Validation of SNP markers for thermotolerance adaptation in Ovis aries adapted to different climatic regions using KASP-PCR technique
IPCC. Summary for Policymakers. In (Masson-Delmotte, V., P. Zhai, H.-O. Pörtner, D. Roberts, J. Skea, P.R. Shukla, A. Pirani, W. Moufouma-Okia, C. Péan, R. Pidcock, S. Connors, J.B.R. Matthews, Y. Chen, X. Zhou, M.I. Gomis, E. Lonnoy, T. Maycock, M. Tignor, and T. Waterfield, eds) Global Warming of 1.5°C. An IPCC Special Report on the impacts of global warming of 1.5°C above pre-industrial levels and related global greenhouse gas emission pathways, in the context of strengthening the global response to the threat of climate change, sustainable development, and efforts to eradicate poverty. In Press (2018).Malhi, Y. et al. Climate change and ecosystems: Threats, opportunities and solutions. Philos. Trans. R. Soc. B Biol. Sci. 375(1794), 20190104. https://doi.org/10.1098/rstb.2019.0104 (2020).Article
CAS
Google Scholar
McElwee, P. Climate change and biodiversity loss. Curr. Hist. 120(829), 295–300. https://doi.org/10.1525/curh.2021.120.829.295 (2021).Article
Google Scholar
Dickinson, M. G., Orme, C. D. L., Suttle, K. B. & Mace, G. M. Separating sensitivity from exposure in assessing extinction risk from climate change. Sci. Rep. 4(1), 6898. https://doi.org/10.1038/srep06898 (2015).Article
CAS
Google Scholar
UNFCCC (United Nations Framework Convention on Climate Change). Global Warming Potentials http://unfccc.int/ghg_data/items/3825.php (2014).BelhadjSlimen, I., Chniter, M., Najar, T. & Ghram, A. Meta-analysis of some physiologic, metabolic and oxidative responses of sheep exposed to environmental heat stress. Livestock Sci. 229, 179–187. https://doi.org/10.1016/j.livsci.2019.09.026 (2019).Article
Google Scholar
Wojtas, K., Cwynar, P. & Kołacz, R. Effect of thermal stress on physiological and blood parameters in merino sheep. Bull. Vet. Inst. Pulawy 58(2), 283–288. https://doi.org/10.2478/bvip-2014-0043 (2014).Article
Google Scholar
Gavojdian, D., Cziszter, L. T., Budai, C. & Kusza, S. Effects of behavioral reactivity on production and reproduction traits in Dorper sheep breed. J. Vet. Behav. 10(4), 365–368. https://doi.org/10.1016/j.jveb.2015.03.012 (2015).Article
Google Scholar
Mehaba, N., Coloma-Garcia, W., Such, X., Caja, G. & Salama, A. A. K. Heat stress affects some physiological and productive variables and alters metabolism in dairy ewes. J. Dairy Sci. 104(1), 1099–1110. https://doi.org/10.3168/jds.2020-18943 (2021).Article
CAS
Google Scholar
Ramón, M., Díaz, C., Pérez-Guzman, M. D. & Carabaño, M. J. Effect of exposure to adverse climatic conditions on production in Manchega dairy sheep. J. Dairy Sci. 99(7), 5764–6577. https://doi.org/10.3168/jds.2016-10909 (2016).Article
CAS
Google Scholar
Mahjoubi, E. et al. The effect of cyclical and severe heat stress on growth performance and metabolism in Afshari lambs1. J. Anim. Sci. 93(4), 1632–1640. https://doi.org/10.2527/jas.2014-8641 (2015).Article
CAS
Google Scholar
dos Hamilton, T. R. S. et al. Evaluation of lasting effects of heat stress on sperm profile and oxidative status of ram semen and epididymal sperm. Oxid. Med. Cell. Longev. 1–12, 2016. https://doi.org/10.1155/2016/1687657 (2016).Article
CAS
Google Scholar
Romo-Barron, C. B. et al. Impact of heat stress on the reproductive performance and physiology of ewes: A systematic review and meta-analyses. Int. J. Biometeorol. 63(7), 949–962. https://doi.org/10.1007/s00484-019-01707-z (2019).Article
ADS
Google Scholar
Caroprese, M. et al. Glucocorticoid effects on sheep peripheral blood mononuclear cell proliferation and cytokine production under in vitro hyperthermia. J. Dairy Sci. 101(9), 8544–8551. https://doi.org/10.3168/jds.2018-14471 (2018).Article
CAS
Google Scholar
Marcone, G., Kaart, T., Piirsalu, P. & Arney, D. R. Panting scores as a measure of heat stress evaluation in sheep with access and with no access to shade. Appl. Anim. Behav. Sci. 240, 105350. https://doi.org/10.1016/j.applanim.2021.105350 (2021).Article
Google Scholar
Van Wettere, W. H. E. J. et al. Review of the impact of heat stress on reproductive performance of sheep. J. Anim. Sci. Biotechnol. 12(1), 26. https://doi.org/10.1186/s40104-020-00537-z (2021).Article
Google Scholar
Belhadj Slimen, I., Najar, T., Ghram, A. & Abdrrabba, M. Heat stress effects on livestock: Molecular, cellular and metabolic aspects, a review. J. Anim. Physiol. Anim. Nutr. 100(3), 401–412. https://doi.org/10.1111/jpn.12379 (2016).Article
CAS
Google Scholar
Guo, Z., Gao, S., Ouyang, J., Ma, L. & Bu, D. Impacts of heat stress-induced oxidative stress on the milk protein biosynthesis of dairy cows. Animals 11(3), 726. https://doi.org/10.3390/ani11030726 (2021).Article
Google Scholar
Liu, Z. et al. Heat stress in dairy cattle alters lipid composition of milk. Sci. Rep. 7(1), 961. https://doi.org/10.1038/s41598-017-01120-9 (2017).Article
ADS
CAS
Google Scholar
Krishnan, G. et al. Mitigation of the heat stress impact in Livestock reproduction. In Theriogenology (InTech, 2017).
Google Scholar
Robertson, S. & Friend, M. Strategies to ameliorate heat stress effects on sheep reproduction. In Climate Change and Livestock Production: Recent Advances and Future Perspectives 175–183 (Springer, 2021). https://doi.org/10.1007/978-981-16-9836-1_15.Chapter
Google Scholar
Sawyer, G. & Narayan, E. J. A review on the influence of climate change on sheep reproduction. In Comparative Endocrinology of Animals (Intech Open, 2019). https://doi.org/10.5772/intechopen.86799.Chapter
Google Scholar
Maurya, V. P., Sejian, V., Kumar, D. & Naqvi, S. M. K. Biological ability of Malpura rams to counter heat stress challenges and its consequences on production performance in a semi-arid tropical environment. Biol. Rhythm. Res. 49(3), 479–493. https://doi.org/10.1080/09291016.2017.1381451 (2018).Article
Google Scholar
Shahat, A. M., Rizzoto, G. & Kastelic, J. P. Amelioration of heat stress-induced damage to testes and sperm quality. Theriogenology 158, 84–96. https://doi.org/10.1016/j.theriogenology.2020.08.034 (2020).Article
CAS
Google Scholar
Singh, K. M. et al. Association of heat stress protein 90 and 70 gene polymorphism with adaptability traits in Indian sheep (Ovis aries). Cell Stress Chaperones 22(5), 675–684. https://doi.org/10.1007/s12192-017-0770-4 (2017).Article
CAS
Google Scholar
Kim, E.-S. et al. Multiple genomic signatures of selection in goats and sheep indigenous to a hot arid environment. Heredity 116(3), 255–264. https://doi.org/10.1038/hdy.2015.94 (2016).Article
CAS
Google Scholar
do Paim, T. P., Alves dos Santos, C., de Faria, D. A., Paiva, S. R. & McManus, C. Genomic selection signatures in Brazilian sheep breeds reared in a tropical environment. Livestock Sci. 258, 104865. https://doi.org/10.1016/j.livsci.2022.104865 (2022).Article
Google Scholar
Kusza, S. et al. Kompetitive Allele Specific PCR (KASPTM) genotyping of 48 polymorphisms at different caprine loci in French Alpine and Saanen goat breeds and their association with milk composition. PeerJ 6, e4416. https://doi.org/10.7717/peerj.4416 (2018).Article
CAS
Google Scholar
Zhang, Y. et al. Technical note: Development and application of KASP assays for rapid screening of 8 genetic defects in Holstein cattle. J. Dairy Sci. 103(1), 619–624. https://doi.org/10.3168/jds.2019-16345 (2020).Article
CAS
Google Scholar
Chaari, A. Molecular chaperones biochemistry and role in neurodegenerative diseases. Int. J. Biol. Macromol. 131, 396–411. https://doi.org/10.1016/j.ijbiomac.2019.02.148 (2019).Article
CAS
Google Scholar
Tripathy, K., Sodhi, M., Kataria, R. S., Chopra, M. & Mukesh, M. In silico analysis of HSP70 gene family in bovine genome. Biochem. Genet. 59(1), 134–158. https://doi.org/10.1007/s10528-020-09994-7 (2021).Article
CAS
Google Scholar
Rehman, S. et al. Genomic identification, evolution and sequence analysis of the heat-shock protein gene family in buffalo. Genes 11(11), 1388. https://doi.org/10.3390/genes11111388 (2020).Article
CAS
Google Scholar
Huo, C. et al. Chronic heat stress negatively affects the immune functions of both spleens and intestinal mucosal system in pigs through the inhibition of apoptosis. Microbial Pathog. 136, 103672. https://doi.org/10.1016/j.micpath.2019.103672 (2019).Article
CAS
Google Scholar
Morange, M. HSFs in development. In Molecular Chaperones in Health and Disease 153–169 (Springer, 2006). https://doi.org/10.1007/3-540-29717-0_7.Chapter
Google Scholar
Hoter, A., El-Sabban, M. & Naim, H. The HSP90 family: Structure, regulation, function, and implications in health and disease. Int. J. Mol. Sci. 19(9), 2560. https://doi.org/10.3390/ijms19092560 (2018).Article
CAS
Google Scholar
Vanselow, J., Vernunft, A., Koczan, D., Spitschak, M. & Kuhla, B. Exposure of lactating dairy cows to acute pre-ovulatory heat stress affects granulosa cell-specific gene expression profiles in dominant follicles. PLoS One 11(8), e0160600. https://doi.org/10.1371/journal.pone.0160600 (2016).Article
CAS
Google Scholar
Joy, A. et al. Resilience of small ruminants to climate change and increased environmental temperature: A review. Animals 10(5), 86. https://doi.org/10.3390/ani10050867 (2020).Article
Google Scholar
Saravanan, K. A. et al. Genomic scans for selection signatures revealed candidate genes for adaptation and production traits in a variety of cattle breeds. Genomics 113(3), 955–963. https://doi.org/10.1016/j.ygeno.2021.02.009 (2021).Article
CAS
Google Scholar
Singh, A. K., Upadhyay, R. C., Malakar, D., Kumar, S. & Singh, S. V. Effect of thermal stress on HSP70 expression in dermal fibroblast of zebu (Tharparkar) and crossbred (Karan-Fries) cattle. J. Therm. Biol 43, 46–53. https://doi.org/10.1016/j.jtherbio.2014.04.006 (2014).Article
CAS
Google Scholar
Verma, N., Gupta, I. D., Verma, A., Kumar, R. & Das, R. Novel SNPs in HSPB8 gene and their association with heat tolerance traits in Sahiwal indigenous cattle. Trop. Anim. Health Prod. 48(1), 175–180. https://doi.org/10.1007/s11250-015-0938-9 (2016).Article
Google Scholar
Al-Thuwaini, T. M., Al-Shuhaib, M. B. S. & Hussein, Z. M. A novel T177P missense variant in the HSPA8 gene associated with the low tolerance of Awassi sheep to heat stress. Trop. Anim. Health Prod. 52(5), 2405–2416. https://doi.org/10.1007/s11250-020-02267-w (2020).Article
Google Scholar
Onasanya, G. O. et al. Heterozygous single-nucleotide polymorphism genotypes at heat shock protein 70 gene potentially influence thermo-tolerance among four Zebu breeds of Nigeria. Front. Genet. https://doi.org/10.3389/fgene.2021.642213 (2021).Article
Google Scholar
Pascal, C. Researches regarding quality of sheep skins obtained from Karakul from Botosani sheep. Biotechnol. Anim. Husband. 27(3), 1123–1130. https://doi.org/10.2298/BAH1103123P (2011).Article
Google Scholar
Kevorkian, S. E. M., Zǎuleţ, M., Manea, M. A., Georgescu, S. E. & Costache, M. Analysis of the ORF region of the prion protein gene in the Botosani Karakul sheep breed from Romania. Turk. J. Vet. Anim. Sci. 35(2), 105–109. https://doi.org/10.3906/vet-0909-124 (2011).Article
CAS
Google Scholar
Kusza, S. et al. Mitochondrial DNA variability in Gyimesi Racka and Turcana sheep breeds. Acta Biochim. Pol. 62(2), 273–280. https://doi.org/10.18388/abp.2015_978 (2015).Article
CAS
Google Scholar
Gavojdian, D. et al. Effects of using indigenous heritage sheep breeds in organic and low-input production systems on production efficiency and animal welfare in Romania. Landbauforschung Volkenrode 66(4), 290–297. https://doi.org/10.3220/LBF1483607712000 (2016).Article
Google Scholar
Gavojdian, D. et al. Reproduction efficiency and health traits in Dorper, White Dorper, and Tsigai sheep breeds under temperate European conditions. Asian Australas. J. Anim. Sci. 28(4), 599–603. https://doi.org/10.5713/ajas.14.0659 (2015).Article
CAS
Google Scholar
Kusza, S. et al. The genetic variability of Hungarian Tsigai sheep. Archiv Tierzuch 53(3), 309–317 (2010).
Google Scholar
Kusza, S. et al. Study of genetic differences among Slovak Tsigai populations using microsatellite markers. Czeh J. Anim. Sci. 54(10), 468–474. https://doi.org/10.17221/1670-CJAS (2009).Article
CAS
Google Scholar
Marcos-Carcavilla, A. et al. Polymorphisms in the HSP90AA1 5′ flanking region are associated with scrapie incubation period in sheep. Cell Stress Chaperones 15(4), 343–349. https://doi.org/10.1007/s12192-009-0149-2 (2010).Article
CAS
Google Scholar
Salces-Ortiz, J. et al. Looking for adaptive footprints in the HSP90AA1 ovine gene. BMC Evol. Biol. 15(1), 7. https://doi.org/10.1186/s12862-015-0280-x (2015).Article
CAS
Google Scholar
Toscano, J. H. B. et al. Innate immune responses associated with resistance against Haemonchus contortus in Morada Nova Sheep. J. Immunol. Res. 2019, 1–10. https://doi.org/10.1155/2019/3562672 (2019).Article
CAS
Google Scholar
Estrada-Reyes, Z. M. et al. Signatures of selection for resistance to Haemonchus contortus in sheep and goats. BMC Genom. 20(1), 735. https://doi.org/10.1186/s12864-019-6150-y (2019).Article
CAS
Google Scholar
Caroprese, M., Bradford, B. J. & Rhoads, R. P. Editorial: Impact of climate change on immune responses in agricultural animals. Front. Vet. Sci. https://doi.org/10.3389/fvets.2021.732203 (2021).Article
Google Scholar
FAO/IAEA. Agriculture biotechnology laboratory—handbook of laboratory exercises. Seibersdorf: IAEA Laboratories, 18 (2004).Zsolnai, A. & Orbán, L. Accelerated separation of random complex DNA patterns in gels: Comparing the performance of discontinuous and continuous buffers. Electrophoresis 20(7), 1462–1468. https://doi.org/10.1002/(SICI)1522-2683(19990601)20:7%3c1462::AID-ELPS1462%3e3.0.CO;2-0 (1999).Article
CAS
Google Scholar
Cavalcanti, L. C. G. et al. Genetic characterization of coat color genes in Brazilian Crioula sheep from a conservation nucleus. Pesq. Agrop. Brasil. 52(8), 615–622. https://doi.org/10.1590/s0100-204×2017000800007 (2017).Article
Google Scholar
Li, Y. et al. Heat stress-responsive transcriptome analysis in the liver tissue of Hu sheep. Genes 10(5), 395. https://doi.org/10.3390/genes10050395 (2019).Article
CAS
Google Scholar
Younis, F. Expression pattern of heat shock protein genes in sheep. Mansoura Vet. Med. J. 21(1), 1–5. https://doi.org/10.35943/mvmj.2020.21.001 (2020).Article
Google Scholar
Yeh F. C., Boyle R., Yang R. C., Ye Z., Mao J. X. & Yeh D. POPGENE version 1.32. Computer program and documentation distributed by the author. http://www.ualberta.ca/∼fyeh/popgene.html (1999).Lê, S., Josse, J. & Husson, F. FactoMineR: A package for multivariate analysis. J. Stat. Softw. 25(1), 1–18. https://doi.org/10.18637/jss.v025.i01 (2008).Article
Google Scholar
Wickham H. ggplot2: Elegant Graphics for Data Analysis. Springer. https://ggplot2.tidyverse.org (2016) (ISBN 978-3-319-24277-4).R Core Team. R: A language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria. https://www.R-project.org/ (2020). More