Aurelia Butler

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    in Environment

    Harnessing synthetic biology to make sustainable alternatives to petroleum products

    Reducing our reliance on fossil fuels is going to require a transformation in the way we make things. That’s because the hydrocarbons found in fuels like crude oil, natural gas, and coal are also in everyday items like plastics, clothing, and cosmetics.

    Now Visolis, founded by Deepak Dugar SM ’11, MBA ’13, PhD ’13, is combining synthetic biology with chemical catalysis to reinvent the way the world makes things — and reducing gigatons of greenhouse gas emissions in the process.

    The company — which uses a microbe to ferment biomass waste like wood chips and create a molecular building block called mevalonic acid — is more sustainably producing everything from car tires and cosmetics to aviation fuels by tweaking the chemical processes involved to make different byproducts.

    “We started with [the rubber component] isoprene as the main molecule we produce [from mevalonic acid], but we’ve expanded our platform with this unique combination of chemistry and biology that allows us to decarbonize multiple supply chains very rapidly and efficiently,” Dugar explains. “Imagine carbon-negative yoga pants. We can make that happen. Tires can be carbon-negative, personal care can lower its footprint — and we’re already selling into personal care. So in everything from personal care to apparel to industrial goods, our platform is enabling decarbonization of manufacturing.”

    “Carbon-negative” is a term Dugar uses a lot. Visolis has already partnered with some of the world’s largest consumers of isoprene, a precursor to rubber, and now Dugar wants to prove out the company’s process in other emissions-intensive industries.

    “Our process is carbon-negative because plants are taking CO2 from the air, and we take that plant matter and process it into something structural, like synthetic rubber, which is used for things like roofing, tires, and other applications,” Dugar explains. “Generally speaking, most of that material at the end of its life gets recycled, for example to tarmac or road, or, worst-case scenario, it ends up in a landfill, so the CO2 that was captured by the plant matter stays captured in the materials. That means our production can be carbon-negative depending on the emissions of the production process. That allows us to not only reduce climate change but start reversing it. That was an insight I had about 10 years ago at MIT.”

    Finding a path

    For his PhD, Dugar explored the economics of using microbes to make high-octane gas additives. He also took classes at the MIT Sloan School of Management on sustainability and entrepreneurship, including the particularly influential course 15.366 (Climate and Energy Ventures). The experience inspired him to start a company.

    “I wanted to work on something that could have the largest climate impact, and that was replacing petroleum,” Dugar says. “It was about replacing petroleum not just as a fuel but as a material as well. Everything from the clothes we wear to the furniture we sit on is often made using petroleum.”

    By analyzing recent advances in synthetic biology and making some calculations from first principles, Dugar decided that a microbial approach to cleaning up the production of rubber was viable. He participated in the MIT Clean Energy Prize and worked with others at MIT to prove out the idea. But it was still just an idea. After graduation, he took a consulting job at a large company, spending his nights and weekends renting lab space to continue trying to make his sustainable rubber a reality.

    After 18 months, by applying engineering concepts like design-for-scale to synthetic biology, Dugar was able to develop a microbe that met 80 percent of his criteria for making an intermediate molecule called mevalonic acid. From there, he developed a chemical catalysis process that converted mevalonic acid to isoprene, the main component of natural rubber. Visolis has since patented other chemical conversion processes that turn mevalonic acid to aviation fuel, polymers, and fabrics.

    Dugar left his consulting job in 2014 and was awarded a fellowship to work on Visolis full-time at the Lawrence Berkeley National Lab via Activate, an incubator empowering scientists to reinvent the world.

    From rubber to jet fuels

    Today, in addition to isoprene, Visolis is selling skin care products through the brand Ameva Bio, which produces mevalonic acid-based creams by recycling plant byproducts created in other processes. The company offers refillable bottles and even offsets emissions from the shipping of its products.

    “We are working throughout the supply chain,” Dugar says. “It made sense to clean up the isoprene part of the rubber supply chain rather than the entire supply chain. But we’re also producing molecules for skin that are better for you, so you can put something much more sustainable and healthier on your body instead of petrochemicals. We launched Ameva to demonstrate that brands can leverage synthetic biology to turn carbon-negative ingredients into high-performing products.”

    Visolis is also starting the process of gaining regulatory approval for its sustainable aviation fuel, which Dugar believes could have the biggest climate impact of any of the company’s products by cleaning up the production of fuels for commercial flight.

    “We’re working with leading companies to help them decarbonize aviation” Dugar says. “If you look at the lifecycle of fuel, the current petroleum-based approach is we dig out hydrocarbons from the ground and burn it, emitting CO2 into the air. In our process, we take plant matter, which affixes to CO2 and captures renewable energy in those bonds, and then we transfer that into aviation fuel plus things like synthetic rubber, yoga pants, and other things that continue to hold the carbon. So, our factories can still operate at net zero carbon emissions.”

    Visolis is already generating millions of dollars in revenue, and Dugar says his goal is to scale the company rapidly now that its platform molecule has been validated.

    “We have been scaling our technology by 10 times every two to three years and are now looking to increase deployment of our technology at the same pace, which is very exciting.” Dugar says. “If you extrapolate that, very quickly you get to massive impact. That’s our goal.” More

  • 125 Shares169 Views

    in Security

    System tracks movement of food through global humanitarian supply chain

    Although more than enough food is produced to feed everyone in the world, as many as 828 million people face hunger today. Poverty, social inequity, climate change, natural disasters, and political conflicts all contribute to inhibiting access to food. For decades, the U.S. Agency for International Development (USAID) Bureau for Humanitarian Assistance (BHA) has been a leader in global food assistance, supplying millions of metric tons of food to recipients worldwide. Alleviating hunger — and the conflict and instability hunger causes — is critical to U.S. national security.

    But BHA is only one player within a large, complex supply chain in which food gets handed off between more than 100 partner organizations before reaching its final destination. Traditionally, the movement of food through the supply chain has been a black-box operation, with stakeholders largely out of the loop about what happens to the food once it leaves their custody. This lack of direct visibility into operations is due to siloed data repositories, insufficient data sharing among stakeholders, and different data formats that operators must manually sort through and standardize. As a result, accurate, real-time information — such as where food shipments are at any given time, which shipments are affected by delays or food recalls, and when shipments have arrived at their final destination — is lacking. A centralized system capable of tracing food along its entire journey, from manufacture through delivery, would enable a more effective humanitarian response to food-aid needs.

    In 2020, a team from MIT Lincoln Laboratory began engaging with BHA to create an intelligent dashboard for their supply-chain operations. This dashboard brings together the expansive food-aid datasets from BHA’s existing systems into a single platform, with tools for visualizing and analyzing the data. When the team started developing the dashboard, they quickly realized the need for considerably more data than BHA had access to.

    “That’s where traceability comes in, with each handoff partner contributing key pieces of information as food moves through the supply chain,” explains Megan Richardson, a researcher in the laboratory’s Humanitarian Assistance and Disaster Relief Systems Group.

    Richardson and the rest of the team have been working with BHA and their partners to scope, build, and implement such an end-to-end traceability system. This system consists of serialized, unique identifiers (IDs) — akin to fingerprints — that are assigned to individual food items at the time they are produced. These individual IDs remain linked to items as they are aggregated along the supply chain, first domestically and then internationally. For example, individually tagged cans of vegetable oil get packaged into cartons; cartons are placed onto pallets and transported via railway and truck to warehouses; pallets are loaded onto shipping containers at U.S. ports; and pallets are unloaded and cartons are unpackaged overseas.

    With a trace

    Today, visibility at the single-item level doesn’t exist. Most suppliers mark pallets with a lot number (a lot is a batch of items produced in the same run), but this is for internal purposes (i.e., to track issues stemming back to their production supply, like over-enriched ingredients or machinery malfunction), not data sharing. So, organizations know which supplier lot a pallet and carton are associated with, but they can’t track the unique history of an individual carton or item within that pallet. As the lots move further downstream toward their final destination, they are often mixed with lots from other productions, and possibly other commodity types altogether, because of space constraints. On the international side, such mixing and the lack of granularity make it difficult to quickly pull commodities out of the supply chain if food safety concerns arise. Current response times can span several months.

    “Commodities are grouped differently at different stages of the supply chain, so it is logical to track them in those groupings where needed,” Richardson says. “Our item-level granularity serves as a form of Rosetta Stone to enable stakeholders to efficiently communicate throughout these stages. We’re trying to enable a way to track not only the movement of commodities, including through their lot information, but also any problems arising independent of lot, like exposure to high humidity levels in a warehouse. Right now, we have no way to associate commodities with histories that may have resulted in an issue.”

    “You can now track your checked luggage across the world and the fish on your dinner plate,” adds Brice MacLaren, also a researcher in the laboratory’s Humanitarian Assistance and Disaster Relief Systems Group. “So, this technology isn’t new, but it’s new to BHA as they evolve their methodology for commodity tracing. The traceability system needs to be versatile, working across a wide variety of operators who take custody of the commodity along the supply chain and fitting into their existing best practices.”

    As food products make their way through the supply chain, operators at each receiving point would be able to scan these IDs via a Lincoln Laboratory-developed mobile application (app) to indicate a product’s current location and transaction status — for example, that it is en route on a particular shipping container or stored in a certain warehouse. This information would get uploaded to a secure traceability server. By scanning a product, operators would also see its history up until that point.   

    Hitting the mark

    At the laboratory, the team tested the feasibility of their traceability technology, exploring different ways to mark and scan items. In their testing, they considered barcodes and radio-frequency identification (RFID) tags and handheld and fixed scanners. Their analysis revealed 2D barcodes (specifically data matrices) and smartphone-based scanners were the most feasible options in terms of how the technology works and how it fits into existing operations and infrastructure.

    “We needed to come up with a solution that would be practical and sustainable in the field,” MacLaren says. “While scanners can automatically read any RFID tags in close proximity as someone is walking by, they can’t discriminate exactly where the tags are coming from. RFID is expensive, and it’s hard to read commodities in bulk. On the other hand, a phone can scan a barcode on a particular box and tell you that code goes with that box. The challenge then becomes figuring out how to present the codes for people to easily scan without significantly interrupting their usual processes for handling and moving commodities.” 

    As the team learned from partner representatives in Kenya and Djibouti, offloading at the ports is a chaotic, fast operation. At manual warehouses, porters fling bags over their shoulders or stack cartons atop their heads any which way they can and run them to a drop point; at bagging terminals, commodities come down a conveyor belt and land this way or that way. With this variability comes several questions: How many barcodes do you need on an item? Where should they be placed? What size should they be? What will they cost? The laboratory team is considering these questions, keeping in mind that the answers will vary depending on the type of commodity; vegetable oil cartons will have different specifications than, say, 50-kilogram bags of wheat or peas.

    Leaving a mark

    Leveraging results from their testing and insights from international partners, the team has been running a traceability pilot evaluating how their proposed system meshes with real-world domestic and international operations. The current pilot features a domestic component in Houston, Texas, and an international component in Ethiopia, and focuses on tracking individual cartons of vegetable oil and identifying damaged cans. The Ethiopian team with Catholic Relief Services recently received a container filled with pallets of uniquely barcoded cartons of vegetable oil cans (in the next pilot, the cans will be barcoded, too). They are now scanning items and collecting data on product damage by using smartphones with the laboratory-developed mobile traceability app on which they were trained. 

    “The partners in Ethiopia are comparing a couple lid types to determine whether some are more resilient than others,” Richardson says. “With the app — which is designed to scan commodities, collect transaction data, and keep history — the partners can take pictures of damaged cans and see if a trend with the lid type emerges.”

    Next, the team will run a series of pilots with the World Food Program (WFP), the world’s largest humanitarian organization. The first pilot will focus on data connectivity and interoperability, and the team will engage with suppliers to directly print barcodes on individual commodities instead of applying barcode labels to packaging, as they did in the initial feasibility testing. The WFP will provide input on which of their operations are best suited for testing the traceability system, considering factors like the network bandwidth of WFP staff and local partners, the commodity types being distributed, and the country context for scanning. The BHA will likely also prioritize locations for system testing.

    “Our goal is to provide an infrastructure to enable as close to real-time data exchange as possible between all parties, given intermittent power and connectivity in these environments,” MacLaren says.

    In subsequent pilots, the team will try to integrate their approach with existing systems that partners rely on for tracking procurements, inventory, and movement of commodities under their custody so that this information is automatically pushed to the traceability server. The team also hopes to add a capability for real-time alerting of statuses, like the departure and arrival of commodities at a port or the exposure of unclaimed commodities to the elements. Real-time alerts would enable stakeholders to more efficiently respond to food-safety events. Currently, partners are forced to take a conservative approach, pulling out more commodities from the supply chain than are actually suspect, to reduce risk of harm. Both BHA and WHP are interested in testing out a food-safety event during one of the pilots to see how the traceability system works in enabling rapid communication response.

    To implement this technology at scale will require some standardization for marking different commodity types as well as give and take among the partners on best practices for handling commodities. It will also require an understanding of country regulations and partner interactions with subcontractors, government entities, and other stakeholders.

    “Within several years, I think it’s possible for BHA to use our system to mark and trace all their food procured in the United States and sent internationally,” MacLaren says.

    Once collected, the trove of traceability data could be harnessed for other purposes, among them analyzing historical trends, predicting future demand, and assessing the carbon footprint of commodity transport. In the future, a similar traceability system could scale for nonfood items, including medical supplies distributed to disaster victims, resources like generators and water trucks localized in emergency-response scenarios, and vaccines administered during pandemics. Several groups at the laboratory are also interested in such a system to track items such as tools deployed in space or equipment people carry through different operational environments.

    “When we first started this program, colleagues were asking why the laboratory was involved in simple tasks like making a dashboard, marking items with barcodes, and using hand scanners,” MacLaren says. “Our impact here isn’t about the technology; it’s about providing a strategy for coordinated food-aid response and successfully implementing that strategy. Most importantly, it’s about people getting fed.” More

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    in Environment

    Study: The ocean’s color is changing as a consequence of climate change

    The ocean’s color has changed significantly over the last 20 years, and the global trend is likely a consequence of human-induced climate change, report scientists at MIT, the National Oceanography Center in the U.K., and elsewhere.  

    In a study appearing today in Nature, the team writes that they have detected changes in ocean color over the past two decades that cannot be explained by natural, year-to-year variability alone. These color shifts, though subtle to the human eye, have occurred over 56 percent of the world’s oceans — an expanse that is larger than the total land area on Earth.

    In particular, the researchers found that tropical ocean regions near the equator have become steadily greener over time. The shift in ocean color indicates that ecosystems within the surface ocean must also be changing, as the color of the ocean is a literal reflection of the organisms and materials in its waters.

    At this point, the researchers cannot say how exactly marine ecosystems are changing to reflect the shifting color. But they are pretty sure of one thing: Human-induced climate change is likely the driver.

    “I’ve been running simulations that have been telling me for years that these changes in ocean color are going to happen,” says study co-author Stephanie Dutkiewicz, senior research scientist in MIT’s Department of Earth, Atmospheric and Planetary Sciences and the Center for Global Change Science. “To actually see it happening for real is not surprising, but frightening. And these changes are consistent with man-induced changes to our climate.”

    “This gives additional evidence of how human activities are affecting life on Earth over a huge spatial extent,” adds lead author B. B. Cael PhD ’19 of the National Oceanography Center in Southampton, U.K. “It’s another way that humans are affecting the biosphere.”

    The study’s co-authors also include Stephanie Henson of the National Oceanography Center, Kelsey Bisson at Oregon State University, and Emmanuel Boss of the University of Maine.

    Above the noise

    The ocean’s color is a visual product of whatever lies within its upper layers. Generally, waters that are deep blue reflect very little life, whereas greener waters indicate the presence of ecosystems, and mainly phytoplankton — plant-like microbes that are abundant in upper ocean and that contain the green pigment chlorophyll. The pigment helps plankton harvest sunlight, which they use to capture carbon dioxide from the atmosphere and convert it into sugars.

    Phytoplankton are the foundation of the marine food web that sustains progressively more complex organisms, on up to krill, fish, and seabirds and marine mammals. Phytoplankton are also a powerful muscle in the ocean’s ability to capture and store carbon dioxide. Scientists are therefore keen to monitor phytoplankton across the surface oceans and to see how these essential communities might respond to climate change. To do so, scientists have tracked changes in chlorophyll, based on the ratio of how much blue versus green light is reflected from the ocean surface, which can be monitored from space

    But around a decade ago, Henson, who is a co-author of the current study, published a paper with others, which showed that, if scientists were tracking chlorophyll alone, it would take at least 30 years of continuous monitoring to detect any trend that was driven specifically by climate change. The reason, the team argued, was that the large, natural variations in chlorophyll from year to year would overwhelm any anthropogenic influence on chlorophyll concentrations. It would therefore take several decades to pick out a meaningful, climate-change-driven signal amid the normal noise.

    In 2019, Dutkiewicz and her colleagues published a separate paper, showing through a new model that the natural variation in other ocean colors is much smaller compared to that of chlorophyll. Therefore, any signal of climate-change-driven changes should be easier to detect over the smaller, normal variations of other ocean colors. They predicted that such changes should be apparent within 20, rather than 30 years of monitoring.

    “So I thought, doesn’t it make sense to look for a trend in all these other colors, rather than in chlorophyll alone?” Cael says. “It’s worth looking at the whole spectrum, rather than just trying to estimate one number from bits of the spectrum.”

     The power of seven

    In the current study, Cael and the team analyzed measurements of ocean color taken by the Moderate Resolution Imaging Spectroradiometer (MODIS) aboard the Aqua satellite, which has been monitoring ocean color for 21 years. MODIS takes measurements in seven visible wavelengths, including the two colors researchers traditionally use to estimate chlorophyll.

    The differences in color that the satellite picks up are too subtle for human eyes to differentiate. Much of the ocean appears blue to our eye, whereas the true color may contain a mix of subtler wavelengths, from blue to green and even red.

    Cael carried out a statistical analysis using all seven ocean colors measured by the satellite from 2002 to 2022 together. He first looked at how much the seven colors changed from region to region during a given year, which gave him an idea of their natural variations. He then zoomed out to see how these annual variations in ocean color changed over a longer stretch of two decades. This analysis turned up a clear trend, above the normal year-to-year variability.

    To see whether this trend is related to climate change, he then looked to Dutkiewicz’s model from 2019. This model simulated the Earth’s oceans under two scenarios: one with the addition of greenhouse gases, and the other without it. The greenhouse-gas model predicted that a significant trend should show up within 20 years and that this trend should cause changes to ocean color in about 50 percent of the world’s surface oceans — almost exactly what Cael found in his analysis of real-world satellite data.

    “This suggests that the trends we observe are not a random variation in the Earth system,” Cael says. “This is consistent with anthropogenic climate change.”

    The team’s results show that monitoring ocean colors beyond chlorophyll could give scientists a clearer, faster way to detect climate-change-driven changes to marine ecosystems.

    “The color of the oceans has changed,” Dutkiewicz says. “And we can’t say how. But we can say that changes in color reflect changes in plankton communities, that will impact everything that feeds on plankton. It will also change how much the ocean will take up carbon, because different types of plankton have different abilities to do that. So, we hope people take this seriously. It’s not only models that are predicting these changes will happen. We can now see it happening, and the ocean is changing.”

    This research was supported, in part, by NASA. More

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    in Environment

    Studying rivers from worlds away

    Rivers have flowed on two other worlds in the solar system besides Earth: Mars, where dry tracks and craters are all that’s left of ancient rivers and lakes, and Titan, Saturn’s largest moon, where rivers of liquid methane still flow today.

    A new technique developed by MIT geologists allows scientists to see how intensely rivers used to flow on Mars, and how they currently flow on Titan. The method uses satellite observations to estimate the rate at which rivers move fluid and sediment downstream.

    Applying their new technique, the MIT team calculated how fast and deep rivers were in certain regions on Mars more than 1 billion years ago. They also made similar estimates for currently active rivers on Titan, even though the moon’s thick atmosphere and distance from Earth make it harder to explore, with far fewer available images of its surface than those of Mars.

    “What’s exciting about Titan is that it’s active. With this technique, we have a method to make real predictions for a place where we won’t get more data for a long time,” says Taylor Perron, the Cecil and Ida Green Professor in MIT’s Department of Earth, Atmospheric and Planetary Sciences (EAPS). “And on Mars, it gives us a time machine, to take the rivers that are dead now and get a sense of what they were like when they were actively flowing.”

    Perron and his colleagues have published their results today in the Proceedings of the National Academy of Sciences. Perron’s MIT co-authors are first author Samuel Birch, Paul Corlies, and Jason Soderblom, with Rose Palermo and Andrew Ashton of the Woods Hole Oceanographic Institution (WHOI), Gary Parker of the University of Illinois at Urbana-Champaign, and collaborators from the University of California at Los Angeles, Yale University, and Cornell University.

    River math

    The team’s study grew out of Perron and Birch’s puzzlement over Titan’s rivers. The images taken by NASA’s Cassini spacecraft have shown a curious lack of fan-shaped deltas at the mouths of most of the moon’s rivers, contrary to many rivers on Earth. Could it be that Titan’s rivers don’t carry enough flow or sediment to build deltas?

    The group built on the work of co-author Gary Parker, who in the 2000s developed a series of mathematical equations to describe river flow on Earth. Parker had studied measurements of rivers taken directly in the field by others. From these data, he found there were certain universal relationships between a river’s physical dimensions — its width, depth, and slope — and the rate at which it flowed. He drew up equations to describe these relationships mathematically, accounting for other variables such as the gravitational field acting on the river, and the size and density of the sediment being pushed along a river’s bed.

    “This means that rivers with different gravity and materials should follow similar relationships,” Perron says. “That opened up a possibility to apply this to other planets too.”

    Getting a glimpse

    On Earth, geologists can make field measurements of a river’s width, slope, and average sediment size, all of which can be fed into Parker’s equations to accurately predict a river’s flow rate, or how much water and sediment it can move downstream. But for rivers on other planets, measurements are more limited, and largely based on images and elevation measurements collected by remote satellites. For Mars, multiple orbiters have taken high-resolution images of the planet. For Titan, views are few and far between.

    Birch realized that any estimate of river flow on Mars or Titan would have to be based on the few characteristics that can be measured from remote images and topography — namely, a river’s width and slope. With some algebraic tinkering, he adapted Parker’s equations to work only with width and slope inputs. He then assembled data from 491 rivers on Earth, tested the modified equations on these rivers, and found that the predictions based solely on each river’s width and slope were accurate.

    Then, he applied the equations to Mars, and specifically, to the ancient rivers leading into Gale and Jezero Craters, both of which are thought to have been water-filled lakes billions of years ago. To predict the flow rate of each river, he plugged into the equations Mars’ gravity, and estimates of each river’s width and slope, based on images and elevation measurements taken by orbiting satellites.

    From their predictions of flow rate, the team found that rivers likely flowed for at least 100,000 years at Gale Crater and at least 1 million years at Jezero Crater — long enough to have possibly supported life. They were also able to compare their predictions of the average size of sediment on each river’s bed with actual field measurements of Martian grains near each river, taken by NASA’s Curiosity and Perseverance rovers. These few field measurements allowed the team to check that their equations, applied on Mars, were accurate.

    The team then took their approach to Titan. They zeroed in on two locations where river slopes can be measured, including a river that flows into a lake the size of Lake Ontario. This river appears to form a delta as it feeds into the lake. However, the delta is one of only a few thought to exist on the moon — nearly every viewable river flowing into a lake mysteriously lacks a delta. The team also applied their method to one of these other delta-less rivers.

    They calculated both rivers’ flow and found that they may be comparable to some of the biggest rivers on Earth, with deltas estimated to have a flow rate as large as the Mississippi. Both rivers should move enough sediment to build up deltas. Yet, most rivers on Titan lack the fan-shaped deposits. Something else must be at work to explain this lack of river deposits.

    In another finding, the team calculated that rivers on Titan should be wider and have a gentler slope than rivers carrying the same flow on Earth or Mars. “Titan is the most Earth-like place,” Birch says. ”We’ve only gotten a glimpse of it. There’s so much more that we know is down there, and this remote technique is pushing us a little closer.”

    This research was supported, in part, by NASA and the Heising-Simons Foundation. More

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    in Environment

    Andrea Lo ’21 draws on ecological lessons for life, work, and education

    Growing up in Los Angeles about 10 minutes away from the Ballona Wetlands, Andrea Lo ’21 has long been interested in ecology. She witnessed, in real-time, the effects of urbanization and the impacts that development had on the wetlands. 

    “In hindsight, it really helped shape my need for a career — and a life — where I can help improve my community and the environment,” she says.

    Lo, who majored in biology at MIT, says a recurring theme in her life has been the pursuit of balance, valuing both extracurricular and curricular activities. She always felt an equal pull toward STEM and the humanities, toward wet lab work and field work, and toward doing research and helping her community. 

    “One of the most important things I learned in 7.30[J] (Fundamentals of Ecology) was that there are always going to be trade-offs. That’s just the way of life,” she says. “The biology major at MIT is really flexible. I got a lot of room to explore what I was interested in and get a good balance overall, with humanities classes along with technical classes.” 

    Lo was drawn to MIT because of the focus on hands-on work — but many of the activities Lo was hoping to do, both extracurricular and curricular, were cut short because of the pandemic, including her lab-based Undergraduate Research Opportunities Program (UROP) project. 

    Instead, she pursued a UROP with MIT Sea Grant, working on a project in partnership with Northeastern University and the Charles River Conservancy with funding support from the MIT Community Service fund as part of STEAM Saturday.  

    She was involved in creating Floating Wetland kits, an educational activity directed at students in grades 4 to 6 to help students understand ecological concepts,the challenges the Charles River faces due to urbanization, and how floating wetlands improve the ecosystem. 

    “Our hope was to educate future generations of local students in Cambridge in order for them to understand the ecology surrounding where they live,” she says. 

    In recent years, many bodies of water in Massachusetts have become unusable during the warmer months due to the process of eutrophication: stormwater runoff picks up everything — from fertilizer and silt to animal excrement — and deposits it at the lowest point, which is often a body of water. This leads to an excess of nutrients in the body of water and, when combined with warm temperatures, can lead to harmful algal blooms, making the water sludgy, bright green, and dangerously toxic. 

    The wetland kits Lo worked with were mini ecosystems, replicating a full-sized floating wetland. One such floating wetland can be seen from the Longfellow Bridge at one end of MIT’s campus — the Charles River floating wetland is a patch of grass attached to a buoy like a boat, which is often visited by birds and inhabited by much smaller critters that cannot be seen from the shore.  

    The Charles River floating wetland has a variety of flora, but the kits Lo helped present use only wheat grass because it is easy to grow and has long, dangling roots that could penetrate the watery medium below. A water tray beneath the grass — the Charles river of the mini ecosystem — contains spirulina powder for replicating algae growth and daphnia, which are small, planktonic crustaceans that help keep freshwater clean and usable. 

    “This work was really fulfilling, but it’s also really important, because environmental sustainability relies on future generations to carry on the work that past generations have been doing,” she says. “MIT’s motto is ‘mens et manus’ — education for practical application, and applying theoretical knowledge to what we do in our daily lives. I think this project really helped reinforce that.” 

    Since 2021, Lo has been working in Denmark in a position she learned about through the MIT-Denmark program. 

    She chose Denmark because of its reputation for environmental and sustainability issues and because she didn’t know much about it except for it being one of the happiest countries in the world, often thought of synonymously with the word “hygge,” which has no direct translation but encapsulates coziness and comfort from the small joys in life. 

    “At MIT, we have a very strong work-hard, play-hard culture. I think we can learn a lot from the work-life balance that Denmark has a reputation for,” she says. “I really wanted to take the opportunity in between graduation and whatever came after to explore beyond my bubble. For me, it was important to step back, out of my comfort zone, step into a different environment — and just live.”

    Currently, her personal project is comparing the conditions of two lagoons on the island of Fyn in Denmark. Both are naturally occurring, but in different states of environmental health. 

    She’s been doing a mix of field work and lab work. She collects sediment and fauna samples using a steel corer, or “butter stick” in her lab’s slang. In the same way that one can use a metal tube-shaped tool to remove the core of an apple, she punches the steel corer into the ground, removing a plug of sample. She then sifts the sample through 1 millimeter mesh, preserves the filtered sample in formalin, and takes everything back to the lab. 

    Once there, she looks through the sample to find macrofauna — mollusks, barnacles, and polychaetes, a bristly-looking segmented worm, for example. Collected over time, sediment characteristics like organic matter content, sediment grain size, and the size and abundance of macrofauna, can reveal trends that can help determine the health of the ecosystem. 

    Lo doesn’t have any concrete results yet, but her data could help researchers project the recovery of a lagoon that was rehabilitated using a technique called managed realignment, where water is allowed to reclaim areas where it was once found. She says she’s glad she gets a mix of field work and lab work, even on Denmark’s stormiest days. 

    “Sometimes there are really cold days where it’s windy and I wish I was in the lab, but, at the same time, it’s nice to have a balance where I can be outside and really be hands-on with my work,” she says.  

    Reflecting her dual interests in the technical and the innovative, she will be back in the Greater Boston area in the fall, pursuing a master of science in innovation and management and an MS in civil and environmental engineering at the Tufts Gordon Institute.

    “So much has happened and changed due to the pandemic that it’s easy to dwell on what could’ve been, but I tell myself to be optimistic and take the positive aspects that have come out of the circumstances,” Lo says. “My opportunities with the Sea Grant, MISTI, and Tufts definitely wouldn’t have happened if the pandemic hadn’t happened.” More

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    Transatlantic connections make the difference for MIT Portugal

    Successful relationships take time to develop, with both parties investing energy and resources and fostering mutual trust and understanding. The MIT Portugal Program (MPP), a strategic partnership between MIT, Portuguese universities and research institutions, and the Portuguese government, is a case in point.

    Portugal’s inaugural partnership with a U.S. university, MPP was established in 2006 as a collaboration between MIT and the Portuguese Science and Technology Foundation (Fundação para a Ciência e Tecnologia, or FCT). Since then, the program has developed research platforms in areas such as bioengineering, sustainable energy, transportation systems, engineering design, and advanced manufacturing. Now halfway through its third phase (MPP2030, begun in 2018), the program owes much of its success to the bonds connecting institutions and people across the Atlantic over the past 17 years.

    “When you look at the successes and the impact, these things don’t happen overnight,” says John Hansman, the T. Wilson Professor of Aeronautics and Astronautics at MIT and co-director of MPP, noting, in particular, MPP’s achievements in the areas of energy and ocean research, as well as bioengineering. “This has been a longstanding relationship that we have and want to continue. I think it’s been beneficial to Portugal and to MIT. I think you can argue it has made substantial contributions to the success that Portugal is currently experiencing both in its technical capabilities and also its energy policy.”

    With research often aimed at climate and sustainability solutions, one of MPP’s key strengths is its education of future leaders in science, technology, and entrepreneurship. And the program’s impacts carry forward, as several former MPP students are now on the faculty at participating Portuguese universities.

    “The original intent of working together with Portugal was to try to establish collaboration between universities and to instill some of the MIT culture with the culture in Portugal, and I think that’s been hugely successful,” says Douglas Hart, MPP co-director and professor of mechanical engineering at MIT. “It has had a lot of impacts in terms of the research, but also the people.”

    One of those people is André Pina, associate director of H2 strategy and origination at the company EDP, who was in residence at MIT in 2014 as part of the MPP Sustainable Energy Systems Doctoral Program. He says the competencies and experiences he acquired have been critical to his professional development in energy system planning, have influenced his approach to problem solving, and have allowed him to bring “holistic thinking” to business endeavors.

    “The MIT Portugal Program has created a collaborative ecosystem between Portuguese universities, companies, and MIT that enabled the training of highly qualified professionals, while contributing to the positioning of Portuguese companies in new cutting-edge fields,” he says.

    Building on MPP’s previous successes, MPP2030 focuses on advancing research in four strategic areas: climate science and climate change; earth systems from oceans to near space; digital transformation in manufacturing; and sustainable cities — all involving data science-intensive approaches and methodologies. Within these broad scientific areas, FCT funding has enabled seven collaborative large-scale “flagship” projects between Portuguese and MIT researchers during the current phase, as well as dozens of smaller projects.

    Flagship projects currently underway include:

    ·   AEROS Constellation

    ·   C-Tech: Climate Driven Technologies for Low Carbon Cities

    ·   K2D: Knowledge and Data from the Deep to Space

    ·   NEWSAT

    ·   Operator: Digital Transformation in Industry with a Focus on the Operator 4.0

    ·   SNOB-5G: Scalable Network Backhauling for 5G

    ·   Transformer 4.0: Digital Revolution of Power Transformers

    Sustainability plays a significant role in MPP — reflective of the value both Portugal and MIT place on environmental, energy, and climate solutions. Projects under the Sustainable Cities strategic area, for example, are “helping cities in Portugal to become more efficient and more sustainable,” Hansman says, noting that MPP’s influence is being felt in cities across the country and it is “having a big impact in terms of local city planning activities.”

    Regarding energy, Hansman points to a previous MPP phase that focused on the Azores as an isolated energy ecosystem and investigated its ability to minimize energy use and become energy independent.

    “That view of system-level energy use helped to stimulate activity on the mainland in Portugal, which has helped Portugal become a leader in various energy sources and made them less vulnerable in the last year or two,” Hansman says.

    In the Oceans to Near Space strategic area, the K2D flagship project also emphasizes research into sustainability solutions, as well as resilience to environmental change. Over the past few years, K2D researchers in Portugal and MIT have worked together to develop components that permit cost-effective gathering of chemical, physical, biological, and environmental data from the ocean depths. One current project investigates the integration of autonomous underwater vehicles with subsea cables to enhance both environmental monitoring and hazard warning systems.

    “The program has been very successful,” Hart says. “They are now deploying a 2-kilometer cable just south of Lisbon, which will be in place in another month or so. Portugal has been hit with tsunamis that caused tremendous devastation, and one of the objectives of these cables is to sense tsunamis. So, it’s an early warning system.”

    As a leader in ocean technology with a long history of maritime discovery, Portugal provides many opportunities for MIT’s ocean researchers. Hart notes that the Portuguese military invites international researchers on board its ships, providing MIT with research opportunities that would be financially difficult otherwise.

    Hansman adds that partnering with researchers in the Azores provides MIT with unique access to facilities and labs in the middle of the Atlantic Ocean. For example, Hart will be teaching at a marine robotics summer school in the Azores this July.

    Cadence Payne, an MIT PhD candidate, is among those planning to attend. Through MPP’s AEROS project, Payne has helped develop a modular “cubesat” that will orbit over Portugal’s Exclusive Economic Zone collecting images and radio data to help define the ecological health of the country’s coastal waters. The nanosatellite is expected to launch in late 2023 or early 2024, says Payne, adding that it will be Portugal’s first cubesat mission.

    “In monitoring the ocean, you’re monitoring the climate,” Payne says. “If you want to do work on detecting climate change and developing methods of mitigating climate change … it helps to integrate international collaboration,” she says, adding that, for students, “it’s been a really beautiful opportunity for us to see the benefits of collaboration.”

    “I would say one of the main benefits of working with Portugal is that we share many interests in research in the sense that they’re very interested in climate change, sustainability, environmental impacts and those kinds of things,” says Hart. “They have turned out to be a very good strategic partner for MIT, and, hopefully, MIT for them.” More

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    MIT climate and sustainability interns consider aviation emissions and climate change

    Over 600 MIT students are traveling abroad with the MIT International Science and Technology Initiatives (MISTI) to intern, research, and work in organizations across 25 countries this summer. Twenty percent of the students were placed in areas related to climate and sustainability.

    Through MISTI, hundreds of MIT students travel abroad each summer to intern in companies, universities, governments, and nongovernmental organizations. Since 2018, around 20 percent of the internships and research experiences have been in areas related to climate and sustainability. MISTI has been working to increase the number of interns working on these projects by increasing the number of hosts and available grants, as well as connecting with other labs, departments, and centers across MIT to support students’ global experiences.

    For the first time this year, MISTI developed pre-departure sessions intended to help students reflect on their experiences in the wider context of sustainability and climate change. Around 90 students were invited to participate in a Canvas course and an in-person session with guest speakers. In the Canvas session, students were asked to calculate the carbon footprint of their flight to their MISTI destination and compare the results to other common daily activities. Four out of five of them expressed that the level of emissions from their flights was higher, or much higher, than they previously thought. Half of the students expressed that this was the first time they thought about their flight emissions for the summer. The students were then directed to the MIT Climate Portal website and asked to reflect on the impact of carbon dioxide emissions on the climate and the effects of climate change on economically developing countries. The Canvas exercise concluded with readings and reflections on what can be done to address the climate crisis.

    The in-person session featured David Hsu, associate professor of urban and environmental planning and co-chair of the Campus Fast Forward working group on climate education, who presented his research and work on flight emissions. He emphasized the high impact of aviation on carbon dioxide emissions and how emissions are unevenly distributed on a global scale, based on income levels and per capita bases. A small group of travelers account for most of the emissions, which is also true in academic settings where a small number of travelers have a much higher carbon footprint. Hsu also explained the School of Architecture and Planning climate action plan and how it addresses faculty and student travel. “I know it’s hard. If we at MIT want to be leaders in this area, talking about it is not enough,” he said. “We have to act. We cannot be models just by doing research; we have to be role models at all levels. Faculty, staff, and students have to change their flight habits.”

    Having completed the climate and sustainability training, Favianna Colón Irizarry, a rising second-year majoring in chemical and biological engineering, explains, “to minimize our carbon footprint, we are taught to eat consciously and use environmentally friendly products. What we are not taught is that this alone will not make a difference; we ought to sacrifice more, like flying selectively and meaningfully, to truly make an impact. MISTI’s Climate and Sustainability helped me recognize this, as well as prepare me for how I choose to proceed in my future green endeavors.”

    Also during the session, rising seniors Anushree Chaudhuri and Melissa Stok, the leads for the MIT Student Sustainability Coalition, presented their work around coordinating efforts among students and the vast landscape of groups, organizations, and entities at the Institute. They invited all interested students to join and reach out to any of the entities that could be a good fit for their interests. Chaudhuri reflected afterwards, “Sustainability is inherently interdisciplinary. Every MIT student can incorporate sustainability into their work, regardless of major, class year, or interests! I was excited to join my SSC co-lead, Melissa, in speaking with a diverse group of MISTI interns about how to explore sustainability-related academic, extracurricular, professional, and experiential opportunities at MIT and beyond. These students come from many different disciplines, so it was incredibly heartening to hear that they are all pursuing a climate-related project abroad this summer.”

    Eduardo Rivera, MISTI’s coordinator for climate and sustainability expressed that “educational experiences abroad are a fundamental part of MIT’s mission to foster global leaders to tackle the climate crisis. This summer, more than 110 students will be working around the world in solar and wind technologies, carbon capture, climate adaptation and urban planning, sustainable concrete, electric mobility, among others. We are using this opportunity to expand on the reflection part of the experiential learning cycle. The goal of these pre-departure sessions is to raise awareness and help our students reflect on the impact of their everyday activities on the climate, and to also give them resources to learn and act thoughtfully. We hope they will not only become conscious travelers, but also agents for change.”

    “This year’s climate and sustainability pre-departure training were pilot sessions, and the goal is to expand this learning experience to all MISTI students, not just those working in the fields of climate and sustainability. This will be a unique opportunity to raise awareness and expand the knowledge to over 1,000 of our students as they travel to more than 40 countries across the globe,” explains Abby MacKenzie, MIT-India coordinator who co-developed the pre-departure sessions. More

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    MIT speaker series taps into students’ passion for entrepreneurship and social impact.

    Last summer, leaders of MIT’s Venture Mentoring Service (VMS) noticed a growing trend in entrepreneur applications to the program: An increasing number of aspiring founders were expressing a passion for social impact.

    VMS, which connects students and alumni with teams of mentors, hosts bootcamps, holds expert office hours, and offers an annual Demo Day, did not previously have offerings to help founders focused on this type of impact, so its leaders decided to pilot an Impact Speaker Series.

    The series, which featured experienced early-stage entrepreneurs from the MIT community and took place throughout the year, was a smashing success. In total, more than 1,200 MIT community members registered across eight events, including students at all stages of their education as well as alumni interested in making a positive impact on the world through entrepreneurship.

    “We felt an intense desire from attendees to explore entrepreneurship as a path to solve our most pressing problems,” VMS mentor and series co-Lead Paul Bosco says. “The degree to which students identified with challenges such as climate, health, sustainability, and education, rather than their major, was striking. Our goal was to help them see a path as first-time founders.”

    Now VMS is riding the momentum from the speaker series by rolling out more support services for impact-driven students, including hosting additional events, adding experienced impact entrepreneurs and social enterprise experts to its network of mentors, and connecting with more funders and executives with experience leading organizations focused on impact.

    Ultimately, VMS believes these new efforts will bolster MIT’s broader mission of translating science and innovation from its labs and classrooms into positive advances around the world.

    “Our pivot to strengthen support for founders with a passion for impact is absolutely aligned with the mission of MIT,” Bosco says. “Pursuing research and ideas with a passion for world-changing impact has always been in the DNA of MIT. A new generation of entrepreneurs is challenging us to help them hone their skills and lead organizations to build a better world.”

    Striking a chord

    Each one of VMS’ events had a different theme, from addressing general founder challenges, like first time pre-seed or nondilutive fundraising to building startup ventures in sectors like climate, health care, and education. One panel focused on helping entrepreneurs find their personal paths to success and impact, featuring founders leading impactful companies at different stages of development. Another panel discussion, titled Funding Your Path to Impact and Success, featured investors and directors of programs funding ventures delivering impact.

    “I want to encourage founders to consider driving toward a new ‘unicorn success’ model, where success is not measured in $1-billion-dollar valuations, but is based on world-changing carbon reductions, water cleanliness, lives saved, students inspired, etc.,” Ela Mirowski, a program director with the National Science Foundation, told the audience at one event.

    In total, the events featured 24 expert speakers, early-stage founders, and funders. Impact driven businesses, speakers emphasized, can take many forms. Bosco, who moderated one of the panels, says he’s heard from students and alumni interested in starting for-profit companies focused on profit and impact, what he called “dual bottom lines,” as well as students interested in starting public benefit companies, social enterprises, and traditional nonprofit organizations.

    “VMS is getting better at tapping into the different types of entrepreneurs at different stages of their journeys,” says Akshit Singla SM ’22. “It’s exactly what’s needed, and I know that because there was a huge waitlist for these events.”

    Zahra Kanji, who attended VMS’s most recent event in May and is currently director of MIT Hacking Medicine, sees the speaker series as a natural response to evolving student needs.

    “For students, I think the focus has changed a lot over the years,” Kanji said. “There used to be a lot more interest in entrepreneurship with making money as the final goal, and now it’s turned into more of a triple goal, like a public benefit corporation or something that has more impact. So, hearing key lessons learned from experts is really important — these aren’t answers you can get in a textbook.”

    Listening to the community

    Many of next year’s VMS events will be similar to the events that most resonated with the MIT community this year. VMS will also be adding an event on entrepreneurship in artificial intelligence and computing for impact. VMS is hoping to continue expanding student connections to recent founders, or what Bosco refers to as “near-peer founders,” that can relate more closely with first-time founders navigating the current startup environment.

    “Given that many new entrepreneurs are shifting to focus on impact, we need to evolve,” says VMS mentor Matt Cherian SM ’11. “I’m glad students are starting to think differently, and I’m really glad VMS is making this programming to help people think in this new way.”

    “The most notable aspect of our series was the commitment of students, including undergrads, graduates, and postdocs, pursuing their passion for impact through entrepreneurship,” Bosco says. “Many students we met exploring entrepreneurship for impact have exceptional job offers from top employers, or if they are alums they’re leaving significant positions to pursue a greater purpose in their lives. It is profoundly inspiring and an honor to help each of these founders.” More