Davies EK, Peters AD, Keightley PD (1999) High frequency of cryptic deleterious mutations in Caenorhabditis elegans. Science 285:1748–1751
Google Scholar
Eyre-Walker A, Keightley PD (2007) The distribution of fitness effects of new mutations. Nat Rev Genet 8:610–618
Google Scholar
Eyre-Walker A, Keightley PD (2013) A comparison of models to infer the distribution of fitness effects of new mutations. Genetics 193:1197–1208
Google Scholar
Fry JD, Keightley PD, Heinsohn SL, Nuzhdi SV (1999) New estimates of the rates and effects of mildly deleterious mutation in Drosophila melanogaster. Proc Natl Acad Sci 96:574–579
Google Scholar
García-Dorado A (2007) Shortcut predictions for fitness properties at the mutation-selection-drift balance and for its buildup after size reduction under different management strategies. Genetics 176:983–997
Google Scholar
García-Dorado A (2012) Understanding and predicting the fitness decline of shrunk populations: inbreeding, purging, mutation, and standard selection. Genetics 190:1461–1476
Google Scholar
García-Dorado A (2015) On the consequences of ignoring purging on genetic recommendations for minimum viable population rules. Heredity 115:185–187
Google Scholar
García-Dorado A, Caballero A (2021) Neutral genetic diversity as a useful tool for conservation biology. Conserv Genet 22:541–545
Google Scholar
Garner BA, Hoban S, Luikart G (2020) IUCN Red List and the value of integrating genetics. Conserv Genet 21:795–801
Google Scholar
Hedrick PW, García-Dorado A (2016) Understanding inbreeding depression, purging, and genetic rescue. Trends Ecol Evol 31:940–952
Google Scholar
Kardos M, Armstrong EE, Fitzpatrick SW, Hauser S, Hedrick PW, Miller J et al. (2021) The crucial role of genome-wide genetic variation in conservation. Proc Natl Acad Sci USA 118:e2104642118
Khan A, Patel A, Shukla H, Viswanathan A, van der Valk T, Borthakur U, … & Ramakrishnan U (2021) Genomic evidence for inbreeding depression and purging of deleterious genetic variation in Indian tigers. Proc. Natl. Acad. Sci. 118
Kimura M, Maruyama T, Crow JF (1963) The mutation load in small populations. Genetics 48:1303–1312
Google Scholar
Kimura M (1980) Average time until fixation of a mutant allele in a finite population under continued mutation pressure: Studies by analytical, numerical, and pseudo-sampling methods. Proc Natl Acad Sci 77:522–526
Google Scholar
Morin PA, Archer FI, Avila CD, Balacco JR, Bukhman YV, Chow, W, … & Jarvis ED (2021) Reference genome and demographic history of the most endangered marine mammal, the vaquita. Mol Ecol Resour 21:1008–1020
Mukai T (1964) The genetic structure of natural populations of Drosophila melanogaster. I. Spontaneous mutation rate of polygenes controlling viability. Genetics 50:1–19
Google Scholar
Nietlisbach P, Muff S, Reid JM, Whitlock MC, Keller LF (2019) Nonequivalent lethal equivalents: Models and inbreeding metrics for unbiased estimation of inbreeding load. Evol Applic 12:266–279
Google Scholar
O’Grady JJ, Brook BW, Reed DH, Ballou JD, Tonkyn DW, Frankham R (2006) Realistic levels of inbreeding depression strongly affect extinction risk in wild populations. Biol Conserv 133:42–51
Google Scholar
Pérez-Pereira N, Caballero A, García-Dorado A (2021) Reviewing the consequences of genetic purging on the success of rescue programs. Conserv Gen 23:1–17
Google Scholar
Pérez-Pereira N, Wang J, Quesada H, Caballero A (2022). Prediction of the minimum effective size of a population viable in the long term. Biodivers Conserv https://doi.org/10.1007/s10531-022-02456-z
Robinson JA, Kyriazis CC, Nigenda-Morales SF, Beichman AC, Rojas-Bracho L, Robertson KM et al. (2022) The critically endangered vaquita is not doomed to extinction by inbreeding depression. Science 376:635–639
Google Scholar
Teixeira JC, Huber CD (2021) The inflated significance of neutral genetic diversity in conservation genetics. Proc Natl Acad Sci USA 118:e2015096118
Wade EE, Kyriazis C, Cavassim MIA, Lohmueller KE (2022) Quantifying the fraction of new mutations that are recessive lethal. bioRxiv 1–24, https://www.biorxiv.org/content/10.1101/2022.04.22.489225v1
Source: Ecology - nature.com
