-picture mindset of thinking about how technology is going to affect the environment, which ultimately affects society. “Choosing this department was not just about gaining the technical knowledge that most interested me. I wanted to be in a space where I would significantly develop my mindset of using innovation to bring more harmony between society and the environment,” says Gentles.

    Outside of the classroom, learning acoustic guitar is a passion for Gentles. He plays at social events for Cru, a Christian community at MIT, where he serves as a team leader. He credits Cru with helping him feel connected to a lot of different people, even outside of MIT.

    He’s also a member of the Bernard M. Gordon-MIT Engineering Leadership Program, which helps undergraduates gain and hone leadership skills to prepare them for careers in engineering. After learning and exploring more UROPs and classes in civil and environmental engineering, he aspires to hold a position of leadership where he can use his environmental knowledge to impact human lives.

    “Mitigating environmental issues can sometimes be a very complicated endeavor involving many stakeholders,” Gentles says. “We need more bright minds to be thinking of creative ways to address these pressing problems. We need more leaders helping to make society more harmonious with our planet.” More

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    in Environment

    Benjamin Mangrum receives the 2023 Levitan Prize in the Humanities

    Benjamin Mangrum, assistant professor of literature at MIT, has been awarded the 2023 Levitan Prize in the Humanities. This award, presented each year by a faculty committee, empowers a member of the MIT School of Humanities, Arts, and Social Sciences (SHASS) faculty with funding to enable research in their field. With an award of $30,000, this annual prize continues to power substantial projects among the members of the SHASS community.

    Mangrum will use the award to support research for his upcoming book, which is a cultural and intellectual history of environmental rights. In the book, Mangrum discusses the cultural structures that have helped link rights language to environmental concerns. Mangrum plans to use the funding from the Levitan Prize for research into a chapter involving literary personhood.

    “Assertions of environmental rights are typically the result of pragmatic or strategic alignments between, say, naturalists and labor organizers or indigenous communities and governments,” he writes. “My book examines the compromises and conceptual negotiations that occur for ‘environmental rights’ to be a workable concept.”

    The notion of environmental rights can refer to the right of citizens to live in a healthy environment, but it can also include the attribution of rights to nonhuman entities. Such designation received increased attention when New Zealand gave the Whanganui River a legal identity, bringing the longest-running litigation in New Zealand history to an end. India has named rivers legal entities and Bangladesh has given all its rivers legal rights.

    “Personhood status was a compromise between the government and a group of Māori tribes who demanded recognition for the river based on past treaties,” Mangrum writes. “I’m interested in how these very different kinds of discourse — political rights, environmental science, indigenous culture, public health — have come together during the 20th and 21st centuries.”

    For the chapter, Mangrum explores the argument made by legal theorist Christopher Stone in “Should Trees Have Standing?” First published in 1972, Stone’s essay is a foundational argument in environmental law. Stone maintains that natural objects can be given legal personhood, an argument that is often cited in legal framings of environmental rights. Mangrum explores the literary dimensions of legal personhood.

    “I argue that the intellectual and cultural history of legal personhood shares unacknowledged debts to the evolution in theories of literary personhood,” Mangrum writes. “A reader’s attribution of personhood does not serve the same social and moral functions as the attribution of personhood to corporations and other nonhuman entities. However, I argue that modern ideas about literary personhood are cognitively homologous with legal personhood: despite serving different functions, these conceptions of personhood share conceptual structures and intellectual origins.”

    In one recently published article, he examines the language used by Rachel Carson and others in the nascent environmental movement. In 1963, Carson testified before a U.S. Senate subcommittee on the threat of pesticides. It was considered a watershed moment for environmentalism, but notable also for intellectual history. Her use of the vocabulary of rights and her advocacy for environmental regulations in a public forum were significant forces in the institutionalization of environmental rights.

    Mangrum notes Carson’s claim of “the right of the citizen to be secure in his own home against the intrusion of poisons applied by other persons.” Carson uses the language of rights to introduce environmental concerns within the public sphere, but this language also has implications for how we understand our relationship to the nonhuman world.

    Before arriving at MIT in 2022, Mangrum taught at the University of the South, the University of Michigan, and Davidson College. He is the author of “Land of Tomorrow: Postwar Fiction and the Crisis of American Liberalism” (Oxford 2019), which examines 20th-century literary fiction and popular philosophy to understand shifts in American liberalism after World War II. He received his PhD from the University of North Carolina at Chapel Hill. More

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    in Environment

    Greening roofs to boost climate resilience

    When the historic cities of Europe were built hundreds of years ago, there were open green spaces all around them. But today’s city centers can be a 30-minute drive or more to the vast open greenery that earlier Europeans took for granted.

    That’s what the startup Roofscapes is trying to change. The company, founded by three students from MIT’s master of architecture program, is using timber structures to turn the ubiquitous pitched roofs of Paris into accessible green spaces.

    The spaces would provide a way to grow local food, anchor biodiversity, reduce the temperatures of buildings, improve air quality, increase water retention, and give residents a new way to escape the dense urban clusters of modern times.

    “We see this as a way to unlock the possibilities of these buildings,” says Eytan Levi MA ’21, SM ’21, who co-founded the company with Olivier Faber MA ’23 and Tim Cousin MA ’23. “These surfaces weren’t being used otherwise but could actually have a highly positive contribution to the value of the buildings, the environment, and the lives of the people.”

    For the co-founders, Roofscapes is about helping build up climate resilience for the future while improving quality of life in cities now.

    “It was always important to us to work with as little contradictions to our values as possible in terms of environmental and social impact,” Faber says. “For us, Roofscapes is a way to apply some of our academic learnings to the real world in a way that is tactical and impactful, because we’re tapping into this whole issue — pitched roof adaptation — that has been ignored by traditional architecture.”

    Three architects with a vision

    The founders, who grew up in France, met while studying architecture as undergraduates in Switzerland, but after graduating and working at design firms for a few years, they began discussing other ways they could make a difference.

    “We knew we wanted to have an impact on the built environment that was different than what a lot of architectural firms were doing. We were thinking about a startup, but mostly we came to MIT because we knew we’d have a lot of agency to grow our skills and competency in adapting the built environment to the climate and biodiversity crises,” Faber explains.

    Three months after coming to MIT, they applied to the DesignX accelerator to explore ways to make cities greener by using timber structures to build flat, green platforms on the ubiquitous pitched roofs of European cities’ older buildings.

    “In European city centers, two thirds of the roofs are pitched, and there’s no solution to make them accessible and put green surfaces on them,” Cousin says. “Meanwhile, we have all these issues with heat islands and excessive heat in urban centers, among other issues like biodiversity collapse, retention of rain water, lack of green spaces. Green roofs are one of the best ways to address all of these problems.”

    They began making small models of their imagined green roofs and talking with structural engineers around campus. The founders also gained operational knowledge from MIT’s Center for Real Estate, where Levi studied.

    In 2021, they showcased a 170-square-foot model at the Seoul Biennale of Architecture and Urbanism in South Korea. The model showed roofs made from different materials and pitched at different angles, along with versions of Roofscapes’ wooden platforms with gardens and vegetation built on top.

    When Levi graduated, he moved to Paris, where Cousin and Faber are joining him this spring. “We’re starting with Paris because all the roofs there are the same height, and you can really feel the potential when you go up there to help the city adapt,” says Cousin.

    Roofscapes’ big break came last year, when the company won a grant from the City of Paris as part of a program to improve the city’s climate resilience. The grant will go toward Roofscapes’ first project on the roof of a former town hall building in the heart of Paris. The company plans to test the project’s impact on the temperature of the buildings, humidity levels, and the biodiversity it can foster.

    “We were just three architects with a vision, and at MIT it became a company, and now in Paris we’re seeing the reality of deploying this vision,” Cousin says. “This is not something you do with three people. You need everyone in the city on the same side. We’re being advocates, and it’s exciting to be in this position.”

    A grassroots roof movement

    The founders say they hear at least once a week from a building owner or tenant who is excited to become a partner, giving them a list of more than 60 buildings to consider for their systems down the line. Still, they plan to focus on running tests on a few pilot projects in Paris before expanding more quickly using prefabricated structures.

    “It’s great to hear that constant interest,” Levi says. “It’s like we’re on the same team, because they’re potential clients, but they’re also cheering us on in our work. We know from the interest that once we have a streamlined process, we can get a lot of projects at once.”

    Even in just the three years since founding the company, the founders say they’ve seen their work take on a new sense of urgency.

    “We’ve seen a shift in people’s minds since we started three years ago,” Levi says. “Global warming is becoming increasingly graspable, and we’re seeing a greater will from building owners and inhabitants. People are very supportive of the notion that we have a heritage environment, but as the climate changes drastically, our building stock doesn’t work anymore the way it worked in the 19th century. It needs to be adapted, and that’s what we are doing.” More