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    Harnessing synthetic biology to make sustainable alternatives to petroleum products

    Reducing our reliance on fossil fuels is going to require a transformation in the way we make things. That’s because the hydrocarbons found in fuels like crude oil, natural gas, and coal are also in everyday items like plastics, clothing, and cosmetics.

    Now Visolis, founded by Deepak Dugar SM ’11, MBA ’13, PhD ’13, is combining synthetic biology with chemical catalysis to reinvent the way the world makes things — and reducing gigatons of greenhouse gas emissions in the process.

    The company — which uses a microbe to ferment biomass waste like wood chips and create a molecular building block called mevalonic acid — is more sustainably producing everything from car tires and cosmetics to aviation fuels by tweaking the chemical processes involved to make different byproducts.

    “We started with [the rubber component] isoprene as the main molecule we produce [from mevalonic acid], but we’ve expanded our platform with this unique combination of chemistry and biology that allows us to decarbonize multiple supply chains very rapidly and efficiently,” Dugar explains. “Imagine carbon-negative yoga pants. We can make that happen. Tires can be carbon-negative, personal care can lower its footprint — and we’re already selling into personal care. So in everything from personal care to apparel to industrial goods, our platform is enabling decarbonization of manufacturing.”

    “Carbon-negative” is a term Dugar uses a lot. Visolis has already partnered with some of the world’s largest consumers of isoprene, a precursor to rubber, and now Dugar wants to prove out the company’s process in other emissions-intensive industries.

    “Our process is carbon-negative because plants are taking CO2 from the air, and we take that plant matter and process it into something structural, like synthetic rubber, which is used for things like roofing, tires, and other applications,” Dugar explains. “Generally speaking, most of that material at the end of its life gets recycled, for example to tarmac or road, or, worst-case scenario, it ends up in a landfill, so the CO2 that was captured by the plant matter stays captured in the materials. That means our production can be carbon-negative depending on the emissions of the production process. That allows us to not only reduce climate change but start reversing it. That was an insight I had about 10 years ago at MIT.”

    Finding a path

    For his PhD, Dugar explored the economics of using microbes to make high-octane gas additives. He also took classes at the MIT Sloan School of Management on sustainability and entrepreneurship, including the particularly influential course 15.366 (Climate and Energy Ventures). The experience inspired him to start a company.

    “I wanted to work on something that could have the largest climate impact, and that was replacing petroleum,” Dugar says. “It was about replacing petroleum not just as a fuel but as a material as well. Everything from the clothes we wear to the furniture we sit on is often made using petroleum.”

    By analyzing recent advances in synthetic biology and making some calculations from first principles, Dugar decided that a microbial approach to cleaning up the production of rubber was viable. He participated in the MIT Clean Energy Prize and worked with others at MIT to prove out the idea. But it was still just an idea. After graduation, he took a consulting job at a large company, spending his nights and weekends renting lab space to continue trying to make his sustainable rubber a reality.

    After 18 months, by applying engineering concepts like design-for-scale to synthetic biology, Dugar was able to develop a microbe that met 80 percent of his criteria for making an intermediate molecule called mevalonic acid. From there, he developed a chemical catalysis process that converted mevalonic acid to isoprene, the main component of natural rubber. Visolis has since patented other chemical conversion processes that turn mevalonic acid to aviation fuel, polymers, and fabrics.

    Dugar left his consulting job in 2014 and was awarded a fellowship to work on Visolis full-time at the Lawrence Berkeley National Lab via Activate, an incubator empowering scientists to reinvent the world.

    From rubber to jet fuels

    Today, in addition to isoprene, Visolis is selling skin care products through the brand Ameva Bio, which produces mevalonic acid-based creams by recycling plant byproducts created in other processes. The company offers refillable bottles and even offsets emissions from the shipping of its products.

    “We are working throughout the supply chain,” Dugar says. “It made sense to clean up the isoprene part of the rubber supply chain rather than the entire supply chain. But we’re also producing molecules for skin that are better for you, so you can put something much more sustainable and healthier on your body instead of petrochemicals. We launched Ameva to demonstrate that brands can leverage synthetic biology to turn carbon-negative ingredients into high-performing products.”

    Visolis is also starting the process of gaining regulatory approval for its sustainable aviation fuel, which Dugar believes could have the biggest climate impact of any of the company’s products by cleaning up the production of fuels for commercial flight.

    “We’re working with leading companies to help them decarbonize aviation” Dugar says. “If you look at the lifecycle of fuel, the current petroleum-based approach is we dig out hydrocarbons from the ground and burn it, emitting CO2 into the air. In our process, we take plant matter, which affixes to CO2 and captures renewable energy in those bonds, and then we transfer that into aviation fuel plus things like synthetic rubber, yoga pants, and other things that continue to hold the carbon. So, our factories can still operate at net zero carbon emissions.”

    Visolis is already generating millions of dollars in revenue, and Dugar says his goal is to scale the company rapidly now that its platform molecule has been validated.

    “We have been scaling our technology by 10 times every two to three years and are now looking to increase deployment of our technology at the same pace, which is very exciting.” Dugar says. “If you extrapolate that, very quickly you get to massive impact. That’s our goal.” More

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    Cutting urban carbon emissions by retrofitting buildings

    To support the worldwide struggle to reduce carbon emissions, many cities have made public pledges to cut their carbon emissions in half by 2030, and some have promised to be carbon neutral by 2050. Buildings can be responsible for more than half a municipality’s carbon emissions. Today, new buildings are typically designed in ways that minimize energy use and carbon emissions. So attention focuses on cleaning up existing buildings.

    A decade ago, leaders in some cities took the first step in that process: They quantified their problem. Based on data from their utilities on natural gas and electricity consumption and standard pollutant-emission rates, they calculated how much carbon came from their buildings. They then adopted policies to encourage retrofits, such as adding insulation, switching to double-glazed windows, or installing rooftop solar panels. But will those steps be enough to meet their pledges?

    “In nearly all cases, cities have no clear plan for how they’re going to reach their goal,” says Christoph Reinhart, a professor in the Department of Architecture and director of the Building Technology Program. “That’s where our work comes in. We aim to help them perform analyses so they can say, ‘If we, as a community, do A, B, and C to buildings of a certain type within our jurisdiction, then we are going to get there.’”

    To support those analyses, Reinhart and a team in the MIT Sustainable Design Lab (SDL) — PhD candidate Zachary M. Berzolla SM ’21; former doctoral student Yu Qian Ang PhD ’22, now a research collaborator at the SDL; and former postdoc Samuel Letellier-Duchesne, now a senior building performance analyst at the international building engineering and consulting firm Introba — launched a publicly accessible website providing a series of simulation tools and a process for using them to determine the impacts of planned steps on a specific building stock. Says Reinhart: “The takeaway can be a clear technology pathway — a combination of building upgrades, renewable energy deployments, and other measures that will enable a community to reach its carbon-reduction goals for their built environment.”

    Analyses performed in collaboration with policymakers from selected cities around the world yielded insights demonstrating that reaching current goals will require more effort than city representatives and — in a few cases — even the research team had anticipated.

    Exploring carbon-reduction pathways

    The researchers’ approach builds on a physics-based “building energy model,” or BEM, akin to those that architects use to design high-performance green buildings. In 2013, Reinhart and his team developed a method of extending that concept to analyze a cluster of buildings. Based on publicly available geographic information system (GIS) data, including each building’s type, footprint, and year of construction, the method defines the neighborhood — including trees, parks, and so on — and then, using meteorological data, how the buildings will interact, the airflows among them, and their energy use. The result is an “urban building energy model,” or UBEM, for a neighborhood or a whole city.

    The website developed by the MIT team enables neighborhoods and cities to develop their own UBEM and to use it to calculate their current building energy use and resulting carbon emissions, and then how those outcomes would change assuming different retrofit programs or other measures being implemented or considered. “The website — UBEM.io — provides step-by-step instructions and all the simulation tools that a team will need to perform an analysis,” says Reinhart.

    The website starts by describing three roles required to perform an analysis: a local sustainability champion who is familiar with the municipality’s carbon-reduction efforts; a GIS manager who has access to the municipality’s urban datasets and maintains a digital model of the built environment; and an energy modeler — typically a hired consultant — who has a background in green building consulting and individual building energy modeling.

    The team begins by defining “shallow” and “deep” building retrofit scenarios. To explain, Reinhart offers some examples: “‘Shallow’ refers to things that just happen, like when you replace your old, failing appliances with new, energy-efficient ones, or you install LED light bulbs and weatherstripping everywhere,” he says. “‘Deep’ adds to that list things you might do only every 20 years, such as ripping out walls and putting in insulation or replacing your gas furnace with an electric heat pump.”

    Once those scenarios are defined, the GIS manager uploads to UBEM.io a dataset of information about the city’s buildings, including their locations and attributes such as geometry, height, age, and use (e.g., commercial, retail, residential). The energy modeler then builds a UBEM to calculate the energy use and carbon emissions of the existing building stock. Once that baseline is established, the energy modeler can calculate how specific retrofit measures will change the outcomes.

    Workshop to test-drive the method

    Two years ago, the MIT team set up a three-day workshop to test the website with sample users. Participants included policymakers from eight cities and municipalities around the world: namely, Braga (Portugal), Cairo (Egypt), Dublin (Ireland), Florianopolis (Brazil), Kiel (Germany), Middlebury (Vermont, United States), Montreal (Canada), and Singapore. Taken together, the cities represent a wide range of climates, socioeconomic demographics, cultures, governing structures, and sizes.

    Working with the MIT team, the participants presented their goals, defined shallow- and deep-retrofit scenarios for their city, and selected a limited but representative area for analysis — an approach that would speed up analyses of different options while also generating results valid for the city as a whole.

    They then performed analyses to quantify the impacts of their retrofit scenarios. Finally, they learned how best to present their findings — a critical part of the exercise. “When you do this analysis and bring it back to the people, you can say, ‘This is our homework over the next 30 years. If we do this, we’re going to get there,’” says Reinhart. “That makes you part of the community, so it’s a joint goal.”

    Sample results

    After the close of the workshop, Reinhart and his team confirmed their findings for each city and then added one more factor to the analyses: the state of the city’s electric grid. Several cities in the study had pledged to make their grid carbon-neutral by 2050. Including the grid in the analysis was therefore critical: If a building becomes all-electric and purchases its electricity from a carbon-free grid, then that building will be carbon neutral — even with no on-site energy-saving retrofits.

    The final analysis for each city therefore calculated the total kilograms of carbon dioxide equivalent emitted per square meter of floor space assuming the following scenarios: the baseline; shallow retrofit only; shallow retrofit plus a clean electricity grid; deep retrofit only; deep retrofit plus rooftop photovoltaic solar panels; and deep retrofit plus a clean electricity grid. (Note that “clean electricity grid” is based on the area’s most ambitious decarbonization target for their power grid.)

    The following paragraphs provide highlights of the analyses for three of the eight cities. Included are the city’s setting, emission-reduction goals, current and proposed measures, and calculations of how implementation of those measures would affect their energy use and carbon emissions.

    Singapore

    Singapore is generally hot and humid, and its building energy use is largely in the form of electricity for cooling. The city is dominated by high-rise buildings, so there’s not much space for rooftop solar installations to generate the needed electricity. Therefore, plans for decarbonizing the current building stock must involve retrofits. The shallow-retrofit scenario focuses on installing energy-efficient lighting and appliances. To those steps, the deep-retrofit scenario adds adopting a district cooling system. Singapore’s stated goals are to cut the baseline carbon emissions by about a third by 2030 and to cut it in half by 2050.

    The analysis shows that, with just the shallow retrofits, Singapore won’t achieve its 2030 goal. But with the deep retrofits, it should come close. Notably, decarbonizing the electric grid would enable Singapore to meet and substantially exceed its 2050 target assuming either retrofit scenario.

    Dublin

    Dublin has a mild climate with relatively comfortable summers but cold, humid winters. As a result, the city’s energy use is dominated by fossil fuels, in particular, natural gas for space heating and domestic hot water. The city presented just one target — a 40 percent reduction by 2030.

    Dublin has many neighborhoods made up of Georgian row houses, and, at the time of the workshop, the city already had a program in place encouraging groups of owners to insulate their walls. The shallow-retrofit scenario therefore focuses on weatherization upgrades (adding weatherstripping to windows and doors, insulating crawlspaces, and so on). To that list, the deep-retrofit scenario adds insulating walls and installing upgraded windows. The participants didn’t include electric heat pumps, as the city was then assessing the feasibility of expanding the existing district heating system.

    Results of the analyses show that implementing the shallow-retrofit scenario won’t enable Dublin to meet its 2030 target. But the deep-retrofit scenario will. However, like Singapore, Dublin could make major gains by decarbonizing its electric grid. The analysis shows that a decarbonized grid — with or without the addition of rooftop solar panels where possible — could more than halve the carbon emissions that remain in the deep-retrofit scenario. Indeed, a decarbonized grid plus electrification of the heating system by incorporating heat pumps could enable Dublin to meet a future net-zero target.

    Middlebury

    Middlebury, Vermont, has warm, wet summers and frigid winters. Like Dublin, its energy demand is dominated by natural gas for heating. But unlike Dublin, it already has a largely decarbonized electric grid with a high penetration of renewables.

    For the analysis, the Middlebury team chose to focus on an aging residential neighborhood similar to many that surround the city core. The shallow-retrofit scenario calls for installing heat pumps for space heating, and the deep-retrofit scenario adds improvements in building envelopes (the façade, roof, and windows). The town’s targets are a 40 percent reduction from the baseline by 2030 and net-zero carbon by 2050.

    Results of the analyses showed that implementing the shallow-retrofit scenario won’t achieve the 2030 target. The deep-retrofit scenario would get the city to the 2030 target but not to the 2050 target. Indeed, even with the deep retrofits, fossil fuel use remains high. The explanation? While both retrofit scenarios call for installing heat pumps for space heating, the city would continue to use natural gas to heat its hot water.

    Lessons learned

    For several policymakers, seeing the results of their analyses was a wake-up call. They learned that the strategies they had planned might not be sufficient to meet their stated goals — an outcome that could prove publicly embarrassing for them in the future.

    Like the policymakers, the researchers learned from the experience. Reinhart notes three main takeaways.

    First, he and his team were surprised to find how much of a building’s energy use and carbon emissions can be traced to domestic hot water. With Middlebury, for example, even switching from natural gas to heat pumps for space heating didn’t yield the expected effect: On the bar graphs generated by their analyses, the gray bars indicating carbon from fossil fuel use remained. As Reinhart recalls, “I kept saying, ‘What’s all this gray?’” While the policymakers talked about using heat pumps, they were still going to use natural gas to heat their hot water. “It’s just stunning that hot water is such a big-ticket item. It’s huge,” says Reinhart.

    Second, the results demonstrate the importance of including the state of the local electric grid in this type of analysis. “Looking at the results, it’s clear that if we want to have a successful energy transition, the building sector and the electric grid sector both have to do their homework,” notes Reinhart. Moreover, in many cases, reaching carbon neutrality by 2050 would require not only a carbon-free grid but also all-electric buildings.

    Third, Reinhart was struck by how different the bar graphs presenting results for the eight cities look. “This really celebrates the uniqueness of different parts of the world,” he says. “The physics used in the analysis is the same everywhere, but differences in the climate, the building stock, construction practices, electric grids, and other factors make the consequences of making the same change vary widely.”

    In addition, says Reinhart, “there are sometimes deeply ingrained conflicts of interest and cultural norms, which is why you cannot just say everybody should do this and do this.” For instance, in one case, the city owned both the utility and the natural gas it burned. As a result, the policymakers didn’t consider putting in heat pumps because “the natural gas was a significant source of municipal income, and they didn’t want to give that up,” explains Reinhart.

    Finally, the analyses quantified two other important measures: energy use and “peak load,” which is the maximum electricity demanded from the grid over a specific time period. Reinhart says that energy use “is probably mostly a plausibility check. Does this make sense?” And peak load is important because the utilities need to keep a stable grid.

    Middlebury’s analysis provides an interesting look at how certain measures could influence peak electricity demand. There, the introduction of electric heat pumps for space heating more than doubles the peak demand from buildings, suggesting that substantial additional capacity would have to be added to the grid in that region. But when heat pumps are combined with other retrofitting measures, the peak demand drops to levels lower than the starting baseline.

    The aftermath: An update

    Reinhart stresses that the specific results from the workshop provide just a snapshot in time; that is, where the cities were at the time of the workshop. “This is not the fate of the city,” he says. “If we were to do the same exercise today, we’d no doubt see a change in thinking, and the outcomes would be different.”

    For example, heat pumps are now familiar technology and have demonstrated their ability to handle even bitterly cold climates. And in some regions, they’ve become economically attractive, as the war in Ukraine has made natural gas both scarce and expensive. Also, there’s now awareness of the need to deal with hot water production.

    Reinhart notes that performing the analyses at the workshop did have the intended impact: It brought about change. Two years after the project had ended, most of the cities reported that they had implemented new policy measures or had expanded their analysis across their entire building stock. “That’s exactly what we want,” comments Reinhart. “This is not an academic exercise. It’s meant to change what people focus on and what they do.”

    Designing policies with socioeconomics in mind

    Reinhart notes a key limitation of the UBEM.io approach: It looks only at technical feasibility. But will the building owners be willing and able to make the energy-saving retrofits? Data show that — even with today’s incentive programs and subsidies — current adoption rates are only about 1 percent. “That’s way too low to enable a city to achieve its emission-reduction goals in 30 years,” says Reinhart. “We need to take into account the socioeconomic realities of the residents to design policies that are both effective and equitable.”

    To that end, the MIT team extended their UBEM.io approach to create a socio-techno-economic analysis framework that can predict the rate of retrofit adoption throughout a city. Based on census data, the framework creates a UBEM that includes demographics for the specific types of buildings in a city. Accounting for the cost of making a specific retrofit plus financial benefits from policy incentives and future energy savings, the model determines the economic viability of the retrofit package for representative households.

    Sample analyses for two Boston neighborhoods suggest that high-income households are largely ineligible for need-based incentives or the incentives are insufficient to prompt action. Lower-income households are eligible and could benefit financially over time, but they don’t act, perhaps due to limited access to information, a lack of time or capital, or a variety of other reasons.

    Reinhart notes that their work thus far “is mainly looking at technical feasibility. Next steps are to better understand occupants’ willingness to pay, and then to determine what set of federal and local incentive programs will trigger households across the demographic spectrum to retrofit their apartments and houses, helping the worldwide effort to reduce carbon emissions.”

    This work was supported by Shell through the MIT Energy Initiative. Zachary Berzolla was supported by the U.S. National Science Foundation Graduate Research Fellowship. Samuel Letellier-Duchesne was supported by the postdoctoral fellowship of the Natural Sciences and Engineering Research Council of Canada.

    This article appears in the Spring 2023 issue of Energy Futures, the magazine of the MIT Energy Initiative. More

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    Study: The ocean’s color is changing as a consequence of climate change

    The ocean’s color has changed significantly over the last 20 years, and the global trend is likely a consequence of human-induced climate change, report scientists at MIT, the National Oceanography Center in the U.K., and elsewhere.  

    In a study appearing today in Nature, the team writes that they have detected changes in ocean color over the past two decades that cannot be explained by natural, year-to-year variability alone. These color shifts, though subtle to the human eye, have occurred over 56 percent of the world’s oceans — an expanse that is larger than the total land area on Earth.

    In particular, the researchers found that tropical ocean regions near the equator have become steadily greener over time. The shift in ocean color indicates that ecosystems within the surface ocean must also be changing, as the color of the ocean is a literal reflection of the organisms and materials in its waters.

    At this point, the researchers cannot say how exactly marine ecosystems are changing to reflect the shifting color. But they are pretty sure of one thing: Human-induced climate change is likely the driver.

    “I’ve been running simulations that have been telling me for years that these changes in ocean color are going to happen,” says study co-author Stephanie Dutkiewicz, senior research scientist in MIT’s Department of Earth, Atmospheric and Planetary Sciences and the Center for Global Change Science. “To actually see it happening for real is not surprising, but frightening. And these changes are consistent with man-induced changes to our climate.”

    “This gives additional evidence of how human activities are affecting life on Earth over a huge spatial extent,” adds lead author B. B. Cael PhD ’19 of the National Oceanography Center in Southampton, U.K. “It’s another way that humans are affecting the biosphere.”

    The study’s co-authors also include Stephanie Henson of the National Oceanography Center, Kelsey Bisson at Oregon State University, and Emmanuel Boss of the University of Maine.

    Above the noise

    The ocean’s color is a visual product of whatever lies within its upper layers. Generally, waters that are deep blue reflect very little life, whereas greener waters indicate the presence of ecosystems, and mainly phytoplankton — plant-like microbes that are abundant in upper ocean and that contain the green pigment chlorophyll. The pigment helps plankton harvest sunlight, which they use to capture carbon dioxide from the atmosphere and convert it into sugars.

    Phytoplankton are the foundation of the marine food web that sustains progressively more complex organisms, on up to krill, fish, and seabirds and marine mammals. Phytoplankton are also a powerful muscle in the ocean’s ability to capture and store carbon dioxide. Scientists are therefore keen to monitor phytoplankton across the surface oceans and to see how these essential communities might respond to climate change. To do so, scientists have tracked changes in chlorophyll, based on the ratio of how much blue versus green light is reflected from the ocean surface, which can be monitored from space

    But around a decade ago, Henson, who is a co-author of the current study, published a paper with others, which showed that, if scientists were tracking chlorophyll alone, it would take at least 30 years of continuous monitoring to detect any trend that was driven specifically by climate change. The reason, the team argued, was that the large, natural variations in chlorophyll from year to year would overwhelm any anthropogenic influence on chlorophyll concentrations. It would therefore take several decades to pick out a meaningful, climate-change-driven signal amid the normal noise.

    In 2019, Dutkiewicz and her colleagues published a separate paper, showing through a new model that the natural variation in other ocean colors is much smaller compared to that of chlorophyll. Therefore, any signal of climate-change-driven changes should be easier to detect over the smaller, normal variations of other ocean colors. They predicted that such changes should be apparent within 20, rather than 30 years of monitoring.

    “So I thought, doesn’t it make sense to look for a trend in all these other colors, rather than in chlorophyll alone?” Cael says. “It’s worth looking at the whole spectrum, rather than just trying to estimate one number from bits of the spectrum.”

     The power of seven

    In the current study, Cael and the team analyzed measurements of ocean color taken by the Moderate Resolution Imaging Spectroradiometer (MODIS) aboard the Aqua satellite, which has been monitoring ocean color for 21 years. MODIS takes measurements in seven visible wavelengths, including the two colors researchers traditionally use to estimate chlorophyll.

    The differences in color that the satellite picks up are too subtle for human eyes to differentiate. Much of the ocean appears blue to our eye, whereas the true color may contain a mix of subtler wavelengths, from blue to green and even red.

    Cael carried out a statistical analysis using all seven ocean colors measured by the satellite from 2002 to 2022 together. He first looked at how much the seven colors changed from region to region during a given year, which gave him an idea of their natural variations. He then zoomed out to see how these annual variations in ocean color changed over a longer stretch of two decades. This analysis turned up a clear trend, above the normal year-to-year variability.

    To see whether this trend is related to climate change, he then looked to Dutkiewicz’s model from 2019. This model simulated the Earth’s oceans under two scenarios: one with the addition of greenhouse gases, and the other without it. The greenhouse-gas model predicted that a significant trend should show up within 20 years and that this trend should cause changes to ocean color in about 50 percent of the world’s surface oceans — almost exactly what Cael found in his analysis of real-world satellite data.

    “This suggests that the trends we observe are not a random variation in the Earth system,” Cael says. “This is consistent with anthropogenic climate change.”

    The team’s results show that monitoring ocean colors beyond chlorophyll could give scientists a clearer, faster way to detect climate-change-driven changes to marine ecosystems.

    “The color of the oceans has changed,” Dutkiewicz says. “And we can’t say how. But we can say that changes in color reflect changes in plankton communities, that will impact everything that feeds on plankton. It will also change how much the ocean will take up carbon, because different types of plankton have different abilities to do that. So, we hope people take this seriously. It’s not only models that are predicting these changes will happen. We can now see it happening, and the ocean is changing.”

    This research was supported, in part, by NASA. More

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    MIT welcomes Brian Deese as its next Institute Innovation Fellow

    MIT has appointed former White House National Economic Council (NEC) director Brian Deese as an MIT Innovation Fellow, focusing on the impact of economic policies that strengthen the United States’ industrial capacity and on accelerating climate investment and innovation. Deese will begin his appointment this summer. 

    “From climate change to U.S. industrial strategy, the people of MIT strive to make serious positive change at scale — and in Brian Deese, we have found a brilliant ally, guide, and inspiration,“ says MIT President Sally Kornbluth. “He pairs an easy command of technological questions with a rare grasp of contemporary policy and the politics it takes for such policies to succeed. We are extremely fortunate to have Brian with us for this pivotal year.” 

    Deese is an accomplished public policy innovator. As President Joe Biden’s top economic advisor, he was instrumental in shaping several pieces of legislation — the bipartisan Infrastructure Investment and Jobs Act, the CHIPS and Science Act, and the Inflation Reduction Act  — that together are expected to yield more than $3 trillion over the next decade in public and private investments in physical infrastructure, semiconductors, and clean energy, as well as a major expansion of scientific research. 

    “I was attracted to MIT by its combination of extraordinary capabilities in engineering, science, and economics, and the desire and enthusiasm to translate those capabilities into real-world outcomes,” says Deese. 

    Climate and economic policy expertise

    Deese’s public service career has spanned multiple periods of global economic crisis. He has helped shape policies ranging from clean energy infrastructure investments to addressing supply chain disruptions triggered by the pandemic and the war in Ukraine. 

    As NEC director in the Biden White House, Deese oversaw the development of domestic and international economic policy. Previously, he served as the global head of sustainable investing at BlackRock, Inc., one of the world’s leading asset management firms; before that, he held several key posts in the Obama White House, serving as the president’s top advisor on climate policy; deputy director of the Office of Management and Budget; and deputy director of the NEC. Early in the Obama Administration, Deese played a key role in developing and implementing the rescue of the U.S. auto industry during the Great Recession. Deese earned a bachelor of arts degree from Middlebury College and his JD from Yale Law School.

    Despite recent legislative progress, the world still faces daunting climate and energy challenges, including the need to reduce greenhouse gas emissions, increase energy capacity, and fill infrastructure gaps, Deese notes.

    “Our biggest challenge is our biggest opportunity,” he says. “We need to build at a speed not seen in generations.”  

    Deese is also thinking about how to effectively design and implement industrial strategy approaches that build on recent efforts to restore the U.S. semiconductor industry. What’s needed, he says, is an approach that can foster innovation and build manufacturing capacity — especially in economically disadvantaged areas of the country — while learning lessons from previous successes and failures in this field. 

    “This is a timely and important appointment because Brian has enormous experience at the top levels of government in shaping public policies for climate, technology, manufacturing, and energy, and the consequences for  shared prosperity nationally and globally — all subjects of intense interest to the MIT community,” says MIT Associate Provost Richard Lester. “I fully expect that faculty and student engagement with Brian while he is with us will help advance MIT research, innovation, and impact in these critical areas.”

    Innovation fellowship

    Previous MIT Innovation Fellows, typically in residence for a year or more, have included luminaries from industry and government, including most recently Virginia M. “Ginny” Rometty, former chair, president, and CEO of IBM; Eric Schmidt, former executive chair of Google’s parent company, Alphabet; the late Ash Carter, former U.S. secretary of defense; and former Massachusetts Governor Deval Patrick.

    During his time at MIT, Deese will work on a project detailing and mapping private investment in clean energy and other climate-related activities. He will also interact with students, staff, and faculty from across the Institute. 

    “I hope my role at MIT can largely be about forging partnerships within the Institute and outside of the Institute to significantly reduce the time between innovation and outcomes into the world,” says Deese. More

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    MIT climate and sustainability interns consider aviation emissions and climate change

    Over 600 MIT students are traveling abroad with the MIT International Science and Technology Initiatives (MISTI) to intern, research, and work in organizations across 25 countries this summer. Twenty percent of the students were placed in areas related to climate and sustainability.

    Through MISTI, hundreds of MIT students travel abroad each summer to intern in companies, universities, governments, and nongovernmental organizations. Since 2018, around 20 percent of the internships and research experiences have been in areas related to climate and sustainability. MISTI has been working to increase the number of interns working on these projects by increasing the number of hosts and available grants, as well as connecting with other labs, departments, and centers across MIT to support students’ global experiences.

    For the first time this year, MISTI developed pre-departure sessions intended to help students reflect on their experiences in the wider context of sustainability and climate change. Around 90 students were invited to participate in a Canvas course and an in-person session with guest speakers. In the Canvas session, students were asked to calculate the carbon footprint of their flight to their MISTI destination and compare the results to other common daily activities. Four out of five of them expressed that the level of emissions from their flights was higher, or much higher, than they previously thought. Half of the students expressed that this was the first time they thought about their flight emissions for the summer. The students were then directed to the MIT Climate Portal website and asked to reflect on the impact of carbon dioxide emissions on the climate and the effects of climate change on economically developing countries. The Canvas exercise concluded with readings and reflections on what can be done to address the climate crisis.

    The in-person session featured David Hsu, associate professor of urban and environmental planning and co-chair of the Campus Fast Forward working group on climate education, who presented his research and work on flight emissions. He emphasized the high impact of aviation on carbon dioxide emissions and how emissions are unevenly distributed on a global scale, based on income levels and per capita bases. A small group of travelers account for most of the emissions, which is also true in academic settings where a small number of travelers have a much higher carbon footprint. Hsu also explained the School of Architecture and Planning climate action plan and how it addresses faculty and student travel. “I know it’s hard. If we at MIT want to be leaders in this area, talking about it is not enough,” he said. “We have to act. We cannot be models just by doing research; we have to be role models at all levels. Faculty, staff, and students have to change their flight habits.”

    Having completed the climate and sustainability training, Favianna Colón Irizarry, a rising second-year majoring in chemical and biological engineering, explains, “to minimize our carbon footprint, we are taught to eat consciously and use environmentally friendly products. What we are not taught is that this alone will not make a difference; we ought to sacrifice more, like flying selectively and meaningfully, to truly make an impact. MISTI’s Climate and Sustainability helped me recognize this, as well as prepare me for how I choose to proceed in my future green endeavors.”

    Also during the session, rising seniors Anushree Chaudhuri and Melissa Stok, the leads for the MIT Student Sustainability Coalition, presented their work around coordinating efforts among students and the vast landscape of groups, organizations, and entities at the Institute. They invited all interested students to join and reach out to any of the entities that could be a good fit for their interests. Chaudhuri reflected afterwards, “Sustainability is inherently interdisciplinary. Every MIT student can incorporate sustainability into their work, regardless of major, class year, or interests! I was excited to join my SSC co-lead, Melissa, in speaking with a diverse group of MISTI interns about how to explore sustainability-related academic, extracurricular, professional, and experiential opportunities at MIT and beyond. These students come from many different disciplines, so it was incredibly heartening to hear that they are all pursuing a climate-related project abroad this summer.”

    Eduardo Rivera, MISTI’s coordinator for climate and sustainability expressed that “educational experiences abroad are a fundamental part of MIT’s mission to foster global leaders to tackle the climate crisis. This summer, more than 110 students will be working around the world in solar and wind technologies, carbon capture, climate adaptation and urban planning, sustainable concrete, electric mobility, among others. We are using this opportunity to expand on the reflection part of the experiential learning cycle. The goal of these pre-departure sessions is to raise awareness and help our students reflect on the impact of their everyday activities on the climate, and to also give them resources to learn and act thoughtfully. We hope they will not only become conscious travelers, but also agents for change.”

    “This year’s climate and sustainability pre-departure training were pilot sessions, and the goal is to expand this learning experience to all MISTI students, not just those working in the fields of climate and sustainability. This will be a unique opportunity to raise awareness and expand the knowledge to over 1,000 of our students as they travel to more than 40 countries across the globe,” explains Abby MacKenzie, MIT-India coordinator who co-developed the pre-departure sessions. More

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    Panel addresses technologies needed for a net-zero future

    Five speakers at a recent public panel discussion hosted by the MIT Energy Initiative (MITEI) and introduced by Deputy Director for Science and Technology Robert Stoner tackled one of the thorniest, yet most critical, questions facing the world today: How can we achieve the ambitious goals set by governments around the globe, including the United States, to reach net zero emissions of greenhouse gases by mid-century?

    While the challenges are great, the panelists agreed, there is reason for optimism that these technological challenges can be solved. More uncertain, some suggested, are the social, economic, and political hurdles to bringing about the needed innovations.

    The speakers addressed areas where new or improved technologies or systems are needed if these ambitious goals are to be achieved. Anne White, aassociate provost and associate vice president for research administration and a professor of nuclear science and engineering at MIT, moderated the panel discussion. She said that achieving the ambitious net-zero goal “has to be accomplished by filling some gaps, and going after some opportunities.” In addressing some of these needs, she said the five topics chosen for the panel discussion were “places where MIT has significant expertise, and progress is already ongoing.”

    First of these was the heating and cooling of buildings. Christoph Reinhart, a professor of architecture and director of the Building Technology Program, said that currently about 1 percent of existing buildings are being retrofitted each year for energy efficiency and conversion from fossil-fuel heating systems to efficient electric ones — but that is not nearly enough to meet the 2050 net-zero target. “It’s an enormous task,” he said. To meet the goals, he said, would require increasing the retrofitting rate to 5 percent per year, and to require all new construction to be carbon neutral as well.

    Reinhart then showed a series of examples of how such conversions could take place using existing solar and heat pump technology, and depending on the configuration, how they could provide a payback to the homeowner within 10 years or less. However, without strong policy incentives the initial cost outlay for such a system, on the order of $50,000, is likely to put conversions out of reach of many people. Still, a recent survey found that 30 percent of homeowners polled said they would accept installation at current costs. While there is government money available for incentives for others, “we have to be very clever on how we spend all this money … and make sure that everybody is basically benefiting.”

    William Green, a professor of chemical engineering, spoke about the daunting challenge of bringing aviation to net zero. “More and more people like to travel,” he said, but that travel comes with carbon emissions that affect the climate, as well as air pollution that affects human health. The economic costs associated with these emissions, he said, are estimated at $860 per ton of jet fuel used — which is very close to the cost of the fuel itself. So the price paid by the airlines, and ultimately by the passengers, “is only about half of the true cost to society, and the other half is being borne by all of us, by the fact that it’s affecting the climate and it’s causing medical problems for people.”

    Eliminating those emissions is a major challenge, he said. Virtually all jet fuel today is fossil fuel, but airlines are starting to incorporate some biomass-based fuel, derived mostly from food waste. But even these fuels are not carbon-neutral, he said. “They actually have pretty significant carbon intensity.”

    But there are possible alternatives, he said, mostly based on using hydrogen produced by clean electricity, and making fuels out of that hydrogen by reacting it, for example, with carbon dioxide. This could indeed produce a carbon-neutral fuel that existing aircraft could use, but the process is costly, requiring a great deal of hydrogen, and ways of concentrating carbon dioxide. Other viable options also exist, but all would add significant expense, at least with present technology. “It’s going to cost a lot more for the passengers on the plane,” Green said, “But the society will benefit from that.”

    Increased electrification of heating and transportation in order to avoid the use of fossil fuels will place major demands on the existing electric grid systems, which have to perform a constant delicate balancing of production with demand. Anuradha Annaswamy, a senior research scientist in MIT’s mechanical engineering department, said “the electric grid is an engineering marvel.” In the United States it consists of 300,000 miles of transmission lines capable of carrying 470,000 megawatts of power.

    But with a projected doubling of energy from renewable sources entering the grid by 2030, and with a push to electrify everything possible — from transportation to buildings to industry — the load is not only increasing, but the patterns of both energy use and production are changing. Annaswamy said that “with all these new assets and decision-makers entering the picture, the question is how you can use a more sophisticated information layer that coordinates how all these assets are either consuming or producing or storing energy, and have that information layer coexist with the physical layer to make and deliver electricity in all these ways. It’s really not a simple problem.”

    But there are ways of addressing these complexities. “Certainly, emerging technologies in power electronics and control and communication can be leveraged,” she said. But she added that “This is not just a technology problem, really, it is something that requires technologists, economists, and policymakers to all come together.”

    As for industrial processes, Bilge Yildiz, a professor of nuclear science and engineering and materials science and engineering, said that “the synthesis of industrial chemicals and materials constitutes about 33 percent of global CO2 emissions at present, and so our goal is to decarbonize this difficult sector.” About half of all these industrial emissions come from the production of just four materials: steel, cement, ammonia, and ethylene, so there is a major focus of research on ways to reduce their emissions.

    Most of the processes to make these materials have changed little for more than a century, she said, and they are mostly heat-based processes that involve burning a lot of fossil fuel. But the heat can instead be provided from renewable electricity, which can also be used to drive electrochemical reactions in some cases as a substitute for the thermal reactions. Already, there are processes for making cement and steel that produce only about half the present carbon dioxide (CO2) emissions.

    The production of ammonia, which is widely used in fertilizer and other bulk chemicals, accounts for more greenhouse gas emissions than any other industrial source. The present thermochemical process could be replaced by an electrochemical process, she said. Similarly, the production of ethylene, as a feedstock for plastics and other materials, is the second-highest emissions producer, with three tons of carbon dioxide released for every ton of ethylene produced. Again, an electrochemical alternative method exists, but needs to be improved to be cost competitive.

    As the world moves toward electrification of industrial processes to eliminate fossil fuels, the need for emissions-free sources of electricity will continue to increase. One very promising potential addition to the range of carbon-free generation sources is fusion, a field in which MIT is a leader in developing a particularly promising technology that takes advantage of the unique properties of high-temperature superconducting (HTS) materials.

    Dennis Whyte, the director of MIT’s Plasma Science and Fusion Center, pointed out that despite global efforts to reduce CO2 emissions, “we use exactly the same percentage of carbon-based products to generate energy as 10 years ago, or 20 years ago.” To make a real difference in global emissions, “we need to make really massive amounts of carbon-free energy.”

    Fusion, the process that powers the sun, is a particularly promising pathway, because the fuel, derived from water, is virtually inexhaustible. By using recently developed HTS material to generate the powerful magnetic fields needed to produce a sustained fusion reaction, the MIT-led project, which led to a spinoff company called Commonwealth Fusion Systems, was able to radically reduce the required size of a fusion reactor, Whyte explained. Using this approach, the company, in collaboration with MIT, expects to have a fusion system that produces net energy by the middle of this decade, and be ready to build a commercial plant to produce power for the grid early in the next. Meanwhile, at least 25 other private companies are also attempting to commercialize fusion technology. “I think we can take some credit for helping to spawn what is essentially now a new industry in the United States,” Whyte said.

    Fusion offers the potential, along with existing solar and wind technologies, to provide the emissions-free power the world needs, Whyte says, but that’s only half the problem, the other part being how to get that power to where it’s needed, when it’s needed. “How do we adapt these new energy sources to be as compatible as possible with everything that we have already in terms of energy delivery?”

    Part of the way to find answers to that, he suggested, is more collaborative work on these issues that cut across disciplines, as well as more of the kinds of cross-cutting conversations and interactions that took place in this panel discussion. More

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    A clean alternative to one of the world’s most common ingredients

    Never underestimate the power of a time crunch.

    In 2016, MIT classmates David Heller ’18, Shara Ticku, and Harry McNamara PhD ’19 were less than two weeks away from the deadline to present a final business plan as part of their class MAS.883 (Revolutionary Ventures: How to Invent and Deploy Transformative Technologies). The students had connected over a shared passion for using biology to solve climate challenges, but their first few ideas didn’t pan out, so they went back to the drawing board.

    In a brainstorming session, Ticku began to reminisce about a trip to Singapore she’d taken where the burning of forests had cast a dark haze over the city. The story sparked a memory from halfway across the world in Costa Rica, where McNamara had traveled and noticed endless rows of palm plantations, which are used to harvest palm oil.

    “Besides Shara’s experience in Singapore and Harry’s in Costa Rica, palm was a material none of us had seriously thought about,” Heller recalls. “That conversation made us realize it was a big, big industry, and there’s major issues to the way that palm is produced.”

    The classmates decided to try using synthetic biology to create a sustainable alternative to palm oil. The idea was the beginning of C16 Biosciences. Today C16 is fulfilling that mission at scale with a palm oil alternative it harvests from oil-producing yeast, which ferment sugars in a process similar to brewing beer.

    The company’s product, which it sells to personal care brands and directly to consumers, holds enormous potential to improve the sustainability of the personal care and food industries because, as it turns out, the classmates had stumbled onto a massive problem.

    Palm oil is the most popular vegetable oil in the world. It’s used in everything from soaps and cosmetics to sauces, rolls, and crackers. But palm oil can only be harvested from palm trees near the equator, so producers often burn down tropical rainforests and swamps in those regions to make way for plantations, decimating wildlife habitats and producing a staggering amount of greenhouse gas emissions. One recent study found palm expansion in Southeast Asia could account for 0.75 percent of the world’s total greenhouse gas emissions. That’s not even including the palm expansion happening across west Africa and South America. Among familiar creatures threatened by palm oil deforestation are orangutans, all three species of which are now listed as “critically endangered” — the most urgent status on the IUCN Red List of Threatened Species, a global endangered species list.

    “To respond to increasing demand over the last few decades, large palm producers usually inappropriately seize land,” Heller explains. “They’ll literally slash and burn tropical rainforests to the ground, drive out indigenous people, they’ll kill or drive out local wildlife, and they’ll replace everything with hectares and hectares of palm oil plantations. That land conversion process has been emitting something like a gigaton of CO2 per year, just for the expansion of palm oil.”

    From milliliters to metric tons

    Heller took Revolutionary Ventures his junior year as one of the few undergraduates in the Media Lab-based class, which is also open to students from nearby colleges. On one of the first days, students were asked to stand in front of the class and explain their passions, or “what makes them tick,” as Heller recalls. He focused on climate tech.

    McNamara, who was a PhD candidate in the Harvard-MIT Program in Health Sciences and Technology at the time, talked about his interest in applying new technology to global challenges in biotech and biophysics. Ticku, who was attending Harvard Business School, discussed her experience working in fertility health and her passion for global health initiatives. The three decided to team up.

    “The core group is very, very passionate about using biology to solve major climate problems,” says Heller, who majored in biological engineering while at MIT.

    After a successful final presentation in the class, the founders received a small amount of funding by participating in the MIT $100K Pitch Competition and from the MIT Sandbox Innovation Fund.

    “MIT Sandbox was one of our first bits of financial support,” Heller says. “We also received great mentorship. We learned from other startups at MIT and made connections with professors whom we learned a lot from.”

    By the time Heller graduated in 2018, the team had experimented with different yeast strains and produced a few milliliters of oil. The process has gradually been optimized and scaled up from there. Today C16 is producing metric tons of oil in 50,000-liter tanks and has launched a consumer cosmetic brand called Palmless.

    Heller says C16 started its own brand as a way to spread the word about the harms associated with palm oil and to show larger companies it was ready to be a partner.

    “The oil palm tree is amazing in terms of the yields it generates, but the location needed for the crop is in conflict with what’s essential in our ecosystem: tropical rainforests,” Heller says. “There’s a lot of excitement when it comes to microbial palm alternatives. A lot of brands have been under pressure from consumers and even governments who are feeling the urgency around climate and are feeling the urgency from consumers to make changes to get away from an oil ingredient that is incredibly destructive.”

    Scaling with biology

    C16’s first offering, which it calls Torula Oil, is a premium product compared to traditional palm oil, but Heller notes the cost of palm oil today is deflated because companies don’t factor in its costs to the planet and society. He also notes that C16 has a number of advantages in its quest to upend the $60 billion palm oil industry: It’s far easier to improve the productivity of C16’s precision fermentation process than it is to improve agricultural processes. C16 also expects its costs to plummet as it continues to grow.

    “What’s exciting for us is we have these economies of scale,” Heller says. “We have the opportunity to expand vertically, in large stainless steel tanks, as opposed to horizontally on land, so we can drive down our cost curve by increasing the size of the infrastructure and improving the optimization of our strain. The timelines for improvement in a precision fermentation process are a fraction of the time it takes in an agricultural context.”

    Heller says C16 is currently focused on partnering with large personal care brands and expects to announce some important deals in coming months. Further down the line, C16 also hopes to use its product to replace the palm oil in food products, although additional regulations mean that dream is still a few years away.

    With all of its efforts, C16 tries to shine a light on the problems associated with the palm industry, which the company feels are underappreciated despite palm oil’s ubiquitous presence in our society.

    “We need to find a way to reduce our reliance on deforestation products,” Heller says. “We do a lot of work to help educate people on the palm oil industry. Just because something has palm oil in it doesn’t mean you should stop using it, but you should understand what that means for the world.” More

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    Arina Khotimsky ’23 awarded 2023 Michel David-Weill Scholarship

    Arina Khotimsky ’23 was selected for the 2023 Michel David-Weill scholarship, awarded each year to one student from the United States in a master’s program at Sciences Po in France who exemplifies the core values embodied by its namesake: excellence, leadership, multiculturalism, and high achievement. This fall Khotimsky will enter the master’s program in international energy, which is part of Sciences Po’s Paris School of International Affairs. The program aims to provide a holistic understanding of energy issues, across disciplines and across all energy sources.

    Khotimsky graduated this year from MIT with a major in materials science and engineering, and minors in energy studies and in French.

    Asked what drew her to her major, Khotimsky talked about her love of the outdoors. Seeing effects of climate change on the world around made her made her want to explore solutions. “I settled on material science and engineering because there’s so many different applications: whether it be solar power, developing different battery materials and chemistries, or some other technology. Getting that technical background at MIT can help me understand how we can implement solutions around the world, with diverse cultures in mind.”

    One of Khotimsky’s material sciences professors, Polina Anikeeva, observes that “Arina possesses the spirit of creativity, optimism, and unparalleled work ethic — all necessary ingredients to solve energy and climate challenges of our century.”

    Khotimsky is well aware of the big stakes in discussions around energy policy. She explains, “We have to cooperate internationally to make a dent in carbon emissions. The United States is historically the biggest CO2 emitter and has a large role to play to transition to a more sustainable future.”

    Her interest in studying climate change solutions on a world scale also converged with her interest in studying other languages and cultures. Her main language studies at MIT have been in French, although she also speaks Russian and beginner Chinese.

    Due to her achievement in MIT French classes, Khotimsky was one of nine students selected for a two-week cultural immersion program in Paris last June, led by MIT Professor Bruno Perreau. Perreau also had her in class last fall, and spoke about the energy and commitment she brought to class, describing her as “one of my very best students since I started to teach 22 years ago.” Khotimsky is excited to be living in France for her master’s program and putting her French skills to work.

    Khotimsky’s impressive undergraduate career has also included being co-president of the MIT Energy and Climate Club, and participating in the MIT delegation to 2022 Conference of the Parties summit (COP27) of the United Nations in Egypt last November. She also participated in the NEET Decarbonizing Ulaanbaatar project, traveling to Mongolia in Independent Activities Period 2023 with a group of students and instructors to work on clean heating technologies for traditional ger homes.

    In addition to her academic work and other extracurricular activities, Khotimsky was also a member of the MIT women’s rowing team. She walked onto the team as a first-year student, making it into the Varsity 8 boat for her senior season. Holly Metcalf, MIT women’s varsity openweight rowing coach, explains, “Being on the rowing team has in many ways become a metaphor for what Arina has come to study … She realized that rowing is about so much more than physics — it is about who one must become as an individual to contribute to the sum of mental and physical strength of the entire team.” Khotimsky was recognized on May 22 by the Patriot League, who named her the 2023 Patriot League Women’s Rowing Scholar-Athlete of the Year.

    Looking ahead, Khotimsky envisions her future involving international energy negotiations or policy. “The master’s degree I’m pursuing in international relations will help me develop skills to communicate with stakeholders from around the world and figure out how to implement solutions globally.” More