in

Catestatin selects for colonization of antimicrobial-resistant gut bacterial communities

  • Kåhrström CT, Pariente N, Weiss U. Intestinal microbiota in health and disease. Nature 2016;535:47–47.

    Article 

    Google Scholar 

  • El Aidy S, van Baarlen P, Derrien M, Lindenbergh-Kortleve DJ, Hooiveld G, Levenez F, et al. Temporal and spatial interplay of microbiota and intestinal mucosa drive establishment of immune homeostasis in conventionalized mice. Mucosal Immunol. 2012;5:567–79.

    CAS 
    Article 

    Google Scholar 

  • Okumura R, Takeda K. Roles of intestinal epithelial cells in the maintenance of gut homeostasis. Exp Mol Med. 2017;49:e338–e338.

    CAS 
    Article 

    Google Scholar 

  • Mahata SK, O’Connor DT, Mahata M, Yoo SH, Taupenot L, Wu H, et al. Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist. J Clin Invest. 1997;100:1623–33.

    CAS 
    Article 

    Google Scholar 

  • Briolat J, Wu SD, Mahata SK, Gonthier B, Bagnard D, Chasserot-Golaz S, et al. New antimicrobial activity for the catecholamine release-inhibitory peptide from chromogranin A. Cell Mol Life Sci. 2005;62:377–85.

    CAS 
    Article 

    Google Scholar 

  • Lugardon K, Raffner R, Goumon Y, Corti A, Delmas A, Bulet P, et al. Antibacterial and antifungal activities of vasostatin-1, the N-terminal fragment of chromogranin A. J Biol Chem. 2000;275:10745–53.

    CAS 
    Article 

    Google Scholar 

  • Aslam R, Atindehou M, Lavaux T, Haïkel Y, Schneider F, Metz-Boutigue M-H. Chromogranin A-derived peptides are involved in innate immunity. Curr Med Chem. 2012;19:4115–23.

    CAS 
    Article 

    Google Scholar 

  • El-Salhy M, Patcharatrakul T, Hatlebakk JG, Hausken T, Gilja OH, Gonlachanvit S. Chromogranin A cell density in the large intestine of Asian and European patients with irritable bowel syndrome. Scand J Gastroenterol. 2017;52:691–7.

    CAS 
    Article 

    Google Scholar 

  • Bartolomucci A, Possenti R, Mahata SK, Fischer-Colbrie R, Loh YP, Salton SR. The extended granin family: structure, function, and biomedical implications. Endocr Rev. 2011;32:755–97.

    CAS 
    Article 

    Google Scholar 

  • Mahata SK, Corti A. Chromogranin A and its fragments in cardiovascular, immunometabolic, and cancer regulation. Ann N Y Acad Sci. 2019;1455:34–58.

    CAS 
    Article 

    Google Scholar 

  • Corti A, Marcucci F, Bachetti T. Circulating chromogranin A and its fragments as diagnostic and prognostic disease markers. Pflugers Archiv Eur J Physiol. 2018;470:199–210.

  • Mahata SK, Mahata M, Fung MM, O’Connor DT. Catestatin: a multifunctional peptide from chromogranin A. Regul Pept. 2010;162:33–43.

    CAS 
    Article 

    Google Scholar 

  • Ying W, Mahata S, Bandyopadhyay GK, Zhou Z, Wollam J, Vu J, et al. Catestatin inhibits obesity-induced macrophage infiltration and inflammation in the liver and suppresses hepatic glucose production, leading to improved insulin sensitivity. Diabetes. 2018;67:841–8.

    CAS 
    Article 

    Google Scholar 

  • Mahata SK, Kiranmayi M, Mahapatra NR. Catestatin: a master regulator of cardiovascular functions. Curr Med Chem. 2018;25:1352–74.

    CAS 
    Article 

    Google Scholar 

  • Muntjewerff EM, Tang K, Lutter L, Christoffersson G, Nicolasen MJT, Gao H, et al. Chromogranin A regulates gut permeability via the antagonistic actions of its proteolytic peptides. Acta Physiol. 2021;232:e13655.

  • Rabbi MF, Munyaka PM, Eissa N, Metz-Boutigue MH, Khafipour E, Ghia JE. Human catestatin alters gut microbiota composition in mice. Front Microbiol. 2017;7:1–12.

    Article 

    Google Scholar 

  • Radek KA, Lopez-Garcia B, Hupe M, Niesman IR, Elias PM, Taupenot L, et al. The neuroendocrine peptide catestatin is a cutaneous antimicrobial and induced in the skin after injury. J Invest Dermatol. 2008;128:1525–34.

    CAS 
    Article 

    Google Scholar 

  • Bevins CL, Salzman NH. Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis. Nat Rev Microbiol. 2011;9:356–68.

    CAS 
    Article 

    Google Scholar 

  • Dupont A, Heinbockel L, Brandenburg K, Hornef MW. Antimicrobial peptides and the enteric mucus layer act in concert to protect the intestinal mucosa. Gut Microbes. 2014;5:761–5.

    Article 

    Google Scholar 

  • Tsukuda N, Yahagi K, Hara T, Watanabe Y, Matsumoto H, Mori H, et al. Key bacterial taxa and metabolic pathways affecting gut short-chain fatty acid profiles in early life. ISME J. 2021;15:2574–90.

    CAS 
    Article 

    Google Scholar 

  • Nuri R, Shprung T, Shai Y. Defensive remodeling: How bacterial surface properties and biofilm formation promote resistance to antimicrobial peptides. Biochim Biophys Acta Biomembr. 2015;1848:3089–100.

    CAS 
    Article 

    Google Scholar 

  • Jakobsson HE, Rodríguez‐Piñeiro AM, Schütte A, Ermund A, Boysen P, Bemark M, et al. The composition of the gut microbiota shapes the colon mucus barrier. EMBO Rep. 2015;16:164–77.

    CAS 
    Article 

    Google Scholar 

  • Samantha A, Vrielink A. Lipid A Phosphoethanolamine Transferase: regulation, structure and immune response. J Mol Biol. 2020;432:5184–96.

    CAS 
    Article 

    Google Scholar 

  • Gottesman S. Proteases and their targets in Escherichia coli. Annu Rev Genet. 1996;30:465–506.

    CAS 
    Article 

    Google Scholar 

  • Mirsepasi-Lauridsen HC, Vallance BA, Krogfelt KA, Petersen AM. Escherichia coli pathobionts associated with inflammatory bowel disease. Clin Microbiol Rev. 2019;32:1–16.

    Article 

    Google Scholar 

  • Nayfach S, Fischbach MA, Pollard KS. MetaQuery: a web server for rapid annotation and quantitative analysis of specific genes in the human gut microbiome. Bioinformatics. 2015;31:3368–70.

    CAS 
    Article 

    Google Scholar 

  • Ying W, Tang K, Avolio E, Schilling JM, Pasqua T, Liu MA, et al. Immunosuppression of macrophages underlies the cardioprotective effects of CST (Catestatin). Hypertension. 2021;77:1670–82.

    CAS 
    Article 

    Google Scholar 

  • Stojanov S, Berlec A, Štrukelj B. The influence of probiotics on the firmicutes/bacteroidetes ratio in the treatment of obesity and inflammatory bowel disease. Microorganisms. 2020;8:1–16.

    Article 

    Google Scholar 

  • Indiani CMDSP, Rizzardi KF, Castelo PM, Ferraz LFC, Darrieux M, Parisotto TM. Childhood obesity and firmicutes/bacteroidetes ratio in the gut microbiota: a systematic review. Child Obes. 2018;14:501–9.

    Article 

    Google Scholar 

  • Lam YY, Ha CWY, Campbell CR, Mitchell AJ, Dinudom A, Oscarsson J, et al. Increased gut permeability and microbiota change associate with mesenteric fat inflammation and metabolic dysfunction in diet-induced obese mice. PLoS One. 2012;7:1–10.

    Google Scholar 

  • Herp S, Durai Raj AC, Salvado Silva M, Woelfel S, Stecher B. The human symbiont Mucispirillum schaedleri: causality in health and disease. Med Microbiol Immunol. 2021;210:173–9.

    Article 

    Google Scholar 

  • Parker BJ, Wearsch PA, Veloo ACM, Rodriguez-Palacios A. The genus alistipes: gut bacteria with emerging implications to inflammation, cancer, and mental health. Front Immunol. 2020;11:1–15.

    Article 

    Google Scholar 

  • Hiippala K, Barreto G, Burrello C, Diaz-Basabe A, Suutarinen M, Kainulainen V, et al. Novel Odoribacter splanchnicus strain and its outer membrane vesicles exert immunoregulatory effects in vitro. Front Microbiol. 2020;11:1–14.

    Article 

    Google Scholar 

  • McPhee JB, Small CL, Reid-Yu SA, Brannon JR, Moual H LE, Coombes BK. Host defense peptide resistance contributes to colonization and maximal intestinal pathology by Crohn’s disease-associated adherent-invasive Escherichia coli. Infect Immun. 2014;82:3383–93.

    Article 

    Google Scholar 

  • Xu Y, Wei W, Lei S, Lin J, Srinivas S, Feng Y. An evolutionarily conserved mechanism for intrinsic and transferable polymyxin resistance. MBio. 2018;9:1–18.

    Article 

    Google Scholar 

  • Thomassin JL, Brannon JR, Gibbs BF, Gruenheid S, Le Moual H. OmpT outer membrane proteases of enterohemorrhagic and enteropathogenic Escherichia coli contribute differently to the degradation of human LL-37. Infect Immun. 2012;80:483–92.

    CAS 
    Article 

    Google Scholar 

  • Desloges I, Taylor JA, Leclerc JM, Brannon JR, Portt A, Spencer JD, et al. Identification and characterization of OmpT-like proteases in uropathogenic Escherichia coli clinical isolates. Microbiologyopen. 2019;8:1–36.

    Article 

    Google Scholar 

  • McCarter JD, Stephens D, Shoemaker K, Rosenberg S, Kirsch JF, Georgiou G. Substrate specificity of the Escherichia coli outer membrane protease OmpT. J Bacteriol. 2004;186:5919–25.

    CAS 
    Article 

    Google Scholar 

  • Kulkarni HM, Nagaraj R, Jagannadham MV. Protective role of E. coli outer membrane vesicles against antibiotics. Microbiol Res. 2015;181:1–7.

    CAS 
    Article 

    Google Scholar 

  • Muntjewerff EM, Dunkel G, Nicolasen MJT, Mahata SK, van den Bogaart G. Catestatin as a Target for Treatment of Inflammatory Diseases. Front Immunol. 2018;9:2199.

  • Santella RM. Approaches to DNA/RNA extraction and whole genome amplification: table 1. Cancer Epidemiol Biomark Prev. 2006;15:1585–7.

    CAS 
    Article 

    Google Scholar 

  • Callahan BJ, McMurdie PJ, Rosen MJ, Han AW, Johnson AJA, Holmes SP. DADA2: high-resolution sample inference from Illumina amplicon data. Nat Methods. 2016;13:581–3.

    CAS 
    Article 

    Google Scholar 

  • R Core Team. R: a language and environment for statistical computing. Vienna, Austria; 2019. https://www.r-project.org/.

  • Lahti L, Shetty S. microbiome R package. http://microbiome.github.io.

  • McMurdie PJ, Holmes S. Phyloseq: an R package for reproducible interactive analysis and graphics of microbiome census data. PLoS One. 2013;8:e61217.

  • Paulson JN, Colin Stine O, Bravo HC, Pop M. Differential abundance analysis for microbial marker-gene surveys. Nat Methods. 2013;10:1200–2.

    CAS 
    Article 

    Google Scholar 

  • Segata N, Izard J, Waldron L, Gevers D, Miropolsky L, Garrett WS, et al. Metagenomic biomarker discovery and explanation. Genome Biol. 2011;12:R60.

    Article 

    Google Scholar 

  • Douglas GM, Maffei VJ, Zaneveld JR, Yurgel SN, Brown JR, Taylor CM, et al. PICRUSt2 for prediction of metagenome functions. Nat Biotechnol. 2020;38:685–8.

    CAS 
    Article 

    Google Scholar 

  • Parks DH, Tyson GW, Hugenholtz P, Beiko RG. STAMP: Statistical analysis of taxonomic and functional profiles. Bioinformatics. 2014;30:3123–4.

    CAS 
    Article 

    Google Scholar 

  • Beresford-Jones BS, Forster SC, Stares MD, Notley G, Viciani E, Browne HP, et al. The Mouse Gastrointestinal Bacteria Catalogue enables translation between the mouse and human gut microbiotas via functional mapping. Cell Host Microbe. 2022;30:124–138.e8.

    CAS 
    Article 

    Google Scholar 

  • Katoh K, Standley DM. MAFFT multiple sequence alignment software version 7: Improvements in performance and usability. Mol Biol Evol. 2013;30:772–80.

    CAS 
    Article 

    Google Scholar 

  • Price MN, Dehal PS, Arkin AP. FastTree 2 – approximately maximum-likelihood trees for large alignments. PLoS One. 2010;5:e9490.

    Article 

    Google Scholar 

  • Menardo F, Loiseau C, Brites D, Coscolla M, Gygli SM, Rutaihwa LK, et al. Treemmer: a tool to reduce large phylogenetic datasets with minimal loss of diversity. BMC Bioinforma. 2018;19:1–8.

    Article 

    Google Scholar 

  • Haider SR, Reid HJ, Sharp BL. Tricine-SDS-PAGE. In: Kurien B., Scofield R. editors. Protein electrophoresis. Methods in Molecular Biology (Methods and Protocols). Totowa, NJ: Humana Press; 2012. p. 81–91.

  • Schägger H. Tricine-SDS-PAGE. Nat Protoc. 2006;1:16–22.

    Article 

    Google Scholar 

  • Zoetendal EG, Booijink CCGM, Klaassens ES, Heilig HGHJ, Kleerebezem M, Smidt H, et al. Isolation of RNA from bacterial samples of the human gastrointestinal tract. Nat Protoc. 2006;1:954–9.

    CAS 
    Article 

    Google Scholar 

  • Zhou K, Zhou L, Lim Q, Zou R, Stephanopoulos G, Too HP. Novel reference genes for quantifying transcriptional responses of Escherichia coli to protein overexpression by quantitative PCR. BMC Mol Biol. 2011;12:18.

    CAS 
    Article 

    Google Scholar 

  • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔCT method. Methods. 2001;25:402–8.

    CAS 
    Article 

    Google Scholar 


  • Source: Ecology - nature.com

    Punishment institutions selected and sustained through voting and learning

    MIT engineers introduce the Oreometer