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    Using nature’s structures in wooden buildings

    Concern about climate change has focused significant attention on the buildings sector, in particular on the extraction and processing of construction materials. The concrete and steel industries together are responsible for as much as 15 percent of global carbon dioxide emissions. In contrast, wood provides a natural form of carbon sequestration, so there’s a move to use timber instead. Indeed, some countries are calling for public buildings to be made at least partly from timber, and large-scale timber buildings have been appearing around the world.

    Observing those trends, Caitlin Mueller ’07, SM ’14, PhD ’14, an associate professor of architecture and of civil and environmental engineering in the Building Technology Program at MIT, sees an opportunity for further sustainability gains. As the timber industry seeks to produce wooden replacements for traditional concrete and steel elements, the focus is on harvesting the straight sections of trees. Irregular sections such as knots and forks are turned into pellets and burned, or ground up to make garden mulch, which will decompose within a few years; both approaches release the carbon trapped in the wood to the atmosphere.

    For the past four years, Mueller and her Digital Structures research group have been developing a strategy for “upcycling” those waste materials by using them in construction — not as cladding or finishes aimed at improving appearance, but as structural components. “The greatest value you can give to a material is to give it a load-bearing role in a structure,” she says. But when builders use virgin materials, those structural components are the most emissions-intensive parts of buildings due to their large volume of high-strength materials. Using upcycled materials in place of those high-carbon systems is therefore especially impactful in reducing emissions.

    Mueller and her team focus on tree forks — that is, spots where the trunk or branch of a tree divides in two, forming a Y-shaped piece. In architectural drawings, there are many similar Y-shaped nodes where straight elements come together. In such cases, those units must be strong enough to support critical loads.

    “Tree forks are naturally engineered structural connections that work as cantilevers in trees, which means that they have the potential to transfer force very efficiently thanks to their internal fiber structure,” says Mueller. “If you take a tree fork and slice it down the middle, you see an unbelievable network of fibers that are intertwining to create these often three-dimensional load transfer points in a tree. We’re starting to do the same thing using 3D printing, but we’re nowhere near what nature does in terms of complex fiber orientation and geometry.”

    She and her team have developed a five-step “design-to-fabrication workflow” that combines natural structures such as tree forks with the digital and computational tools now used in architectural design. While there’s long been a “craft” movement to use natural wood in railings and decorative features, the use of computational tools makes it possible to use wood in structural roles — without excessive cutting, which is costly and may compromise the natural geometry and internal grain structure of the wood.

    Given the wide use of digital tools by today’s architects, Mueller believes that her approach is “at least potentially scalable and potentially achievable within our industrialized materials processing systems.” In addition, by combining tree forks with digital design tools, the novel approach can also support the trend among architects to explore new forms. “Many iconic buildings built in the past two decades have unexpected shapes,” says Mueller. “Tree branches have a very specific geometry that sometimes lends itself to an irregular or nonstandard architectural form — driven not by some arbitrary algorithm but by the material itself.”

    Step 0: Find a source, set goals

    Before starting their design-to-fabrication process, the researchers needed to locate a source of tree forks. Mueller found help in the Urban Forestry Division of the City of Somerville, Massachusetts, which maintains a digital inventory of more than 2,000 street trees — including more than 20 species — and records information about the location, approximate trunk diameter, and condition of each tree.

    With permission from the forestry division, the team was on hand in 2018 when a large group of trees was cut down near the site of the new Somerville High School. Among the heavy equipment on site was a chipper, poised to turn all the waste wood into mulch. Instead, the workers obligingly put the waste wood into the researchers’ truck to be brought to MIT.

    In their project, the MIT team sought not only to upcycle that waste material but also to use it to create a structure that would be valued by the public. “Where I live, the city has had to take down a lot of trees due to damage from an invasive species of beetle,” Mueller explains. “People get really upset — understandably. Trees are an important part of the urban fabric, providing shade and beauty.” She and her team hoped to reduce that animosity by “reinstalling the removed trees in the form of a new functional structure that would recreate the atmosphere and spatial experience previously provided by the felled trees.”

    With their source and goals identified, the researchers were ready to demonstrate the five steps in their design-to-fabrication workflow for making spatial structures using an inventory of tree forks.

    Step 1: Create a digital material library

    The first task was to turn their collection of tree forks into a digital library. They began by cutting off excess material to produce isolated tree forks. They then created a 3D scan of each fork. Mueller notes that as a result of recent progress in photogrammetry (measuring objects using photographs) and 3D scanning, they could create high-resolution digital representations of the individual tree forks with relatively inexpensive equipment, even using apps that run on a typical smartphone.

    In the digital library, each fork is represented by a “skeletonized” version showing three straight bars coming together at a point. The relative geometry and orientation of the branches are of particular interest because they determine the internal fiber orientation that gives the component its strength.

    Step 2: Find the best match between the initial design and the material library

    Like a tree, a typical architectural design is filled with Y-shaped nodes where three straight elements meet up to support a critical load. The goal was therefore to match the tree forks in the material library with the nodes in a sample architectural design.

    First, the researchers developed a “mismatch metric” for quantifying how well the geometries of a particular tree fork aligned with a given design node. “We’re trying to line up the straight elements in the structure with where the branches originally were in the tree,” explains Mueller. “That gives us the optimal orientation for load transfer and maximizes use of the inherent strength of the wood fiber.” The poorer the alignment, the higher the mismatch metric.

    The goal was to get the best overall distribution of all the tree forks among the nodes in the target design. Therefore, the researchers needed to try different fork-to-node distributions and, for each distribution, add up the individual fork-to-node mismatch errors to generate an overall, or global, matching score. The distribution with the best matching score would produce the most structurally efficient use of the total tree fork inventory.

    Since performing that process manually would take far too long to be practical, they turned to the “Hungarian algorithm,” a technique developed in 1955 for solving such problems. “The brilliance of the algorithm is solving that [matching] problem very quickly,” Mueller says. She notes that it’s a very general-use algorithm. “It’s used for things like marriage match-making. It can be used any time you have two collections of things that you’re trying to find unique matches between. So, we definitely didn’t invent the algorithm, but we were the first to identify that it could be used for this problem.”

    The researchers performed repeated tests to show possible distributions of the tree forks in their inventory and found that the matching score improved as the number of forks available in the material library increased — up to a point. In general, the researchers concluded that the mismatch score was lowest, and thus best, when there were about three times as many forks in the material library as there were nodes in the target design.

    Step 3: Balance designer intention with structural performance

    The next step in the process was to incorporate the intention or preference of the designer. To permit that flexibility, each design includes a limited number of critical parameters, such as bar length and bending strain. Using those parameters, the designer can manually change the overall shape, or geometry, of the design or can use an algorithm that automatically changes, or “morphs,” the geometry. And every time the design geometry changes, the Hungarian algorithm recalculates the optimal fork-to-node matching.

    “Because the Hungarian algorithm is extremely fast, all the morphing and the design updating can be really fluid,” notes Mueller. In addition, any change to a new geometry is followed by a structural analysis that checks the deflections, strain energy, and other performance measures of the structure. On occasion, the automatically generated design that yields the best matching score may deviate far from the designer’s initial intention. In such cases, an alternative solution can be found that satisfactorily balances the design intention with a low matching score.

    Step 4: Automatically generate the machine code for fast cutting

    When the structural geometry and distribution of tree forks have been finalized, it’s time to think about actually building the structure. To simplify assembly and maintenance, the researchers prepare the tree forks by recutting their end faces to better match adjoining straight timbers and cutting off any remaining bark to reduce susceptibility to rot and fire.

    To guide that process, they developed a custom algorithm that automatically computes the cuts needed to make a given tree fork fit into its assigned node and to strip off the bark. The goal is to remove as little material as possible but also to avoid a complex, time-consuming machining process. “If we make too few cuts, we’ll cut off too much of the critical structural material. But we don’t want to make a million tiny cuts because it will take forever,” Mueller explains.

    The team uses facilities at the Autodesk Boston Technology Center Build Space, where the robots are far larger than any at MIT and the processing is all automated. To prepare each tree fork, they mount it on a robotic arm that pushes the joint through a traditional band saw in different orientations, guided by computer-generated instructions. The robot also mills all the holes for the structural connections. “That’s helpful because it ensures that everything is aligned the way you expect it to be,” says Mueller.

    Step 5: Assemble the available forks and linear elements to build the structure

    The final step is to assemble the structure. The tree-fork-based joints are all irregular, and combining them with the precut, straight wooden elements could be difficult. However, they’re all labeled. “All the information for the geometry is embedded in the joint, so the assembly process is really low-tech,” says Mueller. “It’s like a child’s toy set. You just follow the instructions on the joints to put all the pieces together.”

    They installed their final structure temporarily on the MIT campus, but Mueller notes that it was only a portion of the structure they plan to eventually build. “It had 12 nodes that we designed and fabricated using our process,” she says, adding that the team’s work was “a little interrupted by the pandemic.” As activity on campus resumes, the researchers plan to finish designing and building the complete structure, which will include about 40 nodes and will be installed as an outdoor pavilion on the site of the felled trees in Somerville.

    In addition, they will continue their research. Plans include working with larger material libraries, some with multibranch forks, and replacing their 3D-scanning technique with computerized tomography scanning technologies that can automatically generate a detailed geometric representation of a tree fork, including its precise fiber orientation and density. And in a parallel project, they’ve been exploring using their process with other sources of materials, with one case study focusing on using material from a demolished wood-framed house to construct more than a dozen geodesic domes.

    To Mueller, the work to date already provides new guidance for the architectural design process. With digital tools, it has become easy for architects to analyze the embodied carbon or future energy use of a design option. “Now we have a new metric of performance: How well am I using available resources?” she says. “With the Hungarian algorithm, we can compute that metric basically in real time, so we can work rapidly and creatively with that as another input to the design process.”

    This research was supported by MIT’s School of Architecture and Planning via the HASS Award.

    This article appears in the Autumn 2021 issue of Energy Futures, the magazine of the MIT Energy Initiative. More

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    New maps show airplane contrails over the U.S. dropped steeply in 2020

    As Covid-19’s initial wave crested around the world, travel restrictions and a drop in passengers led to a record number of grounded flights in 2020. The air travel reduction cleared the skies of not just jets but also the fluffy white contrails they produce high in the atmosphere.

    MIT engineers have mapped the contrails that were generated over the United States in 2020, and compared the results to prepandemic years. They found that on any given day in 2018, and again in 2019, contrails covered a total area equal to Massachusetts and Connecticut combined. In 2020, this contrail coverage shrank by about 20 percent, mirroring a similar drop in U.S. flights.  

    While 2020’s contrail dip may not be surprising, the findings are proof that the team’s mapping technique works. Their study marks the first time researchers have captured the fine and ephemeral details of contrails over a large continental scale.

    Now, the researchers are applying the technique to predict where in the atmosphere contrails are likely to form. The cloud-like formations are known to play a significant role in aviation-related global warming. The team is working with major airlines to forecast regions in the atmosphere where contrails may form, and to reroute planes around these regions to minimize contrail production.

    “This kind of technology can help divert planes to prevent contrails, in real time,” says Steven Barrett, professor and associate head of MIT’s Department of Aeronautics and Astronautics. “There’s an unusual opportunity to halve aviation’s climate impact by eliminating most of the contrails produced today.”

    Barrett and his colleagues have published their results today in the journal Environmental Research Letters. His co-authors at MIT include graduate student Vincent Meijer, former graduate student Luke Kulik, research scientists Sebastian Eastham, Florian Allroggen, and Raymond Speth, and LIDS Director and professor Sertac Karaman.

    Trail training

    About half of the aviation industry’s contribution to global warming comes directly from planes’ carbon dioxide emissions. The other half is thought to be a consequence of their contrails. The signature white tails are produced when a plane’s hot, humid exhaust mixes with cool humid air high in the atmosphere. Emitted in thin lines, contrails quickly spread out and can act as blankets that trap the Earth’s outgoing heat.

    While a single contrail may not have much of a warming effect, taken together contrails have a significant impact. But the estimates of this effect are uncertain and based on computer modeling as well as limited satellite data. What’s more, traditional computer vision algorithms that analyze contrail data have a hard time discerning the wispy tails from natural clouds.

    To precisely pick out and track contrails over a large scale, the MIT team looked to images taken by NASA’s GOES-16, a geostationary satellite that hovers over the same swath of the Earth, including the United States, taking continuous, high-resolution images.

    The team first obtained about 100 images taken by the satellite, and trained a set of people to interpret remote sensing data and label each image’s pixel as either part of a contrail or not. They used this labeled dataset to train a computer-vision algorithm to discern a contrail from a cloud or other image feature.

    The researchers then ran the algorithm on about 100,000 satellite images, amounting to nearly 6 trillion pixels, each pixel representing an area of about 2 square kilometers. The images covered the contiguous U.S., along with parts of Canada and Mexico, and were taken about every 15 minutes, between Jan. 1, 2018, and Dec. 31, 2020.

    The algorithm automatically classified each pixel as either a contrail or not a contrail, and generated daily maps of contrails over the United States. These maps mirrored the major flight paths of most U.S. airlines, with some notable differences. For instance, contrail “holes” appeared around major airports, which reflects the fact that planes landing and taking off around airports are generally not high enough in the atmosphere for contrails to form.

    “The algorithm knows nothing about where planes fly, and yet when processing the satellite imagery, it resulted in recognizable flight routes,” Barrett says. “That’s one piece of evidence that says this method really does capture contrails over a large scale.”

    Cloudy patterns

    Based on the algorithm’s maps, the researchers calculated the total area covered each day by contrails in the US. On an average day in 2018 and in 2019, U.S. contrails took up about 43,000 square kilometers. This coverage dropped by 20 percent in March of 2020 as the pandemic set in. From then on, contrails slowly reappeared as air travel resumed through the year.

    The team also observed daily and seasonal patterns. In general, contrails appeared to peak in the morning and decline in the afternoon. This may be a training artifact: As natural cirrus clouds are more likely to form in the afternoon, the algorithm may have trouble discerning contrails amid the clouds later in the day. But it might also be an important indication about when contrails form most. Contrails also peaked in late winter and early spring, when more of the air is naturally colder and more conducive for contrail formation.

    The team has now adapted the technique to predict where contrails are likely to form in real time. Avoiding these regions, Barrett says, could take a significant, almost immediate chunk out of aviation’s global warming contribution.  

    “Most measures to make aviation sustainable take a long time,” Barrett says. “(Contrail avoidance) could be accomplished in a few years, because it requires small changes to how aircraft are flown, with existing airplanes and observational technology. It’s a near-term way of reducing aviation’s warming by about half.”

    The team is now working towards this objective of large-scale contrail avoidance using realtime satellite observations.

    This research was supported in part by NASA and the MIT Environmental Solutions Initiative. More

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    3 Questions: Anuradha Annaswamy on building smart infrastructures

    Much of Anuradha Annaswamy’s research hinges on uncertainty. How does cloudy weather affect a grid powered by solar energy? How do we ensure that electricity is delivered to the consumer if a grid is powered by wind and the wind does not blow? What’s the best course of action if a bird hits a plane engine on takeoff? How can you predict the behavior of a cyber attacker?

    A senior research scientist in MIT’s Department of Mechanical Engineering, Annaswamy spends most of her research time dealing with decision-making under uncertainty. Designing smart infrastructures that are resilient to uncertainty can lead to safer, more reliable systems, she says.

    Annaswamy serves as the director of MIT’s Active Adaptive Control Laboratory. A world-leading expert in adaptive control theory, she was named president of the Institute of Electrical and Electronics Engineers Control Systems Society for 2020. Her team uses adaptive control and optimization to account for various uncertainties and anomalies in autonomous systems. In particular, they are developing smart infrastructures in the energy and transportation sectors.

    Using a combination of control theory, cognitive science, economic modeling, and cyber-physical systems, Annaswamy and her team have designed intelligent systems that could someday transform the way we travel and consume energy. Their research includes a diverse range of topics such as safer autopilot systems on airplanes, the efficient dispatch of resources in electrical grids, better ride-sharing services, and price-responsive railway systems.

    In a recent interview, Annaswamy spoke about how these smart systems could help support a safer and more sustainable future.

    Q: How is your team using adaptive control to make air travel safer?

    A: We want to develop an advanced autopilot system that can safely recover the airplane in the event of a severe anomaly — such as the wing becoming damaged mid-flight, or a bird flying into the engine. In the airplane, you have a pilot and autopilot to make decisions. We’re asking: How do you combine those two decision-makers?

    The answer we landed on was developing a shared pilot-autopilot control architecture. We collaborated with David Woods, an expert in cognitive engineering at The Ohio State University, to develop an intelligent system that takes the pilot’s behavior into account. For example, all humans have something known as “capacity for maneuver” and “graceful command degradation” that inform how we react in the face of adversity. Using mathematical models of pilot behavior, we proposed a shared control architecture where the pilot and the autopilot work together to make an intelligent decision on how to react in the face of uncertainties. In this system, the pilot reports the anomaly to an adaptive autopilot system that ensures resilient flight control.

    Q: How does your research on adaptive control fit into the concept of smart cities?

    A: Smart cities are an interesting way we can use intelligent systems to promote sustainability. Our team is looking at ride-sharing services in particular. Services like Uber and Lyft have provided new transportation options, but their impact on the carbon footprint has to be considered. We’re looking at developing a system where the number of passenger-miles per unit of energy is maximized through something called “shared mobility on demand services.” Using the alternating minimization approach, we’ve developed an algorithm that can determine the optimal route for multiple passengers traveling to various destinations.

    As with the pilot-autopilot dynamic, human behavior is at play here. In sociology there is an interesting concept of behavioral dynamics known as Prospect Theory. If we give passengers options with regards to which route their shared ride service will take, we are empowering them with free will to accept or reject a route. Prospect Theory shows that if you can use pricing as an incentive, people are much more loss-averse so they would be willing to walk a bit extra or wait a few minutes longer to join a low-cost ride with an optimized route. If everyone utilized a system like this, the carbon footprint of ride-sharing services could decrease substantially.

    Q: What other ways are you using intelligent systems to promote sustainability?

    A: Renewable energy and sustainability are huge drivers for our research. To enable a world where all of our energy is coming from renewable sources like solar or wind, we need to develop a smart grid that can account for the fact that the sun isn’t always shining and wind isn’t always blowing. These uncertainties are the biggest hurdles to achieving an all-renewable grid. Of course, there are many technologies being developed for batteries that can help store renewable energy, but we are taking a different approach.

    We have created algorithms that can optimally schedule distributed energy resources within the grid — this includes making decisions on when to use onsite generators, how to operate storage devices, and when to call upon demand response technologies, all in response to the economics of using such resources and their physical constraints. If we can develop an interconnected smart grid where, for example, the air conditioning setting in a house is set to 72 degrees instead of 69 degrees automatically when demand is high, there could be a substantial savings in energy usage without impacting human comfort. In one of our studies, we applied a distributed proximal atomic coordination algorithm to the grid in Tokyo to demonstrate how this intelligent system could account for the uncertainties present in a grid powered by renewable resources. More

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    SMART researchers develop method for early detection of bacterial infection in crops

    Researchers from the Disruptive and Sustainable Technologies for Agricultural Precision (DiSTAP) Interdisciplinary Research Group (IRG) ofSingapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, and their local collaborators from Temasek Life Sciences Laboratory (TLL), have developed a rapid Raman spectroscopy-based method for detecting and quantifying early bacterial infection in crops. The Raman spectral biomarkers and diagnostic algorithm enable the noninvasive and early diagnosis of bacterial infections in crop plants, which can be critical for the progress of plant disease management and agricultural productivity.

    Due to the increasing demand for global food supply and security, there is a growing need to improve agricultural production systems and increase crop productivity. Globally, bacterial pathogen infection in crop plants is one of the major contributors to agricultural yield losses. Climate change also adds to the problem by accelerating the spread of plant diseases. Hence, developing methods for rapid and early detection of pathogen-infected crops is important to improve plant disease management and reduce crop loss.

    The breakthrough by SMART and TLL researchers offers a faster and more accurate method to detect bacterial infection in crop plants at an earlier stage, as compared to existing techniques. The new results appear in a paper titled “Rapid detection and quantification of plant innate immunity response using Raman spectroscopy” published in the journal Frontiers in Plant Science.

    “The early detection of pathogen-infected crop plants is a significant step to improve plant disease management,” says Chua Nam Hai, DiSTAP co-lead principal investigator, professor, TLL deputy chair, and co-corresponding author. “It will allow the fast and selective removal of pathogen load and curb the further spread of disease to other neighboring crops.”

    Traditionally, plant disease diagnosis involves a simple visual inspection of plants for disease symptoms and severity. “Visual inspection methods are often ineffective, as disease symptoms usually manifest only at relatively later stages of infection, when the pathogen load is already high and reparative measures are limited. Hence, new methods are required for rapid and early detection of bacterial infection. The idea would be akin to having medical tests to identify human diseases at an early stage, instead of waiting for visual symptoms to show, so that early intervention or treatment can be applied,” says MIT Professor Rajeev Ram, who is a DiSTAP principal investigator and co-corresponding author on the paper.

    While existing techniques, such as current molecular detection methods, can detect bacterial infection in plants, they are often limited in their use. Molecular detection methods largely depend on the availability of pathogen-specific gene sequences or antibodies to identify bacterial infection in crops; the implementation is also time-consuming and nonadaptable for on-site field application due to the high cost and bulky equipment required, making it impractical for use in agricultural farms.

    “At DiSTAP, we have developed a quantitative Raman spectroscopy-based algorithm that can help farmers to identify bacterial infection rapidly. The developed diagnostic algorithm makes use of Raman spectral biomarkers and can be easily implemented in cloud-based computing and prediction platforms. It is more effective than existing techniques as it enables accurate identification and early detection of bacterial infection, both of which are crucial to saving crop plants that would otherwise be destroyed,” explains Gajendra Pratap Singh, scientific director and principal investigator at DiSTAP and co-lead author.

    A portable Raman system can be used on farms and provides farmers with an accurate and simple yes-or-no response when used to test for the presence of bacterial infections in crops. The development of this rapid and noninvasive method could improve plant disease management and have a transformative impact on agricultural farms by efficiently reducing agricultural yield loss and increasing productivity.

    “Using the diagnostic algorithm method, we experimented on several edible plants such as choy sum,” says DiSTAP and TLL principal investigator and co-corresponding author Rajani Sarojam. “The results showed that the Raman spectroscopy-based method can swiftly detect and quantify innate immunity response in plants infected with bacterial pathogens. We believe that this technology will be beneficial for agricultural farms to increase their productivity by reducing their yield loss due to plant diseases.”

    The researchers are currently working on the development of high-throughput, custom-made portable or hand-held Raman spectrometers that will allow Raman spectral analysis to be quickly and easily performed on field-grown crops.

    SMART and TLL developed and discovered the diagnostic algorithm and Raman spectral biomarkers. TLL also confirmed and validated the detection method through mutant plants. The research is carried out by SMART and supported by the National Research Foundation of Singapore under its Campus for Research Excellence And Technological Enterprise (CREATE) program.

    SMART was established by MIT and the NRF in 2007. The first entity in CREATE developed by NRF, SMART serves as an intellectual and innovation hub for research interactions between MIT and Singapore, undertaking cutting-edge research projects in areas of interest to both Singapore and MIT. SMART currently comprises an Innovation Center and five IRGs: Antimicrobial Resistance, Critical Analytics for Manufacturing Personalized-Medicine, DiSTAP, Future Urban Mobility, and Low Energy Electronic Systems. SMART research is funded by the NRF under the CREATE program.

    Led by Professor Michael Strano of MIT and Professor Chua Nam Hai of Temasek Lifesciences Laboratory, the DiSTAP program addresses deep problems in food production in Singapore and the world by developing a suite of impactful and novel analytical, genetic, and biomaterial technologies. The goal is to fundamentally change how plant biosynthetic pathways are discovered, monitored, engineered, and ultimately translated to meet the global demand for food and nutrients. Scientists from MIT, TTL, Nanyang Technological University, and National University of Singapore are collaboratively developing new tools for the continuous measurement of important plant metabolites and hormones for novel discovery, deeper understanding and control of plant biosynthetic pathways in ways not yet possible, especially in the context of green leafy vegetables; leveraging these new techniques to engineer plants with highly desirable properties for global food security, including high-yield density production, and drought and pathogen resistance; and applying these technologies to improve urban farming. More

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    Design’s new frontier

    In the 1960s, the advent of computer-aided design (CAD) sparked a revolution in design. For his PhD thesis in 1963, MIT Professor Ivan Sutherland developed Sketchpad, a game-changing software program that enabled users to draw, move, and resize shapes on a computer. Over the course of the next few decades, CAD software reshaped how everything from consumer products to buildings and airplanes were designed.

    “CAD was part of the first wave in computing in design. The ability of researchers and practitioners to represent and model designs using computers was a major breakthrough and still is one of the biggest outcomes of design research, in my opinion,” says Maria Yang, Gail E. Kendall Professor and director of MIT’s Ideation Lab.

    Innovations in 3D printing during the 1980s and 1990s expanded CAD’s capabilities beyond traditional injection molding and casting methods, providing designers even more flexibility. Designers could sketch, ideate, and develop prototypes or models faster and more efficiently. Meanwhile, with the push of a button, software like that developed by Professor Emeritus David Gossard of MIT’s CAD Lab could solve equations simultaneously to produce a new geometry on the fly.

    In recent years, mechanical engineers have expanded the computing tools they use to ideate, design, and prototype. More sophisticated algorithms and the explosion of machine learning and artificial intelligence technologies have sparked a second revolution in design engineering.

    Researchers and faculty at MIT’s Department of Mechanical Engineering are utilizing these technologies to re-imagine how the products, systems, and infrastructures we use are designed. These researchers are at the forefront of the new frontier in design.

    Computational design

    Faez Ahmed wants to reinvent the wheel, or at least the bicycle wheel. He and his team at MIT’s Design Computation & Digital Engineering Lab (DeCoDE) use an artificial intelligence-driven design method that can generate entirely novel and improved designs for a range of products — including the traditional bicycle. They create advanced computational methods to blend human-driven design with simulation-based design.

    “The focus of our DeCoDE lab is computational design. We are looking at how we can create machine learning and AI algorithms to help us discover new designs that are optimized based on specific performance parameters,” says Ahmed, an assistant professor of mechanical engineering at MIT.

    For their work using AI-driven design for bicycles, Ahmed and his collaborator Professor Daniel Frey wanted to make it easier to design customizable bicycles, and by extension, encourage more people to use bicycles over transportation methods that emit greenhouse gases.

    To start, the group gathered a dataset of 4,500 bicycle designs. Using this massive dataset, they tested the limits of what machine learning could do. First, they developed algorithms to group bicycles that looked similar together and explore the design space. They then created machine learning models that could successfully predict what components are key in identifying a bicycle style, such as a road bike versus a mountain bike.

    Once the algorithms were good enough at identifying bicycle designs and parts, the team proposed novel machine learning tools that could use this data to create a unique and creative design for a bicycle based on certain performance parameters and rider dimensions.

    Ahmed used a generative adversarial network — or GAN — as the basis of this model. GAN models utilize neural networks that can create new designs based on vast amounts of data. However, using GAN models alone would result in homogeneous designs that lack novelty and can’t be assessed in terms of performance. To address these issues in design problems, Ahmed has developed a new method which he calls “PaDGAN,” performance augmented diverse GAN.

    “When we apply this type of model, what we see is that we can get large improvements in the diversity, quality, as well as novelty of the designs,” Ahmed explains.

    Using this approach, Ahmed’s team developed an open-source computational design tool for bicycles freely available on their lab website. They hope to further develop a set of generalizable tools that can be used across industries and products.

    Longer term, Ahmed has his sights set on loftier goals. He hopes the computational design tools he develops could lead to “design democratization,” putting more power in the hands of the end user.

    “With these algorithms, you can have more individualization where the algorithm assists a customer in understanding their needs and helps them create a product that satisfies their exact requirements,” he adds.

    Using algorithms to democratize the design process is a goal shared by Stefanie Mueller, an associate professor in electrical engineering and computer science and mechanical engineering.

    Personal fabrication

    Platforms like Instagram give users the freedom to instantly edit their photographs or videos using filters. In one click, users can alter the palette, tone, and brightness of their content by applying filters that range from bold colors to sepia-toned or black-and-white. Mueller, X-Window Consortium Career Development Professor, wants to bring this concept of the Instagram filter to the physical world.

    “We want to explore how digital capabilities can be applied to tangible objects. Our goal is to bring reprogrammable appearance to the physical world,” explains Mueller, director of the HCI Engineering Group based out of MIT’s Computer Science and Artificial Intelligence Laboratory.

    Mueller’s team utilizes a combination of smart materials, optics, and computation to advance personal fabrication technologies that would allow end users to alter the design and appearance of the products they own. They tested this concept in a project they dubbed “Photo-Chromeleon.”

    First, a mix of photochromic cyan, magenta, and yellow dies are airbrushed onto an object — in this instance, a 3D sculpture of a chameleon. Using software they developed, the team sketches the exact color pattern they want to achieve on the object itself. An ultraviolet light shines on the object to activate the dyes.

    To actually create the physical pattern on the object, Mueller has developed an optimization algorithm to use alongside a normal office projector outfitted with red, green, and blue LED lights. These lights shine on specific pixels on the object for a given period of time to physically change the makeup of the photochromic pigments.

    “This fancy algorithm tells us exactly how long we have to shine the red, green, and blue light on every single pixel of an object to get the exact pattern we’ve programmed in our software,” says Mueller.

    Giving this freedom to the end user enables limitless possibilities. Mueller’s team has applied this technology to iPhone cases, shoes, and even cars. In the case of shoes, Mueller envisions a shoebox embedded with UV and LED light projectors. Users could put their shoes in the box overnight and the next day have a pair of shoes in a completely new pattern.

    Mueller wants to expand her personal fabrication methods to the clothes we wear. Rather than utilize the light projection technique developed in the PhotoChromeleon project, her team is exploring the possibility of weaving LEDs directly into clothing fibers, allowing people to change their shirt’s appearance as they wear it. These personal fabrication technologies could completely alter consumer habits.

    “It’s very interesting for me to think about how these computational techniques will change product design on a high level,” adds Mueller. “In the future, a consumer could buy a blank iPhone case and update the design on a weekly or daily basis.”

    Computational fluid dynamics and participatory design

    Another team of mechanical engineers, including Sili Deng, the Brit (1961) & Alex (1949) d’Arbeloff Career Development Professor, are developing a different kind of design tool that could have a large impact on individuals in low- and middle-income countries across the world.

    As Deng walked down the hallway of Building 1 on MIT’s campus, a monitor playing a video caught her eye. The video featured work done by mechanical engineers and MIT D-Lab on developing cleaner burning briquettes for cookstoves in Uganda. Deng immediately knew she wanted to get involved.

    “As a combustion scientist, I’ve always wanted to work on such a tangible real-world problem, but the field of combustion tends to focus more heavily on the academic side of things,” explains Deng.

    After reaching out to colleagues in MIT D-Lab, Deng joined a collaborative effort to develop a new cookstove design tool for the 3 billion people across the world who burn solid fuels to cook and heat their homes. These stoves often emit soot and carbon monoxide, leading not only to millions of deaths each year, but also worsening the world’s greenhouse gas emission problem.

    The team is taking a three-pronged approach to developing this solution, using a combination of participatory design, physical modeling, and experimental validation to create a tool that will lead to the production of high-performing, low-cost energy products.

    Deng and her team in the Deng Energy and Nanotechnology Group use physics-based modeling for the combustion and emission process in cookstoves.

    “My team is focused on computational fluid dynamics. We use computational and numerical studies to understand the flow field where the fuel is burned and releases heat,” says Deng.

    These flow mechanics are crucial to understanding how to minimize heat loss and make cookstoves more efficient, as well as learning how dangerous pollutants are formed and released in the process.

    Using computational methods, Deng’s team performs three-dimensional simulations of the complex chemistry and transport coupling at play in the combustion and emission processes. They then use these simulations to build a combustion model for how fuel is burned and a pollution model that predicts carbon monoxide emissions.

    Deng’s models are used by a group led by Daniel Sweeney in MIT D-Lab to test the experimental validation in prototypes of stoves. Finally, Professor Maria Yang uses participatory design methods to integrate user feedback, ensuring the design tool can actually be used by people across the world.

    The end goal for this collaborative team is to not only provide local manufacturers with a prototype they could produce themselves, but to also provide them with a tool that can tweak the design based on local needs and available materials.

    Deng sees wide-ranging applications for the computational fluid dynamics her team is developing.

    “We see an opportunity to use physics-based modeling, augmented with a machine learning approach, to come up with chemical models for practical fuels that help us better understand combustion. Therefore, we can design new methods to minimize carbon emissions,” she adds.

    While Deng is utilizing simulations and machine learning at the molecular level to improve designs, others are taking a more macro approach.

    Designing intelligent systems

    When it comes to intelligent design, Navid Azizan thinks big. He hopes to help create future intelligent systems that are capable of making decisions autonomously by using the enormous amounts of data emerging from the physical world. From smart robots and autonomous vehicles to smart power grids and smart cities, Azizan focuses on the analysis, design, and control of intelligent systems.

    Achieving such massive feats takes a truly interdisciplinary approach that draws upon various fields such as machine learning, dynamical systems, control, optimization, statistics, and network science, among others.

    “Developing intelligent systems is a multifaceted problem, and it really requires a confluence of disciplines,” says Azizan, assistant professor of mechanical engineering with a dual appointment in MIT’s Institute for Data, Systems, and Society (IDSS). “To create such systems, we need to go beyond standard approaches to machine learning, such as those commonly used in computer vision, and devise algorithms that can enable safe, efficient, real-time decision-making for physical systems.”

    For robot control to work in the complex dynamic environments that arise in the real world, real-time adaptation is key. If, for example, an autonomous vehicle is going to drive in icy conditions or a drone is operating in windy conditions, they need to be able to adapt to their new environment quickly.

    To address this challenge, Azizan and his collaborators at MIT and Stanford University have developed a new algorithm that combines adaptive control, a powerful methodology from control theory, with meta learning, a new machine learning paradigm.

    “This ‘control-oriented’ learning approach outperforms the existing ‘regression-oriented’ methods, which are mostly focused on just fitting the data, by a wide margin,” says Azizan.

    Another critical aspect of deploying machine learning algorithms in physical systems that Azizan and his team hope to address is safety. Deep neural networks are a crucial part of autonomous systems. They are used for interpreting complex visual inputs and making data-driven predictions of future behavior in real time. However, Azizan urges caution.

    “These deep neural networks are only as good as their training data, and their predictions can often be untrustworthy in scenarios not covered by their training data,” he says. Making decisions based on such untrustworthy predictions could lead to fatal accidents in autonomous vehicles or other safety-critical systems.

    To avoid these potentially catastrophic events, Azizan proposes that it is imperative to equip neural networks with a measure of their uncertainty. When the uncertainty is high, they can then be switched to a “safe policy.”

    In pursuit of this goal, Azizan and his collaborators have developed a new algorithm known as SCOD — Sketching Curvature of Out-of-Distribution Detection. This framework could be embedded within any deep neural network to equip them with a measure of their uncertainty.

    “This algorithm is model-agnostic and can be applied to neural networks used in various kinds of autonomous systems, whether it’s drones, vehicles, or robots,” says Azizan.

    Azizan hopes to continue working on algorithms for even larger-scale systems. He and his team are designing efficient algorithms to better control supply and demand in smart energy grids. According to Azizan, even if we create the most efficient solar panels and batteries, we can never achieve a sustainable grid powered by renewable resources without the right control mechanisms.

    Mechanical engineers like Ahmed, Mueller, Deng, and Azizan serve as the key to realizing the next revolution of computing in design.

    “MechE is in a unique position at the intersection of the computational and physical worlds,” Azizan says. “Mechanical engineers build a bridge between theoretical, algorithmic tools and real, physical world applications.”

    Sophisticated computational tools, coupled with the ground truth mechanical engineers have in the physical world, could unlock limitless possibilities for design engineering, well beyond what could have been imagined in those early days of CAD. More

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    Saving seaweed with machine learning

    Last year, Charlene Xia ’17, SM ’20 found herself at a crossroads. She was finishing up her master’s degree in media arts and sciences from the MIT Media Lab and had just submitted applications to doctoral degree programs. All Xia could do was sit and wait. In the meantime, she narrowed down her career options, regardless of whether she was accepted to any program.

    “I had two thoughts: I’m either going to get a PhD to work on a project that protects our planet, or I’m going to start a restaurant,” recalls Xia.

    Xia poured over her extensive cookbook collection, researching international cuisines as she anxiously awaited word about her graduate school applications. She even looked into the cost of a food truck permit in the Boston area. Just as she started hatching plans to open a plant-based skewer restaurant, Xia received word that she had been accepted into the mechanical engineering graduate program at MIT.

    Shortly after starting her doctoral studies, Xia’s advisor, Professor David Wallace, approached her with an interesting opportunity. MathWorks, a software company known for developing the MATLAB computing platform, had announced a new seed funding program in MIT’s Department of Mechanical Engineering. The program encouraged collaborative research projects focused on the health of the planet.

    “I saw this as a super-fun opportunity to combine my passion for food, my technical expertise in ocean engineering, and my interest in sustainably helping our planet,” says Xia.

    Play video

    From MIT Mechanical Engineering: “Saving Seaweed with Machine Learning”

    Wallace knew Xia would be up to the task of taking an interdisciplinary approach to solve an issue related to the health of the planet. “Charlene is a remarkable student with extraordinary talent and deep thoughtfulness. She is pretty much fearless, embracing challenges in almost any domain with the well-founded belief that, with effort, she will become a master,” says Wallace.

    Alongside Wallace and Associate Professor Stefanie Mueller, Xia proposed a project to predict and prevent the spread of diseases in aquaculture. The team focused on seaweed farms in particular.

    Already popular in East Asian cuisines, seaweed holds tremendous potential as a sustainable food source for the world’s ever-growing population. In addition to its nutritive value, seaweed combats various environmental threats. It helps fight climate change by absorbing excess carbon dioxide in the atmosphere, and can also absorb fertilizer run-off, keeping coasts cleaner.

    As with so much of marine life, seaweed is threatened by the very thing it helps mitigate against: climate change. Climate stressors like warm temperatures or minimal sunlight encourage the growth of harmful bacteria such as ice-ice disease. Within days, entire seaweed farms are decimated by unchecked bacterial growth.

    To solve this problem, Xia turned to the microbiota present in these seaweed farms as a predictive indicator of any threat to the seaweed or livestock. “Our project is to develop a low-cost device that can detect and prevent diseases before they affect seaweed or livestock by monitoring the microbiome of the environment,” says Xia.

    The team pairs old technology with the latest in computing. Using a submersible digital holographic microscope, they take a 2D image. They then use a machine learning system known as a neural network to convert the 2D image into a representation of the microbiome present in the 3D environment.

    “Using a machine learning network, you can take a 2D image and reconstruct it almost in real time to get an idea of what the microbiome looks like in a 3D space,” says Xia.

    The software can be run in a small Raspberry Pi that could be attached to the holographic microscope. To figure out how to communicate these data back to the research team, Xia drew upon her master’s degree research.

    In that work, under the guidance of Professor Allan Adams and Professor Joseph Paradiso in the Media Lab, Xia focused on developing small underwater communication devices that can relay data about the ocean back to researchers. Rather than the usual $4,000, these devices were designed to cost less than $100, helping lower the cost barrier for those interested in uncovering the many mysteries of our oceans. The communication devices can be used to relay data about the ocean environment from the machine learning algorithms.

    By combining these low-cost communication devices along with microscopic images and machine learning, Xia hopes to design a low-cost, real-time monitoring system that can be scaled to cover entire seaweed farms.

    “It’s almost like having the ‘internet of things’ underwater,” adds Xia. “I’m developing this whole underwater camera system alongside the wireless communication I developed that can give me the data while I’m sitting on dry land.”

    Armed with these data about the microbiome, Xia and her team can detect whether or not a disease is about to strike and jeopardize seaweed or livestock before it is too late.

    While Xia still daydreams about opening a restaurant, she hopes the seaweed project will prompt people to rethink how they consider food production in general.

    “We should think about farming and food production in terms of the entire ecosystem,” she says. “My meta-goal for this project would be to get people to think about food production in a more holistic and natural way.” More

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    A robot that finds lost items

    A busy commuter is ready to walk out the door, only to realize they’ve misplaced their keys and must search through piles of stuff to find them. Rapidly sifting through clutter, they wish they could figure out which pile was hiding the keys.

    Researchers at MIT have created a robotic system that can do just that. The system, RFusion, is a robotic arm with a camera and radio frequency (RF) antenna attached to its gripper. It fuses signals from the antenna with visual input from the camera to locate and retrieve an item, even if the item is buried under a pile and completely out of view.

    The RFusion prototype the researchers developed relies on RFID tags, which are cheap, battery-less tags that can be stuck to an item and reflect signals sent by an antenna. Because RF signals can travel through most surfaces (like the mound of dirty laundry that may be obscuring the keys), RFusion is able to locate a tagged item within a pile.

    Using machine learning, the robotic arm automatically zeroes-in on the object’s exact location, moves the items on top of it, grasps the object, and verifies that it picked up the right thing. The camera, antenna, robotic arm, and AI are fully integrated, so RFusion can work in any environment without requiring a special set up.

    While finding lost keys is helpful, RFusion could have many broader applications in the future, like sorting through piles to fulfill orders in a warehouse, identifying and installing components in an auto manufacturing plant, or helping an elderly individual perform daily tasks in the home, though the current prototype isn’t quite fast enough yet for these uses.

    “This idea of being able to find items in a chaotic world is an open problem that we’ve been working on for a few years. Having robots that are able to search for things under a pile is a growing need in industry today. Right now, you can think of this as a Roomba on steroids, but in the near term, this could have a lot of applications in manufacturing and warehouse environments,” said senior author Fadel Adib, associate professor in the Department of Electrical Engineering and Computer Science and director of the Signal Kinetics group in the MIT Media Lab.

    Co-authors include research assistant Tara Boroushaki, the lead author; electrical engineering and computer science graduate student Isaac Perper; research associate Mergen Nachin; and Alberto Rodriguez, the Class of 1957 Associate Professor in the Department of Mechanical Engineering. The research will be presented at the Association for Computing Machinery Conference on Embedded Networked Senor Systems next month.

    Play video

    Sending signals

    RFusion begins searching for an object using its antenna, which bounces signals off the RFID tag (like sunlight being reflected off a mirror) to identify a spherical area in which the tag is located. It combines that sphere with the camera input, which narrows down the object’s location. For instance, the item can’t be located on an area of a table that is empty.

    But once the robot has a general idea of where the item is, it would need to swing its arm widely around the room taking additional measurements to come up with the exact location, which is slow and inefficient.

    The researchers used reinforcement learning to train a neural network that can optimize the robot’s trajectory to the object. In reinforcement learning, the algorithm is trained through trial and error with a reward system.

    “This is also how our brain learns. We get rewarded from our teachers, from our parents, from a computer game, etc. The same thing happens in reinforcement learning. We let the agent make mistakes or do something right and then we punish or reward the network. This is how the network learns something that is really hard for it to model,” Boroushaki explains.

    In the case of RFusion, the optimization algorithm was rewarded when it limited the number of moves it had to make to localize the item and the distance it had to travel to pick it up.

    Once the system identifies the exact right spot, the neural network uses combined RF and visual information to predict how the robotic arm should grasp the object, including the angle of the hand and the width of the gripper, and whether it must remove other items first. It also scans the item’s tag one last time to make sure it picked up the right object.

    Cutting through clutter

    The researchers tested RFusion in several different environments. They buried a keychain in a box full of clutter and hid a remote control under a pile of items on a couch.

    But if they fed all the camera data and RF measurements to the reinforcement learning algorithm, it would have overwhelmed the system. So, drawing on the method a GPS uses to consolidate data from satellites, they summarized the RF measurements and limited the visual data to the area right in front of the robot.

    Their approach worked well — RFusion had a 96 percent success rate when retrieving objects that were fully hidden under a pile.

    “Sometimes, if you only rely on RF measurements, there is going to be an outlier, and if you rely only on vision, there is sometimes going to be a mistake from the camera. But if you combine them, they are going to correct each other. That is what made the system so robust,” Boroushaki says.

    In the future, the researchers hope to increase the speed of the system so it can move smoothly, rather than stopping periodically to take measurements. This would enable RFusion to be deployed in a fast-paced manufacturing or warehouse setting.

    Beyond its potential industrial uses, a system like this could even be incorporated into future smart homes to assist people with any number of household tasks, Boroushaki says.

    “Every year, billions of RFID tags are used to identify objects in today’s complex supply chains, including clothing and lots of other consumer goods. The RFusion approach points the way to autonomous robots that can dig through a pile of mixed items and sort them out using the data stored in the RFID tags, much more efficiently than having to inspect each item individually, especially when the items look similar to a computer vision system,” says Matthew S. Reynolds, CoMotion Presidential Innovation Fellow and associate professor of electrical and computer engineering at the University of Washington, who was not involved in the research. “The RFusion approach is a great step forward for robotics operating in complex supply chains where identifying and ‘picking’ the right item quickly and accurately is the key to getting orders fulfilled on time and keeping demanding customers happy.”

    The research is sponsored by the National Science Foundation, a Sloan Research Fellowship, NTT DATA, Toppan, Toppan Forms, and the Abdul Latif Jameel Water and Food Systems Lab. More

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    Research collaboration puts climate-resilient crops in sight

    Any houseplant owner knows that changes in the amount of water or sunlight a plant receives can put it under immense stress. A dying plant brings certain disappointment to anyone with a green thumb. 

    But for farmers who make their living by successfully growing plants, and whose crops may nourish hundreds or thousands of people, the devastation of failing flora is that much greater. As climate change is poised to cause increasingly unpredictable weather patterns globally, crops may be subject to more extreme environmental conditions like droughts, fluctuating temperatures, floods, and wildfire. 

    Climate scientists and food systems researchers worry about the stress climate change may put on crops, and on global food security. In an ambitious interdisciplinary project funded by the Abdul Latif Jameel Water and Food Systems Lab (J-WAFS), David Des Marais, the Gale Assistant Professor in the Department of Civil and Environmental Engineering at MIT, and Caroline Uhler, an associate professor in the MIT Department of Electrical Engineering and Computer Science and the Institute for Data, Systems, and Society, are investigating how plant genes communicate with one another under stress. Their research results can be used to breed plants more resilient to climate change.

    Crops in trouble

    Governing plants’ responses to environmental stress are gene regulatory networks, or GRNs, which guide the development and behaviors of living things. A GRN may be comprised of thousands of genes and proteins that all communicate with one another. GRNs help a particular cell, tissue, or organism respond to environmental changes by signaling certain genes to turn their expression on or off.

    Even seemingly minor or short-term changes in weather patterns can have large effects on crop yield and food security. An environmental trigger, like a lack of water during a crucial phase of plant development, can turn a gene on or off, and is likely to affect many others in the GRN. For example, without water, a gene enabling photosynthesis may switch off. This can create a domino effect, where the genes that rely on those regulating photosynthesis are silenced, and the cycle continues. As a result, when photosynthesis is halted, the plant may experience other detrimental side effects, like no longer being able to reproduce or defend against pathogens. The chain reaction could even kill a plant before it has the chance to be revived by a big rain.

    Des Marais says he wishes there was a way to stop those genes from completely shutting off in such a situation. To do that, scientists would need to better understand how exactly gene networks respond to different environmental triggers. Bringing light to this molecular process is exactly what he aims to do in this collaborative research effort.

    Solving complex problems across disciplines

    Despite their crucial importance, GRNs are difficult to study because of how complex and interconnected they are. Usually, to understand how a particular gene is affecting others, biologists must silence one gene and see how the others in the network respond. 

    For years, scientists have aspired to an algorithm that could synthesize the massive amount of information contained in GRNs to “identify correct regulatory relationships among genes,” according to a 2019 article in the Encyclopedia of Bioinformatics and Computational Biology. 

    “A GRN can be seen as a large causal network, and understanding the effects that silencing one gene has on all other genes requires understanding the causal relationships among the genes,” says Uhler. “These are exactly the kinds of algorithms my group develops.”

    Des Marais and Uhler’s project aims to unravel these complex communication networks and discover how to breed crops that are more resilient to the increased droughts, flooding, and erratic weather patterns that climate change is already causing globally.

    In addition to climate change, by 2050, the world will demand 70 percent more food to feed a booming population. “Food systems challenges cannot be addressed individually in disciplinary or topic area silos,” says Greg Sixt, J-WAFS’ research manager for climate and food systems. “They must be addressed in a systems context that reflects the interconnected nature of the food system.”

    Des Marais’ background is in biology, and Uhler’s in statistics. “Dave’s project with Caroline was essentially experimental,” says Renee J. Robins, J-WAFS’ executive director. “This kind of exploratory research is exactly what the J-WAFS seed grant program is for.”

    Getting inside gene regulatory networks

    Des Marais and Uhler’s work begins in a windowless basement on MIT’s campus, where 300 genetically identical Brachypodium distachyon plants grow in large, temperature-controlled chambers. The plant, which contains more than 30,000 genes, is a good model for studying important cereal crops like wheat, barley, maize, and millet. For three weeks, all plants receive the same temperature, humidity, light, and water. Then, half are slowly tapered off water, simulating drought-like conditions.

    Six days into the forced drought, the plants are clearly suffering. Des Marais’ PhD student Jie Yun takes tissues from 50 hydrated and 50 dry plants, freezes them in liquid nitrogen to immediately halt metabolic activity, grinds them up into a fine powder, and chemically separates the genetic material. The genes from all 100 samples are then sequenced at a lab across the street.

    The team is left with a spreadsheet listing the 30,000 genes found in each of the 100 plants at the moment they were frozen, and how many copies there were. Uhler’s PhD student Anastasiya Belyaeva inputs the massive spreadsheet into the computer program she developed and runs her novel algorithm. Within a few hours, the group can see which genes were most active in one condition over another, how the genes were communicating, and which were causing changes in others. 

    The methodology captures important subtleties that could allow researchers to eventually alter gene pathways and breed more resilient crops. “When you expose a plant to drought stress, it’s not like there’s some canonical response,” Des Marais says. “There’s lots of things going on. It’s turning this physiologic process up, this one down, this one didn’t exist before, and now suddenly is turned on.” 

    In addition to Des Marais and Uhler’s research, J-WAFS has funded projects in food and water from researchers in 29 departments across all five MIT schools as well as the MIT Schwarzman College of Computing. J-WAFS seed grants typically fund seven to eight new projects every year.

    “The grants are really aimed at catalyzing new ideas, providing the sort of support [for MIT researchers] to be pushing boundaries, and also bringing in faculty who may have some interesting ideas that they haven’t yet applied to water or food concerns,” Robins says. “It’s an avenue for researchers all over the Institute to apply their ideas to water and food.”

    Alison Gold is a student in MIT’s Graduate Program in Science Writing. More