Watson, J. B. & Morgan, J. J. B. Emotional reactions and psychological experimentation. Am. J. Psychol. 28, 163–174 (1917).
Google Scholar
Watson, J. B. & Rayner, R. Conditioned emotional reactions. J. Exp. Psychol. 3, 1–14 (1920).
Google Scholar
LeDoux, J. Fear and the brain: where have we been, and where are we going. Biol. Psychiatry 44, 1229–1238 (1998).
Google Scholar
Fendt, M. & Fanselow, M. S. The neuroanatomical and neurochemical basis of conditioned fear. Neurosci. Biobehav. Rev. 23, 743–760 (1999).
Google Scholar
Maren, S. & Quirk, G. J. Neuronal signalling of fear memory. Nat. Rev. Neurosci. 5, 844–852 (2004).
Google Scholar
Bouton, M. E., Mineka, S. & Barlow, D. H. A modern learning theory perspective on the etiology of panic disorder. Psychol. Rev. 108, 4–32 (2001).
Google Scholar
Kim, J. J. & Jung, M. W. Neural circuits and mechanisms involved in Pavlovian fear conditioning: a critical review. Neurosci. Biobehav. Rev. 30, 188–202 (2006).
Google Scholar
Watson, J. B. Psychology as the behaviorist views it. Psychological Rev. 20, 158–177 (1913).
Google Scholar
Pavlov, I. P. Conditioned Reflexes: An Investigation of the Physiological Activity of the Cerebral Cortex (Oxford University Press, 1927).
Guthrie, E. R. Conditioning as a principle of learning. Psychological Rev. 37, 412–428 (1930).
Google Scholar
Kamin, L. J. in Miami Symposium on the Prediction of Behavior (ed. Jones, M. R.) 9–33 (University of Miami Press, 1968).
Rescorla, R. A. Probability of shock in the presence and absence of CS in fear conditioning. J. Comp. Physiol. Psychol. 66, 1–5 (1968).
Google Scholar
Wagner, A. R., Logan, F. A., Haberlandt, K. & Price, T. Stimulus selection in animal discrimination learning. J. Exp. Psychol. 76, 171–180 (1968).
Google Scholar
Rescorla, R. A. & Wagner, A. R. A Theory of Pavlovian Conditioning: Variations in the Effectiveness of Reinforcement and Nonreinforcement 64–99 (Appleton-Century-Crofts, 1972).
Josselyn, S. A. & Tonegawa, S. Memory engrams: recalling the past and imagining the future. Science 367, https://doi.org/10.1126/science.aaw4325 (2020).
Tovote, P., Fadok, J. P. & Luthi, A. Neuronal circuits for fear and anxiety. Nat. Rev. Neurosci. 16, 317–331 (2015).
Google Scholar
Haubensak, W. et al. Genetic dissection of an amygdala microcircuit that gates conditioned fear. Nature 468, 270–276 (2010).
Google Scholar
Foa, E. B. & Rothbaum, B. O. Treating the Trauma of Rape: Cognitive Behavioral Therapy for PTSD (Guilford Press, 1998).
Butler, A. C., Chapman, J. E., Forman, E. M. & Beck, A. T. The empirical status of cognitive-behavioral therapy: a review of meta-analyses. Clin. Psychol. Rev. 26, 17–31 (2006).
Google Scholar
Delgado, M. R., Olsson, A. & Phelps, E. A. Extending animal models of fear conditioning to humans. Biol. Psychol. 73, 39–48 (2006).
Google Scholar
Mahan, A. L. & Ressler, K. J. Fear conditioning, synaptic plasticity and the amygdala: implications for posttraumatic stress disorder. Trends Neurosci. 35, 24–35 (2012).
Google Scholar
Craske, M. G. et al. What is an anxiety disorder? Focus 9, 20 (2011).
LeDoux, J. E. The Emotional Brain: the Mysterious Underpinnings of Emotional Life (Simon & Schuster, 1996).
Fanselow, M. S. From contextual fear to a dynamic view of memory systems. Trends Cogn. Sci. 14, 7–15 (2010).
Google Scholar
Lima, S. L. & Dill, L. M. Behavioral decisions made under the risk of predation—a review and prospectus. Can. J. Zool. 68, 619–640 (1990).
Google Scholar
Bednekoff, P. A. Foraging in the Face of Danger 305–329 (University of Chicago Press, 2007).
Stephens, D. W. Decision ecology: foraging and the ecology of animal decision making. Cogn. Affect Behav. Neurosci. 8, 475–484 (2008).
Google Scholar
Beckers, T., Krypotos, A. M., Boddez, Y., Effting, M. & Kindt, M. What’s wrong with fear conditioning? Biol. Psychol. 92, 90–96 (2013).
Google Scholar
Mobbs, D. & Kim, J. J. Neuroethological studies of fear, anxiety, and risky decision-making in rodents and humans. Curr. Opin. Behav. Sci. 5, 8–15 (2015).
Google Scholar
Pellman, B. A. & Kim, J. J. What can ethobehavioral studies tell us about the Brain’s fear system. Trends Neurosci. 39, 420–431 (2016).
Google Scholar
Thorndike, E. Biological Lectures from the Marine Laboratory at Woods’ Holl, USA, for 1899. Nature 62, 411 (1900).
Bolles, R. C. Species-specific defense reactions and avoidance learning. Psychol. Rev. 77, 32–48 (1970).
Choi, J. S. & Kim, J. J. Amygdala regulates risk of predation in rats foraging in a dynamic fear environment. Proc. Natl Acad. Sci. USA 107, 21773–21777 (2010).
Google Scholar
Zambetti, P. R., Schuessler, B. P. & Kim, J. J. Sex differences in foraging rats to naturalistic aerial predator stimuli. iScience 16, 442–452 (2019).
Google Scholar
Yilmaz, M. & Meister, M. Rapid innate defensive responses of mice to looming visual stimuli. Curr. Biol. 23, 2011–2015 (2013).
Google Scholar
Papes, F., Logan, D. W. & Stowers, L. The vomeronasal organ mediates interspecies defensive behaviors through detection of protein pheromone homologs. Cell 141, 692–703 (2010).
Google Scholar
Tolman, E. C. Cognitive maps in rats and men. Psychol. Rev. 55, 189–208 (1948).
Google Scholar
Wilensky, A. E., Schafe, G. E. & LeDoux, J. E. The amygdala modulates memory consolidation of fear-motivated inhibitory avoidance learning but not classical fear conditioning. J. Neurosci. 20, 7059–7066 (2000).
Google Scholar
Lee, T. & Kim, J. J. Differential effects of cerebellar, amygdalar, and hippocampal lesions on classical eyeblink conditioning in rats. J. Neurosci. 24, 3242–3250 (2004).
Google Scholar
Stiedl, O. & Spiess, J. Effect of tone-dependent fear conditioning on heart rate and behavior of C57BL/6N mice. Behav. Neurosci. 111, 703–711 (1997).
Google Scholar
Guimaraes, F. S., Hellewell, J., Hensman, R., Wang, M. & Deakin, J. F. Characterization of a psychophysiological model of classical fear conditioning in healthy volunteers: influence of gender, instruction, personality and placebo. Psychopharmacology 104, 231–236 (1991).
Google Scholar
Mackintosh, N. J. The Psychology of Animal Learning (Academic Press, 1974).
Bouton, M. E. Learning and Behavior (Sinauer Associates 2007).
Sheafor, P. J. “Pseudoconditioned” jaw movements of the rabbit reflect associations conditioned to contextual background cues. J. Exp. Psychol. Anim. Behav. Process 1, 245–260 (1975).
Google Scholar
Rescorla, R. A. Behavioral studies of Pavlovian conditioning. Annu. Rev. Neurosci. 11, 329–352 (1988).
Google Scholar
Thompson, R. F. & Krupa, D. J. Organization of memory traces in the mammalian brain. Annu. Rev. Neurosci. 17, 519–549 (1994).
Google Scholar
Fanselow, M. S. & Wassum, K. M. The origins and organization of vertebrate pavlovian conditioning. Cold Spring Harb. Perspect. Biol. 8, a021717 (2015).
Google Scholar
Lee, H. J., Berger, S. Y., Stiedl, O., Spiess, J. & Kim, J. J. Post-training injections of catecholaminergic drugs do not modulate fear conditioning in rats and mice. Neurosci. Lett. 303, 123–126 (2001).
Google Scholar
Palgi, Y., Gelkopf, M. & Berger, R. The inoculating role of previous exposure to potentially traumatic life events on coping with prolonged exposure to rocket attacks: a lifespan perspective. Psychiatry Res. 227, 296–301 (2015).
Google Scholar
Somer, E. et al. Israeli civilians under heavy bombardment: prediction of the severity of post-traumatic symptoms. Prehosp. Disaster Med. 24, 389–394 (2009).
Google Scholar
Alexander, B. K., Beyerstein, B. L., Hadaway, P. F. & Coambs, R. B. Effect of early and later colony housing on oral ingestion of morphine in rats. Pharm. Biochem. Behav. 15, 571–576 (1981).
Google Scholar
Gage, S. H. & Sumnall, H. R. Rat Park: how a rat paradise changed the narrative of addiction. Addiction 114, 917–922 (2019).
Google Scholar
Fanselow, M. S. & Lester, L. S. A Functional Behavioristic Approach to Aversively Motivated Behavior: Predatory Imminence as a Determinant of the Topography of Defensive Behavior 185–212 (Lawrence Erlbaum Associates Inc, 1988).
Cain, C. & LeDoux, J. Brain mechanisms of Pavlovian and instrumental aversive conditioning. Handb. Behav. Neurosci. 17, 103–124 (2008).
Google Scholar
Choi, J. S., Cain, C. K. & LeDoux, J. E. The role of amygdala nuclei in the expression of auditory signaled two-way active avoidance in rats. Learn Mem. 17, 139–147 (2014).
Google Scholar
Steimer, T. The biology of fear- and anxiety-related behaviors. Dialogues Clin. Neurosci. 4, 231–249 (2002).
Google Scholar
Fanselow, M. S. The role of learning in threat imminence and defensive behaviors. Curr. Opin. Behav. Sci. 24, 44–49 (2018).
Google Scholar
Fanselow, M. S. Associative vs topographical accounts of the immediate shock freezing deficit in rats—implications for the response selection-rules governing species-specific defensive reactions. Learn. Motiv. 17, 16–39 (1986).
Google Scholar
Landeira-Fernandez, J., DeCola, J. P., Kim, J. J. & Fanselow, M. S. Immediate shock deficit in fear conditioning: effects of shock manipulations. Behav. Neurosci. 120, 873–879 (2006).
Google Scholar
Hull, C. L. A functional interpretation of the conditioned reflex. Psychol. Rev. 36, 498–511 (1929).
Google Scholar
Lazarus, A. A. Behavior Therapy and Beyond (McGraw-Hill Companies, 1971).
Öhman, A. & Mineka, S. Fears, phobias, and preparedness: toward an evolved module of fear and fear learning. Psychol. Rev. 108, 483–522 (2001).
Google Scholar
Lee, H. & Kim, J. J. Amygdalar NMDA receptors are critical for new fear learning in previously fear-conditioned rats. J. Neurosci. 18, 8444–8454 (1998).
Google Scholar
Mathis, A. et al. DeepLabCut: markerless pose estimation of user-defined body parts with deep learning. Nat. Neurosci. 21, 1281–1289 (2018).
Google Scholar
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