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    Pivot Bio is using microbial nitrogen to make agriculture more sustainable

    The Haber-Bosch process, which converts atmospheric nitrogen to make ammonia fertilizer, revolutionized agriculture and helped feed the world’s growing population, but it also created huge environmental problems. It is one of the most energy-intensive chemical processes in the world, responsible for 1-2 percent of global energy consumption. It also releases nitrous oxide, a potent greenhouse gas that harms the ozone layer. Excess nitrogen also routinely runs off farms into waterways, harming marine life and polluting groundwater.In place of synthetic fertilizer, Pivot Bio has engineered nitrogen-producing microbes to make farming more sustainable. The company, which was co-founded by Professor Chris Voigt, Karsten Temme, and Alvin Tamsir, has engineered its microbes to grow on plant roots, where they feed on the root’s sugars and precisely deliver nitrogen in return.Pivot’s microbial colonies grow with the plant and produce more nitrogen at exactly the time the plant needs it, minimizing nitrogen runoff.“The way we have delivered nutrients to support plant growth historically is fertilizer, but that’s an inefficient way to get all the nutrients you need,” says Temme, Pivot’s chief innovation officer. “We have the ability now to help farmers be more efficient and productive with microbes.”Farmers can replace up to 40 pounds per acre of traditional nitrogen with Pivot’s product, which amounts to about a quarter of the total nitrogen needed for a crop like corn.Pivot’s products are already being used to grow corn, wheat, barley, oats, and other grains across millions of acres of American farmland, eliminating hundreds of thousands of tons of CO2 equivalent in the process. The company’s impact is even more striking given its unlikely origins, which trace back to one of the most challenging times of Voigt’s career.A Pivot from despairThe beginning of every faculty member’s career can be a sink-or-swim moment, and by Voigt’s own account, he was drowning. As a freshly minted assistant professor at the University of California at San Francisco, Voigt was struggling to stand up his lab, attract funding, and get experiments started.Around 2008, Voigt joined a research group out of the University of California at Berkeley that was writing a grant proposal focused on photovoltaic materials. His initial role was minor, but a senior researcher pulled out of the group a week before the proposal had to be submitted, so Voigt stepped up.“I said ‘I’ll finish this section in a week,’” Voigt recalls. “It was my big chance.”For the proposal, Voigt detailed an ambitious plan to rearrange the genetics of biologic photosynthetic systems to make them more efficient. He barely submitted it in time.A few months went by, then the proposal reviews finally came back. Voigt hurried to the meeting with some of the most senior researchers at UC Berkeley to discuss the responses.“My part of the proposal got completely slammed,” Voigt says. “There were something like 15 reviews on it — they were longer than the actual grant — and it’s just one after another tearing into my proposal. All the most famous people are in this meeting, future energy secretaries, future leaders of the university, and it was totally embarrassing. After that meeting, I was considering leaving academia.”A few discouraging months later, Voigt got a call from Paul Ludden, the dean of the School of Science at UC Berkeley. He wanted to talk.“As I walk into Paul’s office, he’s reading my proposal,” Voigt recalls. “He sits me down and says, ‘Everybody’s telling me how terrible this is.’ I’m thinking, ‘Oh my God.’ But then he says, ‘I think there’s something here. Your idea is good, you just picked the wrong system.’”Ludden went on to explain to Voigt that he should apply his gene-swapping idea to nitrogen fixation. He even offered to send Voigt a postdoc from his lab, Dehua Zhao, to help. Voigt paired Zhao with Temme, and sure enough, the resulting 2011 paper of their work was well-received by the nitrogen fixation community.“Nitrogen fixation has been a holy grail for scientists, agronomists, and farmers for almost a century, ever since somebody discovered the first microbe that can fix nitrogen for legumes like soybeans,” Temme says. “Everybody always said that someday we’ll be able to do this for the cereal crops. The excitement with Pivot was this is the first time that technology became accessible.”Voigt had moved to MIT in 2010. When the paper came out, he founded Pivot Bio with Temme and another Berkeley researcher, Alvin Tamsir. Since then, Voigt, who is the Daniel I.C. Wang Professor at MIT and the head of the Department of Biological Engineering, has continued collaborating with Pivot on things like increasing nitrogen production, making strains more stable, and making them inducible to different signals from the plant. Pivot has licensed technology from MIT, and the research has also received support from MIT’s Abdul Latif Jameel Water and Food Systems Lab (J-WAFS).Pivot’s first goals were to gain regulatory approval and prove themselves in the marketplace. To gain approval in the U.S., Pivot’s team focused on using DNA from within the same organism rather than bringing in totally new DNA, which simplified the approval process. It also partnered with independent corn seed dealers to get its product to farms. Early deployments occurred in 2019.Farmers apply Pivot’s product at planting, either as a liquid that gets sprayed on the soil or as a dry powder that is rehydrated and applied to the seeds as a coating. The microbes live on the surface of the growing root system, eating plant sugars and releasing nitrogen throughout the plant’s life cycle.“Today, our microbes colonize just a fraction of the total sugars provided by the plant,” Temme explains. “They’re also sharing ammonia with the plant, and all of those things are just a portion of what’s possible technically. Our team is always trying to figure out how to make those microbes more efficient at getting the energy they need to grow or at fixing nitrogen and sharing it with the crop.”In 2023, Pivot started the N-Ovator program to connect companies with growers who practice sustainable farming using Pivot’s microbial nitrogen. Through the program, companies buy nitrogen credits and farmers can get paid by verifying their practices. The program was named one of the Inventions of the Year by Time Magazine last year and has paid out millions of dollars to farmers to date.Microbial nitrogen and beyondPivot is currently selling to farmers across the U.S. and working with smallholder farmers in Kenya. It’s also hoping to gain approval for its microbial solution in Brazil and Canada, which it hopes will be its next markets.”How do we get the economics to make sense for everybody — the farmers, our partners, and the company?” Temme says of Pivot’s mission. “Because this truly can be a deflationary technology that upends the very expensive traditional way of making fertilizer.”Pivot’s team is also extending the product to cotton, and Temme says microbes can be a nitrogen source for any type of plant on the planet. Further down the line, the company believes it can help farmers with other nutrients essential to help their crops grow.“Now that we’ve established our technology, how can Pivot help farmers overcome all the other limitations they face with crop nutrients to maximize yields?” Temme asks. “That really starts to change the way a farmer thinks about managing the entire acre from a price, productivity, and sustainability perspective.” More

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    Creating smart buildings with privacy-first sensors

    Gaining a better understanding of how people move through the spaces where they live and work could make those spaces safer and more sustainable. But no one wants cameras watching them 24/7.Two former Media Lab researchers think they have a solution. Their company, Butlr, offers places like skilled nursing facilities, offices, and senior living communities a way to understand how people are using buildings without compromising privacy. Butlr uses low-resolution thermal sensors and an analytics platform to help detect falls in elderly populations, save energy, and optimize spaces for work.“We have this vision of using the right technology to understand people’s movements and behaviors in space,” says Jiani Zeng SM ’20, who co-founded Butlr with former Media Lab research affiliate Honghao Deng. “So many resources today go toward cameras and AI that take away people’s privacy. We believe we can make our environments safer, healthier, and more sustainable without violating privacy.”To date, the company has sold more than 20,000 of its privacy-preserving sensors to senior living and skilled nursing facilities as well as businesses with large building footprints, including Verizon, Netflix, and Microsoft. In the future, Butlr hopes to enable more dynamic spaces that can understand and respond to the ways people use them.“Space should be like a digital user interface: It should be multi-use and responsive to your needs,” Deng says. “If the office has a big room with people working individually, it should automatically separate into smaller rooms, or lights and temperature should be adjusted to save energy.”Building intelligence, with privacyAs an undergraduate at Tianjin University in China, Deng joined the Media Lab’s City Science Group as a visiting student in 2016. He went on to complete his master’s at Harvard University, but he returned to the Media Lab as a research affiliate and led projects around what he calls responsive architecture: spaces that can understand their users’ needs through non-camera sensors.“My vision of the future of building environments emerged from the Media Lab,” Deng says. “The real world is the largest user interface around us — it’s not the screens. We all live in a three-dimensional world and yet, unlike the digital world, this user interface doesn’t yet understand our needs, let alone the critical situations when someone falls in a room. That could be life-saving.”Zeng came to MIT as a master’s student in the Integrated Design and Management program, which was run jointly out of the MIT Sloan School of Management and the School of Engineering. She also worked as a research assistant at the Media Lab and the Computer Science and Artificial Intelligence Lab (CSAIL).The pair met during a hackathon at the Media Lab and continued collaborating on various projects. During that time, they worked with MIT’s Venture Mentoring Service (VMS) and the MIT I-Corps Program. When they graduated in 2019, they decided to start a company based on the idea of creating smart buildings with privacy-preserving sensors. Crucial early funding came from the Media Lab-affiliated E14 Fund.“I tell every single MIT founder they should have the E14 Fund in their cap table,” Deng says. “They understand what it takes to go from an MIT student to a founder, and to transition from the ‘scientist brain’ to the ‘inventor brain.’ We wouldn’t be where we are today without MIT.”Ray Stata ’57, SM ’58, the founder of Analog Devices, is also an investor in Butlr and serves as Butlr’s board director.“We would love to give back to the MIT community once we become successful entrepreneurs like Ray, whose advice and mentoring has been invaluable,” Deng says.After launching, the founders had to find the right early customers for their real-time sensors, which can discern rough body shapes but no personally identifiable information. They interviewed hundreds of people before starting with owners of office spaces.“People have zero baseline data on what’s happening in their workplace,” Deng says. “That’s especially true since the Covid-19 pandemic made people hybrid, which has opened huge opportunities to cut the energy use of large office spaces. Sometimes, the only people in these buildings are the receptionist and the cleaner.”Butlr’s multiyear, battery-powered sensors can track daily occupancy in each room and give other insights into space utilization that can be used to reduce energy use. For companies with a lot of office space, the opportunities are immense. One Butlr customer has 40 building leases. Deng says optimizing the HVAC controls based on usage could amount to millions of dollars saved.“We can be like the Google Analytics for these spaces without any concerns in terms of privacy,” Deng says.The founders also knew the problem went well beyond office spaces.“In skilled nursing facilities, instead of office spaces it’s individual rooms, all with people who may need the nurse’s help,” Deng says. “But the nurses have no visibility into what’s happening unless they physically enter the room.”Acute care environments and senior living facilities are another key market for Butlr. The company’s platform can detect falls and instances when someone isn’t getting out of bed to alert staff. The system integrates with nurse calling systems to alert staff when something is wrong.The “nerve cells” of the buildingButlr is continuing to develop analytics that give important insights into spaces. For instance, today the platform can use information around movement in elderly populations to help detect problems like urinary tract infections. Butlr also recently started a collaboration with Harvard Medical School’s Beth Israel Deaconess Medical Center and the University of Massachusetts at Amherst’s Artificial Intelligence and Technology Center for Connected Care in Aging and Alzheimer’s Disease. Through the project, Butlr will try to detect changes in movement that could indicate declining cognitive or physical abilities. Those insights could be used to provide aging patients with more supervision.“In the near term we are preventing falls, but the vision is when you look up in any buildings or homes, you’ll see Butlr,” Deng says. “This could allow older adults to age in place with dignity and privacy.”More broadly, Butlr’s founders see their work as an important way to shape the future of AI technology, which is expected to be a growing part of everyone’s lives.“We’re the nerve cells in the building, not the eyes,” Deng says. “That’s the future of AI we believe in: AI that can transform regular rooms into spaces that understand people and can use that understanding to do everything from making efficiency improvements to saving lives in senior care communities. That’s the right way to use this powerful technology.” More

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    Cleaning up critical minerals and materials production, using microwave plasma

    The push to bring manufacturing back to the U.S. is running up against an unfortunate truth: The processes for making many critical materials today create toxic byproducts and other environmental hazards. That’s true for commonly used industrial metals like nickel and titanium, as well as specialty minerals, materials, and coatings that go into batteries, advanced electronics, and defense applications.Now 6K, founded by former MIT research scientist Kamal Hadidi, is using a new production process to bring critical materials production back to America without the toxic byproducts.The company is actively scaling its microwave plasma technology, which it calls UniMelt, to transform the way critical minerals are processed, creating new domestic supply chains in the process. UniMelt uses beams of tightly controlled thermal plasma to melt or vaporize precursor materials into particles with precise sizes and crystalline phases.The technology converts metals, such as titanium, nickel, and refractory alloys, into particles optimized for additive manufacturing for a range of industrial applications. It is also being used to create battery materials for electric vehicles, grid infrastructure, and data centers.“The markets and critical materials we are focused on are important for not just economic reasons but also U.S. national security, because the bulk of these materials are manufactured today in nonfriendly countries,” 6K CEO Saurabh Ullal says. “Now, the [U.S. government] and our growing customer base can leverage this technology invented at MIT to make the U.S. less dependent on these nonfriendly countries, ensuring supply chain independence now and in the future.”Named after the 6,000-degree temperature of its plasma, 6K is currently selling its high-performance metal powders to parts manufacturers as well as defense, automotive, medical, and oil and gas companies for use in applications from engine components and medical implants to rockets. To scale its battery materials business, 6K is also building a 100,000-square-foot production facility in Jackson, Tennessee, which will begin construction later this year.A weekend projectBetween 1994 and 2007, Hadidi worked at the Plasma Science and Fusion Center (PFSC), where he developed plasma technologies for a range of applications, including hydrogen production, fuel reforming, and detecting environmental toxins. His first company was founded in 2000 out of the PFSC to detect mercury in coal-fired power plants’ smokestacks.“I loved working at MIT,” Hadidi says. “It’s an amazing place that really challenges you. Just being there is so stimulating because everyone’s trying to come up with new solutions and connect dots between different fields.”Hadidi also began using high-frequency microwave plasmas to create nanomaterials for use in optical applications. He wasn’t a materials expert, so he collaborated with Professor Eric Jordan, a materials synthesis expert from the University of Connecticut, and the researchers started working on nights and weekends in the PSFC to develop the idea further, eventually patenting the technology.Hadidi officially founded the company as Amastan in 2007, exploring the use of his microwave plasma technology, later named UniMelt for “uniform melt state process,” to make a host of different materials as part of a government grant he and Jordan received.The researchers soon realized the microwave plasma technology had several advantages over traditional production techniques for certain materials. For one, it could eliminate several high-energy steps of conventional processes, reducing production times from days to hours in some cases. For batteries and certain critical minerals, the process also works with recycled feedstocks. Amastan was renamed 6K in 2019.Early on, Hadidi produced metal powders used in additive manufacturing through a process called spheroidization, which results in dense, spherical powders that flow well and make high-performance 3D-printed parts.Following another grant, Hadidi explored methods for producing a type of battery cathode made from lithium, nickel, manganese, and cobalt (NMC). The standard process for making NMCs involved chemical synthesis, precipitation, heat treatment, and a lot of water. 6K is able to reduce many of those steps, speeding up production and lowering costs while also being more sustainable.“Our technology completely eliminates toxic waste and recycles all of the byproducts back through the process to utilize everything, including water,” Ullal says.Scaling domestic productionToday, 6K’s additive manufacturing arm operates out of a factory in Pennsylvania. The company’s critical minerals processing, refining, and recycling systems can produce about 400 tons of material per year and can be used to make more than a dozen types of metal powders. The company also has 33,000-square-foot battery center in North Andover, Massachusetts, where it produces battery cathode materials for its energy storage and mobility customers.The Tennessee facility will be used to produce battery cathode materials and represents a massive step up in throughput. The company says it will be able to produce 13,000 tons of material annually when construction is complete next year.“I’m happy if what I started brings something positive to society, and I’m extremely thankful to all the people that helped me,” says Hadidi, who left the company in 2019. “I’m an entrepreneur at heart. I like to make things. But that doesn’t mean I always succeed. It’s personally very satisfying to see this make an impact.”The 6K team says its technology can also create a variety of specialty ceramics, advanced coatings, and nanoengineered materials. They say it may also be used to eliminate PFAS, or “forever chemicals,” though that work is at an early stage.The company recently received a grant to demonstrate a process for recycling critical materials from military depots to produce aerospace and defense products, creating a new value stream for these materials that would otherwise deteriorate or go to landfill. That work is consistent with the company’s motto, “We take nothing from the ground and put nothing into the ground.”The company’s additive division recently received a $23.4 Defense Production Act grant “that will enable us to double processing capacity in the next three years,” Ullal says. “The next step is to scale battery materials production to the tens of thousands of tons per year. At this point, it’s a scale-up of known processes, and we just need to execute. The idea of creating a circular economy is near and dear to us because that’s how we’ve built this company and that’s how we generate value: addressing our U.S. national security concerns and protecting the planet as well.” More

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    MIT spinout Gradiant reduces companies’ water use and waste by billions of gallons each day

    When it comes to water use, most of us think of the water we drink. But industrial uses for things like manufacturing account for billions of gallons of water each day. For instance, making a single iPhone, by one estimate, requires more than 3,000 gallons.Gradiant is working to reduce the world’s industrial water footprint. Founded by a team from MIT, Gradiant offers water recycling, treatment, and purification solutions to some of the largest companies on Earth, including Coca Cola, Tesla, and the Taiwan Semiconductor Manufacturing Company. By serving as an end-to-end water company, Gradiant says it helps companies reuse 2 billion gallons of water each day and saves another 2 billion gallons of fresh water from being withdrawn.The company’s mission is to preserve water for generations to come in the face of rising global demand.“We work on both ends of the water spectrum,” Gradiant co-founder and CEO Anurag Bajpayee SM ’08, PhD ’12 says. “We work with ultracontaminated water, and we can also provide ultrapure water for use in areas like chip fabrication. Our specialty is in the extreme water challenges that can’t be solved with traditional technologies.”For each customer, Gradiant builds tailored water treatment solutions that combine chemical treatments with membrane filtration and biological process technologies, leveraging a portfolio of patents to drastically cut water usage and waste.“Before Gradiant, 40 million liters of water would be used in the chip-making process. It would all be contaminated and treated, and maybe 30 percent would be reused,” explains Gradiant co-founder and COO Prakash Govindan PhD ’12. “We have the technology to recycle, in some cases, 99 percent of the water. Now, instead of consuming 40 million liters, chipmakers only need to consume 400,000 liters, which is a huge shift in the water footprint of that industry. And this is not just with semiconductors. We’ve done this in food and beverage, we’ve done this in renewable energy, we’ve done this in pharmaceutical drug production, and several other areas.”Learning the value of waterGovindan grew up in a part of India that experienced a years-long drought beginning when he was 10. Without tap water, one of Govindan’s chores was to haul water up the stairs of his apartment complex each time a truck delivered it.“However much water my brother and I could carry was how much we had for the week,” Govindan recalls. “I learned the value of water the hard way.”Govindan attended the Indian Institute of Technology as an undergraduate, and when he came to MIT for his PhD, he sought out the groups working on water challenges. He began working on a water treatment method called carrier gas extraction for his PhD under Gradiant co-founder and MIT Professor John Lienhard.Bajpayee also worked on water treatment methods at MIT, and after brief stints as postdocs at MIT, he and Govindan licensed their work and founded Gradiant.Carrier gas extraction became Gradiant’s first proprietary technology when the company launched in 2013. The founders began by treating wastewater created by oil and gas wells, landing their first partner in a Texas company. But Gradiant gradually expanded to solving water challenges in power generation, mining, textiles, and refineries. Then the founders noticed opportunities in industries like electronics, semiconductors, food and beverage, and pharmaceuticals. Today, oil and gas wastewater treatment makes up a small percentage of Gradiant’s work.As the company expanded, it added technologies to its portfolio, patenting new water treatment methods around reverse osmosis, selective contaminant extraction, and free radical oxidation. Gradiant has also created a digital system that uses AI to measure, predict, and control water treatment facilities.“The advantage Gradiant has over every other water company is that R&D is in our DNA,” Govindan says, noting Gradiant has a world-class research lab at its headquarters in Boston. “At MIT, we learned how to do cutting-edge technology development, and we never let go of that.”The founders compare their suite of technologies to LEGO bricks they can mix and match depending on a customer’s water needs. Gradiant has built more than 2,500 of these end-to-end systems for customers around the world.“Our customers aren’t water companies; they are industrial clients like semiconductor manufacturers, drug companies, and food and beverage companies,” Bajpayee says. “They aren’t about to start operating a water treatment plant. They look at us as their water partner who can take care of the whole water problem.”Continuing innovationThe founders say Gradiant has been roughly doubling its revenue each year over the last five years, and it’s continuing to add technologies to its platform. For instance, Gradiant recently developed a critical minerals recovery solution to extract materials like lithium and nickel from customers’ wastewater, which could expand access to critical materials essential to the production of batteries and other products.“If we can extract lithium from brine water in an environmentally and economically feasible way, the U.S. can meet all of its lithium needs from within the U.S.,” Bajpayee says. “What’s preventing large-scale extraction of lithium from brine is technology, and we believe what we have now deployed will open the floodgates for direct lithium extraction and completely revolutionized the industry.”The company has also validated a method for eliminating PFAS — so-called toxic “forever chemicals” — in a pilot project with a leading U.S. semiconductor manufacturer. In the near future, it hopes to bring that solution to municipal water treatment plants to protect cities.At the heart of Gradiant’s innovation is the founders’ belief that industrial activity doesn’t have to deplete one of the world’s most vital resources.“Ever since the industrial revolution, we’ve been taking from nature,” Bajpayee says. “By treating and recycling water, by reducing water consumption and making industry highly water efficient, we have this unique opportunity to turn the clock back and give nature water back. If that’s your driver, you can’t choose not to innovate.” More

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    MIT Climate and Energy Ventures class spins out entrepreneurs — and successful companies

    In 2014, a team of MIT students in course 15.366 (Climate and Energy Ventures) developed a plan to commercialize MIT research on how to move information between chips with light instead of electricity, reducing energy usage.After completing the class, which challenges students to identify early customers and pitch their business plan to investors, the team went on to win both grand prizes at the MIT Clean Energy Prize. Today the company, Ayar Labs, has raised a total of $370 million from a group including chip leaders AMD, Intel, and NVIDIA, to scale the manufacturing of its optical chip interconnects.Ayar Labs is one of many companies whose roots can be traced back to 15.366. In fact, more than 150 companies have been founded by alumni of the class since its founding in 2007.In the class, student teams select a technology or idea and determine the best path for its commercialization. The semester-long project, which is accompanied by lectures and mentoring, equips students with real-world experience in launching a business.“The goal is to educate entrepreneurs on how to start companies in the climate and energy space,” says Senior Lecturer Tod Hynes, who co-founded the course and has been teaching since 2008. “We do that through hands-on experience. We require students to engage with customers, talk to potential suppliers, partners, investors, and to practice their pitches to learn from that feedback.”The class attracts hundreds of student applications each year. As one of the catalysts for MIT spinoffs, it is also one reason a 2015 report found that MIT alumni-founded companies had generated roughly $1.9 trillion in annual revenues. If MIT were a country, that figure that would make it the 10th largest economy in the world, according to the report.“’Mens et manus’ (‘mind and hand’) is MIT’s motto, and the hands-on experience we try to provide in this class is hard to beat,” Hynes says. “When you actually go through the process of commercialization in the real world, you learn more and you’re in a better spot. That experiential learning approach really aligns with MIT’s approach.”Simulating a startupThe course was started by Bill Aulet, a professor of the practice at the MIT Sloan School of Management and the managing director of the Martin Trust Center for MIT Entrepreneurship. After serving as an advisor the first year and helping Aulet launch the class, Hynes began teaching the class with Aulet in the fall of 2008. The pair also launched the Climate and Energy Prize around the same time, which continues today and recently received over 150 applications from teams from around the world.A core feature of the class is connecting students in different academic fields. Each year, organizers aim to enroll students with backgrounds in science, engineering, business, and policy.“The class is meant to be accessible to anybody at MIT,” Hynes says, noting the course has also since opened to students from Harvard University. “We’re trying to pull across disciplines.”The class quickly grew in popularity around campus. Over the last few years, the course has had about 150 students apply for 50 spots.“I mentioned Climate and Energy Ventures in my application to MIT,” says Chris Johnson, a second-year graduate student in the Leaders for Global Operations (LGO) Program. “Coming into MIT, I was very interested in sustainability, and energy in particular, and also in startups. I had heard great things about the class, and I waited until my last semester to apply.”The course’s organizers select mostly graduate students, whom they prefer to be in the final year of their program so they can more easily continue working on the venture after the class is finished.“Whether or not students stick with the project from the class, it’s a great experience that will serve them in their careers,” says Jennifer Turliuk, the practice leader for climate and energy artificial intelligence at the Martin Trust Center for Entrepreneurship, who helped teach the class this fall.Hynes describes the course as a venture-building simulation. Before it begins, organizers select up to 30 technologies and ideas that are in the right stage for commercialization. Students can also come into the class with ideas or technologies they want to work on.After a few weeks of introductions and lectures, students form into multidisciplinary teams of about five and begin going through each of the 24 steps of building a startup described in Aulet’s book “Disciplined Entrepreneurship,” which includes things like engaging with potential early customers, quantifying a value proposition, and establishing a business model. Everything builds toward a one-hour final presentation that’s designed to simulate a pitch to investors or government officials.“It’s a lot of work, and because it’s a team-based project, your grade is highly dependent on your team,” Hynes says. “You also get graded by your team; that’s about 10 percent of your grade. We try to encourage people to be proactive and supportive teammates.”Students say the process is fast-paced but rewarding.“It’s definitely demanding,” says Sofie Netteberg, a graduate student who is also in the LGO program at MIT. “Depending on where you’re at with your technology, you can be moving very quickly. That’s the stage that I was in, which I found really engaging. We basically just had a lab technology, and it was like, ‘What do we do next?’ You also get a ton of support from the professors.”From the classroom to the worldThis fall’s final presentations took place at the headquarters of the MIT-affiliated venture firm The Engine in front of an audience of professors, investors, members of foundations supporting entrepreneurship, and more.“We got to hear feedback from people who would be the real next step for the technology if the startup gets up and running,” said Johnson, whose team was commercializing a method for storing energy in concrete. “That was really valuable. We know that these are not only people we might see in the next month or the next funding rounds, but they’re also exactly the type of people that are going to give us the questions we should be thinking about. It was clarifying.”Throughout the semester, students treated the project like a real venture they’d be working on well beyond the length of the class.“No one’s really thinking about this class for the grade; it’s about the learning,” says Netteberg, whose team was encouraged to keep working on their electrolyzer technology designed to more efficiently produce green hydrogen. “We’re not stressed about getting an A. If we want to keep working on this, we want real feedback: What do you think we did well? What do we need to keep working on?”Hynes says several investors expressed interest in supporting the businesses coming out of the class. Moving forward, he hopes students embrace the test-bed environment his team has created for them and try bold new things.“People have been very pragmatic over the years, which is good, but also potentially limiting,” Hynes says. “This is also an opportunity to do something that’s a little further out there — something that has really big potential impact if it comes together. This is the time where students get to experiment, so why not try something big?” More

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    For clean ammonia, MIT engineers propose going underground

    Ammonia is the most widely produced chemical in the world today, used primarily as a source for nitrogen fertilizer. Its production is also a major source of greenhouse gas emissions — the highest in the whole chemical industry.Now, a team of researchers at MIT has developed an innovative way of making ammonia without the usual fossil-fuel-powered chemical plants that require high heat and pressure. Instead, they have found a way to use the Earth itself as a geochemical reactor, producing ammonia underground. The processes uses Earth’s naturally occurring heat and pressure, provided free of charge and free of emissions, as well as the reactivity of minerals already present in the ground.The trick the team devised is to inject water underground, into an area of iron-rich subsurface rock. The water carries with it a source of nitrogen and particles of a metal catalyst, allowing the water to react with the iron to generate clean hydrogen, which in turn reacts with the nitrogen to make ammonia. A second well is then used to pump that ammonia up to the surface.The process, which has been demonstrated in the lab but not yet in a natural setting, is described today in the journal Joule. The paper’s co-authors are MIT professors of materials science and engineering Iwnetim Abate and Ju Li, graduate student Yifan Gao, and five others at MIT.“When I first produced ammonia from rock in the lab, I was so excited,” Gao recalls. “I realized this represented an entirely new and never-reported approach to ammonia synthesis.’”The standard method for making ammonia is called the Haber-Bosch process, which was developed in Germany in the early 20th century to replace natural sources of nitrogen fertilizer such as mined deposits of bat guano, which were becoming depleted. But the Haber-Bosch process is very energy intensive: It requires temperatures of 400 degrees Celsius and pressures of 200 atmospheres, and this means it needs huge installations in order to be efficient. Some areas of the world, such as sub-Saharan Africa and Southeast Asia, have few or no such plants in operation.  As a result, the shortage or extremely high cost of fertilizer in these regions has limited their agricultural production.The Haber-Bosch process “is good. It works,” Abate says. “Without it, we wouldn’t have been able to feed 2 out of the total 8 billion people in the world right now, he says, referring to the portion of the world’s population whose food is grown with ammonia-based fertilizers. But because of the emissions and energy demands, a better process is needed, he says.Burning fuel to generate heat is responsible for about 20 percent of the greenhouse gases emitted from plants using the Haber-Bosch process. Making hydrogen accounts for the remaining 80 percent.  But ammonia, the molecule NH3, is made up only of nitrogen and hydrogen. There’s no carbon in the formula, so where do the carbon emissions come from? The standard way of producing the needed hydrogen is by processing methane gas with steam, breaking down the gas into pure hydrogen, which gets used, and carbon dioxide gas that gets released into the air.Other processes exist for making low- or no-emissions hydrogen, such as by using solar or wind-generated electricity to split water into oxygen and hydrogen, but that process can be expensive. That’s why Abate and his team worked on developing a system to produce what they call geological hydrogen. Some places in the world, including some in Africa, have been found to naturally generate hydrogen underground through chemical reactions between water and iron-rich rocks. These pockets of naturally occurring hydrogen can be mined, just like natural methane reservoirs, but the extent and locations of such deposits are still relatively unexplored.Abate realized this process could be created or enhanced by pumping water, laced with copper and nickel catalyst particles to speed up the process, into the ground in places where such iron-rich rocks were already present. “We can use the Earth as a factory to produce clean flows of hydrogen,” he says.He recalls thinking about the problem of the emissions from hydrogen production for ammonia: “The ‘aha!’ moment for me was thinking, how about we link this process of geological hydrogen production with the process of making Haber-Bosch ammonia?”That would solve the biggest problem of the underground hydrogen production process, which is how to capture and store the gas once it’s produced. Hydrogen is a very tiny molecule — the smallest of them all — and hard to contain. But by implementing the entire Haber-Bosch process underground, the only material that would need to be sent to the surface would be the ammonia itself, which is easy to capture, store, and transport.The only extra ingredient needed to complete the process was the addition of a source of nitrogen, such as nitrate or nitrogen gas, into the water-catalyst mixture being injected into the ground. Then, as the hydrogen gets released from water molecules after interacting with the iron-rich rocks, it can immediately bond with the nitrogen atoms also carried in the water, with the deep underground environment providing the high temperatures and pressures required by the Haber-Bosch process. A second well near the injection well then pumps the ammonia out and into tanks on the surface.“We call this geological ammonia,” Abate says, “because we are using subsurface temperature, pressure, chemistry, and geologically existing rocks to produce ammonia directly.”Whereas transporting hydrogen requires expensive equipment to cool and liquefy it, and virtually no pipelines exist for its transport (except near oil refinery sites), transporting ammonia is easier and cheaper. It’s about one-sixth the cost of transporting hydrogen, and there are already more than 5,000 miles of ammonia pipelines and 10,000 terminals in place in the U.S. alone. What’s more, Abate explains, ammonia, unlike hydrogen, already has a substantial commercial market in place, with production volume projected to grow by two to three times by 2050, as it is used not only for fertilizer but also as feedstock for a wide variety of chemical processes.For example, ammonia can be burned directly in gas turbines, engines, and industrial furnaces, providing a carbon-free alternative to fossil fuels. It is being explored for maritime shipping and aviation as an alternative fuel, and as a possible space propellant.Another upside to geological ammonia is that untreated wastewater, including agricultural runoff, which tends to be rich in nitrogen already, could serve as the water source and be treated in the process. “We can tackle the problem of treating wastewater, while also making something of value out of this waste,” Abate says.Gao adds that this process “involves no direct carbon emissions, presenting a potential pathway to reduce global CO2 emissions by up to 1 percent.” To arrive at this point, he says, the team “overcame numerous challenges and learned from many failed attempts. For example, we tested a wide range of conditions and catalysts before identifying the most effective one.”The project was seed-funded under a flagship project of MIT’s Climate Grand Challenges program, the Center for the Electrification and Decarbonization of Industry. Professor Yet-Ming Chiang, co-director of the center, says “I don’t think there’s been any previous example of deliberately using the Earth as a chemical reactor. That’s one of the key novel points of this approach.”  Chiang emphasizes that even though it is a geological process, it happens very fast, not on geological timescales. “The reaction is fundamentally over in a matter of hours,” he says. “The reaction is so fast that this answers one of the key questions: Do you have to wait for geological times? And the answer is absolutely no.”Professor Elsa Olivetti, a mission director of the newly established Climate Project at MIT, says, “The creative thinking by this team is invaluable to MIT’s ability to have impact at scale. Coupling these exciting results with, for example, advanced understanding of the geology surrounding hydrogen accumulations represent the whole-of-Institute efforts the Climate Project aims to support.”“This is a significant breakthrough for the future of sustainable development,” says Geoffrey Ellis, a geologist at the U.S. Geological Survey, who was not associated with this work. He adds, “While there is clearly more work that needs to be done to validate this at the pilot stage and to get this to the commercial scale, the concept that has been demonstrated is truly transformative.  The approach of engineering a system to optimize the natural process of nitrate reduction by Fe2+ is ingenious and will likely lead to further innovations along these lines.”The initial work on the process has been done in the laboratory, so the next step will be to prove the process using a real underground site. “We think that kind of experiment can be done within the next one to two years,” Abate says. This could open doors to using a similar approach for other chemical production processes, he adds.The team has applied for a patent and aims to work towards bringing the process to market.“Moving forward,” Gao says, “our focus will be on optimizing the process conditions and scaling up tests, with the goal of enabling practical applications for geological ammonia in the near future.”The research team also included Ming Lei, Bachu Sravan Kumar, Hugh Smith, Seok Hee Han, and Lokesh Sangabattula, all at MIT. Additional funding was provided by the National Science Foundation and was carried out, in part, through the use of MIT.nano facilities. More

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    MIT spinout Commonwealth Fusion Systems unveils plans for the world’s first fusion power plant

    America is one step closer to tapping into a new and potentially limitless clean energy source today, with the announcement from MIT spinout Commonwealth Fusion Systems (CFS) that it plans to build the world’s first grid-scale fusion power plant in Chesterfield County, Virginia.The announcement is the latest milestone for the company, which has made groundbreaking progress toward harnessing fusion — the reaction that powers the sun — since its founders first conceived of their approach in an MIT classroom in 2012. CFS is now commercializing a suite of advanced technologies developed in MIT research labs.“This moment exemplifies the power of MIT’s mission, which is to create knowledge that serves the nation and the world, whether via the classroom, the lab, or out in communities,” MIT Vice President for Research Ian Waitz says. “From student coursework 12 years ago to today’s announcement of the siting in Virginia of the world’s first fusion power plant, progress has been amazingly rapid. At the same time, we owe this progress to over 65 years of sustained investment by the U.S. federal government in basic science and energy research.”The new fusion power plant, named ARC, is expected to come online in the early 2030s and generate about 400 megawatts of clean, carbon-free electricity — enough energy to power large industrial sites or about 150,000 homes.The plant will be built at the James River Industrial Park outside of Richmond through a nonfinancial collaboration with Dominion Energy Virginia, which will provide development and technical expertise along with leasing rights for the site. CFS will independently finance, build, own, and operate the power plant.The plant will support Virginia’s economic and clean energy goals by generating what is expected to be billions of dollars in economic development and hundreds of jobs during its construction and long-term operation.More broadly, ARC will position the U.S. to lead the world in harnessing a new form of safe and reliable energy that could prove critical for economic prosperity and national security, including for meeting increasing electricity demands driven by needs like artificial intelligence.“This will be a watershed moment for fusion,” says CFS co-founder Dennis Whyte, the Hitachi America Professor of Engineering at MIT. “It sets the pace in the race toward commercial fusion power plants. The ambition is to build thousands of these power plants and to change the world.”Fusion can generate energy from abundant fuels like hydrogen and lithium isotopes, which can be sourced from seawater, and leave behind no emissions or toxic waste. However, harnessing fusion in a way that produces more power than it takes in has proven difficult because of the high temperatures needed to create and maintain the fusion reaction. Over the course of decades, scientists and engineers have worked to make the dream of fusion power plants a reality.In 2012, teaching the MIT class 22.63 (Principles of Fusion Engineering), Whyte challenged a group of graduate students to design a fusion device that would use a new kind of superconducting magnet to confine the plasma used in the reaction. It turned out the magnets enabled a more compact and economic reactor design. When Whyte reviewed his students’ work, he realized that could mean a new development path for fusion.Since then, a huge amount of capital and expertise has rushed into the once fledgling fusion industry. Today there are dozens of private fusion companies around the world racing to develop the first net-energy fusion power plants, many utilizing the new superconducting magnets. CFS, which Whyte founded with several students from his class, has attracted more than $2 billion in funding.“It all started with that class, where our ideas kept evolving as we challenged the standard assumptions that came with fusion,” Whyte says. “We had this new superconducting technology, so much of the common wisdom was no longer valid. It was a perfect forum for students, who can challenge the status quo.”Since the company’s founding in 2017, it has collaborated with researchers in MIT’s Plasma Science and Fusion Center (PFSC) on a range of initiatives, from validating the underlying plasma physics for the first demonstration machine to breaking records with a new kind of magnet to be used in commercial fusion power plants. Each piece of progress moves the U.S. closer to harnessing a revolutionary new energy source.CFS is currently completing development of its fusion demonstration machine, SPARC, at its headquarters in Devens, Massachusetts. SPARC is expected to produce its first plasma in 2026 and net fusion energy shortly after, demonstrating for the first time a commercially relevant design that will produce more power than it consumes. SPARC will pave the way for ARC, which is expected to deliver power to the grid in the early 2030s.“There’s more challenging engineering and science to be done in this field, and we’re very enthusiastic about the progress that CFS and the researchers on our campus are making on those problems,” Waitz says. “We’re in a ‘hockey stick’ moment in fusion energy, where things are moving incredibly quickly now. On the other hand, we can’t forget about the much longer part of that hockey stick, the sustained support for very complex, fundamental research that underlies great innovations. If we’re going to continue to lead the world in these cutting-edge technologies, continued investment in those areas will be crucial.” More

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    Transforming fusion from a scientific curiosity into a powerful clean energy source

    If you’re looking for hard problems, building a nuclear fusion power plant is a pretty good place to start. Fusion — the process that powers the sun — has proven to be a difficult thing to recreate here on Earth despite decades of research.“There’s something very attractive to me about the magnitude of the fusion challenge,” Hartwig says. “It’s probably true of a lot of people at MIT. I’m driven to work on very hard problems. There’s something intrinsically satisfying about that battle. It’s part of the reason I’ve stayed in this field. We have to cross multiple frontiers of physics and engineering if we’re going to get fusion to work.”The problem got harder when, in Hartwig’s last year in graduate school, the Department of Energy announced plans to terminate funding for the Alcator C-Mod tokamak, a major fusion experiment in MIT’s Plasma Science and Fusion Center that Hartwig needed to do to graduate. Hartwig was able to finish his PhD, and the scare didn’t dissuade him from the field. In fact, he took an associate professor position at MIT in 2017 to keep working on fusion.“It was a pretty bleak time to take a faculty position in fusion energy, but I am a person who loves to find a vacuum,” says Hartwig, who is a newly tenured associate professor at MIT. “I adore a vacuum because there’s enormous opportunity in chaos.”Hartwig did have one very good reason for hope. In 2012, he had taken a class taught by Professor Dennis Whyte that challenged students to design and assess the economics of a nuclear fusion power plant that incorporated a new kind of high-temperature superconducting magnet. Hartwig says the magnets enable fusion reactors to be much smaller, cheaper, and faster.Whyte, Hartwig, and a few other members of the class started working nights and weekends to prove the reactors were feasible. In 2017, the group founded Commonwealth Fusion Systems (CFS) to build the world’s first commercial-scale fusion power plants.Over the next four years, Hartwig led a research project at MIT with CFS that further developed the magnet technology and scaled it to create a 20-Tesla superconducting magnet — a suitable size for a nuclear fusion power plant.The magnet and subsequent tests of its performance represented a turning point for the industry. Commonwealth Fusion Systems has since attracted more than $2 billion in investments to build its first reactors, while the fusion industry overall has exceeded $8 billion in private investment.The old joke in fusion is that the technology is always 30 years away. But fewer people are laughing these days.“The perspective in 2024 looks quite a bit different than it did in 2016, and a huge part of that is tied to the institutional capability of a place like MIT and the willingness of people here to accomplish big things,” Hartwig says.A path to the starsAs a child growing up in St. Louis, Hartwig was interested in sports and playing outside with friends but had little interest in physics. When he went to Boston University as an undergraduate, he studied biomedical engineering simply because his older brother had done it, so he thought he could get a job. But as he was introduced to tools for structural experiments and analysis, he found himself more interested in how the tools worked than what they could do.“That led me to physics, and physics ended up leading me to nuclear science, where I’m basically still doing applied physics,” Hartwig explains.Joining the field late in his undergraduate studies, Hartwig worked hard to get his physics degree on time. After graduation, he was burnt out, so he took two years off and raced his bicycle competitively while working in a bike shop.“There’s so much pressure on people in science and engineering to go straight through,” Hartwig says. “People say if you take time off, you won’t be able to get into graduate school, you won’t be able to get recommendation letters. I always tell my students, ‘It depends on the person.’ Everybody’s different, but it was a great period for me, and it really set me up to enter graduate school with a more mature mindset and to be more focused.”Hartwig returned to academia as a PhD student in MIT’s Department of Nuclear Science and Engineering in 2007. When his thesis advisor, Dennis Whyte, announced a course focused on designing nuclear fusion power plants, it caught Hartwig’s eye. The final projects showed a surprisingly promising path forward for a fusion field that had been stagnant for decades. The rest was history.“We started CFS with the idea that it would partner deeply with MIT and MIT’s Plasma Science and Fusion Center to leverage the infrastructure, expertise, people, and capabilities that we have MIT,” Hartwig says. “We had to start the company with the idea that it would be deeply partnered with MIT in an innovative way that hadn’t really been done before.”Guided by impactHartwig says the Department of Nuclear Science and Engineering, and the Plasma Science and Fusion Center in particular, have seen a huge influx in graduate student applications in recent years.“There’s so much demand, because people are excited again about the possibilities,” Hartwig says. “Instead of having fusion and a machine built in one or two generations, we’ll hopefully be learning how these things work in under a decade.”Hartwig’s research group is still testing CFS’ new magnets, but it is also partnering with other fusion companies in an effort to advance the field more broadly.Overall, when Hartwig looks back at his career, the thing he is most proud of is switching specialties every six years or so, from building equipment for his PhD to conducting fundamental experiments to designing reactors to building magnets.“It’s not that traditional in academia,” Hartwig says. “Where I’ve found success is coming into something new, bringing a naivety but also realism to a new field, and offering a different toolkit, a different approach, or a different idea about what can be done.”Now Hartwig is onto his next act, developing new ways to study materials for use in fusion and fission reactors.“I’m already interested in moving on to the next thing; the next field where I’m not a trained expert,” Hartwig says. “It’s about identifying where there’s stagnation in fusion and in technology, where innovation is not happening where we desperately need it, and bringing new ideas to that.” More