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      in Environment

      J-WAFS announces 2023 seed grant recipients

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      Today, the Abdul Latif Jameel Water and Food Systems Lab (J-WAFS) announced its ninth round of seed grants to support innovative research projects at MIT. The grants are designed to fund research efforts that tackle challenges related to water and food for human use, with the ultimate goal of creating meaningful impact as the world population continues to grow and the planet undergoes significant climate and environmental changes.Ten new projects led by 15 researchers from seven different departments will be supported this year. The projects address a range of challenges by employing advanced materials, technology innovations, and new approaches to resource management. The new projects aim to remove harmful chemicals from water sources, develop monitoring and other systems to help manage various aquaculture industries, optimize water purification materials, and more.“The seed grant program is J-WAFS’ flagship grant initiative,” says J-WAFS executive director Renee J. Robins. “The funding is intended to spur groundbreaking MIT research addressing complex issues that are challenging our water and food systems. The 10 projects selected this year show great promise, and we look forward to the progress and accomplishments these talented researchers will make,” she adds.The 2023 J-WAFS seed grant researchers and their projects are:Sara Beery, an assistant professor in the Department of Electrical Engineering and Computer Science (EECS), is building the first completely automated system to estimate the size of salmon populations in the Pacific Northwest (PNW).Salmon are a keystone species in the PNW, feeding human populations for the last 7,500 years at least. However, overfishing, habitat loss, and climate change threaten extinction of salmon populations across the region. Accurate salmon counts during their seasonal migration to their natal river to spawn are essential for fisheries’ regulation and management but are limited by human capacity. Fish population monitoring is a widespread challenge in the United States and worldwide. Beery and her team are working to build a system that will provide a detailed picture of the state of salmon populations in unprecedented, spatial, and temporal resolution by combining sonar sensors and computer vision and machine learning (CVML) techniques. The sonar will capture individual fish as they swim upstream and CVML will train accurate algorithms to interpret the sonar video for detecting, tracking, and counting fish automatically while adapting to changing river conditions and fish densities.Another aquaculture project is being led by Michael Triantafyllou, the Henry L. and Grace Doherty Professor in Ocean Science and Engineering in the Department of Mechanical Engineering, and Robert Vincent, the assistant director at MIT’s Sea Grant Program. They are working with Otto Cordero, an associate professor in the Department of Civil and Environmental Engineering, to control harmful bacteria blooms in aquaculture algae feed production.

      Aquaculture in the United States represents a $1.5 billion industry annually and helps support 1.7 million jobs, yet many American hatcheries are not able to keep up with demand. One barrier to aquaculture production is the high degree of variability in survival rates, most likely caused by a poorly controlled microbiome that leads to bacterial infections and sub-optimal feed efficiency. Triantafyllou, Vincent, and Cordero plan to monitor the microbiome composition of a shellfish hatchery in order to identify possible causing agents of mortality, as well as beneficial microbes. They hope to pair microbe data with detail phenotypic information about the animal population to generate rapid diagnostic tests and explore the potential for microbiome therapies to protect larvae and prevent future outbreaks. The researchers plan to transfer their findings and technology to the local and regional aquaculture community to ensure healthy aquaculture production that will support the expansion of the U.S. aquaculture industry.

      David Des Marais is the Cecil and Ida Green Career Development Professor in the Department of Civil and Environmental Engineering. His 2023 J-WAFS project seeks to understand plant growth responses to elevated carbon dioxide (CO2) in the atmosphere, in the hopes of identifying breeding strategies that maximize crop yield under future CO2 scenarios.Today’s crop plants experience higher atmospheric CO2 than 20 or 30 years ago. Crops such as wheat, oat, barley, and rice typically increase their growth rate and biomass when grown at experimentally elevated atmospheric CO2. This is known as the so-called “CO2 fertilization effect.” However, not all plant species respond to rising atmospheric CO2 with increased growth, and for the ones that do, increased growth doesn’t necessarily correspond to increased crop yield. Using specially built plant growth chambers that can control the concentration of CO2, Des Marais will explore how CO2 availability impacts the development of tillers (branches) in the grass species Brachypodium. He will study how gene expression controls tiller development, and whether this is affected by the growing environment. The tillering response refers to how many branches a plant produces, which sets a limit on how much grain it can yield. Therefore, optimizing the tillering response to elevated CO2 could greatly increase yield. Des Marais will also look at the complete genome sequence of Brachypodium, wheat, oat, and barley to help identify genes relevant for branch growth.Darcy McRose, an assistant professor in the Department of Civil and Environmental Engineering, is researching whether a combination of plant metabolites and soil bacteria can be used to make mineral-associated phosphorus more bioavailable.The nutrient phosphorus is essential for agricultural plant growth, but when added as a fertilizer, phosphorus sticks to the surface of soil minerals, decreasing bioavailability, limiting plant growth, and accumulating residual phosphorus. Heavily fertilized agricultural soils often harbor large reservoirs of this type of mineral-associated “legacy” phosphorus. Redox transformations are one chemical process that can liberate mineral-associated phosphorus. However, this needs to be carefully controlled, as overly mobile phosphorus can lead to runoff and pollution of natural waters. Ideally, phosphorus would be made bioavailable when plants need it and immobile when they don’t. Many plants make small metabolites called coumarins that might be able to solubilize mineral-adsorbed phosphorus and be activated and inactivated under different conditions. McRose will use laboratory experiments to determine whether a combination of plant metabolites and soil bacteria can be used as a highly efficient and tunable system for phosphorus solubilization. She also aims to develop an imaging platform to investigate exchanges of phosphorus between plants and soil microbes.Many of the 2023 seed grants will support innovative technologies to monitor, quantify, and remediate various kinds of pollutants found in water. Two of the new projects address the problem of per- and polyfluoroalkyl substances (PFAS), human-made chemicals that have recently emerged as a global health threat. Known as “forever chemicals,” PFAS are used in many manufacturing processes. These chemicals are known to cause significant health issues including cancer, and they have become pervasive in soil, dust, air, groundwater, and drinking water. Unfortunately, the physical and chemical properties of PFAS render them difficult to detect and remove.Aristide Gumyusenge, the Merton C. Assistant Professor of Materials Science and Engineering, is using metal-organic frameworks for low-cost sensing and capture of PFAS. Most metal-organic frameworks (MOFs) are synthesized as particles, which complicates their high accuracy sensing performance due to defects such as intergranular boundaries. Thin, film-based electronic devices could enable the use of MOFs for many applications, especially chemical sensing. Gumyusenge’s project aims to design test kits based on two-dimensional conductive MOF films for detecting PFAS in drinking water. In early demonstrations, Gumyusenge and his team showed that these MOF films can sense PFAS at low concentrations. They will continue to iterate using a computation-guided approach to tune sensitivity and selectivity of the kits with the goal of deploying them in real-world scenarios.Carlos Portela, the Brit (1961) and Alex (1949) d’Arbeloff Career Development Professor in the Department of Mechanical Engineering, and Ariel Furst, the Cook Career Development Professor in the Department of Chemical Engineering, are building novel architected materials to act as filters for the removal of PFAS from water. Portela and Furst will design and fabricate nanoscale materials that use activated carbon and porous polymers to create a physical adsorption system. They will engineer the materials to have tunable porosities and morphologies that can maximize interactions between contaminated water and functionalized surfaces, while providing a mechanically robust system.Rohit Karnik is a Tata Professor and interim co-department head of the Department of Mechanical Engineering. He is working on another technology, his based on microbead sensors, to rapidly measure and monitor trace contaminants in water.Water pollution from both biological and chemical contaminants contributes to an estimated 1.36 million deaths annually. Chemical contaminants include pesticides and herbicides, heavy metals like lead, and compounds used in manufacturing. These emerging contaminants can be found throughout the environment, including in water supplies. The Environmental Protection Agency (EPA) in the United States sets recommended water quality standards, but states are responsible for developing their own monitoring criteria and systems, which must be approved by the EPA every three years. However, the availability of data on regulated chemicals and on candidate pollutants is limited by current testing methods that are either insensitive or expensive and laboratory-based, requiring trained scientists and technicians. Karnik’s project proposes a simple, self-contained, portable system for monitoring trace and emerging pollutants in water, making it suitable for field studies. The concept is based on multiplexed microbead-based sensors that use thermal or gravitational actuation to generate a signal. His proposed sandwich assay, a testing format that is appealing for environmental sensing, will enable both single-use and continuous monitoring. The hope is that the bead-based assays will increase the ease and reach of detecting and quantifying trace contaminants in water for both personal and industrial scale applications.Alexander Radosevich, a professor in the Department of Chemistry, and Timothy Swager, the John D. MacArthur Professor of Chemistry, are teaming up to create rapid, cost-effective, and reliable techniques for on-site arsenic detection in water.Arsenic contamination of groundwater is a problem that affects as many as 500 million people worldwide. Arsenic poisoning can lead to a range of severe health problems from cancer to cardiovascular and neurological impacts. Both the EPA and the World Health Organization have established that 10 parts per billion is a practical threshold for arsenic in drinking water, but measuring arsenic in water at such low levels is challenging, especially in resource-limited environments where access to sensitive laboratory equipment may not be readily accessible. Radosevich and Swager plan to develop reaction-based chemical sensors that bind and extract electrons from aqueous arsenic. In this way, they will exploit the inherent reactivity of aqueous arsenic to selectively detect and quantify it. This work will establish the chemical basis for a new method of detecting trace arsenic in drinking water.Rajeev Ram is a professor in the Department of Electrical Engineering and Computer Science. His J-WAFS research will advance a robust technology for monitoring nitrogen-containing pollutants, which threaten over 15,000 bodies of water in the United States alone.Nitrogen in the form of nitrate, nitrite, ammonia, and urea can run off from agricultural fertilizer and lead to harmful algal blooms that jeopardize human health. Unfortunately, monitoring these contaminants in the environment is challenging, as sensors are difficult to maintain and expensive to deploy. Ram and his students will work to establish limits of detection for nitrate, nitrite, ammonia, and urea in environmental, industrial, and agricultural samples using swept-source Raman spectroscopy. Swept-source Raman spectroscopy is a method of detecting the presence of a chemical by using a tunable, single mode laser that illuminates a sample. This method does not require costly, high-power lasers or a spectrometer. Ram will then develop and demonstrate a portable system that is capable of achieving chemical specificity in complex, natural environments. Data generated by such a system should help regulate polluters and guide remediation.Kripa Varanasi, a professor in the Department of Mechanical Engineering, and Angela Belcher, the James Mason Crafts Professor and head of the Department of Biological Engineering, will join forces to develop an affordable water disinfection technology that selectively identifies, adsorbs, and kills “superbugs” in domestic and industrial wastewater.Recent research predicts that antibiotic-resistance bacteria (superbugs) will result in $100 trillion in health care expenses and 10 million deaths annually by 2050. The prevalence of superbugs in our water systems has increased due to corroded pipes, contamination, and climate change. Current drinking water disinfection technologies are designed to kill all types of bacteria before human consumption. However, for certain domestic and industrial applications there is a need to protect the good bacteria required for ecological processes that contribute to soil and plant health. Varanasi and Belcher will combine material, biological, process, and system engineering principles to design a sponge-based water disinfection technology that can identify and destroy harmful bacteria while leaving the good bacteria unharmed. By modifying the sponge surface with specialized nanomaterials, their approach will be able to kill superbugs faster and more efficiently. The sponge filters can be deployed under very low pressure, making them an affordable technology, especially in resource-constrained communities.In addition to the 10 seed grant projects, J-WAFS will also fund a research initiative led by Greg Sixt. Sixt is the research manager for climate and food systems at J-WAFS, and the director of the J-WAFS-led Food and Climate Systems Transformation (FACT) Alliance. His project focuses on the Lake Victoria Basin (LVB) of East Africa. The second-largest freshwater lake in the world, Lake Victoria straddles three countries (Uganda, Tanzania, and Kenya) and has a catchment area that encompasses two more (Rwanda and Burundi). Sixt will collaborate with Michael Hauser of the University of Natural Resources and Life Sciences, Vienna, and Paul Kariuki, of the Lake Victoria Basin Commission.The group will study how to adapt food systems to climate change in the Lake Victoria Basin. The basin is facing a range of climate threats that could significantly impact livelihoods and food systems in the expansive region. For example, extreme weather events like droughts and floods are negatively affecting agricultural production and freshwater resources. Across the LVB, current approaches to land and water management are unsustainable and threaten future food and water security. The Lake Victoria Basin Commission (LVBC), a specialized institution of the East African Community, wants to play a more vital role in coordinating transboundary land and water management to support transitions toward more resilient, sustainable, and equitable food systems. The primary goal of this research will be to support the LVBC’s transboundary land and water management efforts, specifically as they relate to sustainability and climate change adaptation in food systems. The research team will work with key stakeholders in Kenya, Uganda, and Tanzania to identify specific capacity needs to facilitate land and water management transitions. The two-year project will produce actionable recommendations to the LVBC. More

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      in Energy

      Finding “hot spots” where compounding environmental and economic risks converge

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      A computational tool developed by researchers at the MIT Joint Program on the Science and Policy of Global Change pinpoints specific counties within the United States that are particularly vulnerable to economic distress resulting from a transition from fossil fuels to low-carbon energy sources. By combining county-level data on employment in fossil fuel (oil, natural gas, and coal) industries with data on populations below the poverty level, the tool identifies locations with high risks for transition-driven economic hardship. It turns out that many of these high-risk counties are in the south-central U.S., with a heavy concentration in the lower portions of the Mississippi River.

      The computational tool, which the researchers call the System for the Triage of Risks from Environmental and Socio-economic Stressors (STRESS) platform, almost instantly displays these risk combinations on an easy-to-read visual map, revealing those counties that stand to gain the most from targeted green jobs retraining programs.  

      Drawing on data that characterize land, water, and energy systems; biodiversity; demographics; environmental equity; and transportation networks, the STRESS platform enables users to assess multiple, co-evolving, compounding hazards within a U.S. geographical region from the national to the county level. Because of its comprehensiveness and precision, this screening-level visualization tool can pinpoint risk “hot spots” that can be subsequently investigated in greater detail. Decision-makers can then plan targeted interventions to boost resilience to location-specific physical and economic risks.

      The platform and its applications are highlighted in a new study in the journal Frontiers in Climate.

      “As risks to natural and managed resources — and to the economies that depend upon them — become more complex, interdependent, and compounding amid rapid environmental and societal changes, they require more and more human and computational resources to understand and act upon,” says MIT Joint Program Deputy Director C. Adam Schlosser, the lead author of the study. “The STRESS platform provides decision-makers with an efficient way to combine and analyze data on those risks that matter most to them, identify ‘hot spots’ of compounding risk, and design interventions to minimize that risk.”

      In one demonstration of the STRESS platform’s capabilities, the study shows that national and global actions to reduce greenhouse gas emissions could simultaneously reduce risks to land, water, and air quality in the upper Mississippi River basin while increasing economic risks in the lower basin, where poverty and unemployment are already disproportionate. In another demonstration, the platform finds concerning “hot spots” where flood risk, poverty, and nonwhite populations coincide.

      The risk triage platform is based on an emerging discipline called multi-sector dynamics (MSD), which seeks to understand and model compounding risks and potential tipping points across interconnected natural and human systems. Tipping points occur when these systems can no longer sustain multiple, co-evolving stresses, such as extreme events, population growth, land degradation, drinkable water shortages, air pollution, aging infrastructure, and increased human demands. MSD researchers use observations and computer models to identify key precursory indicators of such tipping points, providing decision-makers with critical information that can be applied to mitigate risks and boost resilience in natural and managed resources. With funding from the U.S. Department of Energy, the MIT Joint Program has since 2018 been developing MSD expertise and modeling tools and using them to explore compounding risks and potential tipping points in selected regions of the United States.

      Current STRESS platform data includes more than 100 risk metrics at the county-level scale, but data collection is ongoing. MIT Joint Program researchers are continuing to develop the STRESS platform as an “open-science tool” that welcomes input from academics, researchers, industry and the general public. More

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      in Environment

      Four researchers with MIT ties earn 2023 Schmidt Science Fellowships

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      Four researchers with ties to MIT have been named Schmidt Science Fellows this year. Lillian Chin ’17, SM ’19; Neil Dalvie PD ’22, PhD ’22; Suong Nguyen, and Yirui Zhang SM ’19, PhD ’23 are among the 32 exceptional early-career scientists worldwide chosen to receive the prestigious fellowships.

      “History provides powerful examples of what happens when scientists are given the freedom to ask big questions which can achieve real breakthroughs across disciplines,” says Wendy Schmidt, co-founder of Schmidt Futures and president of the Schmidt Family Foundation. “Schmidt Science Fellows are tackling climate destruction, discovering new drugs against disease, developing novel materials, using machine learning to understand the drivers of human health, and much more. This new cohort will add to this legacy in applying scientific discovery to improve human health and opportunity, and preserve and restore essential planetary systems.”

      Schmidt Futures is a philanthropic initiative that brings talented people together in networks to prove out their ideas and solve hard problems in science and society. Schmidt Science Fellows receive a stipend of $100,000 a year for up to two years of postdoctoral research in a discipline different from their PhD at a world-leading lab anywhere across the globe.

      Lillian Chin ’17, SM ’19 is currently pursuing her PhD in the Department of Electrical Engineering and Computer Science. Her research focuses on creating new materials for robots. By designing the geometry of a material, Chin creates new “meta-materials” that have different properties from the original. Using this technique, she has created robot balls that dramatically expand in volume and soft grippers that can work in dangerous environments. All of these robots are built out of a single material, letting the researchers 3D print them with extra internal features like channels. These channels help to measure the deformation of metamaterials, enabling Chin and her collaborators to create robots that are strong, can move, and sense their own shape, like muscles do.

      “I feel very honored to have been chosen for this fellowship,” says Chin. “I feel like I proposed a very risky pivot, since my background is only in engineering, with very limited exposure to neuroscience. I’m very excited to be given the opportunity to learn best practices for interacting with patients and be able to translate my knowledge from robotics to biology.”

      With the Schmidt Fellowship, Chin plans to pursue new frontiers for custom materials with internal sensors, which can measure force and deformation and can be placed anywhere within the material. “I want to use these materials to make tools for clinicians and neuroscientists to better understand how humans touch and grasp objects around them,” says Chin. “I’m especially interested in seeing how my materials could help in diagnosis motor-related diseases or improve rehab outcomes by providing the patient with feedback. This will help me create robots that have a better sense of touch and learn how to move objects around like humans do.”

      Neil Dalvie PD ’22, PhD ’22 is a graduate of the Department of Chemical Engineering, where he worked with Professor J. Christopher Love on manufacturing of therapeutic proteins. Dalvie developed molecular biology techniques for manufacturing high-quality proteins in yeast, which enables rapid testing of new products and low-cost manufacturing and large scales. During the pandemic, he led a team that applied these learnings to develop a Covid-19 vaccine that was deployed in multiple low-income countries. After graduating, Dalvie wanted to apply the precision biological engineering that is routinely deployed in medicinal manufacturing to other large-scale bioprocesses.

      “It’s rare for scientists to cross large technical gaps after so many years of specific training to get a PhD — you get comfy being an expert in your field,” says Dalvie. “I was definitely intimidated by the giant leap from vaccine manufacturing to the natural rock cycle. The fellowship has allowed me to dive into the new field by removing immediate pressure to publish or find my next job. I am excited for what commonalities we will find between biomanufacturing and biogeochemistry.”

      As a Schmidt Science Fellow, Dalvie will work with Professor Pamela Silver at Harvard Medical School on engineering microorganisms for enhanced rock weathering and carbon sequestration to combat climate change. They are applying modern molecular biology to enhance natural biogeochemical processes at gigaton scales.

      Suong (Su) Nguyen, a postdoctoral researcher in Professor Jeremiah Johnson’s lab in the Department of Chemistry, earned her PhD from Princeton University, where she developed light-driven, catalytic methodologies for organic synthesis, biomass valorization, plastic waste recycling, and functionalization of quantum sensing materials.

      As a Schmidt Science fellow, Nguyen will pivot from organic chemistry to nanomaterials. Biological systems are able to synthesize macromolecules with precise structure essential for their biological function. Scientists have long dreamed of achieving similar control over synthetic materials, but existing methods are inefficient and limited in scope. Nguyen hopes to develop new strategies to achieve such high level of control over the structure and properties of nanomaterials and explore their potential for use in therapeutic applications.

      “I feel extremely honored and grateful to receive the Schmidt Science Fellowship,” says Nguyen. “The fellowship will provide me with a unique opportunity to engage with scientists from a very wide range of research backgrounds. I believe this will significantly shape the research objectives for my future career.”

      Yirui Zhang SM ’19, PhD ’22 is a graduate of the Department of Mechanical Engineering. Zhang’s research focuses on electrochemical energy storage and conversion, including lithium-ion batteries and electrocatalysis. She has developed in situ spectroscopy and electrochemical methods to probe the electrode-electrolyte interface, understand the interfacial molecular structures, and unravel the fundamental thermodynamics and kinetics of (electro)chemical reactions in energy storage. Further, she has leveraged the physical chemistry of liquids and tuned the molecular structures at the interface to improve the stability and kinetics of electrochemical reactions. 

      “I am honored and thrilled to have been named a Schmidt Science Fellow,” says Zhang. “The fellowship will not only provide me with the unique opportunity to broaden my scientific perspectives and pursue pivoting research, but also create a lifelong network for us to collaborate across diverse fields and become scientific and societal thought leaders. I look forward to pushing the boundaries of my research and advancing technologies to tackle global challenges in energy storage and health care with interdisciplinary efforts!”

      As a Schmidt Science Fellow, Zhang will work across disciplines and pivot to biosensing. She plans to combine spectroscopy, electrokinetics, and machine learning to develop a fast and cost-effective technique for monitoring and understanding infectious disease. The innovations will benefit next-generation point-of-care medical devices and wastewater-based epidemiology to provide timely diagnosis and help protect humans against deadly infections and antimicrobial resistance. More

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      in Environment

      Inaugural J-WAFS Grand Challenge aims to develop enhanced crop variants and move them from lab to land

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      According to MIT’s charter, established in 1861, part of the Institute’s mission is to advance the “development and practical application of science in connection with arts, agriculture, manufactures, and commerce.” Today, the Abdul Latif Jameel Water and Food Systems Lab (J-WAFS) is one of the driving forces behind water and food-related research on campus, much of which relates to agriculture. In 2022, J-WAFS established the Water and Food Grand Challenge Grant to inspire MIT researchers to work toward a water-secure and food-secure future for our changing planet. Not unlike MIT’s Climate Grand Challenges, the J-WAFS Grand Challenge seeks to leverage multiple areas of expertise, programs, and Institute resources. The initial call for statements of interests returned 23 letters from MIT researchers spanning 18 departments, labs, and centers. J-WAFS hosted workshops for the proposers to present and discuss their initial ideas. These were winnowed down to a smaller set of invited concept papers, followed by the final proposal stage. 

      Today, J-WAFS is delighted to report that the inaugural J-WAFS Grand Challenge Grant has been awarded to a team of researchers led by Professor Matt Shoulders and research scientist Robert Wilson of the Department of Chemistry. A panel of expert, external reviewers highly endorsed their proposal, which tackles a longstanding problem in crop biology — how to make photosynthesis more efficient. The team will receive $1.5 million over three years to facilitate a multistage research project that combines cutting-edge innovations in synthetic and computational biology. If successful, this project could create major benefits for agriculture and food systems worldwide.

      “Food systems are a major source of global greenhouse gas emissions, and they are also increasingly vulnerable to the impacts of climate change. That’s why when we talk about climate change, we have to talk about food systems, and vice versa,” says Maria T. Zuber, MIT’s vice president for research. “J-WAFS is central to MIT’s efforts to address the interlocking challenges of climate, water, and food. This new grant program aims to catalyze innovative projects that will have real and meaningful impacts on water and food. I congratulate Professor Shoulders and the rest of the research team on being the inaugural recipients of this grant.”

      Shoulders will work with Bryan Bryson, associate professor of biological engineering, as well as Bin Zhang, associate professor of chemistry, and Mary Gehring, a professor in the Department of Biology and the Whitehead Institute for Biomedical Research. Robert Wilson from the Shoulders lab will be coordinating the research effort. The team at MIT will work with outside collaborators Spencer Whitney, a professor from the Australian National University, and Ahmed Badran, an assistant professor at the Scripps Research Institute. A milestone-based collaboration will also take place with Stephen Long, a professor from the University of Illinois at Urbana-Champaign. The group consists of experts in continuous directed evolution, machine learning, molecular dynamics simulations, translational plant biochemistry, and field trials.

      “This project seeks to fundamentally improve the RuBisCO enzyme that plants use to convert carbon dioxide into the energy-rich molecules that constitute our food,” says J-WAFS Director John H. Lienhard V. “This difficult problem is a true grand challenge, calling for extensive resources. With J-WAFS’ support, this long-sought goal may finally be achieved through MIT’s leading-edge research,” he adds.

      RuBisCO: No, it’s not a new breakfast cereal; it just might be the key to an agricultural revolution

      A growing global population, the effects of climate change, and social and political conflicts like the war in Ukraine are all threatening food supplies, particularly grain crops. Current projections estimate that crop production must increase by at least 50 percent over the next 30 years to meet food demands. One key barrier to increased crop yields is a photosynthetic enzyme called Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase (RuBisCO). During photosynthesis, crops use energy gathered from light to draw carbon dioxide (CO2) from the atmosphere and transform it into sugars and cellulose for growth, a process known as carbon fixation. RuBisCO is essential for capturing the CO2 from the air to initiate conversion of CO2 into energy-rich molecules like glucose. This reaction occurs during the second stage of photosynthesis, also known as the Calvin cycle. Without RuBisCO, the chemical reactions that account for virtually all carbon acquisition in life could not occur.

      Unfortunately, RuBisCO has biochemical shortcomings. Notably, the enzyme acts slowly. Many other enzymes can process a thousand molecules per second, but RuBisCO in chloroplasts fixes less than six carbon dioxide molecules per second, often limiting the rate of plant photosynthesis. Another problem is that oxygen (O2) molecules and carbon dioxide molecules are relatively similar in shape and chemical properties, and RuBisCO is unable to fully discriminate between the two. The inadvertent fixation of oxygen by RuBisCO leads to energy and carbon loss. What’s more, at higher temperatures RuBisCO reacts even more frequently with oxygen, which will contribute to decreased photosynthetic efficiency in many staple crops as our climate warms.

      The scientific consensus is that genetic engineering and synthetic biology approaches could revolutionize photosynthesis and offer protection against crop losses. To date, crop RuBisCO engineering has been impaired by technological obstacles that have limited any success in significantly enhancing crop production. Excitingly, genetic engineering and synthetic biology tools are now at a point where they can be applied and tested with the aim of creating crops with new or improved biological pathways for producing more food for the growing population.

      An epic plan for fighting food insecurity

      The 2023 J-WAFS Grand Challenge project will use state-of-the-art, transformative protein engineering techniques drawn from biomedicine to improve the biochemistry of photosynthesis, specifically focusing on RuBisCO. Shoulders and his team are planning to build what they call the Enhanced Photosynthesis in Crops (EPiC) platform. The project will evolve and design better crop RuBisCO in the laboratory, followed by validation of the improved enzymes in plants, ultimately resulting in the deployment of enhanced RuBisCO in field trials to evaluate the impact on crop yield. 

      Several recent developments make high-throughput engineering of crop RuBisCO possible. RuBisCO requires a complex chaperone network for proper assembly and function in plants. Chaperones are like helpers that guide proteins during their maturation process, shielding them from aggregation while coordinating their correct assembly. Wilson and his collaborators previously unlocked the ability to recombinantly produce plant RuBisCO outside of plant chloroplasts by reconstructing this chaperone network in Escherichia coli (E. coli). Whitney has now established that the RuBisCO enzymes from a range of agriculturally relevant crops, including potato, carrot, strawberry, and tobacco, can also be expressed using this technology. Whitney and Wilson have further developed a range of RuBisCO-dependent E. coli screens that can identify improved RuBisCO from complex gene libraries. Moreover, Shoulders and his lab have developed sophisticated in vivo mutagenesis technologies that enable efficient continuous directed evolution campaigns. Continuous directed evolution refers to a protein engineering process that can accelerate the steps of natural evolution simultaneously in an uninterrupted cycle in the lab, allowing for rapid testing of protein sequences. While Shoulders and Badran both have prior experience with cutting-edge directed evolution platforms, this will be the first time directed evolution is applied to RuBisCO from plants.

      Artificial intelligence is changing the way enzyme engineering is undertaken by researchers. Principal investigators Zhang and Bryson will leverage modern computational methods to simulate the dynamics of RuBisCO structure and explore its evolutionary landscape. Specifically, Zhang will use molecular dynamics simulations to simulate and monitor the conformational dynamics of the atoms in a protein and its programmed environment over time. This approach will help the team evaluate the effect of mutations and new chemical functionalities on the properties of RuBisCO. Bryson will employ artificial intelligence and machine learning to search the RuBisCO activity landscape for optimal sequences. The computational and biological arms of the EPiC platform will work together to both validate and inform each other’s approaches to accelerate the overall engineering effort.

      Shoulders and the group will deploy their designed enzymes in tobacco plants to evaluate their effects on growth and yield relative to natural RuBisCO. Gehring, a plant biologist, will assist with screening improved RuBisCO variants using the tobacco variety Nicotiana benthamianaI, where transient expression can be deployed. Transient expression is a speedy approach to test whether novel engineered RuBisCO variants can be correctly synthesized in leaf chloroplasts. Variants that pass this quality-control checkpoint at MIT will be passed to the Whitney Lab at the Australian National University for stable transformation into Nicotiana tabacum (tobacco), enabling robust measurements of photosynthetic improvement. In a final step, Professor Long at the University of Illinois at Urbana-Champaign will perform field trials of the most promising variants.

      Even small improvements could have a big impact

      A common criticism of efforts to improve RuBisCO is that natural evolution has not already identified a better enzyme, possibly implying that none will be found. Traditional views have speculated a catalytic trade-off between RuBisCO’s specificity factor for CO2 / O2 versus its CO2 fixation efficiency, leading to the belief that specificity factor improvements might be offset by even slower carbon fixation or vice versa. This trade-off has been suggested to explain why natural evolution has been slow to achieve a better RuBisCO. But Shoulders and the team are convinced that the EPiC platform can unlock significant overall improvements to plant RuBisCO. This view is supported by the fact that Wilson and Whitney have previously used directed evolution to improve CO2 fixation efficiency by 50 percent in RuBisCO from cyanobacteria (the ancient progenitors of plant chloroplasts) while simultaneously increasing the specificity factor. 

      The EPiC researchers anticipate that their initial variants could yield 20 percent increases in RuBisCO’s specificity factor without impairing other aspects of catalysis. More sophisticated variants could lift RuBisCO out of its evolutionary trap and display attributes not currently observed in nature. “If we achieve anywhere close to such an improvement and it translates to crops, the results could help transform agriculture,” Shoulders says. “If our accomplishments are more modest, it will still recruit massive new investments to this essential field.”

      Successful engineering of RuBisCO would be a scientific feat of its own and ignite renewed enthusiasm for improving plant CO2 fixation. Combined with other advances in photosynthetic engineering, such as improved light usage, a new green revolution in agriculture could be achieved. Long-term impacts of the technology’s success will be measured in improvements to crop yield and grain availability, as well as resilience against yield losses under higher field temperatures. Moreover, improved land productivity together with policy initiatives would assist in reducing the environmental footprint of agriculture. With more “crop per drop,” reductions in water consumption from agriculture would be a major boost to sustainable farming practices.

      “Our collaborative team of biochemists and synthetic biologists, computational biologists, and chemists is deeply integrated with plant biologists and field trial experts, yielding a robust feedback loop for enzyme engineering,” Shoulders adds. “Together, this team will be able to make a concerted effort using the most modern, state-of-the-art techniques to engineer crop RuBisCO with an eye to helping make meaningful gains in securing a stable crop supply, hopefully with accompanying improvements in both food and water security.” More

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      in Environment

      Exploring the bow shock and beyond

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      For most people, the night sky conjures a sense of stillness, an occasional shooting star the only visible movement. A conversation with Rishabh Datta, however, unveils the supersonic drama crashing above planet Earth. The PhD candidate has focused his recent study on the plasma speeding through space, flung from sources like the sun’s corona and headed toward Earth, halted abruptly by colliding with the planet’s magnetosphere. The resulting shock wave is similar to the “bow shock” that forms around the nose cone of a supersonic jet, which manifests as the familiar sonic boom.

      The bow shock phenomenon has been well studied. “It’s probably one of the things that’s keeping life alive,” says Datta, “protecting us from the solar wind.” While he feels the magnetosphere provides “a very interesting space laboratory,” Datta’s main focus is, “Can we create this high-energy plasma that is moving supersonically in a laboratory, and can we study it? And can we learn things that are hard to diagnose in an astrophysical plasma?”

      Datta’s research journey to the bow shock and beyond began when he joined a research program for high school students at the National University Singapore. Tasked with culturing bacteria and measuring the amount of methane they produced in a biogas tank, Datta found his first research experience “quite nasty.”

      “I was working with chicken manure, and every day I would come home smelling completely awful,” he says.

      As an undergraduate at Georgia Tech, Datta’s interests turned toward solar power, compelled by a new technology he felt could generate sustainable energy. By the time he joined MIT’s Department of Mechanical Engineering, though, his interests had morphed into researching the heat and mass transfer from airborne droplets. After a year of study, he felt the need to go in a yet another direction.

      The subject of astrophysical plasmas had recently piqued his interest, and he followed his curiosity to Department of Nuclear Science and Engineering Professor Nuno Loureiro’s introductory plasma class. There he encountered Professor Jack Hare, who was sitting in on the class and looking for students to work with him.

      “And that’s how I ended up doing plasma physics and studying bow shocks,” he says, “a long and circuitous route that started with culturing bacteria.”

      Gathering measurements from MAGPIE

      Datta is interested in what he can learn about plasma from gathering measurements of a laboratory-created bow shock, seeking to verify theoretical models. He uses data already collected from experiments on a pulsed-power generator known as MAGPIE (the Mega-Ampere Generator of Plasma Implosion Experiments), located at Imperial College, London. By observing how long it takes a plasma to reach an obstacle, in this case a probe that measures magnetic fields, Datta was able to determine its velocity.   

      With the velocity established, an interferometry system was able to provide images of the probe and the plasma around it, allowing Datta to characterize the structure of the bow shock.

      “The shape depends on how fast sound waves can travel in a plasma,” says Datta. “And this ‘sound speed’ depends on the temperature.”

      The interdependency of these characteristics means that by imaging a shock it’s possible to determine temperature, sound speed, and other measurements more easily and cheaply than with other methods.

      “And knowing more about your plasma allows you to make predictions about, for example, electrical resistivity, which can be important for understanding other physics that might interest you,” says Datta, “like magnetic reconnection.”

      This phenomenon, which controls the evolution of such violent events as solar flares, coronal mass ejections, magnetic storms that drive auroras, and even disruptions in fusion tokamaks, has become the focus of his recent research. It happens when opposing magnetic fields in a plasma break and then reconnect, generating vast quantities of heat and accelerating the plasma to high velocities.

      Onward to Z

      Datta travels to Sandia National Laboratories in Albuquerque, New Mexico, to work on the largest pulsed power facility in the world, informally known as “the Z machine,” to research how the properties of magnetic reconnection change when a plasma emits strong radiation and cools rapidly.

      In future years, Datta will only have to travel across Albany Street on the MIT campus to work on yet another machine, PUFFIN, currently being built at the Plasma Science and Fusion Center (PSFC). Like MAGPIE and Z, PUFFIN is a pulsed power facility, but with the ability to drive the current 10 times longer than other machines, opening up new opportunities in high-energy-density laboratory astrophysics.

      Hare, who leads the PUFFIN team, is pleased with Datta’s increasing experience.

      “Working with Rishabh is a real pleasure,” he says, “He has quickly learned the ins and outs of experimental plasma physics, often analyzing data from machines he hasn’t even yet had the chance to see! While we build PUFFIN it’s really useful for us to carry out experiments at other pulsed-power facilities worldwide, and Rishabh has already written papers on results from MAGPIE, COBRA at Cornell in Ithaca, New York, and the Z Machine.”

      Pursuing climate action at MIT

      Hand-in-hand with Datta’s quest to understand plasma is his pursuit of sustainability, including carbon-free energy solutions. A member of the Graduate Student Council’s Sustainability Committee since he arrived in 2019, he was heartened when MIT, revising their climate action plan, provided him and other students the chance to be involved in decision-making. He led focus groups to provide graduate student input on the plan, raising issues surrounding campus decarbonization, the need to expand hiring of early-career researchers working on climate and sustainability, and waste reduction and management for MIT laboratories.

      When not focused on bringing astrophysics to the laboratory, Datta sometimes experiments in a lab closer to home — the kitchen — where he often challenges himself to duplicate a recipe he has recently tried at a favorite restaurant. His stated ambition could apply to his sustainability work as well as to his pursuit of understanding plasma.

      “The goal is to try and make it better,” he says. “I try my best to get there.”

      Datta’s work has been funded, in part, by the National Science Foundation, National Nuclear Security Administration, and the Department of Energy. More

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      in Energy

      Exploring new sides of climate and sustainability research

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      When the MIT Climate and Sustainability Consortium (MCSC) launched its Climate and Sustainability Scholars Program in fall 2022, the goal was to offer undergraduate students a unique way to develop and implement research projects with the strong support of each other and MIT faculty. Now into its second semester, the program is underscoring the value of fostering this kind of network — a community with MIT students at its core, exploring their diverse interests and passions in the climate and sustainability realms.Inspired by MIT’s successful SuperUROP [Undergraduate Research Opportunities Program], the yearlong MCSC Climate and Sustainability Scholars Program includes a classroom component combined with experiential learning opportunities and mentorship, all centered on climate and sustainability topics.“Harnessing the innovation, passion, and expertise of our talented students is critical to MIT’s mission of tackling the climate crisis,” says Anantha P. Chandrakasan, dean of the School of Engineering, Vannevar Bush Professor of Electrical Engineering and Computer Science, and chair of the MCSC. “The program is helping train students from a variety of disciplines and backgrounds to be effective leaders in climate and sustainability-focused roles in the future.”

      “What we found inspiring about MIT’s existing SuperUROP program was how it provides students with the guidance, training, and resources they need to investigate the world’s toughest problems,” says Elsa Olivetti, the Esther and Harold E. Edgerton Associate Professor in Materials Science and Engineering and MCSC co-director. “This incredible level of support and mentorship encourages students to think and explore in creative ways, make new connections, and develop strategies and solutions that propel their work forward.”The first and current cohort of Climate and Sustainability Scholars consists of 19 students, representing MIT’s School of Engineering, MIT Schwarzman College of Computing, School of Science, School of Architecture and Planning, and MIT Sloan School of Management. These students are learning new perspectives, approaches, and angles in climate and sustainability — from each other, MIT faculty, and industry professionals.Projects with real-world applicationsStudents in the program work directly with faculty and principal investigators across MIT to develop their research projects focused on a large scope of sustainability topics.

      “This broad scope is important,” says Desirée Plata, MIT’s Gilbert W. Winslow Career Development Professor in Civil and Environmental Engineering, “because climate and sustainability solutions are needed in every facet of society. For a long time, people were searching for a ‘silver bullet’ solution to the climate change problems, but we didn’t get to this point with a single technological decision. This problem was created across a spectrum of sociotechnological activities, and fundamentally different thinking across a spectrum of solutions is what’s needed to move us forward. MCSC students are working to provide those solutions.”

      Undergraduate student and physics major M. (MG) Geogdzhayeva is working with Raffaele Ferrari, Cecil and Ida Green Professor of Oceanography in the Department of Earth, Atmospheric and Planetary Sciences, and director of the Program in Atmospheres, Oceans, and Climate, on their project “Using Continuous Time Markov Chains to Project Extreme Events under Climate.” Geogdzhayeva’s research supports the Flagship Climate Grand Challenges project that Ferrari is leading along with Professor Noelle Eckley Selin.

      “The project I am working on has a similar approach to the Climate Grand Challenges project entitled “Bringing computation to the climate challenge,” says Geogdzhayeva. “I am designing an emulator for climate extremes. Our goal is to boil down climate information to what is necessary and to create a framework that can deliver specific information — in order to develop valuable forecasts. As someone who comes from a physics background, the Climate and Sustainability Scholars Program has helped me think about how my research fits into the real world, and how it could be implemented.”

      Investigating technology and stakeholders

      Within technology development, Jade Chongsathapornpong, also a physics major, is diving into photo-modulated catalytic reactions for clean energy applications. Chongsathapornpong, who has worked with the MCSC on carbon capture and sequestration through the Undergraduate Research Opportunities Program (UROP), is now working with Harry Tuller, MIT’s R.P. Simmons Professor of Ceramics and Electronic Materials. Louise Anderfaas, majoring in materials science and engineering, is also working with Tuller on her project “Robust and High Sensitivity Detectors for Exploration of Deep Geothermal Wells.”Two other students who have worked with the MCSC through UROP include Paul Irvine, electrical engineering and computer science major, who is now researching American conservatism’s current relation to and views about sustainability and climate change, and Pamela Duke, management major, now investigating the use of simulation tools to empower industrial decision-makers around climate change action.Other projects focusing on technology development include the experimental characterization of poly(arylene ethers) for energy-efficient propane/propylene separations by Duha Syar, who is a chemical engineering major and working with Zachary Smith, the Robert N. Noyce Career Development Professor of Chemical Engineering; developing methods to improve sheet steel recycling by Rebecca Lizarde, who is majoring in materials science and engineering; and ion conduction in polymer-ceramic composite electrolytes by Melissa Stok, also majoring in materials science and engineering.

      Melissa Stok, materials science and engineering major, during a classroom discussion.

      Photo: Andrew Okyere

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      “My project is very closely connected to developing better Li-Ion batteries, which are extremely important in our transition towards clean energy,” explains Stok, who is working with Bilge Yildiz, MIT’s Breene M. Kerr (1951) Professor of Nuclear Science and Engineering. “Currently, electric cars are limited in their range by their battery capacity, so working to create more effective batteries with higher energy densities and better power capacities will help make these cars go farther and faster. In addition, using safer materials that do not have as high of an environmental toll for extraction is also important.” Claire Kim, a chemical engineering major, is focusing on batteries as well, but is honing in on large form factor batteries more relevant for grid-scale energy storage with Fikile Brushett, associate professor of chemical engineering.Some students in the program chose to focus on stakeholders, which, when it comes to climate and sustainability, can range from entities in business and industry to farmers to Indigenous people and their communities. Shivani Konduru, an electrical engineering and computer science major, is exploring the “backfire effects” in climate change communication, focusing on perceptions of climate change and how the messenger may change outcomes, and Einat Gavish, mathematics major, on how different stakeholders perceive information on driving behavior.Two students are researching the impact of technology on local populations. Anushree Chaudhuri, who is majoring in urban studies and planning, is working with Lawrence Susskind, Ford Professor of Urban and Environmental Planning, on community acceptance of renewable energy siting, and Amelia Dogan, also an urban studies and planning major, is working with Danielle Wood, assistant professor of aeronautics and astronautics and media arts and sciences, on Indigenous data sovereignty in environmental contexts.

      “I am interviewing Indigenous environmental activists for my project,” says Dogan. “This course is the first one directly related to sustainability that I have taken, and I am really enjoying it. It has opened me up to other aspects of climate beyond just the humanity side, which is my focus. I did MIT’s SuperUROP program and loved it, so was excited to do this similar opportunity with the climate and sustainability focus.”

      Other projects include in-field monitoring of water quality by Dahlia Dry, a physics major; understanding carbon release and accrual in coastal wetlands by Trinity Stallins, an urban studies and planning major; and investigating enzyme synthesis for bioremediation by Delight Nweneka, an electrical engineering and computer science major, each linked to the MCSC’s impact pathway work in nature-based solutions.

      The wide range of research topics underscores the Climate and Sustainability Program’s goal of bringing together diverse interests, backgrounds, and areas of study even within the same major. For example, Helena McDonald is studying pollution impacts of rocket launches, while Aviva Intveld is analyzing the paleoclimate and paleoenvironment background of the first peopling of the Americas. Both students are Earth, atmospheric and planetary sciences majors but are researching climate impacts from very different perspectives. Intveld was recently named a 2023 Gates Cambridge Scholar.

      “There are students represented from several majors in the program, and some people are working on more technical projects, while others are interpersonal. Both approaches are really necessary in the pursuit of climate resilience,” says Grace Harrington, who is majoring in civil and environmental engineering and whose project investigates ways to optimize the power of the wind farm. “I think it’s one of the few classes I’ve taken with such an interdisciplinary nature.”

      Shivani Konduru, electrical engineering and computer science major, during a classroom lecture

      Photo: Andrew Okyere

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      Perspectives and guidance from MIT and industry expertsAs students are developing these projects, they are also taking the program’s course (Climate.UAR), which covers key topics in climate change science, decarbonization strategies, policy, environmental justice, and quantitative methods for evaluating social and environmental impacts. The course is cross-listed in departments across all five schools and is taught by an experienced and interdisciplinary team. Desirée Plata was central to developing the Climate and Sustainability Scholars Programs and course with Associate Professor Elsa Olivetti, who taught the first semester. Olivetti is now co-teaching the second semester with Jeffrey C. Grossman, the Morton and Claire Goulder and Family Professor in Environmental Systems, head of the Department of Materials Science and Engineering, and MCSC co-director. The course’s writing instructors are Caroline Beimford and David Larson.  

      “I have been introduced to a lot of new angles in the climate space through the weekly guest lecturers, who each shared a different sustainability-related perspective,” says Claire Kim. “As a chemical engineering major, I have mostly looked into the technologies for decarbonization, and how to scale them, so learning about policy, for example, was helpful for me. Professor Black from the Department of History spoke about how we can analyze the effectiveness of past policy to guide future policy, while Professor Selin talked about framing different climate policies as having co-benefits. These perspectives are really useful because no matter how good a technology is, you need to convince other people to adopt it, or have strong policy in place to encourage its use, in order for it to be effective.”

      Bringing the industry perspective, guests have presented from MCSC member companies such as PepsiCo, Holcim, Apple, Cargill, and Boeing. As an example, in one class, climate leaders from three companies presented together on their approaches to setting climate goals, barriers to reaching them, and ways to work together. “When I presented to the class, alongside my counterparts at Apple and Boeing, the student questions pushed us to explain how can collaborate on ways to achieve our climate goals, reflecting the broader opportunity we find within the MCSC,” says Dana Boyer, sustainability manager at Cargill.

      Witnessing the cross-industry dynamics unfold in class was particularly engaging for the students. “The most beneficial part of the program for me is the number of guest lectures who have come in to the class, not only from MIT but also from the industry side,” Grace Harrington adds. “The diverse range of people talking about their own fields has allowed me to make connections between all my classes.”Bringing in perspectives from both academia and industry is a reflection of the MCSC’s larger mission of linking its corporate members with each other and with the MIT community to develop scalable climate solutions.“In addition to focusing on an independent research project and engaging with a peer community, we’ve had the opportunity to hear from speakers across the sustainability space who are also part of or closely connected to the MIT ecosystem,” says Anushree Chaudhuri. “These opportunities have helped me make connections and learn about initiatives at the Institute that are closely related to existing or planned student sustainability projects. These connections — across topics like waste management, survey best practices, and climate communications — have strengthened student projects and opened pathways for future collaborations.

      Basuhi Ravi, MIT PhD candidate, giving a guest lecture

      Photo: Andrew Okyere

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      Having a positive impact as students and after graduation

      At the start of the program, students identified several goals, including developing focused independent research questions, drawing connections and links with real-world challenges, strengthening their critical thinking skills, and reflecting on their future career ambitions. A common thread throughout them all: the commitment to having a meaningful impact on climate and sustainability challenges both as students now, and as working professionals after graduation.“I’ve absolutely loved connecting with like-minded peers through the program. I happened to know most of the students coming in from various other communities on campus, so it’s been a really special experience for all of these people who I couldn’t connect with as a cohesive cohort before to come together. Whenever we have small group discussions in class, I’m always grateful for the time to learn about the interdisciplinary research projects everyone is involved with,” concludes Chaudhuri. “I’m looking forward to staying in touch with this group going forward, since I think most of us are planning on grad school and/or careers related to climate and sustainability.”

      The MCSC Climate and Sustainability Scholars Program is representative of MIT’s ambitious and bold initiatives on climate and sustainability — bringing together faculty and students across MIT to collaborate with industry on developing climate and sustainability solutions in the context of undergraduate education and research. Learn about how you can get involved. More

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      3 Questions: New MIT major and its role in fighting climate change

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      Launched this month, MIT’s new Bachelor of Science in climate system science and engineering is jointly offered by the departments of Civil and Environmental Engineering (CEE) and Earth, Atmospheric and Planetary Sciences (EAPS). As part of MIT’s commitment to aid the global response to climate change, the new degree program is designed to train the next generation of leaders, providing a foundational understanding of both the Earth system and engineering principles — as well as an understanding of human and institutional behavior as it relates to the climate challenge. Jadbabaie and Van der Hilst discuss the new Course 1-12 multidisciplinary major and why it’s needed now at MIT. 

      Q: What was the idea behind launching this new major at MIT?

      Jadbabaie: Climate change is an incredibly important issue that we must address, and time is of the essence. MIT is in a unique position to play a leadership role in this effort. We not only have the ability to advance the science of climate change and deepen our understanding of the climate system, but also to develop innovative engineering solutions for sustainability that can help us meet the climate goals set forth in the Paris Agreement. It is important that our educational approach also incorporates other aspects of this cross-cutting issue, ranging from climate justice, policy, to economics, and MIT is the perfect place to make this happen. With Course 1’s focus on sustainability across scales, from the nano to the global scale, and with Course 12 studying Earth system science in general, it was a natural fit for CEE and EAPS to tackle this challenge together. It is my belief that we can leverage our collective expertise and resources to make meaningful progress. There has never been a more crucial time for us to advance students’ understanding of both climate science and engineering, as well as their understanding of the societal implications of climate risk.

      Van der Hilst: Climate change is a global issue, and the solutions we urgently need for building a net-zero future must consider how everything is connected. The Earth’s climate is a complex web of cause and effect between the oceans, atmosphere, ecosystems, and processes that shape the surface and environmental systems of the planet. To truly understand climate risks, we need to understand the fundamental science that governs these interconnected systems — and we need to consider the ways that human activity influences their behavior. The types of large-scale engineering projects that we need to secure a sustainable future must take into consideration the Earth system itself. A systems approach to modeling is crucial if we are to succeed at inventing, designing, and implementing solutions that can reduce greenhouse gas emissions, build climate resilience, and mitigate the inevitable climate-related natural disasters that we’ll face. That’s why our two departments are collaborating on a degree program that equips students with foundational climate science knowledge alongside fundamental engineering principles in order to catalyze the innovation we’ll need to meet the world’s 2050 goals.

      Q: How is MIT uniquely positioned to lead undergraduate education in climate system science and engineering? 

      Jadbabaie: It’s a great example of how MIT is taking a leadership role and multidisciplinary approach to tackling climate change by combining engineering and climate system science in one undergraduate major. The program leverages MIT’s academic strengths, focusing on teaching hard analytical and computational skills while also providing a curriculum that includes courses in a wide range of topics, from climate economics and policy to ethics, climate justice, and even climate literature, to help students develop an understanding of the political and social issues that are tied to climate change. Given the strong ties between courses 1 and 12, we want the students in the program to be full members of both departments, as well as both the School of Engineering and the School of Science. And, being MIT, there is no shortage of opportunities for undergraduate research and entrepreneurship — in fact, we specifically encourage students to participate in the active research of the departments. The knowledge and skills our students gain will enable them to serve the nation and the world in a meaningful way as they tackle complex global-scale environmental problems. The students at MIT are among the most passionate and driven people out there. I’m really excited to see what kind of innovations and solutions will come out of this program in the years to come. I think this undergraduate major is a fantastic step in the right direction.

      Q: What opportunities will the major provide to students for addressing climate change?

      Van der Hilst: Both industry and government are actively seeking new talent to respond to the challenges — and opportunities — posed by climate change and our need to build a sustainable future. What’s exciting is that many of the best jobs in this field call for leaders who can combine the analytical skill of a scientist with the problem-solving mindset of an engineer. That’s exactly what this new degree program at MIT aims to prepare students for — in an expanding set of careers in areas like renewable energy, civil infrastructure, risk analysis, corporate sustainability, environmental advocacy, and policymaking. But it’s not just about career opportunities. It’s also about making a real difference and safeguarding our future. It’s not too late to prevent much more damaging changes to Earth’s climate. Indeed, whether in government, industry, or academia, MIT students are future leaders — as such it is critically important that all MIT students understand the basics of climate system science and engineering along with math, physics, chemistry, and biology. The new Course 1-12 degree was designed to forge students who are passionate about protecting our planet into the next generation of leaders who can fast-track high-impact, science-based solutions to aid the global response, with an eye toward addressing some of the uneven social impacts inherent in the climate crisis. More

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      in Energy

      Moving perovskite advancements from the lab to the manufacturing floor

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      The following was issued as a joint announcement from MIT.nano and the MIT Research Laboratory for Electronics; CubicPV; Verde Technologies; Princeton University; and the University of California at San Diego.

      Tandem solar cells are made of stacked materials — such as silicon paired with perovskites — that together absorb more of the solar spectrum than single materials, resulting in a dramatic increase in efficiency. Their potential to generate significantly more power than conventional cells could make a meaningful difference in the race to combat climate change and the transition to a clean-energy future.

      However, current methods to create stable and efficient perovskite layers require time-consuming, painstaking rounds of design iteration and testing, inhibiting their development for commercial use. Today, the U.S. Department of Energy Solar Energy Technologies Office (SETO) announced that MIT has been selected to receive an $11.25 million cost-shared award to establish a new research center to address this challenge by using a co-optimization framework guided by machine learning and automation.

      A collaborative effort with lead industry participant CubicPV, solar startup Verde Technologies, and academic partners Princeton University and the University of California San Diego (UC San Diego), the center will bring together teams of researchers to support the creation of perovskite-silicon tandem solar modules that are co-designed for both stability and performance, with goals to significantly accelerate R&D and the transfer of these achievements into commercial environments.

      “Urgent challenges demand rapid action. This center will accelerate the development of tandem solar modules by bringing academia and industry into closer partnership,” says MIT professor of mechanical engineering Tonio Buonassisi, who will direct the center. “We’re grateful to the Department of Energy for supporting this powerful new model and excited to get to work.”

      Adam Lorenz, CTO of solar energy technology company CubicPV, stresses the importance of thinking about scale, alongside quality and efficiency, to accelerate the perovskite effort into the commercial environment. “Instead of chasing record efficiencies with tiny pixel-sized devices and later attempting to stabilize them, we will simultaneously target stability, reproducibility, and efficiency,” he says. “It’s a module-centric approach that creates a direct channel for R&D advancements into industry.”

      The center will be named Accelerated Co-Design of Durable, Reproducible, and Efficient Perovskite Tandems, or ADDEPT. The grant will be administered through the MIT Research Laboratory for Electronics (RLE).

      David Fenning, associate professor of nanoengineering at UC San Diego, has worked with Buonassisi on the idea of merging materials, automation, and computation, specifically in this field of artificial intelligence and solar, since 2014. Now, a central thrust of the ADDEPT project will be to deploy machine learning and robotic screening to optimize processing of perovskite-based solar materials for efficiency and durability.

      “We have already seen early indications of successful technology transfer between our UC San Diego robot PASCAL and industry,” says Fenning. “With this new center, we will bring research labs and the emerging perovskite industry together to improve reproducibility and reduce time to market.”

      “Our generation has an obligation to work collaboratively in the fight against climate change,” says Skylar Bagdon, CEO of Verde Technologies, which received the American-Made Perovskite Startup Prize. “Throughout the course of this center, Verde will do everything in our power to help this brilliant team transition lab-scale breakthroughs into the world where they can have an impact.”

      Several of the academic partners echoed the importance of the joint effort between academia and industry. Barry Rand, professor of electrical and computer engineering at the Andlinger Center for Energy and the Environment at Princeton University, pointed to the intersection of scientific knowledge and market awareness. “Understanding how chemistry affects films and interfaces will empower us to co-design for stability and performance,” he says. “The center will accelerate this use-inspired science, with close guidance from our end customers, the industry partners.”

      A critical resource for the center will be MIT.nano, a 200,000-square-foot research facility set in the heart of the campus. MIT.nano Director Vladimir Bulović, the Fariborz Maseeh (1990) Professor of Emerging Technology, says he envisions MIT.nano as a hub for industry and academic partners, facilitating technology development and transfer through shared lab space, open-access equipment, and streamlined intellectual property frameworks.

      “MIT has a history of groundbreaking innovation using perovskite materials for solar applications,” says Bulović. “We’re thrilled to help build on that history by anchoring ADDEPT at MIT.nano and working to help the nation advance the future of these promising materials.”

      MIT was selected as a part of the SETO Fiscal Year 2022 Photovoltaics (PV) funding program, an effort to reduce costs and supply chain vulnerabilities, further develop durable and recyclable solar technologies, and advance perovskite PV technologies toward commercialization. ADDEPT is one project that will tackle perovskite durability, which will extend module life. The overarching goal of these projects is to lower the levelized cost of electricity generated by PV.

      Research groups involved with the ADDEPT project at MIT include Buonassisi’s Accelerated Materials Laboratory for Sustainability (AMLS), Bulović’s Organic and Nanostructured Electronics (ONE) Lab, and the Bawendi Group led by Lester Wolfe Professor in Chemistry Moungi Bawendi. Also working on the project is Jeremiah Mwaura, research scientist in the ONE Lab. More