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    Uplifting West African communities, one cashew at a time

    Ever wonder how your favorite snack was sourced? Joshua Reed-Diawuoh thinks more people should.Reed-Diawuoh MBA ’20 is the founder and CEO of GRIA Food Company, which partners with companies that ethically source and process food in West Africa to support local food economies and help communities in the region more broadly.“It’s very difficult for these agribusinesses and producers to start sustainable businesses and build up that value chain in the area,” says Reed-Diawuoh, who started the company as a student in the MIT Sloan School of Management. “We want to support these companies that put in the work to build integrated businesses that are employing people and uplifting communities.”GRIA, which stands for “Grown in Africa,” is currently selling six types of flavored cashews sourced from Benin, Togo, and Burkina Faso. All of the cashews are certified by Fairtrade International, which means in addition to offering sustainable wages, access to financing, and decent working conditions, the companies receive a “Fairtrade Premium” on top of the selling price that allows them to invest in the long-term health of their communities.“That premium is transformational,” Reed-Diawuoh says. “The premium goes to the producer cooperatives, or the farmers working the land, and they can invest that in any way they choose. They can put it back into their business, they can start new community development projects, like building schools or improving wastewater infrastructure, whatever they want.”Cracking the nutReed-Diawuoh’s family is from Ghana, and before coming to MIT Sloan, he worked to support agriculture and food manufacturing for countries in Sub-Saharan Africa, with particular focus on uplifting small-scale farmers. That’s where he learned about difficulties with financing and infrastructure constraints that held many companies back.“I wanted to get my hands dirty and start my own business that contributed to improving agricultural development in West Africa,” Reed-Diawuoh says.He entered MIT Sloan in 2018, taking entrepreneurship classes and exploring several business ideas before deciding to ethically source produce from farmers and sell directly to consumers. He says MIT Sloan’s Sustainability Business Lab offered particularly valuable lessons for how to structure his business.In his second year, Reed-Diawuoh was selected for a fellowship at the Legatum Center, which connected him to other entrepreneurs working in emerging markets around the world.“Legatum was a pivotal milestone for me,” he says. “It provided me with some structure and space to develop this idea. It also gave me an incredible opportunity to take risks and explore different business concepts in a way I couldn’t have done if I was working in industry.”The business model Reed-Diawuoh settled on for GRIA sources product from agribusiness partners in West Africa that adhere to the strictest environmental and labor standards. Reed-Diawuoh decided to start with cashews because they have many manual processing steps — from shelling to peeling and roasting — that are often done after the cashews are shipped out of West Africa, limiting the growth of local food economies and taking wealth out of communities.Each of GRIA’s partners, from the companies harvesting cashews to the processing facilities, works directly with farmer cooperatives and small-scale farmers and is certified by Fairtrade International.“Without proper oversight and regulations, workers oftentimes get exploited, and child labor is a huge problem across the agriculture sector,” Reed-Diawuoh says. “Fairtrade certifications try and take a robust and rigorous approach to auditing all of the businesses and their supply chains, from producers to farmers to processors. They do on-site visits and they audit financial documents. We went through this over the course of a thorough three-month review.”After importing cashew kernels, GRIA flavors and packages them at a production facility in Boston. Reed-Diawuoh started by selling to small independent retailers in Greater Boston before scaling up GRIA’s online sales. He started ramping up production in the beginning of 2023.“Every time we sell our product, if people weren’t already familiar with Fairtrade or ethical sourcing, we provide information on our packaging and all of our collateral,” Reed-Diawuoh says. “We want to spread this message about the importance of ethical sourcing and the importance of building up food manufacturing in West Africa in particular, but also in rising economies throughout the world.”Making ethical sourcing mainstreamGRIA currently imports about a ton of Fairtrade cashews and kernels each quarter, and Reed-Diawuoh hopes to double that number each year for the foreseeable future.“For each pound, we pay premiums for the kernels, and that supports this ecosystem where producers get compensated fairly for their work on the land, and agribusinesses are able to build more robust and profitable business models, because they have an end market for these Fairtrade-certified products.”Reed-Diawuoh is currently trying out different packaging and flavors and is in discussions with partners to expand production capacity and move into Ghana. He’s also exploring corporate collaborations and has provided MIT with product over the past two years for conferences and other events.“We’re experimenting with different growth strategies,” Reed-Diawuoh says. “We’re very much still in startup mode, but really trying to ramp up our sales and production.”As GRIA scales, Reed-Diawuoh hopes it pushes consumers to start asking more of their favorite food brands.“It’s absolutely critical that, if we’re sourcing produce in markets like the U.S. from places like West Africa, we’re hyper-focused on doing it in an ethical manner,” Reed-Diawuoh says. “The overall goal of GRIA is to ensure we are adhering to and promoting strict sourcing standards and being rigorous and thoughtful about the way we import product.” More

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    Translating MIT research into real-world results

    Inventive solutions to some of the world’s most critical problems are being discovered in labs, classrooms, and centers across MIT every day. Many of these solutions move from the lab to the commercial world with the help of over 85 Institute resources that comprise MIT’s robust innovation and entrepreneurship (I&E) ecosystem. The Abdul Latif Jameel Water and Food Systems Lab (J-WAFS) draws on MIT’s wealth of I&E knowledge and experience to help researchers commercialize their breakthrough technologies through the J-WAFS Solutions grant program. By collaborating with I&E programs on campus, J-WAFS prepares MIT researchers for the commercial world, where their novel innovations aim to improve productivity, accessibility, and sustainability of water and food systems, creating economic, environmental, and societal benefits along the way.The J-WAFS Solutions program launched in 2015 with support from Community Jameel, an international organization that advances science and learning for communities to thrive. Since 2015, J-WAFS Solutions has supported 19 projects with one-year grants of up to $150,000, with some projects receiving renewal grants for a second year of support. Solutions projects all address challenges related to water or food. Modeled after the esteemed grant program of MIT’s Deshpande Center for Technological Innovation, and initially administered by Deshpande Center staff, the J-WAFS Solutions program follows a similar approach by supporting projects that have already completed the basic research and proof-of-concept phases. With technologies that are one to three years away from commercialization, grantees work on identifying their potential markets and learn to focus on how their technology can meet the needs of future customers.“Ingenuity thrives at MIT, driving inventions that can be translated into real-world applications for widespread adoption, implantation, and use,” says J-WAFS Director Professor John H. Lienhard V. “But successful commercialization of MIT technology requires engineers to focus on many challenges beyond making the technology work. MIT’s I&E network offers a variety of programs that help researchers develop technology readiness, investigate markets, conduct customer discovery, and initiate product design and development,” Lienhard adds. “With this strong I&E framework, many J-WAFS Solutions teams have established startup companies by the completion of the grant. J-WAFS-supported technologies have had powerful, positive effects on human welfare. Together, the J-WAFS Solutions program and MIT’s I&E ecosystem demonstrate how academic research can evolve into business innovations that make a better world,” Lienhard says.Creating I&E collaborationsIn addition to support for furthering research, J-WAFS Solutions grants allow faculty, students, postdocs, and research staff to learn the fundamentals of how to transform their work into commercial products and companies. As part of the grant requirements, researchers must interact with mentors through MIT Venture Mentoring Service (VMS). VMS connects MIT entrepreneurs with teams of carefully selected professionals who provide free and confidential mentorship, guidance, and other services to help advance ideas into for-profit, for-benefit, or nonprofit ventures. Since 2000, VMS has mentored over 4,600 MIT entrepreneurs across all industries, through a dynamic and accomplished group of nearly 200 mentors who volunteer their time so that others may succeed. The mentors provide impartial and unbiased advice to members of the MIT community, including MIT alumni in the Boston area. J-WAFS Solutions teams have been guided by 21 mentors from numerous companies and nonprofits. Mentors often attend project events and progress meetings throughout the grant period.“Working with VMS has provided me and my organization with a valuable sounding board for a range of topics, big and small,” says Eric Verploegen PhD ’08, former research engineer in MIT’s D-Lab and founder of J-WAFS spinout CoolVeg. Along with professors Leon Glicksman and Daniel Frey, Verploegen received a J-WAFS Solutions grant in 2021 to commercialize cold-storage chambers that use evaporative cooling to help farmers preserve fruits and vegetables in rural off-grid communities. Verploegen started CoolVeg in 2022 to increase access and adoption of open-source, evaporative cooling technologies through collaborations with businesses, research institutions, nongovernmental organizations, and government agencies. “Working as a solo founder at my nonprofit venture, it is always great to have avenues to get feedback on communications approaches, overall strategy, and operational issues that my mentors have experience with,” Verploegen says. Three years after the initial Solutions grant, one of the VMS mentors assigned to the evaporative cooling team still acts as a mentor to Verploegen today.Another Solutions grant requirement is for teams to participate in the Spark program — a free, three-week course that provides an entry point for researchers to explore the potential value of their innovation. Spark is part of the National Science Foundation’s (NSF) Innovation Corps (I-Corps), which is an “immersive, entrepreneurial training program that facilitates the transformation of invention to impact.” In 2018, MIT received an award from the NSF, establishing the New England Regional Innovation Corps Node (NE I-Corps) to deliver I-Corps training to participants across New England. Trainings are open to researchers, engineers, scientists, and others who want to engage in a customer discovery process for their technology. Offered regularly throughout the year, the Spark course helps participants identify markets and explore customer needs in order to understand how their technologies can be positioned competitively in their target markets. They learn to assess barriers to adoption, as well as potential regulatory issues or other challenges to commercialization. NE-I-Corps reports that since its start, over 1,200 researchers from MIT have completed the program and have gone on to launch 175 ventures, raising over $3.3 billion in funding from grants and investors, and creating over 1,800 jobs.Constantinos Katsimpouras, a research scientist in the Department of Chemical Engineering, went through the NE I-Corps Spark program to better understand the customer base for a technology he developed with professors Gregory Stephanopoulos and Anthony Sinskey. The group received a J-WAFS Solutions grant in 2021 for their microbial platform that converts food waste from the dairy industry into valuable products. “As a scientist with no prior experience in entrepreneurship, the program introduced me to important concepts and tools for conducting customer interviews and adopting a new mindset,” notes Katsimpouras. “Most importantly, it encouraged me to get out of the building and engage in interviews with potential customers and stakeholders, providing me with invaluable insights and a deeper understanding of my industry,” he adds. These interviews also helped connect the team with companies willing to provide resources to test and improve their technology — a critical step to the scale-up of any lab invention.In the case of Professor Cem Tasan’s research group in the Department of Materials Science and Engineering, the I-Corps program led them to the J-WAFS Solutions grant, instead of the other way around. Tasan is currently working with postdoc Onur Guvenc on a J-WAFS Solutions project to manufacture formable sheet metal by consolidating steel scrap without melting, thereby reducing water use compared to traditional steel processing. Before applying for the Solutions grant, Guvenc took part in NE I-Corps. Like Katsimpouras, Guvenc benefited from the interaction with industry. “This program required me to step out of the lab and engage with potential customers, allowing me to learn about their immediate challenges and test my initial assumptions about the market,” Guvenc recalls. “My interviews with industry professionals also made me aware of the connection between water consumption and steelmaking processes, which ultimately led to the J-WAFS 2023 Solutions Grant,” says Guvenc.After completing the Spark program, participants may be eligible to apply for the Fusion program, which provides microgrants of up to $1,500 to conduct further customer discovery. The Fusion program is self-paced, requiring teams to conduct 12 additional customer interviews and craft a final presentation summarizing their key learnings. Professor Patrick Doyle’s J-WAFS Solutions team completed the Spark and Fusion programs at MIT. Most recently, their team was accepted to join the NSF I-Corps National program with a $50,000 award. The intensive program requires teams to complete an additional 100 customer discovery interviews over seven weeks. Located in the Department of Chemical Engineering, the Doyle lab is working on a sustainable microparticle hydrogel system to rapidly remove micropollutants from water. The team’s focus has expanded to higher value purifications in amino acid and biopharmaceutical manufacturing applications. Devashish Gokhale PhD ’24 worked with Doyle on much of the underlying science.“Our platform technology could potentially be used for selective separations in very diverse market segments, ranging from individual consumers to large industries and government bodies with varied use-cases,” Gokhale explains. He goes on to say, “The I-Corps Spark program added significant value by providing me with an effective framework to approach this problem … I was assigned a mentor who provided critical feedback, teaching me how to formulate effective questions and identify promising opportunities.” Gokhale says that by the end of Spark, the team was able to identify the best target markets for their products. He also says that the program provided valuable seminars on topics like intellectual property, which was helpful in subsequent discussions the team had with MIT’s Technology Licensing Office.Another member of Doyle’s team, Arjav Shah, a recent PhD from MIT’s Department of Chemical Engineering and a current MBA candidate at the MIT Sloan School of Management, is spearheading the team’s commercialization plans. Shah attended Fusion last fall and hopes to lead efforts to incorporate a startup company called hydroGel.  “I admire the hypothesis-driven approach of the I-Corps program,” says Shah. “It has enabled us to identify our customers’ biggest pain points, which will hopefully lead us to finding a product-market fit.” He adds “based on our learnings from the program, we have been able to pivot to impact-driven, higher-value applications in the food processing and biopharmaceutical industries.” Postdoc Luca Mazzaferro will lead the technical team at hydroGel alongside Shah.In a different project, Qinmin Zheng, a postdoc in the Department of Civil and Environmental Engineering, is working with Professor Andrew Whittle and Lecturer Fábio Duarte. Zheng plans to take the Fusion course this fall to advance their J-WAFS Solutions project that aims to commercialize a novel sensor to quantify the relative abundance of major algal species and provide early detection of harmful algal blooms. After completing Spark, Zheng says he’s “excited to participate in the Fusion program, and potentially the National I-Corps program, to further explore market opportunities and minimize risks in our future product development.”Economic and societal benefitsCommercializing technologies developed at MIT is one of the ways J-WAFS helps ensure that MIT research advances will have real-world impacts in water and food systems. Since its inception, the J-WAFS Solutions program has awarded 28 grants (including renewals), which have supported 19 projects that address a wide range of global water and food challenges. The program has distributed over $4 million to 24 professors, 11 research staff, 15 postdocs, and 30 students across MIT. Nearly half of all J-WAFS Solutions projects have resulted in spinout companies or commercialized products, including eight companies to date plus two open-source technologies.Nona Technologies is an example of a J-WAFS spinout that is helping the world by developing new approaches to produce freshwater for drinking. Desalination — the process of removing salts from seawater — typically requires a large-scale technology called reverse osmosis. But Nona created a desalination device that can work in remote off-grid locations. By separating salt and bacteria from water using electric current through a process called ion concentration polarization (ICP), their technology also reduces overall energy consumption. The novel method was developed by Jongyoon Han, professor of electrical engineering and biological engineering, and research scientist Junghyo Yoon. Along with Bruce Crawford, a Sloan MBA alum, Han and Yoon created Nona Technologies to bring their lightweight, energy-efficient desalination technology to the market.“My feeling early on was that once you have technology, commercialization will take care of itself,” admits Crawford. The team completed both the Spark and Fusion programs and quickly realized that much more work would be required. “Even in our first 24 interviews, we learned that the two first markets we envisioned would not be viable in the near term, and we also got our first hints at the beachhead we ultimately selected,” says Crawford. Nona Technologies has since won MIT’s $100K Entrepreneurship Competition, received media attention from outlets like Newsweek and Fortune, and hired a team that continues to further the technology for deployment in resource-limited areas where clean drinking water may be scarce. Food-borne diseases sicken millions of people worldwide each year, but J-WAFS researchers are addressing this issue by integrating molecular engineering, nanotechnology, and artificial intelligence to revolutionize food pathogen testing. Professors Tim Swager and Alexander Klibanov, of the Department of Chemistry, were awarded one of the first J-WAFS Solutions grants for their sensor that targets food safety pathogens. The sensor uses specialized droplets that behave like a dynamic lens, changing in the presence of target bacteria in order to detect dangerous bacterial contamination in food. In 2018, Swager launched Xibus Systems Inc. to bring the sensor to market and advance food safety for greater public health, sustainability, and economic security.“Our involvement with the J-WAFS Solutions Program has been vital,” says Swager. “It has provided us with a bridge between the academic world and the business world and allowed us to perform more detailed work to create a usable application,” he adds. In 2022, Xibus developed a product called XiSafe, which enables the detection of contaminants like salmonella and listeria faster and with higher sensitivity than other food testing products. The innovation could save food processors billions of dollars worldwide and prevent thousands of food-borne fatalities annually.J-WAFS Solutions companies have raised nearly $66 million in venture capital and other funding. Just this past June, J-WAFS spinout SiTration announced that it raised an $11.8 million seed round. Jeffrey Grossman, a professor in MIT’s Department of Materials Science and Engineering, was another early J-WAFS Solutions grantee for his work on low-cost energy-efficient filters for desalination. The project enabled the development of nanoporous membranes and resulted in two spinout companies, Via Separations and SiTration. SiTration was co-founded by Brendan Smith PhD ’18, who was a part of the original J-WAFS team. Smith is CEO of the company and has overseen the advancement of the membrane technology, which has gone on to reduce cost and resource consumption in industrial wastewater treatment, advanced manufacturing, and resource extraction of materials such as lithium, cobalt, and nickel from recycled electric vehicle batteries. The company also recently announced that it is working with the mining company Rio Tinto to handle harmful wastewater generated at mines.But it’s not just J-WAFS spinout companies that are producing real-world results. Products like the ECC Vial — a portable, low-cost method for E. coli detection in water — have been brought to the market and helped thousands of people. The test kit was developed by MIT D-Lab Lecturer Susan Murcott and Professor Jeffrey Ravel of the MIT History Section. The duo received a J-WAFS Solutions grant in 2018 to promote safely managed drinking water and improved public health in Nepal, where it is difficult to identify which wells are contaminated by E. coli. By the end of their grant period, the team had manufactured approximately 3,200 units, of which 2,350 were distributed — enough to help 12,000 people in Nepal. The researchers also trained local Nepalese on best manufacturing practices.“It’s very important, in my life experience, to follow your dream and to serve others,” says Murcott. Economic success is important to the health of any venture, whether it’s a company or a product, but equally important is the social impact — a philosophy that J-WAFS research strives to uphold. “Do something because it’s worth doing and because it changes people’s lives and saves lives,” Murcott adds.As J-WAFS prepares to celebrate its 10th anniversary this year, we look forward to continued collaboration with MIT’s many I&E programs to advance knowledge and develop solutions that will have tangible effects on the world’s water and food systems.Learn more about the J-WAFS Solutions program and about innovation and entrepreneurship at MIT. More

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    Tracking emissions to help companies reduce their environmental footprint

    Amidst a global wave of corporate pledges to decarbonize or reach net-zero emissions, a system for verifying actual greenhouse gas reductions has never been more important. Context Labs, founded by former MIT Sloan Fellow and serial entrepreneur Dan Harple SM ’13, is rising to meet that challenge with an analytics platform that brings more transparency to emissions data.The company’s platform adds context to data from sources like equipment sensors and satellites, provides third-party verification, and records all that information on a blockchain. Context Labs also provides an interactive view of emissions across every aspect of a company’s operations, allowing leaders to pinpoint the dirtiest parts of their business.“There’s an old adage: Unless you measure something, you can’t change it,” says Harple, who is the firm’s CEO. “I think of what we’re doing as an AI-driven digital lens into what’s happening across organizations. Our goal is to help the planet get better, faster.”Context Labs is already working with some of the largest energy companies in the world — including EQT, Williams Companies, and Coterra Energy — to verify emissions reductions. A partnership with Microsoft, announced at last year’s COP28 United Nations climate summit, allows any organization on Microsoft’s Azure cloud to integrate their sensor data into Context Lab’s platform to get a granular view of their environmental impact.Harple says the progress enables more informed sustainability initiatives at scale. He also sees the work as a way to combat overly vague statements about sustainable practices that don’t lead to actual emissions reductions, or what’s known as “greenwashing.”“Just producing data isn’t good enough, and our customers realize that, because they know even if they have good intentions to reduce emissions, no one is going to believe them,” Harple says. “One way to think about our platform is as antigreenwashing insurance, because if you get attacked for your emissions, we unbundle the data like it’s in shrink-wrap and roll it back through time on the blockchain. You can click on it and see exactly where and how it was measured, monitored, timestamped, its serial number, everything. It’s really the gold standard of proof.”An unconventional master’sHarple came to MIT as a serial founder whose companies had pioneered several foundational internet technologies, including real-time video streaming technology still used in applications like Zoom and Netflix, as well as some of the core technology for the popular Chinese microblogging website Weibo.Harple’s introduction to MIT started with a paper he wrote for his venture capital contacts in the U.S. to make the case for investment in the Netherlands, where he was living with his family. The paper caught the attention of MIT Professor Stuart Madnick, the John Norris Maguire Professor of Information Technology at the MIT Sloan School of Management, who suggested Harple come to MIT as a Sloan Fellow to further develop his ideas about what makes a strong innovation ecosystem.Having successfully founded and exited multiple companies, Harple was not a typical MIT student when he began the Sloan Fellows program in 2011. At one point, he held a summit at MIT for a group of leading Dutch entrepreneurs and government officials that included tours of major labs and a meeting with former MIT President L. Rafael Reif.“Everyone was super enamored with MIT, and that kicked off what became a course that I started at MIT called REAL, Regional Entrepreneurial Acceleration Lab,” Harple says. REAL was eventually absorbed by what is now REAP — the Regional Entrepreneurship Acceleration Program, which has worked with communities around the world.Harple describes REAL as a framework vehicle to put his theories on supporting innovation into action. Over his time at MIT, which also included collaborating with the Media Lab, he systematized those theories into what he calls pentalytics, which is a way to measure and predict the resilience of innovation ecosystems.“My sense was MIT should be analytical and data-driven,” Harple says. “The thesis I wrote was a framework for AI-driven network graph analytics. So, you can model things using analytics, and you can use AI to do predictive analytics to see where the innovation ecosystem is going to thrive.”Once Harple’s pentalytics theory was established, he wanted to put it to the test with a company. His initial idea for Context Labs was to build a verification platform to combat fake news, deepfakes, and other misinformation on the internet. Around 2018, Harple met climate investor Jeremy Grantham, who he says helped him realize the most important data are about the planet. Harple began to believe that U.S. Environmental Protection Agency (EPA) emissions estimates for things like driving a car or operating an oil rig were just that — estimates — and left room for improvement.“Our approach was very MIT-ish,” Harple says. “We said, ‘Let’s, measure it and let’s monitor it, and then let’s contextualize that data so you can never go back and say they faked it. I think there’s a lot of fakery that’s happened, and that’s why the voluntary carbon markets cratered in the last year. Our view is they cratered because the data wasn’t empirical enough.”Context Labs’ solution starts with a technology platform it calls Immutably that continuously combines disparate data streams, encrypts that information, and records it on a blockchain. Immutably also verifies the information with one or more third parties. (Context Labs has partnered with the global accounting firm KPMG.)On top of Immutably, Context Labs has built applications, including a product called Decarbonization-as-a-Service (DaaS), which uses Immutably’s data to give companies a digital twin of their entire operations. Customers can use DaaS to explore the emissions of their assets and create a certificate of verified CO2-equivalent emissions, which can be used in carbon credit markets.Putting emissions data into contextContext Labs is working with oil and gas companies, utilities, data centers, and large industrial operators, some using the platform to analyze more than 3 billion data points each day. For instance, EQT, the largest natural gas producer in the U.S., uses Context Labs to verify its lower-emission products and create carbon credits. Other customers include the nonprofits Rocky Mountain Institute and the Environmental Defense Fund.“I often get asked how big the total addressable market is,” Harple says. “My view is it’s the largest market in history. Why? Because every country needs a decarbonization plan, along with instrumentation and a digital platform to execute, as does every company.”With its headquarters in Kendall Square in Cambridge, Massachusetts, Context Labs is also serving as a test for Harple’s pentalytics theory for innovation ecosystems. It also has operations in Houston and Amsterdam.“This company is a living lab for pentalytics,” Harple says. “I believe Kendall Square 1.0 was factory buildings, Kendall Square 2.0 is biotech, and Kendall Square 3.0 will be climate tech.” More

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    Pioneering the future of materials extraction

    The next time you cook pasta, imagine that you are cooking spaghetti, rigatoni, and seven other varieties all together, and they need to be separated onto 10 different plates before serving. A colander can remove the water — but you still have a mound of unsorted noodles. Now imagine that this had to be done for thousands of tons of pasta a day. That gives you an idea of the scale of the problem facing Brendan Smith PhD ’18, co-founder and CEO of SiTration, a startup formed out of MIT’s Department of Materials Science and Engineering (DMSE) in 2020. SiTration, which raised $11.8 million in seed capital led by venture capital firm 2150 earlier this month, is revolutionizing the extraction and refining of copper, cobalt, nickel, lithium, precious metals, and other materials critical to manufacturing clean-energy technologies such as electric motors, wind turbines, and batteries. Its initial target applications are recovering the materials from complex mining feed streams, spent lithium-ion batteries from electric vehicles, and various metals refining processes. The company’s breakthrough lies in a new silicon membrane technology that can be adjusted to efficiently recover disparate materials, providing a more sustainable and economically viable alternative to conventional, chemically intensive processes. Think of a colander with adjustable pores to strain different types of pasta. SiTration’s technology has garnered interest from industry players, including mining giant Rio Tinto. Some observers may question whether targeting such different industries could cause the company to lose focus. “But when you dig into these markets, you discover there is actually a significant overlap in how all of these materials are recovered, making it possible for a single solution to have impact across verticals,” Smith says.Powering up materials recoveryConventional methods of extracting critical materials in mining, refining, and recycling lithium-ion batteries involve heavy use of chemicals and heat, which harm the environment. Typically, raw ore from mines or spent batteries are ground into fine particles before being dissolved in acid or incinerated in a furnace. Afterward, they undergo intensive chemical processing to separate and purify the valuable materials. “It requires as much as 10 tons of chemical input to produce one ton of critical material recovered from the mining or battery recycling feedstock,” says Smith. Operators can then sell the recaptured materials back into the supply chain, but suffer from wide swings in profitability due to uncertain market prices. Lithium prices have been the most volatile, having surged more than 400 percent before tumbling back to near-original levels in the past two years. Despite their poor economics and negative environmental impact, these processes remain the state of the art today. By contrast, SiTration is electrifying the critical-materials recovery process, improving efficiency, producing less chemical waste, and reducing the use of chemicals and heat. What’s more, the company’s processing technology is built to be highly adaptable, so it can handle all kinds of materials. The core technology is based on work done at MIT to develop a novel type of membrane made from silicon, which is durable enough to withstand harsh chemicals and high temperatures while conducting electricity. It’s also highly tunable, meaning it can be modified or adjusted to suit different conditions or target specific materials. SiTration’s technology also incorporates electro-extraction, a technique that uses electrochemistry to further isolate and extract specific target materials. This powerful combination of methods in a single system makes it more efficient and effective at isolating and recovering valuable materials, Smith says. So depending on what needs to be separated or extracted, the filtration and electro-extraction processes are adjusted accordingly. “We can produce membranes with pore sizes from the molecular scale up to the size of a human hair in diameter, and everything in between. Combined with the ability to electrify the membrane and separate based on a material’s electrochemical properties, this tunability allows us to target a vast array of different operations and separation applications across industrial fields,” says Smith. Efficient access to materials like lithium, cobalt, and copper — and precious metals like platinum, gold, silver, palladium, and rare-earth elements — is key to unlocking innovation in business and sustainability as the world moves toward electrification and away from fossil fuels.“This is an era when new materials are critical,” says Professor Jeffrey Grossman, co-founder and chief scientist of SiTration and the Morton and Claire Goulder and Family Professor in Environmental Systems at DMSE. “For so many technologies, they’re both the bottleneck and the opportunity, offering tremendous potential for non-incremental advances. And the role they’re having in commercialization and in entrepreneurship cannot be overstated.”SiTration’s commercial frontierSmith became interested in separation technology in 2013 as a PhD student in Grossman’s DMSE research group, which has focused on the design of new membrane materials for a range of applications. The two shared a curiosity about separation of critical materials and a hunger to advance the technology. After years of study under Grossman’s mentorship, and with support from several MIT incubators and foundations including the Abdul Latif Jameel Water and Food Systems Lab’s Solutions Program, the Deshpande Center for Technological Innovation, the Kavanaugh Fellowship, MIT Sandbox, and Venture Mentoring Service, Smith was ready to officially form SiTration in 2020. Grossman has a seat on the board and plays an active role as a strategic and technical advisor. Grossman is involved in several MIT spinoffs and embraces the different imperatives of research versus commercialization. “At SiTration, we’re driving this technology to work at scale. There’s something super exciting about that goal,” he says. “The challenges that come with scaling are very different than the challenges that come in a university lab.” At the same time, although not every research breakthrough becomes a commercial product, open-ended, curiosity-driven knowledge pursuit holds its own crucial value, he adds.It has been rewarding for Grossman to see his technically gifted student and colleague develop a host of other skills the role of CEO demands. Getting out to the market and talking about the technology with potential partners, putting together a dynamic team, discovering the challenges facing industry, drumming up support, early on — those became the most pressing activities on Smith’s agenda. “What’s most fun to me about being a CEO of an early-stage startup is that there are 100 different factors, most people-oriented, that you have to navigate every day. Each stakeholder has different motivations and objectives. And you basically try to fit that all together, to create value for our partners and customers, the company, and for society,” says Smith. “You start with just an idea, and you have to keep leveraging that to form a more and more tangible product, to multiply and progress commercial relationships, and do it all at an ever-expanding scale.” MIT DNA runs deep in the nine-person company, with DMSE grad and former Grossman student Jatin Patil as director of product; Ahmed Helal, from MIT’s Department of Mechanical Engineering, as vice president of research and development; Daniel Bregante, from the Department of Chemistry, as VP of technology; and Sarah Melvin, from the departments of Physics and Political Science, as VP of strategy and operations. Melvin is the first hire devoted to business development. Smith plans to continue expanding the team following the closing of the company’s seed round.  Strategic alliancesBeing a good communicator was important when it came to securing funding, Smith says. SiTration received $2.35 million in pre-seed funding in 2022 led by Azolla Ventures, which reserves its $239 million in investment capital for startups that would not otherwise easily obtain funding. “We invest only in solution areas that can achieve gigaton-scale climate impact by 2050,” says Matthew Nordan, a general partner at Azolla and now SiTration board member. The MIT-affiliated E14 Fund also contributed to the pre-seed round; Azolla and E14 both participated in the recent seed funding round. “Brendan demonstrated an extraordinary ability to go from being a thoughtful scientist to a business leader and thinker who has punched way above his weight in engaging with customers and recruiting a well-balanced team and navigating tricky markets,” says Nordan. One of SiTration’s first partnerships is with Rio Tinto, one of the largest mining companies in the world. As SiTration evaluated various uses cases in its early days, identifying critical materials as its target market, Rio Tinto was looking for partners to recover valuable metals such as cobalt and copper from the wastewater generated at mines. These metals were typically trapped in the water, creating harmful waste and resulting in lost revenue. “We thought this was a great innovation challenge and posted it on our website to scout for companies to partner with who can help us solve this water challenge,” said Nick Gurieff, principal advisor for mine closure, in an interview with MIT’s Industrial Liaison Program in 2023. At SiTration, mining was not yet a market focus, but Smith couldn’t help noticing that Rio Tinto’s needs were in alignment with what his young company offered. SiTration submitted its proposal in August 2022. Gurieff said SiTration’s tunable membrane set it apart. The companies formed a business partnership in June 2023, with SiTration adjusting its membrane to handle mine wastewater and incorporating Rio Tinto feedback to refine the technology. After running tests with water from mine sites, SiTration will begin building a small-scale critical-materials recovery unit, followed by larger-scale systems processing up to 100 cubic meters of water an hour.SiTration’s focused technology development with Rio Tinto puts it in a good position for future market growth, Smith says. “Every ounce of effort and resource we put into developing our product is geared towards creating real-world value. Having an industry-leading partner constantly validating our progress is a tremendous advantage.”It’s a long time from the days when Smith began tinkering with tiny holes in silicon in Grossman’s DMSE lab. Now, they work together as business partners who are scaling up technology to meet a global need. Their joint passion for applying materials innovation to tough problems has served them well. “Materials science and engineering is an engine for a lot of the innovation that is happening today,” Grossman says. “When you look at all of the challenges we face to make the transition to a more sustainable planet, you realize how many of these are materials challenges.” More

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    Startup aims to transform the power grid with superconducting transmission lines

    Last year in Woburn, Massachusetts, a power line was deployed across a 100-foot stretch of land. Passersby wouldn’t have found much interesting about the installation: The line was supported by standard utility poles, the likes of which most of us have driven by millions of times. In fact, the familiarity of the sight is a key part of the technology’s promise.The lines are designed to transport five to 10 times the amount of power of conventional transmission lines, using essentially the same footprint and voltage level. That will be key to helping them overcome the regulatory hurdles and community opposition that has made increasing transmission capacity nearly impossible across large swaths of the globe, particularly in America and Europe, where new power distribution systems play a vital role in the shift to renewable energy and the resilience of the grid.The lines are the product of years of work by the startup VEIR, which was co-founded by Tim Heidel ’05, SM ’06, SM ’09, PhD ’10. They make use of superconducting cables and a proprietary cooling system that will enable initial transmission capacity up to 400 megawatts and, in future versions, up to several gigawatts.“We can deploy much higher power levels at much lower voltage, and so we can deploy the same high power but with a footprint and visual impact that is far less intrusive, and therefore can overcome a lot of the public opposition as well as siting and permitting barriers,” Heidel says.VEIR’s solution comes at a time when more than 10,000 renewable energy projects at various stages of development are seeking permission to connect to U.S. grids. The White House has said the U.S. must more than double existing regional transmission capacity in order to reach 2035 decarbonization goals.All of this comes as electricity demand is skyrocketing amid the increasing use of data centers and AI, and the electrification of everything from passenger vehicles to home heating systems.Despite those trends, building high-power transmission lines remains stubbornly difficult.“Building high-power transmission infrastructure can take a decade or more, and there’s been quite a few examples of projects that folks have had to abandon because they realize that there’s just so much opposition, or there’s too much complexity to pull it off cost effectively,” Heidel says. “We can drop down in voltage but carry the same amount of power because we can build systems that operate at much higher current levels, and that’s how our lines are able to melt into the background and avoid the same opposition.”Heidel says VEIR has built a pipeline of interested customers including utilities, data center operators, industrial companies, and renewable energy developers. VEIR is aiming to complete its first commercial-scale pilot carrying high power in 2026.A career in energyOver more than a decade at MIT, Heidel went from learning about the fundamentals of electrical engineering to studying the electric grid and the power sector more broadly. That journey included earning a bachelor’s, master’s, and PhD from MIT’s Department of Electrical Engineering and Computer Science as well as a master’s in MIT’s Technology and Policy Program, which he earned while working toward his PhD.“I got the energy bug and started to focus exclusively on energy and climate in graduate school,” Heidel says.Following his PhD, Heidel was named research director of MIT’s Future of the Electric Grid study, which was completed in 2011.“That was a fantastic opportunity at the outset of my career to survey the entire landscape and understand challenges facing the power grid and the power sector more broadly,” Heidel says. “It gave me a good foundation for understanding the grid, how it works, who’s involved, how decisions get made, how expansion works, and it looked out over the next 30 years.”After leaving MIT, Heidel worked at the Department of Energy’s Advanced Research Projects Agency-Energy (ARPA-E) and then at Bill Gates’ Breakthrough Energy Ventures (BEV) investment firm, where he continued studying transmission.“Just about every single decarbonization scenario and study that’s been published in the last two decades concludes that to achieve aggressive greenhouse gas emissions reductions, we’re going to have to double or triple the scale of power grids around the world,” Heidel says. “But when we looked at the data on how fast grids were being expanded, the ease with which transmission lines could be built, the cost of building new transmission, just about every indicator was heading in the wrong direction. Transmission was getting more expensive over time and taking longer to build. We desperately need to find a new solution.”Unlike traditional transmission lines made from steel and aluminum, VEIR’s transmission lines leverage decades of progress in the development of high-temperature superconducting tapes and other materials. Some of that progress has been driven by the nuclear fusion industry, which incorporates superconducting materials into some of their nuclear reactor designs.But the core innovation at VEIR is the cooling system. VEIR co-founder and advisor Steve Ashworth developed the rough idea for the cooling system more than 15 years ago at Los Alamos National Laboratory as part of a larger Department of Energy-funded research project. When the project was shut down, the idea was largely forgotten.Heidel and others at Breakthrough Energy Ventures became aware of the innovation in 2019 while researching transmission. Today VEIR’s system is passively cooled with nitrogen, which runs through a vacuum-insulated pipe that surrounds a superconducting cable. Heat exchange units are also used on some transmission towers.Heidel says transmission lines designed to carry that much power are typically far bigger than VEIR’s design, and other attempts at shrinking the footprint of high-power lines were limited to short distances underground.“High power requires high voltage, and high voltage requires tall towers and wide right of ways, and those tall towers and those wide right of ways are deeply unpopular,” Heidel says. “That is a universal truth across just about the entire world.”Moving power around the worldVEIR’s first alternating current (AC) overhead product line is capable of transmission capacities up to 400 megawatts and voltages of up to 69 kilovolts, and the company plans to scale to higher voltage and higher-power products in the future, including direct current (DC) lines.VEIR will sell its equipment to the companies installing transmission lines, with a primary focus on the U.S. market.In the longer term, Heidel believes VEIR’s technology is needed as soon as possible to meet rising electricity demands and new renewable energy projects around the globe. 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    New MIT-LUMA Lab created to address climate challenges in the Mediterranean region

    The MIT School of Architecture and Planning (SA+P) and the LUMA Foundation announced today the establishment of the MIT-LUMA Lab to advance paradigm-shifting innovations at the nexus of art, science, technology, conservation, and design. The aim is to empower innovative thinkers to realize their ambitions, support local communities as they seek to address climate-related issues, and scale solutions to pressing challenges facing the Mediterranean region.  The main programmatic pillars of the lab will be collaborative scholarship and research around design, new materials, and sustainability; scholar exchange and education collaborations between the two organizations; innovation and entrepreneurship activities to transfer new ideas into practical applications; and co-production of exhibitions and events. The hope is that this engagement will create a novel model for other institutions to follow to craft innovative solutions to the leading challenge of our time.The MIT-LUMA Lab draws on an establishing gift from the LUMA Foundation, a nonprofit organization based in Zurich formed by Maja Hoffmann in 2004 to support contemporary artistic production. The foundation supports a range of multidisciplinary projects that increase understanding of the environment, human rights, education, and culture.These themes are explored through programs organized by LUMA Arles, a project begun in 2013 and housed on a 27-acre interdisciplinary campus known as the Parc des Ateliers in Arles, France, an experimental site of exhibitions, artists’ residencies, research laboratories, and educational programs.“The Luma Foundation is committed to finding ways to address the current climate emergencies we are facing, focusing on exploring the potentials that can be found in diversity and engagement in every possible form,” says Maja Hoffmann, founder and president of the LUMA Foundation. “Cultural diversity, pluralism, and biodiversity feature at the top of our mission and our work is informed by these concepts.” A focus on the Mediterranean region“The culturally rich area of the Mediterranean, which has produced some of the most remarkable civilizational paradigms across geographies and historical periods, plays an important role in our thinking. Focusing the efforts of the MIT-LUMA Lab on the Mediterranean means extending the possibilities for positive change throughout other global ecosystems,” says Hoffmann. “Our projects of LUMA Arles and its research laboratory on materials and natural resources, the Atelier Luma, our position in one of Europe’s most important natural reserves, in conjunction with the expertise and forward-thinking approach of MIT, define the perfect framework that will allow us to explore new frontiers and devise novel ways to tackle our most significant civilizational risks,” she adds. “Supporting the production of new forms of knowledge and practices, and with locations in Cambridge and in Arles, our collaboration and partnership with MIT will generate solutions and models for the future, for the generations to come, in order to provide them the same and even better opportunities that what we have experienced.”“We know we do not have all the answers at MIT, but we do know how to ask the right questions, how to design effective experiments, and how to build meaningful collaborations,” says Hashim Sarkis, dean of SA+P, which will host the lab. “I am grateful to the LUMA Foundation for offering support for faculty research deployment designed to engage local communities and create jobs, for course development to empower our faculty to teach classes centered on these issues, and for students who seek to dedicate their lives and careers to sustainability. We also look forward to hosting fellows and researchers from the foundation to strengthen our collaboration,” he adds.The Mediterranean region, the MIT-LUMA Lab’s focus, is one of the world’s most vital and fragile global commons. The future of climate relies on the sustainability of the region’s forests, oceans, and deserts that have for millennia created the environmental conditions and system-regulating functions necessary for life on Earth. Those who live in these areas are often the most severely affected by even relatively modest changes in the climate. Climate research and action: A priority at MITTo reverse negative trends and provide a new approach to addressing the climate crisis in these vast areas, SA+P is establishing international collaborations that bring know-how to the field, and in turn to learn from the communities and groups most challenged by climate impacts.The MIT-LUMA Lab is the first in what is envisioned as a series of regionally focused labs at SA+P under the conceptual aegis of a collaborative platform called Our Global Commons. This project will support progress on today’s climate challenges by focusing on community empowerment, long-term local collaborations around research and education, and job creation. Faculty-led fieldwork, engagements with local stakeholders, and student involvement will be the key elements.The creation of Our Global Commons comes as MIT works to dramatically expand its efforts to address climate change. In February 2024, President Sally Kornbluth announced the Climate Project at MIT, a major new initiative to mobilize the Institute’s resources and capabilities to research, develop, deploy, and scale-up new climate solutions. The Institute will hire its first-ever vice president for climate to oversee the new effort. “With the Climate Project at MIT, we aim to help make a decisive difference, at scale, on crucial global climate challenges — and we can only do that by engaging with outstanding colleagues around the globe,” says Kornbluth. “By connecting us to creative thinkers steeped in the cultural and environmental history and emerging challenges of the Mediterranean region, the MIT-LUMA Lab promises to spark important new ideas and collaborations.”“We are excited that the LUMA team will be joining in MIT’s engagement with climate issues, especially given their expertise in advancing vital work at the intersection of art and science, and their long-standing commitment to expanding the frontiers of sustainability and biodiversity,” says Sarkis. “With climate change upending many aspects of our society, the time is now for us to reaffirm and strengthen our SA+P tradition of on-the-ground work with and for communities around the world. Shared efforts among local communities, governments and corporations, and academia are necessary to bring about real change.” More

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    MIT scholars will take commercial break with entrepreneurial scholarship

    Two MIT scholars, each with a strong entrepreneurial drive, have received 2024 Kavanaugh Fellowship awards, advancing their quest to turn pioneering research into profitable commercial enterprises.The Kavanaugh Translational Fellows Program gives scholars training to lead organizations that will bring their research to market. PhD candidates Grant Knappe and Arjav Shah are this year’s recipients. Knappe is developing a drug delivery platform for an emerging class of medicines called nucleic acid therapeutics. Shah is using hydrogel microparticles to clean up water polluted by heavy metals and other contaminants.Knappe and Shah will begin their fellowship with years of entrepreneurial expertise under their belts. They’ve developed and refined their business plans through MIT’s innovation ecosystem, including the Sandbox, the Legatum Center, the Venture Mentoring Service, the National Science Foundation’s I-Corps Program, and Blueprint by The Engine. Now, the yearlong Kavanaugh Fellowship will give the scholars time to focus exclusively on testing their business plans and exercising decision-making skills — critical to startup success — with the guidance of MIT mentors.“It’s a testament to the support and direction they’ve received from the MIT community that their entrepreneurial aspirations have evolved and matured over time,” says Michael J. Cima, program director for the Kavanaugh program and the David H. Koch Professor of Engineering in the Department of Materials Science and Engineering.Founded in 2016, the Kavanaugh program was instrumental in helping past fellows launch several robust startups, including low-carbon cement manufacturer Sublime Systems and SiTration, which is using a new type of filtration membrane to extract critical materials such as lithium.A safer way to deliver breakthrough medicinesNucleic acid therapeutics, including mRNA and CRISPR, are disrupting today’s clinical landscape thanks to their promise of targeting disease treatment according to genetic blueprints. But the first methods of delivering these molecules to the body used viruses as their transport, raising patient safety concerns.“Humans have figured out how to engineer certain viruses found in nature to deliver specific cargoes [for disease treatment],” says Knappe. “But because they look like viruses, the human immune system sees them as a danger signal and creates an immune reaction that can be harmful to patients.”Given the safety profile issues of viral delivery, researchers turned to non-viral technologies that use lipid nanoparticle technology, a mixture of different lipid-like materials, assembled into particles to protect the mRNA therapeutic from getting degraded before it reaches a cell of interest. “Because they don’t look like viruses there, the immune system generally tolerates them,” adds Knappe.Recent data show lipid nanoparticles can now target the lung, opening the potential for novel treatments of deadly cancers and other diseases.Knappe’s work in MIT’s Bathe BioNanoLab focused on building such a non-viral delivery platform based on a different technology: nucleic acid nanoparticles, which combine the attractive components of both viral and non-viral systems. Knappe will spend his Kavanaugh Fellowship year developing proof-of-concept data for his drug delivery method and building the team and funding needed to commercialize the technology.A PhD candidate in the Department of Chemical Engineering (ChemE), Knappe was initially attracted to MIT because of its intellectual openness. “You can work with any faculty member in other departments. I wasn’t restricted to the chemical engineering faculty,” says Knappe, whose supervisor, Professor Mark Bathe, is in the Department of Biological Engineering.Knappe, who is from New Jersey, welcomes the challenges that will come in his Kavanaugh year, including the need to pinpoint the right story that will convince venture capitalists and other funders to bet on his technology. Attracting talent is also top of mind. “How do you convince really talented people that have a lot of opportunities to work on what you work on? Building the first team is going to be critical,” he says. The network Knappe has been building in his years at MIT is paying dividends now.Targeting “forever chemicals” in waterThat network includes Shah. The two fellows met when they worked on the MIT Science Policy Review, a student-run journal concerned with the intersection of science, technology, and policy. Knappe and Shah did not compete directly academically but used their biweekly coffee walks as a welcome sounding board. Naturally, they were pleased when they found out they had both been chosen for the Kavanaugh Fellowship. So far, they have been too busy to celebrate over a beer.“We are good collaborators with research, as well,” says Shah. “Now we’re going on this entrepreneurial journey together. It’s been exciting.”Shah is a PhD candidate in ChemE’s Chemical Engineering Practice program. He got interested in the global imperative for cleaner water at a young age. His hometown of Surat is the heart of India’s textile industry. “Growing up, it wasn’t hard to see the dye-colored water flowing into your rivers and streams,” Shah says. “Playing a role in fostering positive change in water treatment fills me with a profound sense of purpose.”Shah’s work, broadly, is to clean toxic chemicals called micropollutants from water in an efficient and sustainable manner. “It’s humanly impossible to turn a blind eye to our water problems,” he says, which can be categorized as accessibility, availability, and quality. Water problems are global and complex, not just because of the technological challenges but also sociopolitical ones, he adds.Manufactured chemicals called per- and polyfluoroalkyl substances (PFAS), or “forever chemicals,” are in the news these days. PFAS, which go into making nonstick cookware and waterproof clothing, are just one of more than 10,000 such emerging contaminants that have leached into water streams. “These are extremely difficult to remove using existing systems because of their chemical diversity and low concentrations,” Shah says. “The concentrations are akin to dropping an aspirin tablet in an Olympic-sized swimming pool.” But no less toxic for that.In the lab at MIT, Shah is working with Devashish Gokhale, a fellow PhD student, and Patrick S. Doyle, the Robert T. Haslam (1911) Professor of Chemical Engineering, to commercialize an innovative microparticle technology, hydroGel, to remove these micropollutants in an effective, facile, and sustainable manner. Hydrogels are a broad class of polymer materials that can hold large quantities of water.“Our materials are like Boba beads. We are trying to save the world with our Boba beads,” says Shah with a laugh. “And we have functionalized these particles with tunable chemistries to target different micropollutants in a single unit operation.”Due to its outsized environmental impact, industrial water is the first application Shah is targeting. Today, wastewater treatment emits more than 3 percent of global carbon dioxide emissions, which is more than the shipping industry’s emissions, for example. The current state of the art for removing micropollutants in the industry is to use activated carbon filters. “[This technology] comes from coal, so it’s unsustainable,” Shah says. And the activated carbon filters are hard to reuse. “Our particles are reusable, theoretically infinitely.”“I’m very excited to be able to take advantage of the mentorship we have from the Kavanaugh team to take this technology to its next inflection point, so that we are ready to go out in the market and start making a huge impact,” he says.A dream communityShah and Knappe have become adept at navigating the array of support and mentorship opportunities MIT has to offer. Shah worked with a small team of seasoned professionals in the water space from the MIT Venture Mentoring Service. “They’ve helped us every step of the way as we think about commercializing the technology,” he says.Shah worked with MIT Sandbox, which provides a seed grant to help find the right product-market fit. He is also a fellow with the Legatum Center for Development and Entrepreneurship, which focuses on entrepreneurship in emerging countries in growth markets.“We’re exploring the potential for this technology and its application in a lot of different markets, including India. Because that’s close to my heart,” Shah says. “The Legatum community has been unique, where you can have those extremely hard conversations, confront yourself with those fears, and then talk it out with the group of fellows.”The Abdul Latif Jameel Water and Food Systems Lab, or J-WAFS, has been an integral part of Shah’s journey with research and commercialization support through its Solutions Grant and a travel award to the Stockholm World Water Week in August 2023.Knappe has also taken advantage of many innovation programs, including MIT’s Blueprint by the Engine, which helps researchers explore commercial opportunities of their work, plus programs outside of MIT but with strong on-campus ties such as Nucleate Activator and Frequency Bio.It was during one of these programs that he was inspired by two postdocs working in Bathe’s lab and spinning out biotech startups from their research, Floris Engelhardt and James Banal. Engelhardt helped spearhead Kano Therapeutics, and Banal launched Cache DNA.“I was passively absorbing and watching everything that they were going through and what they were excited about and challenged with. I still talk to them pretty regularly to this day,” Knappe says. “It’s been really great to have them as continual mentors, throughout my PhD and as I transition out of the lab.”Shah says he is grateful not only for being selected for the Kavanaugh Fellowship but to MIT as a community. “MIT has been more than a dream come true,” he says. He will have the opportunity to explore a different side of the institution as he enters the MBA program at MIT Sloan School of Management this fall. Shah expects this program, along with his Kavanaugh training, will supply the skills he needs to scale the business so it can make a difference in the world.“I always keep coming back to the question ‘How does what I do matter to the person on the street?’ This guides me to look at the bigger picture, to contextualize my research to solving important problems,” Shah says. “So many great technologies are being worked on each day, but only a minuscule fraction make it to the market.”Knappe is equally dedicated to serving a larger purpose. “With the right infrastructure, between basic fundamental science, conducted in academia, funded by government, and then translated by companies, we can make products that could improve everyone’s life across the world,” he says.Past Kavanaugh Fellows are credited with spearheading commercial outfits that have indeed made a difference. This year’s fellows are poised to follow their lead. But first they will have that beer together to celebrate. More

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    Making steel with electricity

    Steel is one of the most useful materials on the planet. A backbone of modern life, it’s used in skyscrapers, cars, airplanes, bridges, and more. Unfortunately, steelmaking is an extremely dirty process.The most common way it’s produced involves mining iron ore, reducing it in a blast furnace through the addition of coal, and then using an oxygen furnace to burn off excess carbon and other impurities. That’s why steel production accounts for around 7 to 9 percent of humanity’s greenhouse gas emissions worldwide, making it one of the dirtiest industries on the planet.Now Boston Metal is seeking to clean up the steelmaking industry using an electrochemical process called molten oxide electrolysis (MOE), which eliminates many steps in steelmaking and releases oxygen as its sole byproduct.The company, which was founded by MIT Professor Emeritus Donald Sadoway, Professor Antoine Allanore, and James Yurko PhD ’01, is already using MOE to recover high-value metals from mining waste at its Brazilian subsidiary, Boston Metal do Brasil. That work is helping Boston Metal’s team deploy its technology at commercial scale and establish key partnerships with mining operators. It has also built a prototype MOE reactor to produce green steel at its headquarters in Woburn, Massachusetts.And despite its name, Boston Metal has global ambitions. The company has raised more than $370 million to date from organizations across Europe, Asia, the Americas, and the Middle East, and its leaders expect to scale up rapidly to transform steel production in every corner of the world.“There’s a worldwide recognition that we need to act rapidly, and that’s going to happen through technology solutions like this that can help us move away from incumbent technologies,” Boston Metal Chief Scientist and former MIT postdoc Guillaume Lambotte says. “More and more, climate change is a part of our lives, so the pressure is on everyone to act fast.”To the moon and backThe origins of Boston Metal’s technology start on the moon. In the mid 2000s, Sadoway, who is the John F. Elliott Professor Emeritus of Materials Chemistry in MIT’s Department of Materials Science, received a grant from NASA to explore ways to produce oxygen for future lunar bases. Sadoway and other MIT researchers explored the idea of sending an electric current through the iron oxide rock on the moon’s surface, using rock from an old asteroid in Arizona for their experiments. The reaction produced oxygen, with metal as a byproduct.The research stuck with Sadoway, who noticed that down here on Earth, that metal byproduct would be of interest. To help make the electrolysis reaction he studied more viable, he joined forces with Allanore, who is a professor of metallurgy at MIT and the Lechtman Chair in the Department of Materials Science and Engineering. The professors were able to identify a less expensive anode and partnered with Yurko, a former student, to found Boston Metal.“All of the fundamental studies and the initial technologies came out of MIT,” Lambotte says. “We spun out of research that was patented at MIT and licensed from MIT’s Technology Licensing Office.”Lambotte joined the company shortly after Boston Metal’s team published a 2013 paper in Nature describing the MOE platform.“That’s when it went from the lab, with a coffee cup-sized experiment to prove the fundamentals and produce a few grams, to a company that can produce hundreds of kilograms, and soon, tons of metal,” Lambotte says.

    Boston Metal’s process takes place in modular MOE cells the size of a school bus. Here is a schematic of the process.

    Boston Metal’s molten oxide electrolysis process takes place in modular MOE cells the size of a school bus. Iron ore rock is fed into the cell, which contains the cathode (the negative terminal of the MOE cell) and an anode immersed in a liquid electrolyte. The anode is inert, meaning it doesn’t dissolve in the electrolyte or take part in the reaction other than serving as the positive terminal. When electricity runs between the anode and cathode and the cell reaches around 1,600 degrees Celsius, the iron oxide bonds in the ore are split, producing pure liquid metal at the bottom that can be tapped. The byproduct of the reaction is oxygen, and the process doesn’t require water, hazardous chemicals, or precious-metal catalysts.The production of each cell depends on the size of its current. Lambotte says with about 600,000 amps, each cell could produce up to 10 tons of metal every day. Steelmakers would license Boston Metal’s technology and deploy as many cells as needed to reach their production targets.Boston Metal is already using MOE to help mining companies recover high-value metals from their mining waste, which usually needs to undergo costly treatment or storage. Lambotte says it could also be used to produce many other kinds of metals down the line, and Boston Metal was recently selected to negotiate grant funding to produce chromium metal — critical for a number of clean energy applications — in West Virginia.“If you look around the world, a lot of the feedstocks for metal are oxides, and if it’s an oxide, then there’s a chance we can work with that feedstock,” Lambotte says. “There’s a lot of excitement because everyone needs a solution capable of decarbonizing the metal industry, so a lot of people are interested to understand where MOE fits in their own processes.”Gigatons of potentialBoston Metal’s steel decarbonization technology is currently slated to reach commercial-scale in 2026, though its Brazil plant is already introducing the industry to MOE.“I think it’s a window for the metal industry to get acquainted with MOE and see how it works,” Lambotte says. “You need people in the industry to grasp this technology. It’s where you form connections and how new technology spreads.”The Brazilian plant runs on 100 percent renewable energy.“We can be the beneficiary of this tremendous worldwide push to decarbonize the energy sector,” Lambotte says. “I think our approach goes hand in hand with that. Fully green steel requires green electricity, and I think what you’ll see is deployment of this technology where [clean electricity] is already readily available.”Boston Metal’s team is excited about MOE’s application across the metals industry but is focused first and foremost on eliminating the gigatons of emissions from steel production.“Steel produces around 10 percent of global emissions, so that is our north star,” Lambotte says. “Everyone is pledging carbon reductions, emissions reductions, and making net zero goals, so the steel industry is really looking hard for viable technology solutions. People are ready for new approaches.” More