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    Celebrating the people behind Kendall Square’s innovation ecosystem

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    While it’s easy to be amazed by the constant drumbeat of innovations coming from Kendall Square in Cambridge, Massachusetts, sometimes overlooked are the dedicated individuals working to make those scientific and technological breakthroughs a reality. Every day, people in the neighborhood tackle previously intractable problems and push the frontiers of their fields.This year’s Kendall Square Association (KSA) Annual Meeting centered around celebrating the people behind the area’s prolific innovation ecosystem. That included a new slate of awards and recognitions for community members and a panel discussion featuring MIT President Sally Kornbluth.“It’s truly inspiring to be surrounded by all of you: people who seem to share an exuberant curiosity, a pervasive ethic of service, and the baseline expectation that we’re all interested in impact — in making a difference for people and the planet,” Kornbluth said.The gathering took place in MIT’s Walker Memorial (Building 50) on Memorial Drive and attracted entrepreneurs, life science workers, local students, restaurant and retail shop owners, and leaders of nonprofits.The KSA itself is a nonprofit organization made up of over 150 organizations across the greater Kendall Square region, from large companies to universities like MIT and Harvard, along with the independent shops and restaurants that give Kendall Square its distinct character.New to this year’s event were two Founder Awards, which were given to Sangeeta Bhatia, the the John and Dorothy Wilson Professor of Health Sciences and Technology and of Electrical Engineering and Computer Science at MIT, and Michal Preminger, head of Johnson and Johnson Innovation, for their work bringing people together to achieve hard things that benefit humanity.The KSA will donate $2,500 to the Science Club for Girls in Bhatia’s honor and $2,500 to Innovators for Purpose in honor of Preminger.Recognition was also given to Alex Cheung of the Cambridge Innovation Center and Shazia Mir of LabCentral for their work bringing Kendall Square’s community members together.Cambridge Mayor Denise Simmons also spoke at the event, noting the vital role the Kendall Square community has played in things like Covid-19 vaccine development and in the fight against climate change.“As many of you know, Cambridge has a long and proud history of innovation, with the presence of MIT and the remarkable growth of the tech and life science industry examples of that,” Simmons said. “We are leaving a lasting, positive impact in our city. This community has made and continues to make enormous contributions, not just to our city but to the world.”In her talk, Kornbluth also introduced the Kendall Square community to her plans for The Climate Project at MIT, which is designed to focus the Institute’s talent and resources to achieve real-world impact on climate change faster. The project will provide funding and catalyze partnerships around six climate “missions,” or broad areas where MIT researchers will seek to identify gaps in the global climate response that MIT can help fill.“The Climate Project is a whole-of-MIT mobilization that’s mission driven, solution focused, and outward looking,” Kornbluth explained. “If you want to make progress, faster and at scale, that’s the way!”After mingling with Kendall community members, Kornbluth said she still considers herself a newbie to the area but is coming to see the success of Kendall Square and MIT as more than a coincidence.“The more time I spend here, the more I come to understand the incredible synergies between MIT and Kendall Square,” Kornbluth said. “We know, for example, that proximity is an essential ingredient in our collective and distinctive recipe for impact. That proximity, and the cross-fertilization that comes with it, helps us churn out new technologies and patents, found startups, and course-correct our work as we try to keep pace with the world’s challenges. We can’t do any of this separately. Our work together — all of us in this thriving, wildly entrepreneurial community — is what drives the success of our innovation ecosystem.” More

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      in Environment

      Tracking emissions to help companies reduce their environmental footprint

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      Amidst a global wave of corporate pledges to decarbonize or reach net-zero emissions, a system for verifying actual greenhouse gas reductions has never been more important. Context Labs, founded by former MIT Sloan Fellow and serial entrepreneur Dan Harple SM ’13, is rising to meet that challenge with an analytics platform that brings more transparency to emissions data.The company’s platform adds context to data from sources like equipment sensors and satellites, provides third-party verification, and records all that information on a blockchain. Context Labs also provides an interactive view of emissions across every aspect of a company’s operations, allowing leaders to pinpoint the dirtiest parts of their business.“There’s an old adage: Unless you measure something, you can’t change it,” says Harple, who is the firm’s CEO. “I think of what we’re doing as an AI-driven digital lens into what’s happening across organizations. Our goal is to help the planet get better, faster.”Context Labs is already working with some of the largest energy companies in the world — including EQT, Williams Companies, and Coterra Energy — to verify emissions reductions. A partnership with Microsoft, announced at last year’s COP28 United Nations climate summit, allows any organization on Microsoft’s Azure cloud to integrate their sensor data into Context Lab’s platform to get a granular view of their environmental impact.Harple says the progress enables more informed sustainability initiatives at scale. He also sees the work as a way to combat overly vague statements about sustainable practices that don’t lead to actual emissions reductions, or what’s known as “greenwashing.”“Just producing data isn’t good enough, and our customers realize that, because they know even if they have good intentions to reduce emissions, no one is going to believe them,” Harple says. “One way to think about our platform is as antigreenwashing insurance, because if you get attacked for your emissions, we unbundle the data like it’s in shrink-wrap and roll it back through time on the blockchain. You can click on it and see exactly where and how it was measured, monitored, timestamped, its serial number, everything. It’s really the gold standard of proof.”An unconventional master’sHarple came to MIT as a serial founder whose companies had pioneered several foundational internet technologies, including real-time video streaming technology still used in applications like Zoom and Netflix, as well as some of the core technology for the popular Chinese microblogging website Weibo.Harple’s introduction to MIT started with a paper he wrote for his venture capital contacts in the U.S. to make the case for investment in the Netherlands, where he was living with his family. The paper caught the attention of MIT Professor Stuart Madnick, the John Norris Maguire Professor of Information Technology at the MIT Sloan School of Management, who suggested Harple come to MIT as a Sloan Fellow to further develop his ideas about what makes a strong innovation ecosystem.Having successfully founded and exited multiple companies, Harple was not a typical MIT student when he began the Sloan Fellows program in 2011. At one point, he held a summit at MIT for a group of leading Dutch entrepreneurs and government officials that included tours of major labs and a meeting with former MIT President L. Rafael Reif.“Everyone was super enamored with MIT, and that kicked off what became a course that I started at MIT called REAL, Regional Entrepreneurial Acceleration Lab,” Harple says. REAL was eventually absorbed by what is now REAP — the Regional Entrepreneurship Acceleration Program, which has worked with communities around the world.Harple describes REAL as a framework vehicle to put his theories on supporting innovation into action. Over his time at MIT, which also included collaborating with the Media Lab, he systematized those theories into what he calls pentalytics, which is a way to measure and predict the resilience of innovation ecosystems.“My sense was MIT should be analytical and data-driven,” Harple says. “The thesis I wrote was a framework for AI-driven network graph analytics. So, you can model things using analytics, and you can use AI to do predictive analytics to see where the innovation ecosystem is going to thrive.”Once Harple’s pentalytics theory was established, he wanted to put it to the test with a company. His initial idea for Context Labs was to build a verification platform to combat fake news, deepfakes, and other misinformation on the internet. Around 2018, Harple met climate investor Jeremy Grantham, who he says helped him realize the most important data are about the planet. Harple began to believe that U.S. Environmental Protection Agency (EPA) emissions estimates for things like driving a car or operating an oil rig were just that — estimates — and left room for improvement.“Our approach was very MIT-ish,” Harple says. “We said, ‘Let’s, measure it and let’s monitor it, and then let’s contextualize that data so you can never go back and say they faked it. I think there’s a lot of fakery that’s happened, and that’s why the voluntary carbon markets cratered in the last year. Our view is they cratered because the data wasn’t empirical enough.”Context Labs’ solution starts with a technology platform it calls Immutably that continuously combines disparate data streams, encrypts that information, and records it on a blockchain. Immutably also verifies the information with one or more third parties. (Context Labs has partnered with the global accounting firm KPMG.)On top of Immutably, Context Labs has built applications, including a product called Decarbonization-as-a-Service (DaaS), which uses Immutably’s data to give companies a digital twin of their entire operations. Customers can use DaaS to explore the emissions of their assets and create a certificate of verified CO2-equivalent emissions, which can be used in carbon credit markets.Putting emissions data into contextContext Labs is working with oil and gas companies, utilities, data centers, and large industrial operators, some using the platform to analyze more than 3 billion data points each day. For instance, EQT, the largest natural gas producer in the U.S., uses Context Labs to verify its lower-emission products and create carbon credits. Other customers include the nonprofits Rocky Mountain Institute and the Environmental Defense Fund.“I often get asked how big the total addressable market is,” Harple says. “My view is it’s the largest market in history. Why? Because every country needs a decarbonization plan, along with instrumentation and a digital platform to execute, as does every company.”With its headquarters in Kendall Square in Cambridge, Massachusetts, Context Labs is also serving as a test for Harple’s pentalytics theory for innovation ecosystems. It also has operations in Houston and Amsterdam.“This company is a living lab for pentalytics,” Harple says. “I believe Kendall Square 1.0 was factory buildings, Kendall Square 2.0 is biotech, and Kendall Square 3.0 will be climate tech.” More

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      in Environment

      A home where world-changing innovations take flight

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      In a large, open space on the first floor of 750 Main Street in Cambridge, Massachusetts, a carbon-capture company is heating up molten salts to 600 degrees Celsius right next to a quantum computing company’s device for supercooling qubits. The difference is about 900 degrees across 15 feet.

      It doesn’t take long in the tour of The Engine Accelerator to realize this isn’t your typical co-working space. Companies here are working at the extremes to develop new technologies with world-changing impact — what The Engine Accelerator’s leaders call “tough tech.”

      Comprising four floors and 150,000 square feet next door to MIT’s campus, the new space offers startups specialized lab equipment, advanced machining, fabrication facilities, office space, and a range of startup support services.

      The goal is to give young companies merging science and engineering all of the resources they need to move ideas from the lab bench to their own mass manufacturing lines.

      “The infrastructure has always been a really important accelerant for getting these kinds of companies off and running,” The Engine Accelerator President Emily Knight says. “Now you can start a company and, on day one, start building. Real estate is such a big factor. Our thought was, let’s make this investment in the infrastructure for the founders. It’s an agile lease that enables them to be very flexible as they grow.”

      Since the new facility opened its doors in the summer of 2022, the Accelerator has welcomed around 100 companies that employ close to 1,000 people. In addition to the space, members enjoy educational workshops on topics like fundraising and hiring, events, and networking opportunities that the Accelerator team hopes foster a sense of community among people working in the tough tech space overall.

      “We’re not just advocates for the startups in the space,” Knight says. “We’re advocates for tough tech as a whole. We think it’s important for the state of Massachusetts to create a tough tech hub here, and we think it’s important for national competitiveness.”

      Tough tech gets a home

      The Engine was spun out of MIT in 2016 as a public benefit corporation with the mission of bridging the gap between discovery and commercialization. Since its inception, it has featured an investment component, now known as Engine Ventures, and a shared services component.

      From the moment The Engine opened its doors to startups in its original headquarters on Massachusetts Avenue in Cambridge, the services team got a firsthand look at the unique challenges faced by tough tech startups. After speaking with founders, they realized their converted office space would need more power, stronger floors, and full lab accommodations.

      The team rose to the challenge. They turned a closet into a bio lab. They turned an unused wellness room into a laser lab. They managed to accommodate Commonwealth Fusion Systems when the founders informed them a 5,000-pound magnet would soon arrive for testing.

      But supporting ambitious founders in their quest to build world-changing companies was always going to require a bigger boat. As early as 2017, MIT’s leaders were considering turning the old Polaroid building, which had sat empty next to MIT’s campus for nearly 20 years, into the new home for tough tech.

      Speaking of tough, construction crews began the extensive building renovations for the Accelerator at the end of 2019, a few months before the Covid-19 pandemic. The team managed to avoid the worst of the supply chain disruptions, but they quickly learned the building has its quirks. Each floor is a different ceiling height, and massive pillars known as mushroom columns punctuate each floor.

      Based on conversations with founders, The Engine’s Accelerator team outfitted the renovated building with office and co-working space, a full machine shop, labs for biology and chemistry work, an array of 3D printers, bike storage, and, perhaps most important, cold brew on tap.

      “I think of the Accelerator as a really great Airbnb host rather than a landlord, where maybe you rented a bedroom in a large house, but you feel like you rented the whole thing because you have access to all kinds of amazing equipment,” says Bernardo Cervantes PhD ’20, co-founder of Concerto Biosciences, which is developing microbes for a variety of uses in human health and agriculture.

      The Engine Accelerator’s team credits MIT leadership with helping them manage the project, noting that the MIT Environment, Health and Safety office was particularly helpful.

      A week after the Accelerator opened its doors in August 2022, on a single sweltering day, 35 companies moved in. By 2023, the Accelerator was home to 55 companies. Since then, the Accelerator’s team has done everything they could to continue to grow.

      “At one point, one of our team members came to me with her tail between her legs and sheepishly said, ‘I gave our office space to a startup,’” Knight recalls. “I said, ‘Yes! That means you get it! We don’t need an office — we can sit anywhere.’”

      The first floor holds some of the largest machinery, including that molten salt device (developed by Mantel Capture) and the quantum computer (developed by Atlantic Quantum). On the next level, a machine shop and a fabrication space featuring every 3D printer imaginable offer ways for companies to quickly build prototype products or parts. Another floor is dubbed “the Avenue” and features a kitchen and tables for networking and serendipitous meetings. The Avenue is lined by huge garage doors that open to accommodate larger crowds for workshops and meeting spaces.

      “Even though the founders are working in different spaces, we wanted to create an area where people can connect and run into each other and get help with 3D printing or hiring or anything else,” Knight says. “It fosters those casual interactions that are very important for startups.”

      An ecosystem to change the world

      Only about one-fifth of the companies in the Accelerator space are portfolio companies of Engine Ventures. The two entities operate separately, but they pool their shared learning about supporting tough tech, and Engine Ventures has an office in the Accelerator’s space.

      Engine Ventures CEO Katie Rae sees it as a symbiotic partnership.

      “We needed to have all these robust services for everyone in tough tech, not just the portfolio companies,” Rae says. “We’ll always work together and produce the Tough Tech Summit together because of our overarching missions. It’s very much like a rising tide lifts all boats. All of these companies are working to change the world in their own verticals, so we’re just focusing on the impact they’re trying to have and making that the story.”

      Rae says MIT has helped both of The Engine’s teams think through the best way to support tough tech startups.

      “Being a partner with MIT, which understands innovation and safety better than anyone, has allowed us to say yes to more things and have more flexibility,” Rae says. “If you’re going to go at breakneck speed to solve global problems, you better have a mentality of getting things done fast and safely, and I think that’s been a core tenet of The Engine.”

      Meanwhile, Knight says her team hasn’t stopped learning from the tough tech community and will continue to adapt.

      “There’s just a waterfall of information coming from these companies,” Knight says. “It’s about iterating on our services to best support them, so we can go to people on our team and ask, ‘Can you learn to run this type of program, because we just learned these five founders need it?’ Every founder we know in the area has a badge so they can come in. We want to create a hub for tough tech within this Kendall Square area that’s already a hub in so many ways.” More

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      in Environment

      MIT campus goals in food, water, waste support decarbonization efforts

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      With the launch of Fast Forward: MIT’s Climate Action Plan for the Decade, the Institute committed to decarbonize campus operations by 2050 — an effort that touches on every corner of MIT, from building energy use to procurement and waste. At the operational level, the plan called for establishing a set of quantitative climate impact goals in the areas of food, water, and waste to inform the campus decarbonization roadmap. After an 18-month process that engaged staff, faculty, and researchers, the goals — as well as high-level strategies to reach them — were finalized in spring 2023.

      The goal development process was managed by a team representing the areas of campus food, water, and waste, respectively, and includes Director of Campus Dining Mark Hayes and Senior Sustainability Project Manager Susy Jones (food), Director of Utilities Janine Helwig (water), Assistant Director of Campus Services Marty O’Brien, and Assistant Director of Sustainability Brain Goldberg (waste) to co-lead the efforts. The group worked together to set goals that leverage ongoing campus sustainability efforts. “It was important for us to collaborate in order to identify the strategies and goals,” explains Goldberg. “It allowed us to set goals that not only align, but build off of one another, enabling us to work more strategically.”

      In setting the goals, each team relied on data, community insight, and best practices. The co-leads are sharing their process to help others at the Institute understand the roles they can play in supporting these objectives.  

      Sustainable food systems

      The primary food impact goal aims for a 25 percent overall reduction in the greenhouse gas footprint of food purchases starting with academic year 2021-22 as a baseline, acknowledging that beef purchases make up a significant share of those emissions. Additionally, the co-leads established a goal to recover all edible food waste in dining hall and retail operations where feasible, as that reduces MIT’s waste impact and acknowledges that redistributing surplus food to feed people is critically important.

      The work to develop the food goal was uniquely challenging, as MIT works with nine different vendors — including main vendor Bon Appetit — to provide food on campus, with many vendors having their own sustainability targets. The goal-setting process began by understanding vendor strategies and leveraging their climate commitments. “A lot of this work is not about reinventing the wheel, but about gathering data,” says Hayes. “We are trying to connect the dots of what is currently happening on campus and to better understand food consumption and waste, ensuring that we area reaching these targets.”

      In identifying ways to reach and exceed these targets, Jones conducted listening sessions around campus, balancing input with industry trends, best-available science, and institutional insight from Hayes. “Before we set these goals and possible strategies, we wanted to get a grounding from the community and understand what would work on our campus,” says Jones, who recently began a joint role that bridges the Office of Sustainability and MIT Dining in part to support the goal work.

      By establishing the 25 percent reduction in the greenhouse gas footprint of food purchases across MIT residential dining menus, Jones and Hayes saw goal-setting as an opportunity to add more sustainable, local, and culturally diverse foods to the menu. “If beef is the most carbon-intensive food on the menu, this enables us to explore and expand so many recipes and menus from around the globe that incorporate alternatives,” Jones says.

      Strategies to reach the climate food goals focus on local suppliers, more plant-forward meals, food recovery, and food security. In 2019, MIT was a co-recipient of the New England Food Vision Prize provided by the Kendall Foundation to increase the amount of local food served on campus in partnership with CommonWealth Kitchen in Dorchester. While implementation of that program was put on pause due to the pandemic, work resumed this year. Currently, the prize is funding a collaborative effort to introduce falafel-like, locally manufactured fritters made from Maine-grown yellow field peas to dining halls at MIT and other university campuses, exemplifying the efforts to meet the climate impact goal, serve as a model for others, and provide demonstrable ways of strengthening the regional food system.

      “This sort of innovation is where we’re a leader,” says Hayes. “In addition to the Kendall Prize, we are looking to focus on food justice, growing our BIPOC [Black, Indigenous, and people of color] vendors, and exploring ideas such as local hydroponic and container vegetable growing companies, and how to scale these types of products into institutional settings.”

      Reduce and reuse for campus water

      The 2030 water impact goal aims to achieve a 10 percent reduction in water use compared to the 2019 baseline and to update the water reduction goal to align with the new metering program and proposed campus decarbonization plans as they evolve.

      When people think of campus water use, they may think of sprinklers, lab sinks, or personal use like drinking water and showers. And while those uses make up around 60 percent of campus water use, the Central Utilities Plant (CUP) accounts for the remaining 40 percent. “The CUP generates electricity and delivers heating and cooling to the campus through steam and chilled water — all using what amounts to a large percentage of water use on campus,” says Helwig. As such, the water goal focuses as much on reuse as reduction, with one approach being to expand water capture from campus cooling towers for reuse in CUP operations. “People often think of water use and energy separately, but they often go hand-in-hand,” Helwig explains.

      Data also play a central part in the water impact goal — that’s why a new metering program is called for in the implementation strategy. “We have access to a lot of data at MIT, but in reviewing the water data to inform the goal, we learned that it wasn’t quite where we needed it,” explains Helwig. “By ensuring we have the right meter and submeters set up, we can better set boundaries to understand where there is the potential to reduce water use.” Irrigation on campus is one such target with plans to soon release new campuswide landscaping standards that minimize water use.

      Reducing campus waste

      The waste impact goal aims to reduce campus trash by 30 percent compared to 2019 baseline totals. Additionally, the goal outlines efforts to improve the accuracy of indicators tracking campus waste; reduce the percentage of food scraps in trash and percent of recycling in trash in select locations; reduce the percentage of trash and recycling comprised of single use items; and increase the percentage of residence halls and other campus spaces where food is consumed at scale, implementing an MIT food scrap collection program.

      In setting the waste goals, Goldberg and O’Brien studied available campus waste data from past waste audits, pilot programs, and MIT’s waste haulers. They factored in state and city policies that regulate things like the type and amount of waste large institutions can transport. “Looking at all the data it became clear that a 30 percent trash reduction goal will make a tremendous impact on campus and help us drive toward the goal of completely designing out waste from campus,” Goldberg says. The strategies to reach the goals include reducing the amount of materials that come into campus, increasing recycling rates, and expanding food waste collection on campus.

      While reducing the waste created from material sources is outlined in the goals, food waste is a special focus on campus because it comprises approximately 40 percent of campus trash, it can be easily collected separately from trash and recycled locally, and decomposing food waste is one of the largest sources of greenhouse gas emissions found in landfills. “There is a lot of greenhouse gas emissions that result from production, distribution, transportation, packaging, processing, and disposal of food,” explains Goldberg. “When food travels to campus, is removed from campus as waste, and then breaks down in a landfill, there are emissions every step of the way.”

      To reduce food waste, Goldberg and O’Brien outlined strategies that include working with campus suppliers to identify ordering volumes and practices to limit waste. Once materials are on campus, another strategy kicks in, with a new third stream of waste collection that joins recycling and trash — food waste. By collecting the food waste separately — in bins that are currently rolling out across campus — the waste can be reprocessed into fertilizer, compost, and/or energy without the off-product of greenhouse gases. The waste impact goal also relies on behavioral changes to reduce waste, with education materials part of the process to reduce waste and decontaminate reprocessing streams.

      Tracking progress

      As work toward the goals advances, community members can monitor progress in the Sustainability DataPool Material Matters and Campus Water Use dashboards, or explore the Impact Goals in depth.

      “From food to water to waste, everyone on campus interacts with these systems and can grapple with their impact either from a material they need to dispose of, to water they’re using in a lab, or leftover food from an event,” says Goldberg. “By setting these goals we as an institution can lead the way and help our campus community understand how they can play a role, plug in, and make an impact.” More

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      in Energy

      Celebrating Kendall Square’s past and shaping its future

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      Kendall Square’s community took a deep dive into the history and future of the region at the Kendall Square Association’s 15th annual meeting on Oct. 19.

      It’s no secret that Kendall Square, located in Cambridge, Massachusetts, moves fast. The event, titled “Looking Back, Looking Ahead,” gave community members a chance to pause and reflect on how far the region has come and to discuss efforts to shape where it’s going next.

      “The impact of the last 15 years of working together with a purposeful commitment to make the world a better place was on display this evening,” KSA Executive Director Beth O’Neill Maloney told the audience toward the end of the evening. “It also shows how Kendall Square can continue contributing to the world.”

      The gathering took place at the Microsoft NERD Center on Memorial Drive, on a floor that also featured music from the Kendall Square Orchestra and, judging by the piles of empty trays at the end of the night, an exceedingly popular selection of food from Kendall Square restaurants. Attendees came from across Cambridge’s prolific innovation ecosystem — not just entrepreneurs and life science workers but also high school and college students, restaurant and retail shop owners, workers at local cleantech and robotics companies, and leaders of nonprofits.

      KSA itself is a nonprofit made up of over 150 organizations across Kendall Square, from major companies to universities like MIT to research organizations like the Broad Institute of MIT and Harvard and the independent shops and restaurants that give Kendall Square its distinct character.

      The night’s programming included talks about recent funding achievements in the region, a panel discussion on the implications of artificial intelligence, and a highly entertaining, whirlwind history lesson led by Daniel Berger-Jones of Cambridge Historical Tours.

      “Our vision for the state is to be the best, and Kendall really represents that,” said Yvonne Hao, Massachusetts secretary of economic development. “When I went to DC to talk to folks about why Massachusetts should win some of these grants, they said, ‘You already have Kendall, that’s what we’re trying to get the whole country to be like!’”

      Hao started her talk by noting her personal connection to Kendall Square. She moved to Cambridge with her family in 2010 and has watched the neighborhood transform, with her kids frequenting the old and new restaurants and shops around town.

      The crux of Hao’s talk was to remind attendees they had more to celebrate than KSA’s anniversary. Massachusetts was recently named the recipient of two major federal grants that will fuel the state’s innovation work. One of those grants, from the Advanced Research Projects Agency for Health (ARPA-H), designated the state an “Investor Catalyst Hub” to accelerate innovation around health care. The other, which came through the federal CHIPS and Science Act, will allow the state to establish the Northeast Microelectronics Coalition Hub to advance microelectronics jobs, workforce training opportunities, and investment in the region’s advanced manufacturing.

      Hao recalled making the pitch for the grants, which could collectively amount to hundreds of millions of dollars in funding over time.

      “The pitch happened in Kendall Square because Kendall highlights everything magical about Massachusetts — we have our universities, MIT, we have our research institutions, nonprofits, small businesses, and great community members,” Hao said. “We were hoping for good weather because we wanted to walk with government officials, because when you walk around Kendall, you see the art, you see the coffee shops, you see the people bumping into each other and talking, and you see why it’s so important that this one square mile of geography become the hub they were looking for.”

      Hao is also part of work to put together the state’s newest economic development plan. She said the group’s tier one priorities are transportation and housing, but listed a number of other areas where she hopes Massachusetts can improve.

      “We can be an amazing, strong economy that’s mission-driven and innovation-driven with all kinds of jobs for all kinds of people, and at the same time an awesome community that loves each other and has great food and small businesses and looks out for each other, that looks diverse just like this room,” Hao said. “That’s the story we want to tell.”

      After the historical tour and the debut of a video explaining the origins of the KSA, attendees fast-forwarded into the future with a panel discussion on the impact and implications of generative AI.

      “I think the paradigm shift we’re seeing with generative AI is going to be as transformative as the internet, perhaps even more so because the pace of adoption is much faster now,” said Microsoft’s Soundar Srinivasan.

      The panel also featured Jennat Jounaidi, a student at Cambridge Rindge and Latin School and member of Innovators for Purpose, a nonprofit that seeks to empower young people from historically marginalized groups to become innovators.

      “I’m interested to see how generative AI shapes my upbringing as well as the lives of future generations, and I think it’s a pivotal moment to decide how we can best develop and incorporate AI into all of our lives,” Jounaidi said.

      Panelists noted that today’s concerns around AI are important, such as its potential to perpetuate inequality and amplify misinformation. But they also discussed the technology’s potential to drive advances in areas like sustainability and health care.

      “I came to Kendall Square to do my PhD in AI at MIT back when the internet was called the ARPA-Net… so a while ago,” said Jeremy Wertheimer SM ’89, PhD ’96. “One of the dreams I had back then was to create a program to read all biology papers. We’re not quite there yet, but I think we’re on the cusp, and it’s very exciting.

      Above all else, the panelists characterized AI as an opportunity. Despite all that’s been accomplished in Kendall Square to date, the prevailing feeling at the event was excitement for the future.

      “Generative AI is giving us chance to stop working in siloes,” Jounaidi said. “Many people in this room go back to their companies and think about corporate responsibility, and I want to expand that to creating shared value in companies by seeking out the community and the people here. I think that’s important, and I’m excited to see what comes next.” More

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      in Energy

      Doubling down on sustainability innovation in Kendall Square

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      From its new headquarters in Cambridge’s Kendall Square, The Engine is investing in a number of “tough tech” startups seeking to transform the world’s energy systems. A few blocks away, the startup Inari is using gene editing to improve seeds’ resilience to climate change. On the MIT campus nearby, researchers are working on groundbreaking innovations to meet the urgent challenges our planet faces.

      Kendall Square is known as the biotech capital of the world, but as the latest annual meeting of the Kendal Square Association (KSA) made clear, it’s also a thriving hub of sustainability-related innovation.

      The Oct. 20 event, which began at MIT’s Welcome Center before moving to the MIT Museum for a panel discussion, brought together professionals from across Cambridge’s prolific innovation ecosystem — not just entrepreneurs working at startups, but also students, restaurant and retail shop owners, and people from local nonprofits.

      Titled “[Re] Imagining a Sustainable Future,” the meeting highlighted advances in climate change technologies that are afoot in Kendall Square, to help inspire and connect the community as it works toward common sustainability goals.

      “Our focus is on building a better future together — and together is the most important word there,” KSA Executive Director Beth O’Neill Maloney said in her opening remarks. “This is an incredibly innovative ecosystem and community that’s making changes that affect us here in Kendall Square and far, far beyond.”

      The pace of change

      The main event of the evening was a panel discussion moderated by Lee McGuire, the chief communications officer of the Broad Institute of MIT and Harvard. The panel featured Stuart Brown, chief financial officer at Inari; Emily Knight, chief operating officer at The Engine; and Joe Higgins, vice president for campus services and stewardship at MIT.

      “Sustainability is obviously one of the most important — if not the most important — challenge facing us as a society today,” said McGuire, opening the discussion. “Kendall Square is known for its work in biotech, life sciences, AI, and climate, and the more we dug into it the more we realized how interconnected all of those things are. The talent in Kendall Square wants to work on problems relevant for humanity, and the tools and skills you need for that can be very similar depending on the problem you’re working on.”

      Higgins, who oversees the creation of programs to reduce MIT’s environmental impact and improve the resilience of campus operations, focused on the enormity of the problem humanity is facing. He showed the audience a map of the U.S. power grid, with power plants and transmission lines illuminated in a complex web across the country, to underscore the scale of electrification that will be needed to mitigate the worst effects of climate change.

      “The U.S. power grid is the largest machine ever made by mankind,” Higgins said. “It’s been developed over 100 years; it has 7,000 generating plants that feed into it every day; it has 7 million miles of cable and wires; there are transformers and substations; and it lives in every single one of your walls. But people don’t think about it that much.”

      Many cities, states, and organizations like MIT have made commitments to shift to 100 percent clean energy in coming decades. Higgins wanted the audience to try to grasp what that’s going to take.

      “Hundreds of millions of devices and equipment across the planet are going to have to be swapped from fossil fuel to electric-based,” Higgins said. “Our cars, appliances, processes in industry, like making steel and concrete, are going to need to come from this grid. It’ll need to undergo a major modernization and transformation. The good news is it’s already changing.”

      Multiple panelists pointed to developments like the passing of the Inflation Reduction Act to show there was progress being made in reaching urgent sustainability goals.

      “There is a tide change coming, and it’s not only being driven by private capital,” Knight said. “There’s a huge opportunity here, and it’s a really important part of this [Kendall Square] ecosystem.”

      Chief among the topics of discussion was technology development. Even as leaders implement today’s technologies to decarbonize, people in Kendall Square keep a close eye on the new tech being developed and commercialized nearby.

      “I was trying to think about where we are with gene editing,” Brown said. “CRISPR’s been around for 10 years. Compare that to video games. Pong was the first video game when it came out in 1972. Today you have Chess.com using artificial intelligence to power chess games. On gene editing and a lot of these other technologies, we’re much closer to Pong than we are to where it’s going to be. We just can’t imagine today the technology changes we’re going to see over the next five to 10 years.”

      In that regard, Knight discussed some of the promising portfolio companies of The Engine, which invests in early stage, technologically innovative companies. In particular, she highlighted two companies seeking to transform the world’s energy systems with entirely new, 100 percent clean energy sources. MIT spinout Commonwealth Fusion Systems is working on nuclear fusion reactors that could provide abundant, safe, and constant streams of clean energy to our grids, while fellow MIT spinout Quaise Energy is seeking to harvest a new kind of deep geothermal energy using millimeter wave drilling technology.

      “All of our portfolio companies have a focus on sustainability in one way or another,” Knight said. “People who are working on these very hard technologies will change the world.”

      Knight says the kind of collaboration championed by the KSA is important for startups The Engine invests in.

      “We know these companies need a lot of people around them, whether from government, academia, advisors, corporate partners, anyone who can help them on their path, because for a lot of them this is a new path and a new market,” Knight said.

      Reasons for hope

      The KSA is made up of over 150 organizations across Kendall Square. From major employers like Sanofi, Pfizer, MIT, and the Broad Institute to local nonprofit organizations, startups, and independent shops and restaurants, the KSA represents the entire Kendall ecosystem.

      O’Neill Maloney celebrated a visible example of sustainability in Kendall Square early on by the Charles River Conservancy, which has built a floating wetland designed to naturally remove harmful algae blooms from Charles River.

      Other examples of sustainability work in the neighborhood can be found at MIT. Under its “Fast Forward” climate action plan, the Institute has set a goal of eliminating direct emissions from its campus by 2050, including a near-term milestone of achieving net-zero emissions by 2026. Since 2014, when MIT launched a five-year plan for action on climate change, net campus emissions have already been cut by 20 percent by making its campus buildings more energy efficient, transitioning to electric vehicles, and enabling large-scale renewable energy projects, among other strategies.

      In the face of a daunting global challenge, such milestones are reason for optimism.

      “If anybody’s going to be able to do this [shift to 100 percent clean energy] and show how it can be done at an urban, city scale, it’s probably MIT and the city of Cambridge,” McGuire said. “We have a lot of good ingredients to figure this out.”

      Throughout the night, many speakers, attendees, and panelists echoed that sentiment. They said they see plenty of reasons for hope.

      “I’m absolutely optimistic,” Higgins said. “I’m seeing utility companies working with businesses working with regulators — people are coming together on this topic. And one of these new technologies being commercialized is going to change things before 2030, whether its fusion, deep geothermal, small modular nuclear reactors, the technology is just moving so quickly.” More

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      in Environment

      MIT collaborates with Biogen on three-year, $7 million initiative to address climate, health, and equity

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      MIT and Biogen have announced that they will collaborate with the goal to accelerate the science and action on climate change to improve human health. This collaboration is supported by a three-year, $7 million commitment from the company and the Biogen Foundation. The biotechnology company, headquartered in Cambridge, Massachusetts’ Kendall Square, discovers and develops therapies for people living with serious neurological diseases.

      “We have long believed it is imperative for Biogen to make the fight against climate change central to our long-term corporate responsibility commitments. Through this collaboration with MIT, we aim to identify and share innovative climate solutions that will deliver co-benefits for both health and equity,” says Michel Vounatsos, CEO of Biogen. “We are also proud to support the MIT Museum, which promises to make world-class science and education accessible to all, and honor Biogen co-founder Phillip A. Sharp with a dedication inside the museum that recognizes his contributions to its development.”

      Biogen and the Biogen Foundation are supporting research and programs across a range of areas at MIT.

      Advancing climate, health, and equity

      The first such effort involves new work within the MIT Joint Program on the Science and Policy of Global Change to establish a state-of-the-art integrated model of climate and health aimed at identifying targets that deliver climate and health co-benefits.

      “Evidence suggests that not all climate-related actions deliver equal health benefits, yet policymakers, planners, and stakeholders traditionally lack the tools to consider how decisions in one arena impact the other,” says C. Adam Schlosser, deputy director of the MIT Joint Program. “Biogen’s collaboration with the MIT Joint Program — and its support of a new distinguished Biogen Fellow who will develop the new climate/health model — will accelerate our efforts to provide decision-makers with these tools.”

      Biogen is also supporting the MIT Technology and Policy Program’s Research to Policy Engagement Initiative to infuse human health as a key new consideration in decision-making on the best pathways forward to address the global climate crisis, and bridge the knowledge-to-action gap by connecting policymakers, researchers, and diverse stakeholders. As part of this work, Biogen is underwriting a distinguished Biogen Fellow to advance new research on climate, health, and equity.

      “Our work with Biogen has allowed us to make progress on key questions that matter to human health and well-being under climate change,” says Noelle Eckley Selin, who directs the MIT Technology and Policy Program and is a professor in the MIT Institute for Data, Systems, and Society and the Department of Earth, Atmospheric and Planetary Sciences. “Further, their support of the Research to Policy Engagement Initiative helps all of our research become more effective in making change.”

      In addition, Biogen has joined 13 other companies in the MIT Climate and Sustainability Consortium (MCSC), which is supporting faculty and student research and developing impact pathways that present a range of actionable steps that companies can take — within and across industries — to advance progress toward climate targets.

      “Biogen joining the MIT Climate and Sustainability Consortium represents our commitment to working with member companies across a diverse range of industries, an approach that aims to drive changes swift and broad enough to match the scale of the climate challenge,” says Jeremy Gregory, executive director of the MCSC. “We are excited to welcome a member from the biotechnology space and look forward to harnessing Biogen’s perspectives as we continue to collaborate and work together with the MIT community in exciting and meaningful ways.”

      Making world-class science and education available to MIT Museum visitors

      Support from Biogen will honor Nobel laureate, MIT Institute professor, and Biogen co-founder Phillip A. Sharp with a named space inside the new Kendall Square location of the MIT Museum, set to open in spring 2022. Biogen also is supporting one of the museum’s opening exhibitions, “Essential MIT,” with a section focused on solving real-world problems such as climate change. It is also providing programmatic support for the museum’s Life Sciences Maker Engagement Program.

      “Phil has provided fantastic support to the MIT Museum for more than a decade as an advisory board member and now as board chair, and he has been deeply involved in plans for the new museum at Kendall Square,” says John Durant, the Mark R. Epstein (Class of 1963) Director of the museum. “Seeing his name on the wall will be a constant reminder of his key role in this development, as well as a mark of our gratitude.”

      Inspiring and empowering the next generation of scientists

      Biogen funding is also being directed to engage the next generation of scientists through support for the Biogen-MIT Biotech in Action: Virtual Lab, a program designed to foster a love of science among diverse and under-served student populations.

      Biogen’s support is part of its Healthy Climate, Healthy Lives initiative, a $250 million, 20-year commitment to eliminate fossil fuels across its operations and collaborate with renowned institutions to advance the science of climate and health and support under-served communities. Additional support is provided by the Biogen Foundation to further its long-standing focus on providing students with equitable access to outstanding science education. More