More stories

  • in

    Professor Emeritus Richard Wurtman, influential figure in translational research, dies at 86

    Richard Wurtman, the Cecil H. Green Distinguished Professor Emeritus and a member of the MIT faculty for 44 years, died on Dec. 13. He was 86.

    Wurtman received an MD from Harvard Medical School in 1960 and trained at Massachusetts General Hospital before joining the laboratory of Nobel laureate Julius Axelrod at the National Institutes of Health in 1962. In 1967, MIT invited him to start a neurochemistry and neuropharmacology program in the Department of Nutrition and Food Science. In the early 1980s he joined the newly formed Department of Brain and Cognitive Sciences. Wurtman was also deeply involved in the National Institutes of Health-established Clinical Research Center at MIT, which he also directed for 25 years.

    His initial placement in Nutrition and Food Science was fortuitous, recalled Wurtman in a 2011 profile, because it “sensitized me to the fact that nutrients are chemicals the way drugs are chemicals. A compound like folic acid is a vitamin in foods, but when given alone in higher doses it becomes a drug that safeguards the developing nervous system.”

    Wurtman’s search for new biological properties and therapeutic uses of known molecules — hormones, nutrients, or existing pharmaceuticals — was highly fruitful. His research on the pineal gland, which started when he was a medical student, led to the discovery that melatonin, the hormone made by the gland, regulates sleep. 

    “Dick Wurtman was a pioneer in studying the role of neurotransmitters in the brain, and neuroendocrine regulation of normal and abnormal brain function,” says Newton Professor of Neuroscience Mriganka Sur, who served as head of the Department of Brain and Cognitive Sciences from 1997 to 2012. “His work on the impact of nutrition on neurotransmitters such as acetylcholine and on neuronal membrane synthesis laid the groundwork for later translational work on brain diseases such as Alzheimer’s disease.”

    Wurtman’s lab discovered that consuming carbohydrates increases tryptophan levels in the brain and consequently the production of the neurotransmitter serotonin. This led to a long collaboration with his wife Judith Wurtman, an MIT research affiliate, in which they found that carbohydrates were often consumed by individuals as a form of self-medication when they experienced changes in mood, such as late in the afternoon or when suffering from premenstrual syndrome (PMS). The Wurtmans’ research led to the development of Sarafem, the first drug for severe PMS, and a drink, PMS Escape, used for milder forms of this syndrome.

    To commercialize some of his findings, Wurtman founded Interneuron Pharmaceuticals in 1988; the company was renamed Indevus in 2002 and acquired by Endo Pharmaceuticals in 2009.

    Wurtman’s research advanced the idea that substrate availability, and not simply enzyme activity, can control metabolic processes in the brain. He discovered that the dietary availability of neurotransmitter precursors (e.g., acetylcholine, dopamine, and GABA) can increase their levels in the brain and modulate their metabolism. Moreover, he applied this concept to synaptic structural components such as brain phosphatides and found that dietary intake of three rate-limiting precursors — uridine, choline, and the omega-3 fatty acid DHA — led to increased brain phosphatide levels, increased dendritic spine density, and improved memory performance. These findings led to the development of Souvenaid, a specifically formulated multi-nutrient drink based on the three essential phosphatide precursors of Wurtman’s later research. It has been the subject of numerous clinical trials for Alzheimer’s disease, and, most recently, for age-related cognitive decline.

    “Dick Wurtman was a pioneer on studying how nutrients influence brain function,” says Li-Huei Tsai, Picower Professor of Neuroscience and director of The Picower Institute for Learning and Memory. “His nutrient clinical trial work and establishment of the MIT Clinical Research Center have been tremendously helpful for my own work on understanding how high doses of supplement choline could potentially help reduce certain Alzheimer’s risk, and our team’s development of clinical studies at MIT to test Alzheimer’s therapies.”

    “Dick’s legacy resides within the careers of hundreds of trainees and collaborators he launched or enhanced, the 1,000-plus published research articles, his numerous patent awards, and people who benefited from his therapeutic approaches,” says former postdoc Bertha Madras, now a professor of psychobiology at McLean Hospital and Harvard Medical School. “Yet, these quantitative metrics, legacies of research and mentoring, do not illustrate the charitable qualities of this remarkable man. I witnessed his deep intellect, boundless energy, enthusiasm, optimism, and generosity toward trainees, qualities that helped to sustain me during crests and troughs encountered in the adventures of a scientific career. Dr. Richard Wurtman was a creative, brilliant scientist, a mentor, a devoted husband to his beloved wife.”

    “Dick was an inspiration, a motivation, and a guide to all his students and colleagues in shaping thoughts to be precise and purposeful,” says Tony Nader PhD ’89, who did his doctoral research with Wurtman. “His rigorous scientific approach and the application of his findings have contributed to make life better. His legacy is huge.”

    Richard and Judith Wurtman have also made a lasting philanthropic impact at MIT. They endowed a professorship in the Department of Brain and Cognitive Sciences in honor of the late Institute Professor and provost Walter Rosenblith; the chair was held first by Ann Graybiel, who is now an Institute Professor; Nancy Kanwisher is the current Walter A. Rosenblith Professor of Cognitive Neuroscience. The Wurtmans have also been longtime supporters of MIT Hillel.

    Elazer R. Edelman, the Edward J. Poitras Professor in Medical Engineering and Science at MIT, professor of medicine at Harvard Medical School, and director of the MIT Institute for Medical Engineering and Science, recalls that Wurtman was also supportive of the Harvard-MIT Program in Health Sciences and Technology: “He changed our school and our world — he and Judith coupled immense charity with exceptional intellect and they made us all better for it.”

    Richard Wurtman is survived by his wife, Judith; daughter Rachael; son David and daughter-in-law Jean Chang; and grandchildren Dvora Toren, Yael Toren and Jacob Vider.  More

  • in

    MIT community in 2022: A year in review

    In 2022, MIT returned to a bit of normalcy after the challenge of Covid-19 began to subside. The Institute prepared to bid farewell to its president and later announced his successor; announced five flagship projects in a new competition aimed at tackling climate’s greatest challenges; made new commitments toward ensuring support for diverse voices; and celebrated the reopening of a reimagined MIT Museum — as well as a Hollywood blockbuster featuring scenes from campus. Here are some of the top stories in the MIT community this year.

    Presidential transition

    In February, MIT President L. Rafael Reif announced that he planned to step down at the end of 2022. In more than 10 years as president, Reif guided MIT through a period of dynamic growth, greatly enhancing its global stature and magnetism. At the conclusion of his term at the end of this month, Reif will take a sabbatical, then return to the faculty of the Department of Electrical Engineering and Computer Science. In September, Reif expressed his gratitude to the MIT community at an Institute-wide dance celebration, and he was honored with a special MIT Dome lighting earlier this month.

    After an extensive presidential search, Sally Kornbluth, a cell biologist and the current provost of Duke University, was announced in October as MIT’s 18th president. Following an introduction to MIT that included a press conference, welcoming event, and community celebration, Kornbluth will assume the MIT presidency on Jan. 1, 2023.

    In other administrative transitions: Cynthia Barnhart was appointed provost after Martin Schmidt stepped down to become president of Rensselaer Polytechnic Institute; Sanjay Sarma stepped down as vice president for open learning after nine years in the role; professors Brent Ryan and Anne White were named associate provosts, while White was also named associate vice president for research administration; and Agustín Rayo was named dean of the School of Humanities, Arts, and Social Sciences.

    Climate Grand Challenges

    MIT announced five flagship projects in its first-ever Climate Grand Challenges competition. These multiyear projects focus on unraveling some of the toughest unsolved climate problems and bringing high-impact, science-based solutions to the world on an accelerated basis. Representing the most promising concepts to emerge from the two-year competition that yielded 27 finalist projects, the five flagship projects will receive additional funding and resources from MIT and others to develop their ideas and swiftly transform them into practical solutions at scale.

    CHIPS and Science Act

    President Reif and Vice President for Research Maria Zuber were among several MIT representatives to witness President Biden’s signing of the $52 billion “CHIPS and Science” bill into law in August. Reif helped shape aspects of the bill and was a vocal advocate for it among university and government officials, while Zuber served on two government science advisory boards during the bill’s gestation and consideration. Earlier in the year, MIT.nano hosted U.S. Secretary of Commerce Gina Raimondo, while MIT researchers released a key report on U.S. microelectronics research and manufacturing.

    MIT Morningside Academy for Design

    Supported by a $100 million founding gift, the MIT Morningside Academy for Design launched as a major interdisciplinary center that aims to build on the Institute’s leadership in design-focused education. Housed in the School of Architecture and Planning, the academy provides a hub that will encourage design work at MIT to grow and cross disciplines among engineering, science, management, computing, architecture, urban planning, and the arts.

    Reports of the Institute

    A number of key Institute reports and announcements were released in 2022. They include: an announcement of the future of gift acceptance for MIT: an announcement of priority MIT investments; a new MIT Values Statement; a renewed commitment to Indigenous scholarship and community; the Strategic Action Plan for Belonging, Achievement, and Composition; a report on MIT’s engagement with China; a report of the Working Group on Reimagining Public Safety at MIT; a report of the Indigenous Working Group; and a report of the Ad Hoc Committee on Arts, Culture, and DEI.

    Nobel Prizes

    MIT affiliates were well-represented among new and recent Nobel laureates who took part in the first in-person Nobel Prize ceremony since the start of the Covid-19 pandemic. MIT-affiliated winners for 2022 included Ben Bernanke PhD ’79, K. Barry Sharpless, and Carolyn Bertozzi. Winners in attendance from 2020 and 2021 included Professor Joshua Angrist, David Julius ’77, and Andrea Ghez ’87.

    New MIT Museum

    A reimagined MIT Museum opened this fall in a new 56,000-square-foot space in the heart of Cambridge’s Kendall Square. The museum invites visitors to explore the Institute’s innovations in science, technology, engineering, arts, and math — and to take part in that work with hands-on learning labs and maker spaces, interactive exhibits, and venues to discuss the impact of science and technology on society.

    “Wakanda Forever”

    In November, the Institute Office of Communications and the Division of Student Life hosted a special screening of Marvel Studios’ “Black Panther: Wakanda Forever.” The MIT campus had been used as a filming location in summer 2021, as one of the film’s characters, Riri Williams (also known as Ironheart), is portrayed as a student at the Institute.

    In-person Commencement returns

    After two years of online celebrations due to Covid-19, MIT Commencement returned to Killian Court at the end of May. World Trade Organization Director-General Ngozi Okonjo-Iweala MCP ’78, PhD ’81 delivered the Commencement address, while poet Kealoha Wong ’99 spoke at a special ceremony for the classes of 2020 and 2021.

    Students win distinguished fellowships

    As in previous years, MIT students continued to shine. This year, exceptional undergraduates were awarded Fulbright, Marshall, Mitchell, Rhodes, and Schwarzman scholarships.

    Remembering those we’ve lost

    Among MIT community members who died this year were Robert Balluffi, Louis Braida, Ashton Carter, Tom Eagar, Dick Eckaus, Octavian-Eugen Ganea, Peter Griffith, Patrick Hale, Frank Sidney Jones, Nonabah Lane, Leo Marx, Bruce Montgomery, Joel Moses, Brian Sousa Jr., Mohamed Magdi Taha, John Tirman, Richard Wurtman, and Markus Zahn.

    In case you missed it:

    Additional top community stories of 2022 included MIT students dominating the 82nd Putnam Mathematical Competition, an update on MIT’s reinstating the SAT/ACT requirement for admissions, a new mathematics program for Ukrainian students and refugees, a roundup of new books from MIT authors, the renaming of the MIT.nano building, an announcement of winners of this year’s MIT $100K Entrepreneurship Competition, the new MIT Wright Brothers Wind Tunnel, and MIT students winning the 45th International Collegiate Programming Contest for the first time in 44 years. More

  • in

    Food for thought, thought for food

    According to the Food and Agriculture Organization of the United Nations, approximately 3.1 billion people worldwide were unable to afford a healthy diet in 2020. Meanwhile, in 2021 close to 2.3 billion people were moderately or severely food insecure. Given the strong link between malnutrition and income disparity, the numbers paint a grim picture representing one of the grand challenges of our time.

    “I’m probably an idealist,” says MIT Research Scientist Christopher Mejía Argueta, “but I really believe that if we change our diets and think about ways to help others, we can make a difference — that’s my motivation.”

    Mejía Argueta is the founder and director of the MIT Food and Retail Operations Lab (FaROL). He has more than a decade of experience in supply chain management, optimization, and effective data-driven decision-making on pressing issues like the evolution of end consumers for retail and e-tail supply chains, food waste, and equitable access to nutrition.  

    Supply chain network designs typically focus on minimizing costs without considering the implications (e.g., cost) of changes in consumer behavior. Mejía Argueta and his colleagues at the FaROL, however, are working to understand and design optimal supply chains to create high-performance operations based on consumer choice. “Understanding the significant factors of consumer choice and analyzing their evolution over time becomes critical to designing forward-looking retail operations with data-driven and customer-centric supply chains, inventory management, and distribution systems,” explains Mejía Argueta. 

    Play video

    One of his recent projects examined the challenges of small retailers worldwide. These mom-and-pop outlets, or nanostores, account for 50 percent of the global market share and are the primary source of consumer packaged goods for people in urban areas. Worldwide there are nearly 50 million nanostores, each serving between 100-200 households in a community. In India alone, there are 14 million nanostores known as kiranas. And while these retailers are more prevalent in emerging markets, they play an important role in developed markets, particularly in under-resourced communities, and are frequently located in “food deserts,” where they are the only source of essential goods for the community.  

    These small retailers thrive thanks, partly, to their ability to offer the right combination of affordability and convenience while fostering trust with local customers, who often lack access to a supermarket or a grocery store. They often exist in fragmented, densely populated areas where infrastructure and public transportation services are poor and consumers have limited purchasing power. But nanostore shopkeepers and owners are intimately familiar with their customers and their consumption patterns, which means they can connect those consumption patterns or information to the larger supply chain. According to Mejía Argueta, when it comes to the future of retail, nanostores will be the cornerstones of growth in emerging economies. 

    But it’s a complicated scenario. Mom-and-pop shops don’t have the capacity to offer a broad range of products to their customers, and often, they lack access to nutritious food options. Logistically speaking, it is expensive to supply them, and the cost-to-serve (i.e., the logistics cost) is between 10 to 30 percent more expensive than other retailers. According to Mejía Argueta, this has a significant ripple effect, impacting education, productivity, and, eventually, the economic performance of an entire nation.  

    “The high fragmentation of nanostores causes substantial distribution inefficiencies, especially in congested megacities,” he says. “At my lab, we study how to make nanostores more efficient and effective by considering various commercial and logistics strategies while considering inherent technical challenges. We need to serve these small retailers better to help them survive and thrive, to provide a greater impact for underserved communities and the entire economic ecosystem.”

    Play video

    Mejía Argueta and his team recently collaborated with Tufts University and the City of Somerville, Massachusetts, to conduct research on food access models in underserved communities. The Somerville Project explored various interventions to supply fresh produce in food desert neighborhoods.

    “A lack of nutrition does not simply mean a lack of food,” Mejía Argueta says. “It can also be caused by an overabundance of unhealthy foods in a given market, which is particularly troublesome for U.S. cities where people in underserved communities don’t have access to healthy food options. We believe that one way to combat the problem of food deserts is to supply these areas with healthy food options affordably and create awareness programs.”  

    The collaborative project saw Mejía Argueta and his colleagues assessing the impact of several intervention schemes designed to empower the end consumer. For example, they implemented a low-cost grocery delivery model similar to Instacart as well as a ride sharing system to transport people from their homes to grocery stores and back. They also collaborated with a nonprofit organization, Partnership for a Healthier America, and began working with retailers to deliver “veggie boxes” in underserved communities. Models like these provide low-income people access to food while providing dignity of choice, Mejía Argueta explains.  

    When it comes to supply chain management research, sustainability and societal impact often fall by the wayside, but Mejía Argueta’s bottom-up approach shirks tradition. “We’re trying to build a community, employing a socially driven perspective because if you work with the community, you gain their trust. If you want to make something sustainable in the long term, people need to trust in these solutions and engage with the ecosystem as a whole.”  

    And to achieve real-world impact, collaboration is key. Mejía Argueta says that government has an important role to play, developing policy to connect the models he and his colleagues develop in academia to societal challenges. Meanwhile, he believes startups and entrepreneurs can function as bridge-builders to link the flows of information, the flows of goods and cash, and even knowledge and security in an ecosystem that suffers from fragmentation and siloed thinking among stakeholders.

    Finally, Mejía Argueta reflects on the role of corporations and his belief that the MIT Industrial Liaison Program is essential to getting his research to the frontline of business challenges. “The Industrial Liaison Program does a fantastic job of connecting our research to real-world scenarios,” he says. “It creates opportunities for us to have meaningful interactions with corporates for real-world impact. I believe strongly in the MIT motto ‘mens et manus,’ and ILP helps drive our research into practice.” More

  • in

    Microparticles could help prevent vitamin A deficiency

    Vitamin A deficiency is the world’s leading cause of childhood blindness, and in severe cases, it can be fatal. About one-third of the global population of preschool-aged children suffer from this vitamin deficiency, which is most prevalent in sub-Saharan Africa and South Asia.

    MIT researchers have now developed a new way to fortify foods with vitamin A, which they hope could help to improve the health of millions of people around the world. In a new study, they showed that encapsulating vitamin A in a protective polymer prevents the nutrient from being broken down during cooking or storage.

    “Vitamin A is a very important micronutrient, but it’s an unstable molecule,” says Ana Jaklenec, a research scientist at MIT’s Koch Institute for Integrative Cancer Research. “We wanted to see if our encapsulated vitamin A could fortify a food vehicle like bouillon cubes or flour, throughout storage and cooking, and whether the vitamin A could remain biologically active and be absorbed.”

    In a small clinical trial, the researchers showed that when people ate bread fortified with encapsulated vitamin A, the bioavailability of the nutrient was similar to when they consumed vitamin A on its own. The technology has been licensed to two companies that hope to develop it for use in food products.

    “This is a study that our team is really excited about because it shows that everything we did in test tubes and animals works safely and effectively in humans,” says Robert Langer, the David H. Koch Institute Professor at MIT and a member of the Koch Institute. “We hope this opens the door for someday helping millions, if not billions, of people in the developing world.”

    Jaklenec and Langer are the senior authors of the new study, which appears this week in the Proceedings of the National Academy of Sciences. The paper’s lead author is former MIT postdoc Wen Tang, who is now an associate professor at South China University of Technology.

    Nutrient stability

    Vitamin A is critical not only for vision but also the functioning of the immune system and organs such as the heart and lungs. Efforts to add vitamin A to bread or other foods such as bouillon cubes, which are commonly consumed in West African countries, have been largely unsuccessful because the vitamin breaks down during storage or cooking.

    In a 2019 study, the MIT team showed that they could use a polymer called BMC to encapsulate nutrients, including iron, vitamin A, and several others. They showed that this protective coating improved the shelf life of the nutrients, and that people who consumed bread fortified with encapsulated iron were able to absorb the iron.

    BMC is classified by the FDA as “generally regarded as safe,” and is already used in coatings for drugs and dietary supplements. In the new study, the researchers focused on using this polymer to encapsulate vitamin A, a nutrient that is very sensitive to temperature and ultraviolet light.

    Using an industrial process known as a spinning disc process, the researchers mixed vitamin A with the polymer to form particles 100 to 200 microns in diameter. They also coated the particles with starch, which prevents them from sticking to each other.

    The researchers found that vitamin A encapsulated in the polymer particles were more resistant to degradation by intense light, high temperatures, or boiling water. Under those conditions, much more vitamin A remained active than when the vitamin A was free or when it was delivered in a form called VitA 250, which is currently the most stable form of vitamin A used for food fortification.

    The researchers also showed that the encapsulated particles could be easily incorporated into flour or bouillon cubes. To test how well they would survive long-term storage, the researchers exposed the cubes to harsh conditions, as recommended by the World Health Organization: 40 degrees Celsius (104 degrees Fahrenheit) and 75 percent humidity. Under those conditions, the encapsulated vitamin A was much more stable than other forms of vitamin A. 

    “The enhanced stability of vitamin A with our technology can ensure that the vitamin A-fortified food does provide the recommended daily uptake of vitamin A, even after long-term storage in a hot humidified environment, and cooking processes such as boiling or baking,” Tang says. “People who are suffering from vitamin A deficiency and want to get vitamin A through fortified food will benefit, without changing their daily routines, and without wondering how much vitamin A is still in the food.”

    Vitamin absorption

    When the researchers cooked their encapsulated particles and then fed them to animals, they found that 30 percent of the vitamin A was absorbed, the same as free uncooked vitamin A, compared to about 3 percent of free vitamin A that had been cooked.

    Working with Biofortis, a company that does dietary clinical testing, the researchers then evaluated how well vitamin A was absorbed in people who ate foods fortified with the particles. For this study, the researchers incorporated the particles into bread, then measured vitamin A levels in the blood over a 24-hour period after the bread was consumed. They found that when vitamin A was encapsulated in the BMC polymer, it was absorbed from the food at levels comparable to free vitamin A, indicating that it is readily released in bioactive form.

    Two companies have licensed the technology and are focusing on developing products fortified with vitamin A and other nutrients. A benefit corporation called Particles for Humanity, funded by the Bill and Melinda Gates Foundation, is working with partners in Africa to incorporate this technology into existing fortification efforts. Another company called VitaKey, founded by Jaklenec, Langer, and others, is working on using this approach to add nutrients to a variety of foods and beverages.

    The research was funded by the Bill and Melinda Gates Foundation. Other authors of the paper include Jia Zhuang, Aaron Anselmo, Xian Xu, Aranda Duan, Ruojie Zhang, James Sugarman, Yingying Zeng, Evan Rosenberg, Tyler Graf, Kevin McHugh, Stephany Tzeng, Adam Behrens, Lisa Freed, Lihong Jing, Surangi Jayawardena, Shelley Weinstock, Xiao Le, Christopher Sears, James Oxley, John Daristotle, and Joe Collins. More

  • in

    New nanosatellite tests autonomy in space

    In May 2022, a SpaceX Falcon 9 rocket launched the Transporter-5 mission into orbit. The mission contained a collection of micro and nanosatellites from both industry and government, including one from MIT Lincoln Laboratory called the Agile MicroSat (AMS).

    AMS’s primary mission is to test automated maneuvering capabilities in the tumultuous very low-Earth orbit (VLEO) environment, starting at 525 kilometers above the surface and lowering down. VLEO is a challenging location for satellites because the higher air density, coupled with variable space weather, causes increased and unpredictable drag that requires frequent maneuvers to maintain position. Using a commercial off-the-shelf electric-ion propulsion system and custom algorithms, AMS is testing how well it can execute automated navigation and control over an initial mission period of six months.

    “AMS integrates electric propulsion and autonomous navigation and guidance control algorithms that push a lot of the operation of the thruster onto the spacecraft — somewhat like a self-driving car,” says Andrew Stimac, who is the principal investigator for the AMS program and the leader of the laboratory’s Integrated Systems and Concepts Group.

    Stimac sees AMS as a kind of pathfinder mission for the field of small satellite autonomy. Autonomy is essential to support the growing number of small satellite launches for industry and science because it can reduce the cost and labor needed to maintain them, enable missions that call for quick and impromptu responses, and help to avoid collisions in an already-crowded sky.

    AMS is the first-ever test of a nanosatellite with this type of automated maneuvering capability.

    AMS uses an electric propulsion thruster that was selected to meet the size and power constraints of a nanosatellite while providing enough thrust and endurance to enable multiyear missions that operate in VLEO. The flight software, called the Bus Hosted Onboard Software Suite, was designed to autonomously operate the thruster to change the spacecraft’s orbit. Operators on the ground can give AMS a high-level command, such as to descend to and maintain a 300-kilometer orbit, and the software will schedule thruster burns to achieve that command autonomously, using measurements from the onboard GPS receiver as feedback. This experimental software is separate from the bus flight software, which allows AMS to safely test its novel algorithms without endangering the spacecraft.

    “One of the enablers for AMS is the way in which we’ve created this software sandbox onboard the spacecraft,” says Robert Legge, who is another member of the AMS team. “We have our own hosted software that’s running on the primary flight computer, but it’s separate from the critical health and safety avionics software. Basically, you can view this as being a little development environment on the spacecraft where we can test out different algorithms.”

    AMS has two secondary missions called Camera and Beacon. Camera’s mission is to take photos and short video clips of the Earth’s surface while AMS is in different low-Earth orbit positions.

    “One of the things we’re hoping to demonstrate is the ability to respond to current events,” says Rebecca Keenan, who helped to prepare the Camera payload. “We could hear about something that happened, like a fire or flood, and then respond pretty quickly to maneuver the satellite to image it.”

    Keenan and the rest of the AMS team are collaborating with the laboratory’s DisasterSat program, which aims to improve satellite image processing pipelines to help relief agencies respond to disasters more quickly. Small satellites that could schedule operations on-demand, rather than planning them months in advance before launch, could be a great asset to disaster response efforts.

    The other payload, Beacon, is testing new adaptive optics capabilities for tracking fast-moving targets by sending laser light from the moving satellite to a ground station at the laboratory’s Haystack Observatory in Westford, Massachusetts. Enabling precise laser pointing from an agile satellite could aid many different types of space missions, such as communications and tracking space debris. It could also be used for emerging programs such as Breakthrough Starshot, which is developing a satellite that can accelerate to high speeds using a laser-propelled lightsail.

    “As far as we know, this is the first on-orbit artificial guide star that has launched for a dedicated adaptive optics purpose,” says Lulu Liu, who worked on the Beacon payload. “Theoretically, the laser it carries can be maneuvered into position on other spacecraft to support a large number of science missions in different regions of the sky.”

    The team developed Beacon with a strict budget and timeline and hope that its success will shorten the design and test loop of next-generation laser transmitter systems. “The idea is that we could have a number of these flying in the sky at once, and a ground system can point to one of them and get near-real-time feedback on its performance,” says Liu.

    AMS weighs under 12 kilograms with 6U dimensions (23 x 11 x 36 centimeters). The bus was designed by Blue Canyon Technologies and the thruster was designed by Enpulsion GmbH.

    Legge says that the AMS program was approached as an opportunity for Lincoln Laboratory to showcase its ability to conduct work in the space domain quickly and flexibly. Some major roadblocks to rapid development of new space technology have been long timelines, high costs, and the extremely low risk tolerance associated with traditional space programs. “We wanted to show that we can really do rapid prototyping and testing of space hardware and software on orbit at an affordable cost,” Legge says.

    “AMS shows the value and fast time-to-orbit afforded by teaming with rapid space commercial partners for spacecraft core bus technologies and launch and ground segment operations, while allowing the laboratory to focus on innovative mission concepts, advanced components and payloads, and algorithms and processing software,” says Dan Cousins, who is the program manager for AMS. “The AMS team appreciates the support from the laboratory’s Technology Office for allowing us to showcase an effective operating model for rapid space programs.”

    AMS took its first image on June 1, completed its thruster commissioning in July, and has begun to descend toward its target VLEO position. More

  • in

    Using game engines and “twins” to co-create stories of climate futures

    Imagine entering a 3D virtual story world that’s a digital twin of an existing physical space but also doubles as a vessel to dream up speculative climate stories and collective designs. Then, those imagined worlds are translated back into concrete plans for our physical spaces.

    Five multidisciplinary teams recently convened at MIT — virtually — for the inaugural WORLDING workshop. In a weeklong series of research and development gatherings, the teams met with MIT scientists, staff, fellows, students and graduates as well as other leading figures in the field. The theme of the gathering was “story, space, climate, and game engines.”

    “WORLDING illustrates the emergence of an entirely new field that fuses urban planning, climate science, real-time 3D engines, nonfiction storytelling, and speculative fiction,” says Katerina Cizek, lead designer of the workshop at Co-Creation Studio, MIT Open Documentary Lab. “And co-creation is at the core of this field that allows for collective, democratic, scientific and artistic processes.” The research workshop was organized by the studio in partnership with Unity Software.

    The WORLDING teams met with MIT scholars to discuss diverse domains, from the decolonization of board games, to urban planning as acts of democracy, to behind the scenes of a flagship MIT Climate Challenge project.

    “Climate is really a whole-world initiative,” said Noelle Selin, an MIT atmospheric chemistry professor, in a talk at WORLDING. Selin co-leads an MIT initiative that is digitally twinning the Earth to harness enormous volumes of data for improved climate projections and put these models into the hands of diverse communities and stakeholders.

    “Digital twinning” is a growth market for the game engine industry, in verticals such as manufacturing, architecture, finance, and medicine. “Digital twinning gives teams the power to ideate,” said Elizabeth Baron, a senior manager of enterprise solutions at Unity in her talk at WORLDING. “You can look at many things that maybe aren’t even possible to produce. But you’re the resource. Impact is very low, but the creativity aspect is very high.”

    That’s where the story and media experts come in. “Now, more than ever, we need to forge shared narratives about the world that we live in today and the world that we want to build for the future. Technology can help us visualize and communicate those worlds,” says Marina Psaros MCP ’06, head of sustainability at Unity, lead on WORLDING at Unity, and a graduate of the MIT Department of Urban Studies and Planning.

    In his talk on the short history of WORLDING, media scholar William Uricchio, MIT professor of comparative media studies and founder of the Open Documentary Lab, suggested that story and space come together in these projects that create new ways of knowing. “Story is always a representation,” he says. “It’s got a fixity and coherence to it, and play is — and, I would argue, worlds are —  all about simulation. Simulation in the case of digital twinning is capable of generating countless stories. It’s play as a story-generator, but in the service of envisioning a pluralistic and malleable future.”

    Fixed dominant narratives and game mechanics that underpin board games have been historically violent and unjust, says MIT Game Lab scholar Mikael Jakkobson, who shared findings for his upcoming book on the subject with the cohort. He argues that board games are built on underlying ideas of  “exploration, expansion, exploitation, and extermination. And, as it happens, those are also good ways of thinking about the mechanics of Western colonialism.”

    To counter these hegemonic mechanics and come up with new systems, community is vital, and urban planning is a discipline that plays a huge role in the translation of space, story, and democracy. Ceasar MacDowell, an MIT professor of the practice of civic design, told the WORLDING cohort that urban planning needs to expand its notion of authorship. He is working on systems (from his current position at the Media Lab) that not only engage the community in conversations but also prompt “the people who have been in conversations to actually make sense of them, do the meaning-making themselves, not to have external people interpret them.” These become dynamic layers of both representation and simulation that are not, as Uricchio suggests, fixed. 

    USAID Chief Climate Officer Gillian Calwell visited the group with both sharp warnings and warm enthusiasm: “When it comes to climate, this world isn’t working so well for us; we better start envisioning the new ones, and fast … We don’t have time to convince people that this is happening anymore. Nor do we need to. I think most of the world is having the hands-on, up-close-and-personal experience with the fact that these impacts are coming faster and more furiously than even the scientists had predicted. But one thing we do need help with on a more hopeful note is visualizing how the world could be different.”

    The WORLDING workshop is designed and inspired by the ideas and practices charted in the Co-Creation Studio’s new MIT Press book, “Collective Wisdom: Co-Creation Media for Equity and Justice,” which insists that “No one person, organization, or discipline can determine all the answers alone.”

    The five multidisciplinary teams in this first WORLDING cohort were diverse in approach, technology, and geography. For example, one is an Indigenous-led, land-based, site-specific digital installation that seeks to envision a future in which, once again, the great herds of buffalo walk freely. Another team is creating 3D-modeled biome kits of the water systems in the drought-stricken American West, animated by interviews and data from the communities living there. Yet another team is digitally twinning and then re-imagining a sustainable future in the year 2180 for a multi-player virtual reality game in a Yawanawà Shukuvena Village in the rainforests of Brazil.

    “While our workshop design was focused on developing and researching these incredible, interdisciplinary projects, we also hope that WORLDING can set an example for similar initiatives across global sectors where distances and varied expertise are not limitations but opportunities to learn from one another,” says Srushti Kamat, WORLDING producer and MIT creative media studies/writing grad.

    Most of the talks and presentations from the WORLDING workshop are available as archived videos at cocreationstudio.mit.edu/worlding-videos. More

  • in

    MIT Policy Hackathon produces new solutions for technology policy challenges

    Almost three years ago, the Covid-19 pandemic changed the world. Many are still looking to uncover a “new normal.”

    “Instead of going back to normal, [there’s a new generation that] wants to build back something different, something better,” says Jorge Sandoval, a second-year graduate student in MIT’s Technology and Policy Program (TPP) at the Institute for Data, Systems and Society (IDSS). “How do we communicate this mindset to others, that the world cannot be the same as before?”

    This was the inspiration behind “A New (Re)generation,” this year’s theme for the IDSS-student-run MIT Policy Hackathon, which Sandoval helped to organize as the event chair. The Policy Hackathon is a weekend-long, interdisciplinary competition that brings together participants from around the globe to explore potential solutions to some of society’s greatest challenges. 

    Unlike other competitions of its kind, Sandoval says MIT’s event emphasizes a humanistic approach. “The idea of our hackathon is to promote applications of technology that are humanistic or human-centered,” he says. “We take the opportunity to examine aspects of technology in the spaces where they tend to interact with society and people, an opportunity most technical competitions don’t offer because their primary focus is on the technology.”

    The competition started with 50 teams spread across four challenge categories. This year’s categories included Internet and Cybersecurity, Environmental Justice, Logistics, and Housing and City Planning. While some people come into the challenge with friends, Sandoval said most teams form organically during an online networking meeting hosted by MIT.

    “We encourage people to pair up with others outside of their country and to form teams of different diverse backgrounds and ages,” Sandoval says. “We try to give people who are often not invited to the decision-making table the opportunity to be a policymaker, bringing in those with backgrounds in not only law, policy, or politics, but also medicine, and people who have careers in engineering or experience working in nonprofits.”

    Once an in-person event, the Policy Hackathon has gone through its own regeneration process these past three years, according to Sandoval. After going entirely online during the pandemic’s height, last year they successfully hosted the first hybrid version of the event, which served as their model again this year.

    “The hybrid version of the event gives us the opportunity to allow people to connect in a way that is lost if it is only online, while also keeping the wide range of accessibility, allowing people to join from anywhere in the world, regardless of nationality or income, to provide their input,” Sandoval says.

    For Swetha Tadisina, an undergraduate computer science major at Lafayette College and participant in the internet and cybersecurity category, the hackathon was a unique opportunity to meet and work with people much more advanced in their careers. “I was surprised how such a diverse team that had never met before was able to work so efficiently and creatively,” Tadisina says.

    Erika Spangler, a public high school teacher from Massachusetts and member of the environmental justice category’s winning team, says that while each member of “Team Slime Mold” came to the table with a different set of skills, they managed to be in sync from the start — even working across the nine-and-a-half-hour time difference the four-person team faced when working with policy advocate Shruti Nandy from Calcutta, India.

    “We divided the project into data, policy, and research and trusted each other’s expertise,” Spangler says, “Despite having separate areas of focus, we made sure to have regular check-ins to problem-solve and cross-pollinate ideas.”

    During the 48-hour period, her team proposed the creation of an algorithm to identify high-quality brownfields that could be cleaned up and used as sites for building renewable energy. Their corresponding policy sought to mandate additional requirements for renewable energy businesses seeking tax credits from the Inflation Reduction Act.

    “Their policy memo had the most in-depth technical assessment, including deep dives in a few key cities to show the impact of their proposed approach for site selection at a very granular level,” says Amanda Levin, director of policy analysis for the Natural Resources Defense Council (NRDC). Levin acted as both a judge and challenge provider for the environmental justice category.

    “They also presented their policy recommendations in the memo in a well-thought-out way, clearly noting the relevant actor,” she adds. This clarity around what can be done, and who would be responsible for those actions, is highly valuable for those in policy.”

    Levin says the NRDC, one of the largest environmental nonprofits in the United States, provided five “challenge questions,” making it clear that teams did not need to address all of them. She notes that this gave teams significant leeway, bringing a wide variety of recommendations to the table. 

    “As a challenge partner, the work put together by all the teams is already being used to help inform discussions about the implementation of the Inflation Reduction Act,” Levin says. “Being able to tap into the collective intelligence of the hackathon helped uncover new perspectives and policy solutions that can help make an impact in addressing the important policy challenges we face today.”

    While having partners with experience in data science and policy definitely helped, fellow Team Slime Mold member Sara Sheffels, a PhD candidate in MIT’s biomaterials program, says she was surprised how much her experiences outside of science and policy were relevant to the challenge: “My experience organizing MIT’s Graduate Student Union shaped my ideas about more meaningful community involvement in renewables projects on brownfields. It is not meaningful to merely educate people about the importance of renewables or ask them to sign off on a pre-planned project without addressing their other needs.”

    “I wanted to test my limits, gain exposure, and expand my world,” Tadisina adds. “The exposure, friendships, and experiences you gain in such a short period of time are incredible.”

    For Willy R. Vasquez, an electrical and computer engineering PhD student at the University of Texas, the hackathon is not to be missed. “If you’re interested in the intersection of tech, society, and policy, then this is a must-do experience.” More

  • in

    Machinery of the state

    In Mai Hassan’s studies of Kenya, she documented the emergence of a sprawling administrative network officially billed as encouraging economic development, overseeing the population, and bolstering democracy. But Hassan’s field interviews and archival research revealed a more sinister purpose for the hundreds of administrative and security offices dotting the nation: “They were there to do the presidents’ bidding, which often involved coercing their own countrymen.”

    This research served as a catalyst for Hassan, who joined MIT as an associate professor of political science in July, to investigate what she calls the “politicized management of bureaucracy and the state.” She set out to “understand the motivations, capacities, and roles of people administering state programs and social functions,” she says. “I realized the state is not a faceless being, but instead comprised of bureaucrats carrying out functions on behalf of the state and the regime that runs it.”

    Today, Hassan’s portfolio encompasses not just the bureaucratic state but democratization efforts in Kenya and elsewhere in the East Africa region, including her native Sudan. Her research highlights the difficulties of democratization. “I’m finding that the conditions under which people come together for overthrowing an autocratic regime really matter, because those conditions may actually impede a nation from achieving democracy,” she says.

    A coordinated bureaucracy

    Hassan’s academic engagement with the state’s administrative machinery began during graduate school at Harvard University, where she earned her master’s and doctorate in government. While working with a community trash and sanitation program in some Kenyan Maasai communities, Hassan recalls “shepherding myself from office to office, meeting different bureaucrats to obtain the same approvals but for different jurisdictions.” The Kenyan state had recently set up hundreds of new local administrative units, motivated by what it claimed was the need for greater efficiency. But to Hassan’s eyes, “the administrative network was not well organized, seemed costly to maintain, and seemed to hinder — not bolster — development,” she says. What then, she wondered, was “the political logic behind such state restructuring?”

    Hassan began researching this bureaucratic transformation of Kenya, speaking with administrators in communities large and small who were charged with handling the business of the state. These studies yielded a wealth of findings for her dissertation, and for multiple journals.

    But upon finishing this tranche of research, Hassan realized that it was insufficient simply to study the structure of the state. “Understanding the role of new administrative structures for politics, development, and governance fundamentally requires that we understand who the government has put in charge of them,” she says. Among her insights:

    “The president’s office knows a lot of these administrators, and thinks about their strengths, limitations, and fit within a community,” says Hassan. Some administrators served the purposes of the central government by setting up water irrigation projects or building a new school. But in other villages, the state chose administrators who could act “much more coercively, ignoring development needs, throwing youth who supported the opposition into jail, and spending resources exclusively on policing.”

    Hassan’s work showed that in communities characterized by strong political opposition, “the local administration was always more coercive, regardless of an elected or autocratic president,” she says. Notably, the tenures of such officials proved shorter than those of their peers. “Once administrators get to know a community — going to church and the market with residents — it’s hard to coerce them,” explains Hassan.

    These short tenures come with costs, she notes: “Spending significant time in a station is useful for development, because you know exactly whom to hire if you want to build a school or get something done efficiently.” Politicizing these assignments undermines efforts at delivery of services and, more broadly, economic improvement nationwide. “Regimes that are more invested in retaining power must devote resources to establishing and maintaining control, resources that could otherwise be used for development and the welfare of citizens,” she says.

    Hassan wove together her research covering three presidents over a 50-year period, in the book, “Regime Threats and State Solutions: Bureaucratic Loyalty and Embeddedness in Kenya” (2020, Cambridge University Press), named a Foreign Affairs Best Book of 2020.

    Sudanese roots

    The role of the state in fulfilling the needs of its citizens has long fascinated Hassan. Her grandfather, who had served as Sudan’s ambassador to the USSR, talked to her about the advantages of a centralized government “that allocated resources to reduce inequality,” she says.

    Politics often dominated the conversation in gatherings of Hassan’s family and friends. Her parents immigrated to northern Virginia when she was very young, and many relatives joined them, part of a steady flow of Sudanese fleeing political turmoil and oppression.

    “A lot of people had expected more from the Sudanese state after independence and didn’t get it,” she says. “People had hopes for what the government could and should do.”

    Hassan’s Sudanese roots and ongoing connection to the Sudanese community have shaped her academic interests and goals. At the University of Virginia, she gravitated toward history and economics classes. But it was her time at the Ralph Bunche Summer institute that perhaps proved most pivotal in her journey. This five-week intensive program is offered by the American Political Science Association to introduce underrepresented undergraduate students to doctoral studies. “It was really compelling in this program to think rigorously about all the political ideas I’d heard as I was growing up, and find ways to challenge some assertions empirically,” she says.

    Regime change and civil society

    At Harvard, Hassan first set out to focus on Sudan for her doctoral program. “There wasn’t much scholarship on the country, and what there was lacked rigor,” she says. “That was something that needed to change.” But she decided to postpone this goal after realizing that she might be vulnerable as a student conducting field research there. She landed instead in Kenya, where she honed her interviewing and data collection skills.

    Today, empowered by her prior work, she has returned to Sudan. “I felt that the popular uprising in Sudan and ousting of the Islamist regime in 2019 should be documented and analyzed,” she says. “It was incredible that hundreds of thousands, if not millions, acted collectively to uproot a dictator, in the face of brutal violence from the state.”But “democracy is still uncertain there,” says Hassan. The broad coalition behind regime change “doesn’t know how to govern because different people and different sectors of society have different ideas about what democratic Sudan should look like,” she says. “Overthrowing an autocratic regime and having civil society come together to figure out what’s going to replace it require different things, and it’s unclear if a movement that accomplishes the first is well-suited to do the second.”

    Hassan believes that in order to create lasting democratization, “you need the hard work of building organizations, developing ways in which members learn to compromise among themselves, and make decisions and rules for how to move forward.”

    Hassan is enjoying the fall semester and teaching courses on autocracy and authoritarian regimes. She is excited as well about developing her work on African efforts at democratic mobilization in a political science department she describes as “policy-forward.”

    Over time, she hopes to connect with Institute scholars in the hard sciences to think about other challenges these nations are facing, such as climate change. “It’s really hot in Sudan, and it may be one of the first countries to become completely uninhabitable,” she says. “I’d like to explore strategies for growing crops differently or managing the exceedingly scarce resource of water, and figure out what kind of political discussions will be necessary to implement any changes. It is really critical to think about these problems in an interdisciplinary way.” More