Haas, M., Schreiber, M. & Mascher, M. Domestication and crop evolution of wheat and barley: Genes, genomics, and future directions. J. Integr. Plant Biol. 61(3), 204–225 (2019).
Google Scholar
Hebelstrup, K. H. Differences in nutritional quality between wild and domesticated forms of barley and emmer wheat. Plant Sci. 256, 1–4 (2017).
Google Scholar
Borisjuk, N. et al. Genetic modification for wheat improvement: From transgenesis to genome editing. Biomed. Res. Int. 2019, 6216304 (2019).
Google Scholar
Maccaferri, M. et al. Durum wheat genome highlights past domestication signatures and future improvement targets. Nat. Genet. 51(5), 885–895 (2019).
Google Scholar
Brenchley, R. et al. Analysis of the bread wheat genome using whole-genome shotgun sequencing. Nature 491(7426), 705–710 (2012).
Google Scholar
Zimin, A. V. et al. The first near-complete assembly of the hexaploid bread wheat genome, Triticum aestivum. Gigascience 6(11), 1–7 (2017).
Google Scholar
Avni, R. et al. Wild emmer genome architecture and diversity elucidate wheat evolution and domestication. Science 357(6346), 93–97 (2017).
Google Scholar
Luo, M. C. et al. Genome sequence of the progenitor of the wheat D genome Aegilops tauschii. Nature 551(7681), 498–502 (2017).
Google Scholar
Jia, J. et al. Aegilops tauschii draft genome sequence reveals a gene repertoire for wheat adaptation. Nature 496(7443), 91–95 (2013).
Google Scholar
Peng, J. et al. Domestication quantitative trait loci in Triticum dicoccoides, the progenitor of wheat. Proc. Natl. Acad. Sci. U. S. A. 100(5), 2489–2494 (2003).
Google Scholar
Allen, A. M. et al. Discovery and development of exome-based, co-dominant single nucleotide polymorphism markers in hexaploid wheat (Triticum aestivum L.). Plant Biotechnol. J. 11(3), 279–295 (2013).
Google Scholar
Merchuk-Ovnat, L., Fahima, T., Krugman, T. & Saranga, Y. Ancestral QTL alleles from wild emmer wheat improve grain yield, biomass and photosynthesis across enviroinments in modern wheat. Plant Sci. 251, 23–34 (2018).
Google Scholar
Bhalla, P. L., Sharma, A. & Singh, M. B. Enabling molecular technologies for trait improvement in wheat. Methods Mol. Biol. 1679, 3–24 (2017).
Google Scholar
Hong, J., Yang, L., Zhang, D., & Shi, J. Plant metabolomics: An indispensable system biology tool for plant science. Int. J. Mol. Sci. 17(6), 1–16 (2016).
Google Scholar
Batyrshina, Z. S., Yaakov, B., Shavit, R., Singh, A. & Tzin, V. Comparative transcriptomic and metabolic analysis of wild and domesticated wheat genotypes reveals differences in chemical and physical defense responses against aphids. BMC Plant Biol. 20(1), 19 (2020).
Google Scholar
Zorb, C., Langenkamper, G., Betsche, T., Niehaus, K. & Barsch, A. Metabolite profiling of wheat grains (Triticum aestivum L.) from organic and conventional agriculture. J. Agric. Food Chem. 54(21), 8301–8306 (2006).
Google Scholar
Matthews, S. B. et al. Metabolite profiling of a diverse collection of wheat lines using ultraperformance liquid chromatography coupled with time-of-flight mass spectrometry. PLoS ONE 7(8), e44179 (2012).
Google Scholar
de Leonardis, A. M. et al. Effects of heat stress on metabolite accumulation and composition, and nutritional properties of durum wheat grain. Int. J. Mol. Sci. 16(12), 30382–30404 (2015).
Google Scholar
Allwood, J. W. et al. Profiling of spatial metabolite distributions in wheat leaves under normal and nitrate limiting conditions. Phytochemistry 115, 99–111 (2015).
Google Scholar
Ullah, N., Yuce, M., Neslihan Ozturk Gokce, Z. & Budak, H. Comparative metabolite profiling of drought stress in roots and leaves of seven Triticeae species. BMC Genom. 18(1), 969 (2017).
Google Scholar
Lannucci, A., Fragasso, M., Beleggia, R., Nigro, F. & Papa, R. Evolution of the crop rhizosphere: Impact of domestication on root exudates in tetraploid wheat (Triticum turgidum L.). Front Plant Sci. 8, 2124 (2017).
Google Scholar
Beleggia, R. et al. Evolutionary metabolomics reveals domestication-associated changes in tetraploid wheat kernels. Mol. Biol. Evol. 33(7), 1740–1753 (2016).
Google Scholar
Poudel, R., Bhinderwala, F., Morton, M., Powers, R. & Rose, D. J. Metabolic profiling of historical and modern wheat cultivars using proton nuclear magnetic resonance spectroscopy. Sci. Rep. 11(1), 3080 (2021).
Google Scholar
Hanhineva, K. et al. Non-targeted analysis of spatial metabolite composition in strawberry (Fragariaxananassa) flowers. Phytochemistry 69(13), 2463–2481 (2008).
Google Scholar
Ben-Abu, Y. & Itsko, M. “Changes in “natural antibiotic” metabolite composition during tetraploid wheat domestication. Sci. Rep. 11(1), 20340. https://doi.org/10.1038/s41598-021-98764-5 (2021).
Google Scholar
Salamini, F., Ozkan, H., Brandolini, A., Schäfer-Pregl, R. & Martin, W. Genetics and geography of wild cereal domestication in the near east. Nat. Rev. Genet. 3(6), 429–441. https://doi.org/10.1038/nrg817 (2002).
Google Scholar
Zörb, C., Langenkämper, G., Betsche, T., Niehaus, K. & Barsch, A. Metabolite profiling of wheat grains (Triticum aestivum L.) from organic and conventional agriculture. J. Agric. Food Chem. 54(21), 8301–8306 (2006).
Google Scholar
Ben-Abu, Y., Beiles, A., Flom, D. & Nevo, E. Adaptive evolution of benzoxazinoids in wild emmer wheat, Triticum dicoccoides, at “Evolution Canyon”, Mount Carmel, Israel. PLoS ONE. 13(2), e0190424 (2018).
Google Scholar
Ben-Abu, Y., et al., Durum wheat evolution—a genomic analysis. In Proceedings of the International Symposium on Genetics and Breeding of Durum Wheat, Vol. 110 29–44 (2014).
Zaynab, M. et al. Role of secondary metabolites in plant defense against pathogens. Microb. Pathog. 124, 198–202 (2018).
Google Scholar
de Bruijn, W. J. C., Gruppen, H. & Vincken, J. P. Structure and biosynthesis of benzoxazinoids: Plant defence metabolites with potential as antimicrobial scaffolds. Phytochemistry 155, 233–243 (2018).
Google Scholar
Arbona, V. & Gomez-Cadenas, A. Metabolomics of Disease resistance in crops. Mol. Biol. 19, 13–30 (2016).
Okada, K., Abe, H. & Arimura, G. Jasmonates induce both defense responses and communication in monocotyledonous and dicotyledonous plants. Plant Cell Physiol. 56(1), 16–27 (2015).
Google Scholar
Belz, R. G. Allelopathy in crop/weed interactions–an update. Pest. Manag. Sci. 63(4), 308–326 (2007).
Google Scholar
Mondal, S. et al. Harnessing diversity in wheat to enhance grain yield, climate resilience, disease and insect pest resistance and nutrition through conventional and modern breeding approaches. Front. Plant Sci. 7, 991 (2016).
Google Scholar
Huang, L. et al. Evolution and adaptation of wild emmer wheat populations to biotic and abiotic stresses. Annu. Rev. Phytopathol. 54, 279–301 (2016).
Google Scholar
Ben-David, R., Dinoor, A., Peleg, Z. & Fahima, T. Reciprocal hosts’ responses to powdery mildew isolates originating from domesticated wheats and their wild progenitor. Front. Plant Sci. 9, 75 (2018).
Google Scholar
Yahiaoui, N., Brunner, S. & Keller, B. Rapid generation of new powdery mildew resistance genes after wheat domestication. Plant J. 47(1), 85–98 (2006).
Google Scholar
Parween, T., Jan, S., Mahmooduzzafar, S., Fatma, T. & Siddiqui, Z. H. Selective effect of pesticides on plant—a review. Crit. Rev. Food Sci. Nutr. 56(1), 160–179 (2016).
Google Scholar
Mou, Y., et al. Genome-wide identification and characterization of the OPR gene family in wheat (Triticum aestivum L). Int. J. Mol. Sci. 20(8), 85–97 (2019).
Google Scholar
Kage, U., Karre, S., Kushalappa, A. C. & McCartney, C. Identification and characterization of a fusarium head blight resistance gene TaACT in wheat QTL-2DL. Plant Biotechnol. J. 15(4), 447–457 (2017).
Google Scholar
Dutartre, L., Hilliou, F. & Feyereisen, R. Phylogenomics of the benzoxazinoid biosynthetic pathway of Poaceae: Gene duplications and origin of the Bx cluster. BMC Evol. Biol. 12, 64 (2012).
Google Scholar
Gill, S. S. & Tuteja, N. Reactive oxygen species and antioxidant machinery in abiotic stress tolerance in crop plants. Plant Physiol. Biochem. 48(12), 909–930 (2010).
Google Scholar
Dhokane, D., Karre, S., Kushalappa, A. C. & McCartney, C. Integrated metabolo-transcriptomics reveals fusarium head blight candidate resistance genes in wheat QTL-Fhb2. PLoS ONE 11(5), e0155851 (2016).
Google Scholar
Kage, U., Yogendra, K. N. & Kushalappa, A. C. TaWRKY70 transcription factor in wheat QTL-2DL regulates downstream metabolite biosynthetic genes to resist Fusarium graminearum infection spread within spike. Sci. Rep. 7, 42596 (2017).
Google Scholar
Masisi, K., Beta, T. & Moghadasian, M. H. Antioxidant properties of diverse cereal grains: A review on in vitro and in vivo studies. Food Chem. 196, 90–97 (2016).
Google Scholar
Sova, M. Antioxidant and antimicrobial activities of cinnamic acid derivatives. Mini Rev. Med. Chem. 12(8), 749–767 (2012).
Google Scholar
Perez-Vizcaino, F. & Fraga, C. G. Research trends in flavonoids and health. Arch Biochem. Biophys. 646, 107–112 (2018).
Google Scholar
Kong, L., Guo, H. & Sun, M. Signal transduction during wheat grain development. Planta 241(4), 789–801 (2015).
Google Scholar
Nadolska-Orczyk, A., Rajchel, I. K., Orczyk, W. & Gasparis, S. Major genes determining yield-related traits in wheat and barley. Theor Appl Genet 130(6), 1081–1098 (2017).
Google Scholar
Li, W. & Yang, B. Translational genomics of grain size regulation in wheat. Theor. Appl. Genet. 130(9), 1765–1771 (2017).
Google Scholar
Qi, P. F. et al. Transcriptional reference map of hormone responses in wheat spikes. BMC Genom. 20(1), 390 (2019).
Google Scholar
Hill, C. B. & Li, C. Genetic architecture of flowering phenology in cereals and opportunities for crop improvement. Front .Plant Sci. 7, 1906 (2016).
Google Scholar
Jiang, Y., Schmidt, R. H., Zhao, Y. & Reif, J. C. A quantitative genetic framework highlights the role of epistatic effects for grain-yield heterosis in bread wheat. Nat. Genet. 49(12), 1741–1746 (2017).
Google Scholar
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