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      Solve at MIT 2023: Collaboration and climate efforts are at the forefront of social impact

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      “The scale, complexity, the global nature of the problems we’re dealing with are so big that no single institution, industry, or country can deal with them alone,” MIT President Sally Kornbluth stated in her first remarks to the Solve community.

      Over 300 social impact leaders from around the world convened on MIT’s campus for Solve at MIT 2023 to celebrate the 2022 Solver class and to discuss some of the world’s greatest challenges and how we can tackle them with innovation, entrepreneurship, and technology.

      These challenges can be complicated and may even feel insurmountable, but Solve at MIT leaves us with the hope, tools, and connections needed to find solutions together.

      Hala Hanna, executive director of MIT Solve, shared what keeps her inspired and at the front line of social impact: “Optimism isn’t about looking away from the issues but looking right at them, believing we can create the solutions and putting in the work. So, anytime I need a dose of optimism, I look to the innovators we work with,” Hanna shared during the opening plenary, Unlocking our Collective Potential.

      Over the course of three days, more than 300 individuals from around the world convened to celebrate the 2022 Solver class, create partnerships that lead to progress, and address solutions to pressing world issues in real-time.

      Every technologist, philanthropist, investor, and innovator present at Solve at MIT left with their own takeaway, but three main themes seemed to underscore the overall discussions.

      Technology and innovation are as neutral as the makers

      Having bias is a natural part of what makes us human. However, being aware of our predispositions is necessary to transform our lived experiences into actionable solutions for others to benefit from. 

      We’ve largely learned that bias can be both unavoidable and applied almost instantly. Sangbae Kim, director of the Biomimetic Robotics Laboratory and professor of mechanical engineering at MIT, proved this through robotics demonstrations where attendees almost unanimously were more impressed with a back-flipping MIT robot compared to one walking in circles. As it turns out, it took one individual three days to program a robot to do a flip and over two weeks for a full team to program one to walk. “We judge through the knowledge and bias we have based on our lived experiences,” Kim pointed out.

      Bias and lived experiences don’t have to be bad things. The solutions we create based on our own lives are what matter. 

      2022 Solver Atif Javed, co-founder and executive director of Tarjimly, began translating for his grandmother as a child and learned about the struggles that come with being a refugee. This led him to develop a humanitarian language-translation application, which connects volunteer translators with immigrants, refugees, nongovernmental organizations (NGOs), and more, on demand. 

      Vanessa Castañeda Gill, 2022 Solver and co-founder and CEO of Social Cipher, transformed her personal experience with ADHD and autism to develop Ava, a video game empowering neuro-divergent youth and facilitating social-emotional learning.

      For Kelsey Wirth, co-founder and chair of Mothers Out Front, the experience of motherhood and the shared concerns for the well-being of children are what unite her with other moms. 

      Whitney Wolf Herd, founder and CEO of Bumble, shared that as a leader in technology and a person who witnessed toxic online spaces, she sees it as her responsibility to spearhead change. 

      During the plenary, “Bringing us Together or Tearing us Apart?” Wolf Herd asked, “What if we could use technology to be a force for positivity?” She shared her vision for equality and respect to be part of the next digital wave. She also called for technology leaders to join her to ensure “guardrails and ground rules” are in place to make sure this goal becomes a reality.

      Social innovation must be intersectional and intergenerational

      During Solve at MIT, industry leaders across sectors, cultures, ages, and expertise banded together to address pressing issues and to form relationships with innovators looking for support in real time.

      Adam Bly, founder and CEO of System Inc., discussed the interconnected nature of all things and why his organization is on a mission to show the links, “We’re seeing rising complexity in the systems that make up life on earth, and it impacts us individually and globally. The way we organize the information and data we need to make decisions about those systems [is highly] siloed and highly fragmented, and it impairs our ability to make decisions in the most systemic, holistic, rational way.”

      President and CEO of the National Resources Defense Council Manish Bapna shared his advocacy for cross-sector work: “Part of what I’ve seen really proliferate and expand in a good way over the past 10 to 15 years are collaborations involving startups in the private sector, governments, and NGOs. No single stakeholder or organization can solve the problem, but by coming together, they bring different perspectives and skills in ways that can create the innovation we need to see.”

      For a long time, STEM (science, technology, engineering, and math) were seen as the subjects that would resolve our complex issues, but as it turns out, art also holds a tremendous amount of power to transcend identity, borders, status, and concerns, to connect us all and aid us in global unity. Artists Beatie Wolfe, Norhan Bayomi, Aida Murad, and Nneka Jones showed us how to bring healing and awareness to topics like social and environmental injustice through their music, embroidery, and painting.

      The 2023 Solv[ED] Innovators, all age 24 or under, have solutions that are improving communication for individuals with hearing loss, transforming plastic waste into sustainable furniture, and protecting the Black birthing community, among other incredible feats.

      Kami Dar, co-founder and CEO of Uniti Networks, summarizes the value of interconnected problem-solving: “My favorite SDG [sustainable development goal] is SDG number 17— the power of partnership. Look for the adjacent problem-solvers and make sure we are not reinventing the wheel.”

      Relationships and the environment connect us all

      Solve is working to address global challenges on an ongoing basis connected to climate, economic prosperity, health, and learning. Many of these focus areas bleed into one another, but social justice and climate action served as a backdrop for many global issues addressed during Solve at MIT.

      “When we started addressing climate change, we saw it primarily as technical issues to bring down emissions … There’s inequality, there’s poverty, there are social tensions that are rising … We are not going to address climate change without addressing the social tensions that are embedded,” said Lewis Akenji, managing director of the Hot or Cool Institute. Akenji sees food, mobility, and housing as the most impactful areas to focus solutions on first.

      During the “Ensuring a Just Transition to Net Zero” plenary, Heather Clancy, vice president and editorial director at Greenbiz, asked panelists what lessons they have learned from their work. Janelle Knox Hayes, ​​professor of economic geography and planning at MIT, shared that listening to communities, especially front-line and Indigenous communities, is needed before deploying solutions to the energy crisis. “Climate work has this sense of urgency, like it rapidly has to be done … to do really engaged environmental justice work, we have to slow down and realize even before we begin, we need a long period of time to plan. But before we even do that, we have to rebuild relationships and trust and reciprocity … [This] will lead to better and longer-lasting solutions.”

      Hina Baloch, executive director and global head of climate change and sustainability strategy and communication at General Motors, asked Chéri Smith, founder of Indigenous Energy Initiative, to share her perspective on energy sovereignty as it relates to Indigenous communities. Smith shared, “Tribes can’t be sovereign if they’re relying on outside sources for their energy. We were founded to support the self-determination of tribes to revamp their energy systems and rebuild, construct, and maintain them themselves.”

      Smith shared an example of human and tribal-centered innovation in the making. Through the Biden administration’s national electronic vehicle (EV) initiative, Indigenous Energy Initiative and Native Sun Community Power Development will collaborate and create an inter-tribal EV charging network. “The last time we built out an electric grid, it deliberately skipped over tribal country. This time, we want to make sure that we not only have a seat at the table, but that we build out the tables and invite everyone to them,” said Smith.

      Solve at MIT led to meaningful discussions about climate change, intersectional and accessible innovation, and the power that human connection has to unite everyone. Entrepreneurship and social change are the paths forward. And although the challenges ahead of us can be daunting, with community, collaboration, and a healthy dose of bravery, global challenges will continue to be solved by agile impact entrepreneurs all around the world. 

      As Adrianne Haslet, a professional ballroom dancer and Boston Marathon bombing survivor, reminded attendees, “What will get you to the finish line is nothing compared to what got you to the start line.” More

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      Finding “hot spots” where compounding environmental and economic risks converge

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      A computational tool developed by researchers at the MIT Joint Program on the Science and Policy of Global Change pinpoints specific counties within the United States that are particularly vulnerable to economic distress resulting from a transition from fossil fuels to low-carbon energy sources. By combining county-level data on employment in fossil fuel (oil, natural gas, and coal) industries with data on populations below the poverty level, the tool identifies locations with high risks for transition-driven economic hardship. It turns out that many of these high-risk counties are in the south-central U.S., with a heavy concentration in the lower portions of the Mississippi River.

      The computational tool, which the researchers call the System for the Triage of Risks from Environmental and Socio-economic Stressors (STRESS) platform, almost instantly displays these risk combinations on an easy-to-read visual map, revealing those counties that stand to gain the most from targeted green jobs retraining programs.  

      Drawing on data that characterize land, water, and energy systems; biodiversity; demographics; environmental equity; and transportation networks, the STRESS platform enables users to assess multiple, co-evolving, compounding hazards within a U.S. geographical region from the national to the county level. Because of its comprehensiveness and precision, this screening-level visualization tool can pinpoint risk “hot spots” that can be subsequently investigated in greater detail. Decision-makers can then plan targeted interventions to boost resilience to location-specific physical and economic risks.

      The platform and its applications are highlighted in a new study in the journal Frontiers in Climate.

      “As risks to natural and managed resources — and to the economies that depend upon them — become more complex, interdependent, and compounding amid rapid environmental and societal changes, they require more and more human and computational resources to understand and act upon,” says MIT Joint Program Deputy Director C. Adam Schlosser, the lead author of the study. “The STRESS platform provides decision-makers with an efficient way to combine and analyze data on those risks that matter most to them, identify ‘hot spots’ of compounding risk, and design interventions to minimize that risk.”

      In one demonstration of the STRESS platform’s capabilities, the study shows that national and global actions to reduce greenhouse gas emissions could simultaneously reduce risks to land, water, and air quality in the upper Mississippi River basin while increasing economic risks in the lower basin, where poverty and unemployment are already disproportionate. In another demonstration, the platform finds concerning “hot spots” where flood risk, poverty, and nonwhite populations coincide.

      The risk triage platform is based on an emerging discipline called multi-sector dynamics (MSD), which seeks to understand and model compounding risks and potential tipping points across interconnected natural and human systems. Tipping points occur when these systems can no longer sustain multiple, co-evolving stresses, such as extreme events, population growth, land degradation, drinkable water shortages, air pollution, aging infrastructure, and increased human demands. MSD researchers use observations and computer models to identify key precursory indicators of such tipping points, providing decision-makers with critical information that can be applied to mitigate risks and boost resilience in natural and managed resources. With funding from the U.S. Department of Energy, the MIT Joint Program has since 2018 been developing MSD expertise and modeling tools and using them to explore compounding risks and potential tipping points in selected regions of the United States.

      Current STRESS platform data includes more than 100 risk metrics at the county-level scale, but data collection is ongoing. MIT Joint Program researchers are continuing to develop the STRESS platform as an “open-science tool” that welcomes input from academics, researchers, industry and the general public. More

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      in Environment

      Four researchers with MIT ties earn 2023 Schmidt Science Fellowships

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      Four researchers with ties to MIT have been named Schmidt Science Fellows this year. Lillian Chin ’17, SM ’19; Neil Dalvie PD ’22, PhD ’22; Suong Nguyen, and Yirui Zhang SM ’19, PhD ’23 are among the 32 exceptional early-career scientists worldwide chosen to receive the prestigious fellowships.

      “History provides powerful examples of what happens when scientists are given the freedom to ask big questions which can achieve real breakthroughs across disciplines,” says Wendy Schmidt, co-founder of Schmidt Futures and president of the Schmidt Family Foundation. “Schmidt Science Fellows are tackling climate destruction, discovering new drugs against disease, developing novel materials, using machine learning to understand the drivers of human health, and much more. This new cohort will add to this legacy in applying scientific discovery to improve human health and opportunity, and preserve and restore essential planetary systems.”

      Schmidt Futures is a philanthropic initiative that brings talented people together in networks to prove out their ideas and solve hard problems in science and society. Schmidt Science Fellows receive a stipend of $100,000 a year for up to two years of postdoctoral research in a discipline different from their PhD at a world-leading lab anywhere across the globe.

      Lillian Chin ’17, SM ’19 is currently pursuing her PhD in the Department of Electrical Engineering and Computer Science. Her research focuses on creating new materials for robots. By designing the geometry of a material, Chin creates new “meta-materials” that have different properties from the original. Using this technique, she has created robot balls that dramatically expand in volume and soft grippers that can work in dangerous environments. All of these robots are built out of a single material, letting the researchers 3D print them with extra internal features like channels. These channels help to measure the deformation of metamaterials, enabling Chin and her collaborators to create robots that are strong, can move, and sense their own shape, like muscles do.

      “I feel very honored to have been chosen for this fellowship,” says Chin. “I feel like I proposed a very risky pivot, since my background is only in engineering, with very limited exposure to neuroscience. I’m very excited to be given the opportunity to learn best practices for interacting with patients and be able to translate my knowledge from robotics to biology.”

      With the Schmidt Fellowship, Chin plans to pursue new frontiers for custom materials with internal sensors, which can measure force and deformation and can be placed anywhere within the material. “I want to use these materials to make tools for clinicians and neuroscientists to better understand how humans touch and grasp objects around them,” says Chin. “I’m especially interested in seeing how my materials could help in diagnosis motor-related diseases or improve rehab outcomes by providing the patient with feedback. This will help me create robots that have a better sense of touch and learn how to move objects around like humans do.”

      Neil Dalvie PD ’22, PhD ’22 is a graduate of the Department of Chemical Engineering, where he worked with Professor J. Christopher Love on manufacturing of therapeutic proteins. Dalvie developed molecular biology techniques for manufacturing high-quality proteins in yeast, which enables rapid testing of new products and low-cost manufacturing and large scales. During the pandemic, he led a team that applied these learnings to develop a Covid-19 vaccine that was deployed in multiple low-income countries. After graduating, Dalvie wanted to apply the precision biological engineering that is routinely deployed in medicinal manufacturing to other large-scale bioprocesses.

      “It’s rare for scientists to cross large technical gaps after so many years of specific training to get a PhD — you get comfy being an expert in your field,” says Dalvie. “I was definitely intimidated by the giant leap from vaccine manufacturing to the natural rock cycle. The fellowship has allowed me to dive into the new field by removing immediate pressure to publish or find my next job. I am excited for what commonalities we will find between biomanufacturing and biogeochemistry.”

      As a Schmidt Science Fellow, Dalvie will work with Professor Pamela Silver at Harvard Medical School on engineering microorganisms for enhanced rock weathering and carbon sequestration to combat climate change. They are applying modern molecular biology to enhance natural biogeochemical processes at gigaton scales.

      Suong (Su) Nguyen, a postdoctoral researcher in Professor Jeremiah Johnson’s lab in the Department of Chemistry, earned her PhD from Princeton University, where she developed light-driven, catalytic methodologies for organic synthesis, biomass valorization, plastic waste recycling, and functionalization of quantum sensing materials.

      As a Schmidt Science fellow, Nguyen will pivot from organic chemistry to nanomaterials. Biological systems are able to synthesize macromolecules with precise structure essential for their biological function. Scientists have long dreamed of achieving similar control over synthetic materials, but existing methods are inefficient and limited in scope. Nguyen hopes to develop new strategies to achieve such high level of control over the structure and properties of nanomaterials and explore their potential for use in therapeutic applications.

      “I feel extremely honored and grateful to receive the Schmidt Science Fellowship,” says Nguyen. “The fellowship will provide me with a unique opportunity to engage with scientists from a very wide range of research backgrounds. I believe this will significantly shape the research objectives for my future career.”

      Yirui Zhang SM ’19, PhD ’22 is a graduate of the Department of Mechanical Engineering. Zhang’s research focuses on electrochemical energy storage and conversion, including lithium-ion batteries and electrocatalysis. She has developed in situ spectroscopy and electrochemical methods to probe the electrode-electrolyte interface, understand the interfacial molecular structures, and unravel the fundamental thermodynamics and kinetics of (electro)chemical reactions in energy storage. Further, she has leveraged the physical chemistry of liquids and tuned the molecular structures at the interface to improve the stability and kinetics of electrochemical reactions. 

      “I am honored and thrilled to have been named a Schmidt Science Fellow,” says Zhang. “The fellowship will not only provide me with the unique opportunity to broaden my scientific perspectives and pursue pivoting research, but also create a lifelong network for us to collaborate across diverse fields and become scientific and societal thought leaders. I look forward to pushing the boundaries of my research and advancing technologies to tackle global challenges in energy storage and health care with interdisciplinary efforts!”

      As a Schmidt Science Fellow, Zhang will work across disciplines and pivot to biosensing. She plans to combine spectroscopy, electrokinetics, and machine learning to develop a fast and cost-effective technique for monitoring and understanding infectious disease. The innovations will benefit next-generation point-of-care medical devices and wastewater-based epidemiology to provide timely diagnosis and help protect humans against deadly infections and antimicrobial resistance. More

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      in Environment

      Inaugural J-WAFS Grand Challenge aims to develop enhanced crop variants and move them from lab to land

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      According to MIT’s charter, established in 1861, part of the Institute’s mission is to advance the “development and practical application of science in connection with arts, agriculture, manufactures, and commerce.” Today, the Abdul Latif Jameel Water and Food Systems Lab (J-WAFS) is one of the driving forces behind water and food-related research on campus, much of which relates to agriculture. In 2022, J-WAFS established the Water and Food Grand Challenge Grant to inspire MIT researchers to work toward a water-secure and food-secure future for our changing planet. Not unlike MIT’s Climate Grand Challenges, the J-WAFS Grand Challenge seeks to leverage multiple areas of expertise, programs, and Institute resources. The initial call for statements of interests returned 23 letters from MIT researchers spanning 18 departments, labs, and centers. J-WAFS hosted workshops for the proposers to present and discuss their initial ideas. These were winnowed down to a smaller set of invited concept papers, followed by the final proposal stage. 

      Today, J-WAFS is delighted to report that the inaugural J-WAFS Grand Challenge Grant has been awarded to a team of researchers led by Professor Matt Shoulders and research scientist Robert Wilson of the Department of Chemistry. A panel of expert, external reviewers highly endorsed their proposal, which tackles a longstanding problem in crop biology — how to make photosynthesis more efficient. The team will receive $1.5 million over three years to facilitate a multistage research project that combines cutting-edge innovations in synthetic and computational biology. If successful, this project could create major benefits for agriculture and food systems worldwide.

      “Food systems are a major source of global greenhouse gas emissions, and they are also increasingly vulnerable to the impacts of climate change. That’s why when we talk about climate change, we have to talk about food systems, and vice versa,” says Maria T. Zuber, MIT’s vice president for research. “J-WAFS is central to MIT’s efforts to address the interlocking challenges of climate, water, and food. This new grant program aims to catalyze innovative projects that will have real and meaningful impacts on water and food. I congratulate Professor Shoulders and the rest of the research team on being the inaugural recipients of this grant.”

      Shoulders will work with Bryan Bryson, associate professor of biological engineering, as well as Bin Zhang, associate professor of chemistry, and Mary Gehring, a professor in the Department of Biology and the Whitehead Institute for Biomedical Research. Robert Wilson from the Shoulders lab will be coordinating the research effort. The team at MIT will work with outside collaborators Spencer Whitney, a professor from the Australian National University, and Ahmed Badran, an assistant professor at the Scripps Research Institute. A milestone-based collaboration will also take place with Stephen Long, a professor from the University of Illinois at Urbana-Champaign. The group consists of experts in continuous directed evolution, machine learning, molecular dynamics simulations, translational plant biochemistry, and field trials.

      “This project seeks to fundamentally improve the RuBisCO enzyme that plants use to convert carbon dioxide into the energy-rich molecules that constitute our food,” says J-WAFS Director John H. Lienhard V. “This difficult problem is a true grand challenge, calling for extensive resources. With J-WAFS’ support, this long-sought goal may finally be achieved through MIT’s leading-edge research,” he adds.

      RuBisCO: No, it’s not a new breakfast cereal; it just might be the key to an agricultural revolution

      A growing global population, the effects of climate change, and social and political conflicts like the war in Ukraine are all threatening food supplies, particularly grain crops. Current projections estimate that crop production must increase by at least 50 percent over the next 30 years to meet food demands. One key barrier to increased crop yields is a photosynthetic enzyme called Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase (RuBisCO). During photosynthesis, crops use energy gathered from light to draw carbon dioxide (CO2) from the atmosphere and transform it into sugars and cellulose for growth, a process known as carbon fixation. RuBisCO is essential for capturing the CO2 from the air to initiate conversion of CO2 into energy-rich molecules like glucose. This reaction occurs during the second stage of photosynthesis, also known as the Calvin cycle. Without RuBisCO, the chemical reactions that account for virtually all carbon acquisition in life could not occur.

      Unfortunately, RuBisCO has biochemical shortcomings. Notably, the enzyme acts slowly. Many other enzymes can process a thousand molecules per second, but RuBisCO in chloroplasts fixes less than six carbon dioxide molecules per second, often limiting the rate of plant photosynthesis. Another problem is that oxygen (O2) molecules and carbon dioxide molecules are relatively similar in shape and chemical properties, and RuBisCO is unable to fully discriminate between the two. The inadvertent fixation of oxygen by RuBisCO leads to energy and carbon loss. What’s more, at higher temperatures RuBisCO reacts even more frequently with oxygen, which will contribute to decreased photosynthetic efficiency in many staple crops as our climate warms.

      The scientific consensus is that genetic engineering and synthetic biology approaches could revolutionize photosynthesis and offer protection against crop losses. To date, crop RuBisCO engineering has been impaired by technological obstacles that have limited any success in significantly enhancing crop production. Excitingly, genetic engineering and synthetic biology tools are now at a point where they can be applied and tested with the aim of creating crops with new or improved biological pathways for producing more food for the growing population.

      An epic plan for fighting food insecurity

      The 2023 J-WAFS Grand Challenge project will use state-of-the-art, transformative protein engineering techniques drawn from biomedicine to improve the biochemistry of photosynthesis, specifically focusing on RuBisCO. Shoulders and his team are planning to build what they call the Enhanced Photosynthesis in Crops (EPiC) platform. The project will evolve and design better crop RuBisCO in the laboratory, followed by validation of the improved enzymes in plants, ultimately resulting in the deployment of enhanced RuBisCO in field trials to evaluate the impact on crop yield. 

      Several recent developments make high-throughput engineering of crop RuBisCO possible. RuBisCO requires a complex chaperone network for proper assembly and function in plants. Chaperones are like helpers that guide proteins during their maturation process, shielding them from aggregation while coordinating their correct assembly. Wilson and his collaborators previously unlocked the ability to recombinantly produce plant RuBisCO outside of plant chloroplasts by reconstructing this chaperone network in Escherichia coli (E. coli). Whitney has now established that the RuBisCO enzymes from a range of agriculturally relevant crops, including potato, carrot, strawberry, and tobacco, can also be expressed using this technology. Whitney and Wilson have further developed a range of RuBisCO-dependent E. coli screens that can identify improved RuBisCO from complex gene libraries. Moreover, Shoulders and his lab have developed sophisticated in vivo mutagenesis technologies that enable efficient continuous directed evolution campaigns. Continuous directed evolution refers to a protein engineering process that can accelerate the steps of natural evolution simultaneously in an uninterrupted cycle in the lab, allowing for rapid testing of protein sequences. While Shoulders and Badran both have prior experience with cutting-edge directed evolution platforms, this will be the first time directed evolution is applied to RuBisCO from plants.

      Artificial intelligence is changing the way enzyme engineering is undertaken by researchers. Principal investigators Zhang and Bryson will leverage modern computational methods to simulate the dynamics of RuBisCO structure and explore its evolutionary landscape. Specifically, Zhang will use molecular dynamics simulations to simulate and monitor the conformational dynamics of the atoms in a protein and its programmed environment over time. This approach will help the team evaluate the effect of mutations and new chemical functionalities on the properties of RuBisCO. Bryson will employ artificial intelligence and machine learning to search the RuBisCO activity landscape for optimal sequences. The computational and biological arms of the EPiC platform will work together to both validate and inform each other’s approaches to accelerate the overall engineering effort.

      Shoulders and the group will deploy their designed enzymes in tobacco plants to evaluate their effects on growth and yield relative to natural RuBisCO. Gehring, a plant biologist, will assist with screening improved RuBisCO variants using the tobacco variety Nicotiana benthamianaI, where transient expression can be deployed. Transient expression is a speedy approach to test whether novel engineered RuBisCO variants can be correctly synthesized in leaf chloroplasts. Variants that pass this quality-control checkpoint at MIT will be passed to the Whitney Lab at the Australian National University for stable transformation into Nicotiana tabacum (tobacco), enabling robust measurements of photosynthetic improvement. In a final step, Professor Long at the University of Illinois at Urbana-Champaign will perform field trials of the most promising variants.

      Even small improvements could have a big impact

      A common criticism of efforts to improve RuBisCO is that natural evolution has not already identified a better enzyme, possibly implying that none will be found. Traditional views have speculated a catalytic trade-off between RuBisCO’s specificity factor for CO2 / O2 versus its CO2 fixation efficiency, leading to the belief that specificity factor improvements might be offset by even slower carbon fixation or vice versa. This trade-off has been suggested to explain why natural evolution has been slow to achieve a better RuBisCO. But Shoulders and the team are convinced that the EPiC platform can unlock significant overall improvements to plant RuBisCO. This view is supported by the fact that Wilson and Whitney have previously used directed evolution to improve CO2 fixation efficiency by 50 percent in RuBisCO from cyanobacteria (the ancient progenitors of plant chloroplasts) while simultaneously increasing the specificity factor. 

      The EPiC researchers anticipate that their initial variants could yield 20 percent increases in RuBisCO’s specificity factor without impairing other aspects of catalysis. More sophisticated variants could lift RuBisCO out of its evolutionary trap and display attributes not currently observed in nature. “If we achieve anywhere close to such an improvement and it translates to crops, the results could help transform agriculture,” Shoulders says. “If our accomplishments are more modest, it will still recruit massive new investments to this essential field.”

      Successful engineering of RuBisCO would be a scientific feat of its own and ignite renewed enthusiasm for improving plant CO2 fixation. Combined with other advances in photosynthetic engineering, such as improved light usage, a new green revolution in agriculture could be achieved. Long-term impacts of the technology’s success will be measured in improvements to crop yield and grain availability, as well as resilience against yield losses under higher field temperatures. Moreover, improved land productivity together with policy initiatives would assist in reducing the environmental footprint of agriculture. With more “crop per drop,” reductions in water consumption from agriculture would be a major boost to sustainable farming practices.

      “Our collaborative team of biochemists and synthetic biologists, computational biologists, and chemists is deeply integrated with plant biologists and field trial experts, yielding a robust feedback loop for enzyme engineering,” Shoulders adds. “Together, this team will be able to make a concerted effort using the most modern, state-of-the-art techniques to engineer crop RuBisCO with an eye to helping make meaningful gains in securing a stable crop supply, hopefully with accompanying improvements in both food and water security.” More

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      in Energy

      The answer may be blowing in the wind

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      Capturing energy from the winds gusting off the coasts of the United States could more than double the nation’s electricity generation. It’s no wonder the Biden administration views this immense, clean-energy resource as central to its ambitious climate goals of 100 percent carbon-emissions-free electricity by 2035 and a net-zero emissions economy by 2050. The White House is aiming for 30 gigawatts of offshore wind by 2030 — enough to power 10 million homes.

      At the MIT Energy Initiative’s Spring Symposium, academic experts, energy analysts, wind developers, government officials, and utility representatives explored the immense opportunities and formidable challenges of tapping this titanic resource, both in the United States and elsewhere in the world.

      “There’s a lot of work to do to figure out how to use this resource economically — and sooner rather than later,” said Robert C. Armstrong, MITEI director and the Chevron Professor of Chemical Engineering, in his introduction to the event. 

      In sessions devoted to technology, deployment and integration, policy, and regulation, participants framed the issues critical to the development of offshore wind, described threats to its rapid rollout, and offered potential paths for breaking through gridlock.

      R&D advances

      Moderating a panel on MIT research that is moving the industry forward, Robert Stoner, MITEI’s deputy director for science and technology, provided context for the audience about the industry.

      “We have a high degree of geographic coincidence between where that wind capacity is and where most of us are, and it’s complementary to solar,” he said. Turbines sited in deeper, offshore waters gain the advantage of higher-velocity winds. “You can make these machines huge, creating substantial economies of scale,” said Stoner. An onshore turbine generates approximately 3 megawatts; offshore structures can each produce 15 to 17 megawatts, with blades the length of a football field and heights greater than the Washington Monument.

      To harness the power of wind farms spread over hundreds of nautical miles in deep water, Stoner said, researchers must first address some serious issues, including building and maintaining these massive rigs in harsh environments, laying out wind farms to optimize generation, and creating reliable and socially acceptable connections to the onshore grid. MIT scientists described how they are tackling a number of these problems.

      “When you design a floating structure, you have to prepare for the worst possible conditions,” said Paul Sclavounos, a professor of mechanical engineering and naval architecture who is developing turbines that can withstand severe storms that batter turbine blades and towers with thousands of tons of wind force. Sclavounos described systems used in the oil industry for tethering giant, buoyant rigs to the ocean floor that could be adapted for wind platforms. Relatively inexpensive components such as polyester mooring lines and composite materials “can mitigate the impact of high waves and big, big wind loads.”

      To extract the maximum power from individual turbines, developers must take into account the aerodynamics among turbines in a single wind farm and between adjacent wind farms, according to Michael Howland, the Esther and Harold E. Edgerton Assistant Professor of Civil and Environmental Engineering. Howland’s work modeling turbulence in the atmosphere and wind speeds has demonstrated that angling turbines by just a small amount relative to each other can increase power production significantly for offshore installations, dramatically improving their efficiencies. Howland hopes his research will promote “changing the design of wind farms from the beginning of the process.”

      There’s a staggering complexity to integrating electricity from offshore wind into regional grids such as the one operated by ISO New England, whether converting voltages or monitoring utility load. Steven B. Leeb, a professor of electrical engineering and computer science and of mechanical engineering, is developing sensors that can indicate electronic failures in a micro grid connected to a wind farm. And Marija Ilić, a joint adjunct professor in the Department of Electrical Engineering and Computer Science and a senior research scientist at the Laboratory for Information and Decision Systems, is developing software that would enable real-time scheduling of controllable equipment to compensate for the variable power generated by wind and other variable renewable resources. She is also working on adaptive distributed automation of this equipment to ensure a stable electric power grid.

      “How do we get from here to there?”

      Symposium speakers provided snapshots of the emerging offshore industry, sharing their sense of urgency as well as some frustrations.

      Climate poses “an existential crisis” that calls for “a massive war-footing undertaking,” said Melissa Hoffer, who occupies the newly created cabinet position of climate chief for the Commonwealth of Massachusetts. She views wind power “as the backbone of electric sector decarbonization.” With the Vineyard Wind project, the state will be one of the first in the nation to add offshore wind to the grid. “We are actually going to see the first 400 megawatts … likely interconnected and coming online by the end of this year, which is a fantastic milestone for us,” said Hoffer.

      The journey to completing Vineyard Wind involved a plethora of painstaking environmental reviews, lawsuits over lease siting, negotiations over the price of the electricity it will produce, buy-in from towns where its underground cable comes ashore, and travels to an Eversource substation. It’s a familiar story to Alla Weinstein, founder and CEO of Trident Winds, Inc. On the West Coast, where deep waters (greater than 60 meters) begin closer to shore, Weinstein is trying to launch floating offshore wind projects. “I’ve been in marine renewables for 20 years, and when people ask why I do what I do, I tell them it’s because it matters,” she said. “Because if we don’t do it, we may not have a planet that’s suitable for humans.”

      Weinstein’s “picture of reality” describes a multiyear process during which Trident Winds must address the concerns of such stakeholders as tribal communities and the fishing industry and ensure compliance with, among other regulations, the Marine Mammal Protection Act and the Migratory Bird Species Act. Construction of these massive floating platforms, when it finally happens, will require as-yet unbuilt specialized port infrastructure and boats, and a large skilled labor force for assembly and transmission. “This is a once-in-a-lifetime opportunity to create a new industry,” she said, but “how do we get from here to there?”

      Danielle Jensen, technical manager for Shell’s Offshore Wind Americas, is working on a project off of Rhode Island. The blueprint calls for high-voltage, direct-current cable snaking to landfall in Massachusetts, where direct-current lines switch to alternating current to connect to the grid. “None of this exists, so we have to find a space, the lands, and the right types of cables, tie into the interconnection point, and work with interconnection operators to do that safely and reliably,” she said.

      Utilities are partnering with developers to begin clearing some of these obstacles. Julia Bovey, director of offshore wind for Eversource, described her firm’s redevelopment or improvement of five ports, and new transport vessels for offshore assembly of wind farm components in Atlantic waters. The utility is also digging under roads to lay cables for new power lines. Bovey notes that snags in supply chains and inflation have been driving up costs. This makes determining future electricity rates more complex, especially since utility contracts and markets work differently in each state.

      Just seven up

      Other nations hold a commanding lead in offshore wind: To date, the United States claims just seven operating turbines, while Denmark boasts 6,200 and the U.K. 2,600. Europe’s combined offshore power capacity stands at 30 gigawatts — which, as MITEI Research Scientist Tim Schittekatte notes, is the U.S. goal for 2030.

      The European Union wants 400 gigawatts of offshore wind by 2050, a target made all the more urgent by threats to Europe’s energy security from the war in Ukraine. “The idea is to connect all those windmills, creating a mesh offshore grid,” Schittekatte said, aided by E.U. regulations that establish “a harmonized process to build cross-border infrastructure.”

      Morten Pindstrup, the international chief engineer at Energinet, Denmark’s state-owned energy enterprise, described one component of this pan-European plan: a hybrid Danish-German offshore wind network. Energinet is also constructing energy islands in the North Sea and the Baltic to pool power from offshore wind farms and feed power to different countries.

      The European wind industry benefits from centralized planning, regulation, and markets, said Johannes P. Pfeifenberger, a principal of The Brattle Group. “The grid planning process in the U.S. is not suitable today to find cost-effective solutions to get us to a clean energy grid in time,” he said. Pfeifenberger recommended that the United States immediately pursue a series of moves including a multistate agreement for cooperating on offshore wind and establishment by grid operators of compatible transmission technologies.

      Symposium speakers expressed sharp concerns that complicated and prolonged approvals, as well as partisan politics, could hobble the nation’s nascent offshore industry. “You can develop whatever you want and agree on what you’re doing, and then the people in charge change, and everything falls apart,” said Weinstein. “We can’t slow down, and we actually need to accelerate.”

      Larry Susskind, the Ford Professor of Urban and Environmental Planning, had ideas for breaking through permitting and political gridlock. A negotiations expert, he suggested convening confidential meetings for stakeholders with competing interests for collaborative problem-solving sessions. He announced the creation of a Renewable Energy Facility Siting Clinic at MIT. “We get people to agree that there is a problem, and to accept that without a solution, the system won’t work in the future, and we have to start fixing it now.”

      Other symposium participants were more sanguine about the success of offshore wind. “Trust me, floating wind is not a pie-in-the-sky, exotic technology that is difficult to implement,” said Sclavounos. “There will be companies investing in this technology because it produces huge amounts of energy, and even though the process may not be streamlined, the economics will work itself out.” More

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      US and UAE governments highlight early warning system for climate resilience

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      The following is a joint announcement from MIT and Community Jameel.

      An international project to build community resilience to the effects of climate change, launched by Community Jameel and a research team at MIT, has been recognized as an innovation sprint at the 2023 summit of the United States’ and United Arab Emirates’ Agriculture Innovation Mission for Climate (AIM4C).

      The Jameel Observatory Climate Resilience Early Warning System Network (Jameel Observatory-CREWSnet), one of MIT’s five Climate Grand Challenges flagship projects, aims to empower communities worldwide, specifically within the agriculture sector, to adapt to climate shocks by launching cross-sector collaborations and by combining state-of-the-art climate and socioeconomic forecasting techniques with technological solutions to support communities’ resilience.

      AIM4C is a joint initiative of the U.S. and U.A.E. that seeks to enhance climate action by accelerating agriculture and food systems innovation and investment. Innovation sprints are selected by AIM4C to accelerate their impact following a competitive process that considers scientific excellence and financial support.

      “As we launch Jameel Observatory-CREWSnet, the AIM4C summit offers a great opportunity to share our plans and initial work with all those who are interested in enhancing the capacity of agricultural communities in vulnerable countries to deal with challenges of climate change,” says Elfatih Eltahir, HM King Bhumibol Professor of Hydrology and Climate at MIT and project leader of the Jameel Observatory-CREWSnet.

      Jameel Observatory-CREWSnet seeks to bridge the gap between the knowledge about climate change created at research institutions such as MIT and the local farming communities that are adapting to the impacts of climate change. By effectively informing and engaging local communities, the project seeks to enable farmers to sustainably increase their agricultural productivity and income.     

      The Jameel Observatory-CREWSnet will initially pilot in Bangladesh and Sudan, working with local partners BRAC, a leading international nonprofit headquartered in Bangladesh, and the Agricultural Research Corporation-Sudan, the principal agricultural research arm of the Sudanese government, and with MIT’s Abdul Latif Jameel Poverty Action Lab (J-PAL), the global research center working to reduce poverty by ensuring that policy is informed by scientific evidence. Beginning in southwestern Bangladesh, the Jameel Observatory-CREWSnet will integrate next-generation climate forecasting, predictive analytics, new technologies, and financial instruments. In East Africa, with a focus on Sudan, the initiative will emphasize adopting modern technology to use a better variety of heat-resistant seeds, increasing the use of targeted fertilizers, strengthening soils through soil fertility mapping combined with data modeling, and emphasizing vertical expansion of agriculture over traditional horizontal expansion. The work in Sudan is extensible to other regions in Africa. Jameel Observatory-CREWSnet’s activities and timeline will be reevaluated as the team monitors the ongoing situation in Sudan.

      Using local climate insights, communities will be empowered to adapt proactively to climate change by optimally planning their agricultural activities, targeting emergent economic opportunities, and proactively managing risks from climate change.

      George Richards, director of Community Jameel, says: “Community Jameel is proud to be collaborating with MIT, BRAC, and the Agricultural Research Corporation-Sudan to empower agricultural communities to adapt to the ever-growing challenges arising from climate change — challenges which, as we are seeing acutely in Sudan, are compounded by other crises. We welcome the support of the U.S. and U.A.E. governments in selecting the Jameel Observatory-CREWSnet as an AIM4C innovation sprint.”

      Md Liakath Ali, director of climate change, urban development, and disaster risk management at BRAC, says: “Over our five decades working alongside climate-vulnerable communities in Bangladesh, BRAC has seen firsthand how locally led climate adaptation helps protect lives and livelihoods. BRAC is proud to work with Community Jameel and MIT to empower vulnerable communities to proactively adapt to the impacts of climate change.”

      The Jameel Observatory-CREWSnet was launched at COP27 in Sharm El Sheikh as part of the Jameel Observatory, an international collaboration launched in 2021 that focuses on convening researchers and practitioners who use data and technology to help communities adapt to the impacts of climate change and short-term climate shocks.

      The Jameel Observatory focuses on using data and evidence to prepare for and act on environmental shocks as well as those impacts of climate change and variability which threaten human and environmental well-being. With a special focus on low- and middle-income countries, the Jameel Observatory works at the interface of climate, natural disasters, agricultural and food systems, and health. It emphasizes the need to incorporate local as well as scientific knowledge to prepare and act in anticipation of environmental shocks.

      Launched in 2020, MIT’s Climate Grand Challenges initiative is designed to mobilize the Institute’s research community around tackling the most difficult unsolved climate problems in emissions reduction, climate adaptation and resilience, risk forecasting, carbon removal, and understanding the human impacts of climate change. MIT selected 27 teams as finalists from a field of nearly 100 initial proposals. In 2022, five teams with the most promising concepts were announced as multi-year flagship projects. More

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      in Environment

      Governing for our descendants

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      Social scientists worry that too often we think only of ourselves. 

      “There’s been an increasing recognition that over the last few decades the economy and society have become incredibly focused on the individual, to the detriment of our social fabric,” says Lily L. Tsai, the Ford Professor of Political Science at MIT.

      Tsai, who is also the director and founder of the MIT Governance LAB (MIT GOV/LAB) and is the current chair of the MIT faculty, is interested in distributive justice — allocating resources fairly across different groups of people. Typically, that might mean splitting resources between different socioeconomic groups, or between different nations. 

      But in an essay in the journal Dædalus, Tsai discusses policies and institutions that consider the needs of people in the future when determining who deserves what resources. That is, they broaden our concept of a collective society to include people who haven’t been born yet and will bear the brunt of climate change in the future.

      Some groups of people do actually consider the needs of future people when making decisions. For example, Wales has a Future Generations Commissioner who monitors whether the government’s actions compromise the needs of future generations. Norway’s Petroleum Fund invests parts of its oil profits for future generations. And MIT’s endowment “is explicitly charged” with ensuring that future students are just as well-off as current students, Tsai says.

      But in other ways, societies place a lower value on the needs of their descendants. For example, to determine the total return on an investment, governments use something called a discount rate that places more value in the present return on the investment than the future return on the investment. And humans are currently using up the planet’s resources at an unsustainable rate, which in turn is raising global temperatures and making earth less habitable for our children and our children’s children.

      The purpose of Tsai’s essay is not to suggest how, say, governments might set discount rates that more fairly consider future people. “I’m interested in the things that make people care about setting the discount rate lower and therefore valuing the future more,” she says. “What are the moral commitments and the kinds of cultural practices or social institutions that make people care more?”

      Tsai thinks the volatility of the modern world and anxiety about the future — say, the future habitability of the planet — make it harder for people to consider the needs of their descendants. In Tsai’s 2021 book “When People Want Punishment,” she argues that this volatility and anxiety make people seek out more stability and order. “The more uncertain the future is, the less you can be sure that saving for the future is going to be valuable to anybody,” she says. So, part of the solution could be making people feel less unsettled and more stable, which Tsai says can be done with institutions we already have, like social welfare systems.

      She also thinks the rate at which things change in the modern world has hurt our ability to consider the long view. “We no longer think in terms of decades and centuries the way in which we used to,” she says.

      MIT GOV/LAB is working with partners to figure out how to experiment in a lab setting with developing democratic practices or institutions that might better distribute resources between current people and future people. That would allow researchers to assess if structuring interactions or decision-making in a particular way encourages people to save more for future people. 

      Tsai thinks getting people to care about their descendants is a problem researchers can work on, and that humans have a natural inclination to consider the future. People have a desire to be entrusted with things of importance, to leave a legacy, and for conservation. “I think many humans actually naturally conserve things that are valuable and scarce, and there’s a strange way in which society has eroded that human instinct in favor of a culture of consumption,” she says. We need to “re-imagine the kinds of practices that encourage conservation rather than consumption,” she adds. More

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      Envisioning education in a climate-changed world

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      What must colleges and universities do differently to help students develop the skills, capacities, and perspectives they’ll need to live, lead, and thrive in a world being remade by the accelerating climate crisis?

      That question was at the heart of a recent convening on MIT’s campus that brought together faculty and staff from more than 30 institutions of higher education. Over two days, attendees delved into the need for higher education to align structurally and philosophically with the changing demands of the coming decades.

      “We all know that there is more to do to educate and to empower today’s students, the young people who rightly feel the threat of climate change most acutely,” said MIT Chancellor Melissa Nobles. “They are our future leaders, the generation that will inherit the full weight of the problem and the responsibility for trying to solve it.”

      The MIT Symposium for Advancing Climate Education, held on April 6 and 7, was hosted by MIT’s Climate Education Working Group, one of three working groups established under the Institute’s ambitious Fast Forward climate action plan. The Climate Education Working Group is tasked with finding ways to strengthen climate- and sustainability-related education at the Institute, from curricular offerings to experiential learning opportunities and beyond.

      “We began working as a group about a year ago, and we quickly realized it would be important to expand the conversation across MIT and to colleagues at other institutions who … are thinking broadly,” says Professor David McGee, co-chair of the Climate Education Working Group.

      Co-chair Professor David Hsu encouraged attendees to build lasting relationships, adding, “There is a true wealth of knowledge spread throughout the room. Every university has pieces of the puzzle, but I don’t think we can point to a single one that right now exemplifies all of what we want to achieve.”

      The symposium featured keynotes by Nobles; Kim Cobb, director of the Institute at Brown for Environment and Society; and Reverend Mariama White-Hammond, founder of the New Roots AME Church in Dorchester, who is also chief of environment, energy, and open space for the City of Boston.

      On the first morning of the event, participants engaged in roundtable discussions, exchanging ideas, successes, and pain points. They also identified and read out close to a dozen unsolved challenges, among them: “How do we meet the fear and anger that students are feeling, and the desire to ‘do’ that students are expressing?” “How do we support people who challenge the status quo?” “As we create these new educational experiences, how do we ensure that a diversity of students can participate in them?” “How do we align tenure and power structures to center communities in the development of this work?” and “How radical a change is MIT willing to make?”

      Kate Trimble, senior associate dean and director of the Office of Experiential Learning, remarked on the thorniness of those questions in closing, wryly adding, “We’ll answer every last one of them before we leave here tomorrow.”

      But in sharing best practices and lessons learned, the tone was overwhelmingly hopeful. Trimble, for example, led a series of discussions highlighting 10 climate education programs already developed at MIT, the University of California at Davis, the University of Michigan, Swarthmore College, Worcester Polytechnic Institute, and McGill University, among others. Each offered new models by which to weave climate justice, community partnerships, and cross-disciplinary teaching into classroom-based and experiential learning.

      Maria Zuber, MIT’s vice president for research, opened the symposium on the second day. Invoking the words of U.N. Secretary-General António Guterres upon publication of the IPCC’s sixth synthesis report last month, she said, “the global response needs to be ‘everything, everywhere, all at once.’”

      She pointed to a number of MIT research initiatives that are structured to address complex problems, among them the Climate Grand Challenges projects — the proposals for which came from researchers across 90 percent of MIT departments — as well as the MIT Climate and Sustainability Consortium and the MIT Energy Initiative’s Future Energy Systems Center.

      “These initiatives recognize that no sector, let alone any single institution, can be effective on its own — and so they seek to engage from the outset with other research institutions and with government, industry, and civil society,” Zuber said.

      Cobb, of Brown University, also spoke about the value of sustained action partnerships built on transdisciplinary research and collaborations with community leaders. She highlighted Brown’s participation in the Breathe Providence project and Georgia Tech’s involvement in the Smart Sea Level Sensors project in Savannah.

      Several speakers noted the importance of hands-on learning opportunities for students as a training ground for tackling complex challenges at scale. Students should learn how to build a respectfully collaborative team and how to connect with communities to understand the true nature and constraints of the problem, they said.

      Engineering professor Anne White, who is co-chair of the MIT Climate Nucleus, the faculty committee charged with implementing the Fast Forward plan, and MIT’s associate provost and associate vice president for research administration, moderated a career panel spanning nonprofit and corporate roles.

      The panelists’ experiences emphasized that in a world where no sector will be untouched by the impacts of climate change, every graduate in every field must be informed and ready to engage.

      “Education is training; it’s skills. We want the students to be smart. But what I’m hearing is that it’s not just that,” White reflected. “It’s these other qualities, right? It’s can they be brave … and can they be kind?”

      “Every job is a climate job in this era,” declared MIT graduate student Dyanna Jaye, co-founder of the Sunrise Movement.

      John Fernández, director of the Environmental Solutions Initiative at MIT, moderated a panel on structural change in higher education, speaking with Jim Stock, vice provost for climate and sustainability at Harvard University; Toddi Steelman, dean of the Nicholas School of the Environment at Duke University; and Stephen Porder, assistant provost for sustainability at Brown.

      Steelman (who is also a qualified wildland firefighter — a useful skill for a dean, she noted) described a popular course at Duke called “Let’s Talk About Climate Change” that is jointly taught by a biogeochemist and a theologian. The course enrolled around 150 students in the fall who met for contemplative breakout discussions. “Unless we talk about our hearts and our minds,” she said, “we’re not going to make progress.”

      White-Hammond highlighted one trait she believes today’s students already have in abundance.

      “They’re willing to say that the status quo is unacceptable, and that is an important part of being courageous in the face of this climate crisis,” she said. She urged institutions to take that cue.

      “If we have to remake the world, rebuild it on something radically different. Why would we bake in racial injustice again? Why would we say, let’s have an equally unequal economic system that just doesn’t burn as many fossil fuels? I think we have an opportunity to go big.”

      “That,” she added, “is the work I believe higher education should be taking on, and not from an ivory tower, but rooted in real communities.”

      The MIT Symposium for Advancing Climate Education was part of Earth Month at MIT, a series of climate and sustainability events on campus in April. More