Minnis, A. M. & Lindner, D. L. Phylogenetic evaluation of geomyces and allies reveals no close relatives of Pseudogymnoascus destructans, comb. Nov., in bat hibernacula of eastern North America. Fungal Biol. 117, 638–649 (2013).
Blehert, D. S. et al. Bat white-nose syndrome: An emerging fungal pathogen?. Science 323, 227. https://doi.org/10.1126/science.1163874 (2009).
Chaturvedi, V. & Chaturvedi, S. Editorial: What is in a Name? A proposal to use geomycosis instead of white nose syndrome (WNS) to describe bat infection caused by geomyces destructans. Mycopathologia 171, 231–233. https://doi.org/10.1007/s11046-010-9385-3 (2011).
Frick, W. F., Puechmaille, S. J. & Willis, C. K. Bats in the Anthropocene: Conservation of Bats in a Changing World 245–262 (Springer, Berlin, 2016).
Bandouchova, H. et al. Alterations in the health of hibernating bats under pathogen pressure. Sci. Rep. 8, 6067 (2018).
Zukal, J. et al. White-nose syndrome without borders: Pseudogymnoascus destructans infection tolerated in Europe and Palearctic Asia but not in North America. Sci. Rep. 6, 19829 (2016).
Drees, K. P. et al. Phylogenetics of a fungal invasion: Origins and widespread dispersal of white-nose syndrome. mBio 8, 11941–11917 (2017).
Leopardi, S., Blake, D. & Puechmaille, S. J. White-nose syndrome fungus introduced from Europe to North America. Curr. Biol. 25, 217–219 (2015).
Palmer, J. M. et al. Molecular characterization of a heterothallic mating system in Pseudogymnoascus destructans, the fungus causing white-nose syndrome of bats. G3 Genes Genomes Genet. 4, 1755–1763 (2014).
Trivedi, J. N. Population genomics and mutational history of the invasive, epidemic clone of Pseudogymnoascus destructans, causal agent of White-nose Syndrome in bats (University of Toronto, Toronto, 2017).
Rajkumar, S. S. et al. Clonal genotype of Geomyces destructans among bats with white nose syndrome, New York, USA. Emerg. Infect. Dis 17, 1273–1276 (2011).
Lorch, J. M. et al. First detection of bat white-nose syndrome in western North America. mSphere 1, e00148-e1116 (2016).
Forsythe, A., Giglio, V., Asa, J. & Xu, J. Phenotypic divergence along geographic gradients reveals potential for rapid adaptation of the White-nose syndrome pathogen, Pseudogymnoascus destructans, North America. Appl. Environ. Microbiol. 84, e00863-e1818. https://doi.org/10.1128/aem.00863-18 (2018).
Khankhet, J. et al. Clonal expansion of the Pseudogymnoascus destructans genotype in North America is accompanied by significant variation in phenotypic expression. PLoS ONE 9, e104684 (2014).
Cryan, P. M., Meteyer, C. U., Boyles, J. G. & Blehert, D. S. Wing pathology of white-nose syndrome in bats suggests life-threatening disruption of physiology. BMC Biol. 8, 1–8. https://doi.org/10.1186/1741-7007-8-135 (2010).
Meteyer, C. U. et al. Histopathologic criteria to confirm white-nose syndrome in bats. J. Vet. Diagn. Invest. 21, 411–414. https://doi.org/10.1177/104063870902100401 (2009).
Pikula, J. et al. White-nose syndrome pathology grading in nearctic and palearctic bats. PLoS ONE 12, e0180435 (2017).
Warnecke, L. et al. Inoculation of bats with European Geomyces destructans supports the novel pathogen hypothesis for the origin of white-nose syndrome. Proc. Natl. Acad. Sci. 109, 6999–7003 (2012).
Flieger, M. et al. Vitamin B2 as a virulence factor in Pseudogymnoascus destructans skin infection. Sci. Rep. 6, 33200 (2016).
Hayman, D. T. S., Pulliam, J. R. C., Marshall, J. C., Cryan, P. M. & Webb, C. T. Environment, host, and fungal traits predict continental-scale white-nose syndrome in bats. Sci. Adv. 2, e1500831. https://doi.org/10.1126/sciadv.1500831 (2016).
Warnecke, L. et al. Pathophysiology of white-nose syndrome in bats: A mechanistic model linking wing damage to mortality. Vol. 9 (2013).
Wibbelt, G. in Emerging and Epizootic Fungal Infections in Animals 289–307 (Springer, Berlin, 2018).
Achterman, R. R. & White, T. C. Dermatophyte virulence factors: Identifying and analyzing genes that may contribute to chronic or acute skin infections. Int. J. Microbiol. 20, 12 (2011).
Chinnapun, D. Virulence factors involved in pathogenicity of dermatophytes. Walailak J. Sci. Technol. (WJST) 12, 573–580 (2015).
Pannkuk, E. L., Risch, T. S. & Savary, B. J. Isolation and identification of an extracellular subtilisin-like serine protease secreted by the bat pathogen Pseudogymnoascus destructans. PLoS ONE 10, e0120508. https://doi.org/10.1371/journal.pone.0120508 (2015).
Raudabaugh, D. B. & Miller, A. N. Nutritional capability of and substrate suitability for Pseudogymnoascus destructans, the causal agent of bat white-nose syndrome. PLoS ONE 8, e78300. https://doi.org/10.1371/journal.pone.0078300 (2013).
Mascuch, S. J. et al. Direct detection of fungal siderophores on bats with white-nose syndrome via fluorescence microscopy-guided ambient ionization mass spectrometry. PLoS ONE 10, e0119668. https://doi.org/10.1371/journal.pone.0119668 (2015).
van Burik, J. A. H. & Magee, P. T. Aspects of fungal pathogenesis in humans. Annu. Rev. Microbiol. 55, 743–772 (2001).
Donaldson, M. E. et al. Growth medium and incubation temperature alter the Pseudogymnoascus destructans transcriptome: Implications in identifying virulence factors. Mycologia 110, 300–315 (2018).
Field, K. A. et al. The white-nose syndrome transcriptome: activation of anti-fungal host responses in wing tissue of hibernating little brown Myotis. PLoS Pathog. 11, e1005168. https://doi.org/10.1371/journal.ppat.1005168 (2015).
Reeder, S. M. et al. Pseudogymnoascus destructans transcriptome changes during white-nose syndrome infections. Virulence 8, 1695–1707 (2017).
Lorch, J. M. et al. Experimental infection of bats with Geomyces destructans causes white-nose syndrome. Nature 480, 376 (2011).
Lorch, J. M. et al. A culture-based survey of fungi in soil from bat hibernacula in the eastern United States and its implications for detection of Geomyces destructans, the causal agent of bat white-nose syndrome. Mycologia 105, 237–252. https://doi.org/10.3852/12-207 (2012).
Meyer, A. D., Stevens, D. F. & Blackwood, J. C. Predicting bat colony survival under controls targeting multiple transmission routes of white-nose syndrome. J. Theor. Biol. 409, 60–69 (2016).
Gargas, A., Trest, M., Christensen, M., Volk, T. J. & Blehert, D. Geomyces destructans sp. nov. associated with bat white-nose syndrome. Mycotaxon 108, 147–154 (2009).
Chaturvedi, V. et al. Morphological and molecular characterizations of psychrophilic fungus Geomyces destructans from New York bats with white nose syndrome (WNS). PLoS ONE 5, e10783 (2010).
Verant, M. L., Boyles, J. G., Waldrep, W. Jr., Wibbelt, G. & Blehert, D. S. Temperature-dependent growth of Geomyces destructans, the fungus that causes bat white-nose syndrome. PLoS ONE 7, e46280 (2012).
Palmer, J. M., Drees, K. P., Foster, J. T. & Lindner, D. L. Extreme sensitivity to ultraviolet light in the fungal pathogen causing white-nose syndrome of bats. Nat. Commun. 9, 35. https://doi.org/10.1038/s41467-017-02441-z (2018).
Campbell, L. J., Walsh, D. P., Blehert, D. S. & Lorch, J. M. Long-term survival of Pseudogymnoascus destructans at elevated temperatures. J. Wildlife Dis. 56, 278–287 (2020).
Reynolds, H. T. & Barton, H. A. Comparison of the white-nose syndrome agent Pseudogymnoascus destructans to cave-dwelling relatives suggests reduced saprotrophic enzyme activity. PLoS ONE 9, e86437. https://doi.org/10.1371/journal.pone.0086437 (2014).
Smyth, C., Schlesinger, S., Overton, B. & Butchkoski, C. The alternative host hypothesis and potential virulence genes in Geomyces destructans. Bat Res. News 54, 17–24 (2013).
Chaturvedi, V., DeFiglio, H. & Chaturvedi, S. Phenotype profiling of white-nose syndrome pathogen Pseudogymnoascus destructans and closely-related Pseudogymnoascus pannorum reveals metabolic differences underlying fungal lifestyles. F1000Research 7, 2 (2018).
Vanderwolf, K. J., Malloch, D., McAlpine, D. F. & Forbes, G. J. A world review of fungi, yeasts, and slime molds in caves. Int. J. Speleol. 42, 9 (2013).
Wilson, M. B., Held, B. W., Freiborg, A. H., Blanchette, R. A. & Salomon, C. E. Resource capture and competitive ability of non-pathogenic Pseudogymnoascus spp. and P. destructans, the cause of white-nose syndrome in bats. PLoS ONE 12, e0178968. https://doi.org/10.1371/journal.pone.0178968 (2017).
Gabriel, K. T., Neville, J. J., Pierce, G. E. & Cornelison, C. T. Lipolytic activity and the utilization of fatty acids associated with bat sebum by Pseudogymnoascus destructans. Mycopathologia 184, 625–636. https://doi.org/10.1007/s11046-019-00381-4 (2019).
Park, M., Do, E. & Jung, W. H. Lipolytic enzymes involved in the virulence of human pathogenic fungi. Mycobiology 41, 67–72. https://doi.org/10.5941/myco.2013.41.2.67 (2013).
Carlini, C. R. & Ligabue-Braun, R. Ureases as multifunctional toxic proteins: A review. Toxicon 110, 90–109 (2016).
Cox, G. M., Mukherjee, J., Cole, G. T., Casadevall, A. & Perfect, J. R. Urease as a virulence factor in experimental cryptococcosis. Infect. Immun. 68, 443–448 (2000).
Vylkova, S. & Lorenz, M. C. Modulation of phagosomal pH by Candida albicans promotes hyphal morphogenesis and requires Stp2p, a regulator of amino acid transport. PLoS Pathog. 10, e1003995. https://doi.org/10.1371/journal.ppat.1003995 (2014).
Vylkova, S. Environmental pH modulation by pathogenic fungi as a strategy to conquer the host. PLoS Pathog. 13, e1006149. https://doi.org/10.1371/journal.ppat.1006149 (2017).
Shawcross, D. L. et al. Ammonia impairs neutrophil phagocytic function in liver disease. Hepatology 48, 1202–1212 (2008).
O’Donoghue, A. J. et al. Destructin-1 is a collagen-degrading endopeptidase secreted by Pseudogymnoascus destructans, the causative agent of white-nose syndrome. PNAS 112, 7478–7483. https://doi.org/10.1073/pnas.1507082112 (2015).
Marroquin, C. M., Lavine, J. O. & Windstam, S. T. Effect of humidity on development of Pseudogymnoascus destructans, the causal agent of bat white-nose syndrome. Northeastern Nat. 24, 54–64 (2017).
Kolařík, M. et al. Geosmithia associated with bark beetles and woodborers in the western USA: Taxonomic diversity and vector specificity. Mycologia 109, 185–199. https://doi.org/10.1080/00275514.2017.1303861 (2017).
Garland, J. L. Analytical approaches to the characterization of samples of microbial communities using patterns of potential C source utilization. Soil Biol. Biochem. 28, 213–221. https://doi.org/10.1016/0038-0717(95)00112-3 (1996).
Dobranic, J. K. & Zak, J. C. A microtiter plate procedure for evaluating fungal functional diversity. Mycologia 91, 756–765 (1999).
Harch, B. D., Correll, R. L., Meech, W., Kirkby, C. A. & Pankhurst, C. E. Using the Gini coefficient with BIOLOG substrate utilisation data to provide an alternative quantitative measure for comparing bacterial soil communities. J. Microbiol. Methods 30, 91–101. https://doi.org/10.1016/s0167-7012(97)00048-1 (1997).
Sobek, E. A. & Zak, J. C. The Soil FungiLog procedure: Method and analytical approaches toward understanding fungal functional diversity. Mycologia 95, 590–602 (2003).
Kouker, G. & Jaeger, K.-E. Specific and sensitive plate assay for bacterial lipases. Appl. Environ. Microbiol. 53, 211–213 (1987).
Lupan, D. M. & Nziramasanga, P. Collagenolytic activity of Coccidioides immitis. Infect. Immun. 51, 360–361 (1986).
Saleh-Rastin, N., Petersen, M., Coleman, S. & Hubbell, D. The rhizosphere and plant growth 188–188 (Springer, Berlin, 1991).
NziramasangaM, P. & Lupan, D. Elastase activity of Coccidioides immitis. J. Med. Microbiol. 19, 109–114 (1985).
Dietz, M. & Kalko, E. K. Seasonal changes in daily torpor patterns of free-ranging female and male Daubenton’s bats (Myotis daubentonii). J. Comp. Physiol. B. 176, 223–231 (2006).
Sephton-Clark, P. C. S. & Voelz, K. In Advances in applied microbiology (eds Sima, S. & Geoffrey, M. G.) 117–157 (Academic Press, New York, 2018).
Hammer, O., Harper, D. A. T. & Ryan, P. D. PAST: Paleontological statistics software package for education and data analysis. Palaeontol. Electron. 4, 1–9 (2001).
Martínková, N. et al. Increasing incidence of Geomyces destructans fungus in bats from the Czech Republic and Slovakia. PLoS ONE 5, e13853 (2010).
Větrovský, T., Kolařík, M., Žifčáková, L., Zelenka, T. & Baldrian, P. The rpb2 gene represents a viable alternative molecular marker for the analysis of environmental fungal communities. Mol. Ecol. Resour. 16, 388–401 (2016).
Crous, P. et al. Fungal planet description sheets: 558–624. Persoonia 38, 240 (2017).
Hubka, V. et al. A reappraisal of Aspergillus section Nidulantes with descriptions of two new sterigmatocystin-producing species. Plant Syst. Evol. 302, 1267–1299 (2016).
Kubátová, A., Hujslová, M., Frisvad, J. C., Chudíčková, M. & Kolařík, M. Taxonomic revision of the biotechnologically important species Penicillium oxalicum with the description of two new species from acidic and saline soils. Mycol. Progr. 18, 215–228 (2019).
Gabrielová, A. et al. The oomycete Pythium oligandrum can suppress and kill the causative agents of dermatophytoses. Mycopathologia 183, 751–764 (2018).
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