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    J-WAFS announces 2023 seed grant recipients

    Today, the Abdul Latif Jameel Water and Food Systems Lab (J-WAFS) announced its ninth round of seed grants to support innovative research projects at MIT. The grants are designed to fund research efforts that tackle challenges related to water and food for human use, with the ultimate goal of creating meaningful impact as the world population continues to grow and the planet undergoes significant climate and environmental changes.Ten new projects led by 15 researchers from seven different departments will be supported this year. The projects address a range of challenges by employing advanced materials, technology innovations, and new approaches to resource management. The new projects aim to remove harmful chemicals from water sources, develop monitoring and other systems to help manage various aquaculture industries, optimize water purification materials, and more.“The seed grant program is J-WAFS’ flagship grant initiative,” says J-WAFS executive director Renee J. Robins. “The funding is intended to spur groundbreaking MIT research addressing complex issues that are challenging our water and food systems. The 10 projects selected this year show great promise, and we look forward to the progress and accomplishments these talented researchers will make,” she adds.The 2023 J-WAFS seed grant researchers and their projects are:Sara Beery, an assistant professor in the Department of Electrical Engineering and Computer Science (EECS), is building the first completely automated system to estimate the size of salmon populations in the Pacific Northwest (PNW).Salmon are a keystone species in the PNW, feeding human populations for the last 7,500 years at least. However, overfishing, habitat loss, and climate change threaten extinction of salmon populations across the region. Accurate salmon counts during their seasonal migration to their natal river to spawn are essential for fisheries’ regulation and management but are limited by human capacity. Fish population monitoring is a widespread challenge in the United States and worldwide. Beery and her team are working to build a system that will provide a detailed picture of the state of salmon populations in unprecedented, spatial, and temporal resolution by combining sonar sensors and computer vision and machine learning (CVML) techniques. The sonar will capture individual fish as they swim upstream and CVML will train accurate algorithms to interpret the sonar video for detecting, tracking, and counting fish automatically while adapting to changing river conditions and fish densities.Another aquaculture project is being led by Michael Triantafyllou, the Henry L. and Grace Doherty Professor in Ocean Science and Engineering in the Department of Mechanical Engineering, and Robert Vincent, the assistant director at MIT’s Sea Grant Program. They are working with Otto Cordero, an associate professor in the Department of Civil and Environmental Engineering, to control harmful bacteria blooms in aquaculture algae feed production.

    Aquaculture in the United States represents a $1.5 billion industry annually and helps support 1.7 million jobs, yet many American hatcheries are not able to keep up with demand. One barrier to aquaculture production is the high degree of variability in survival rates, most likely caused by a poorly controlled microbiome that leads to bacterial infections and sub-optimal feed efficiency. Triantafyllou, Vincent, and Cordero plan to monitor the microbiome composition of a shellfish hatchery in order to identify possible causing agents of mortality, as well as beneficial microbes. They hope to pair microbe data with detail phenotypic information about the animal population to generate rapid diagnostic tests and explore the potential for microbiome therapies to protect larvae and prevent future outbreaks. The researchers plan to transfer their findings and technology to the local and regional aquaculture community to ensure healthy aquaculture production that will support the expansion of the U.S. aquaculture industry.

    David Des Marais is the Cecil and Ida Green Career Development Professor in the Department of Civil and Environmental Engineering. His 2023 J-WAFS project seeks to understand plant growth responses to elevated carbon dioxide (CO2) in the atmosphere, in the hopes of identifying breeding strategies that maximize crop yield under future CO2 scenarios.Today’s crop plants experience higher atmospheric CO2 than 20 or 30 years ago. Crops such as wheat, oat, barley, and rice typically increase their growth rate and biomass when grown at experimentally elevated atmospheric CO2. This is known as the so-called “CO2 fertilization effect.” However, not all plant species respond to rising atmospheric CO2 with increased growth, and for the ones that do, increased growth doesn’t necessarily correspond to increased crop yield. Using specially built plant growth chambers that can control the concentration of CO2, Des Marais will explore how CO2 availability impacts the development of tillers (branches) in the grass species Brachypodium. He will study how gene expression controls tiller development, and whether this is affected by the growing environment. The tillering response refers to how many branches a plant produces, which sets a limit on how much grain it can yield. Therefore, optimizing the tillering response to elevated CO2 could greatly increase yield. Des Marais will also look at the complete genome sequence of Brachypodium, wheat, oat, and barley to help identify genes relevant for branch growth.Darcy McRose, an assistant professor in the Department of Civil and Environmental Engineering, is researching whether a combination of plant metabolites and soil bacteria can be used to make mineral-associated phosphorus more bioavailable.The nutrient phosphorus is essential for agricultural plant growth, but when added as a fertilizer, phosphorus sticks to the surface of soil minerals, decreasing bioavailability, limiting plant growth, and accumulating residual phosphorus. Heavily fertilized agricultural soils often harbor large reservoirs of this type of mineral-associated “legacy” phosphorus. Redox transformations are one chemical process that can liberate mineral-associated phosphorus. However, this needs to be carefully controlled, as overly mobile phosphorus can lead to runoff and pollution of natural waters. Ideally, phosphorus would be made bioavailable when plants need it and immobile when they don’t. Many plants make small metabolites called coumarins that might be able to solubilize mineral-adsorbed phosphorus and be activated and inactivated under different conditions. McRose will use laboratory experiments to determine whether a combination of plant metabolites and soil bacteria can be used as a highly efficient and tunable system for phosphorus solubilization. She also aims to develop an imaging platform to investigate exchanges of phosphorus between plants and soil microbes.Many of the 2023 seed grants will support innovative technologies to monitor, quantify, and remediate various kinds of pollutants found in water. Two of the new projects address the problem of per- and polyfluoroalkyl substances (PFAS), human-made chemicals that have recently emerged as a global health threat. Known as “forever chemicals,” PFAS are used in many manufacturing processes. These chemicals are known to cause significant health issues including cancer, and they have become pervasive in soil, dust, air, groundwater, and drinking water. Unfortunately, the physical and chemical properties of PFAS render them difficult to detect and remove.Aristide Gumyusenge, the Merton C. Assistant Professor of Materials Science and Engineering, is using metal-organic frameworks for low-cost sensing and capture of PFAS. Most metal-organic frameworks (MOFs) are synthesized as particles, which complicates their high accuracy sensing performance due to defects such as intergranular boundaries. Thin, film-based electronic devices could enable the use of MOFs for many applications, especially chemical sensing. Gumyusenge’s project aims to design test kits based on two-dimensional conductive MOF films for detecting PFAS in drinking water. In early demonstrations, Gumyusenge and his team showed that these MOF films can sense PFAS at low concentrations. They will continue to iterate using a computation-guided approach to tune sensitivity and selectivity of the kits with the goal of deploying them in real-world scenarios.Carlos Portela, the Brit (1961) and Alex (1949) d’Arbeloff Career Development Professor in the Department of Mechanical Engineering, and Ariel Furst, the Cook Career Development Professor in the Department of Chemical Engineering, are building novel architected materials to act as filters for the removal of PFAS from water. Portela and Furst will design and fabricate nanoscale materials that use activated carbon and porous polymers to create a physical adsorption system. They will engineer the materials to have tunable porosities and morphologies that can maximize interactions between contaminated water and functionalized surfaces, while providing a mechanically robust system.Rohit Karnik is a Tata Professor and interim co-department head of the Department of Mechanical Engineering. He is working on another technology, his based on microbead sensors, to rapidly measure and monitor trace contaminants in water.Water pollution from both biological and chemical contaminants contributes to an estimated 1.36 million deaths annually. Chemical contaminants include pesticides and herbicides, heavy metals like lead, and compounds used in manufacturing. These emerging contaminants can be found throughout the environment, including in water supplies. The Environmental Protection Agency (EPA) in the United States sets recommended water quality standards, but states are responsible for developing their own monitoring criteria and systems, which must be approved by the EPA every three years. However, the availability of data on regulated chemicals and on candidate pollutants is limited by current testing methods that are either insensitive or expensive and laboratory-based, requiring trained scientists and technicians. Karnik’s project proposes a simple, self-contained, portable system for monitoring trace and emerging pollutants in water, making it suitable for field studies. The concept is based on multiplexed microbead-based sensors that use thermal or gravitational actuation to generate a signal. His proposed sandwich assay, a testing format that is appealing for environmental sensing, will enable both single-use and continuous monitoring. The hope is that the bead-based assays will increase the ease and reach of detecting and quantifying trace contaminants in water for both personal and industrial scale applications.Alexander Radosevich, a professor in the Department of Chemistry, and Timothy Swager, the John D. MacArthur Professor of Chemistry, are teaming up to create rapid, cost-effective, and reliable techniques for on-site arsenic detection in water.Arsenic contamination of groundwater is a problem that affects as many as 500 million people worldwide. Arsenic poisoning can lead to a range of severe health problems from cancer to cardiovascular and neurological impacts. Both the EPA and the World Health Organization have established that 10 parts per billion is a practical threshold for arsenic in drinking water, but measuring arsenic in water at such low levels is challenging, especially in resource-limited environments where access to sensitive laboratory equipment may not be readily accessible. Radosevich and Swager plan to develop reaction-based chemical sensors that bind and extract electrons from aqueous arsenic. In this way, they will exploit the inherent reactivity of aqueous arsenic to selectively detect and quantify it. This work will establish the chemical basis for a new method of detecting trace arsenic in drinking water.Rajeev Ram is a professor in the Department of Electrical Engineering and Computer Science. His J-WAFS research will advance a robust technology for monitoring nitrogen-containing pollutants, which threaten over 15,000 bodies of water in the United States alone.Nitrogen in the form of nitrate, nitrite, ammonia, and urea can run off from agricultural fertilizer and lead to harmful algal blooms that jeopardize human health. Unfortunately, monitoring these contaminants in the environment is challenging, as sensors are difficult to maintain and expensive to deploy. Ram and his students will work to establish limits of detection for nitrate, nitrite, ammonia, and urea in environmental, industrial, and agricultural samples using swept-source Raman spectroscopy. Swept-source Raman spectroscopy is a method of detecting the presence of a chemical by using a tunable, single mode laser that illuminates a sample. This method does not require costly, high-power lasers or a spectrometer. Ram will then develop and demonstrate a portable system that is capable of achieving chemical specificity in complex, natural environments. Data generated by such a system should help regulate polluters and guide remediation.Kripa Varanasi, a professor in the Department of Mechanical Engineering, and Angela Belcher, the James Mason Crafts Professor and head of the Department of Biological Engineering, will join forces to develop an affordable water disinfection technology that selectively identifies, adsorbs, and kills “superbugs” in domestic and industrial wastewater.Recent research predicts that antibiotic-resistance bacteria (superbugs) will result in $100 trillion in health care expenses and 10 million deaths annually by 2050. The prevalence of superbugs in our water systems has increased due to corroded pipes, contamination, and climate change. Current drinking water disinfection technologies are designed to kill all types of bacteria before human consumption. However, for certain domestic and industrial applications there is a need to protect the good bacteria required for ecological processes that contribute to soil and plant health. Varanasi and Belcher will combine material, biological, process, and system engineering principles to design a sponge-based water disinfection technology that can identify and destroy harmful bacteria while leaving the good bacteria unharmed. By modifying the sponge surface with specialized nanomaterials, their approach will be able to kill superbugs faster and more efficiently. The sponge filters can be deployed under very low pressure, making them an affordable technology, especially in resource-constrained communities.In addition to the 10 seed grant projects, J-WAFS will also fund a research initiative led by Greg Sixt. Sixt is the research manager for climate and food systems at J-WAFS, and the director of the J-WAFS-led Food and Climate Systems Transformation (FACT) Alliance. His project focuses on the Lake Victoria Basin (LVB) of East Africa. The second-largest freshwater lake in the world, Lake Victoria straddles three countries (Uganda, Tanzania, and Kenya) and has a catchment area that encompasses two more (Rwanda and Burundi). Sixt will collaborate with Michael Hauser of the University of Natural Resources and Life Sciences, Vienna, and Paul Kariuki, of the Lake Victoria Basin Commission.The group will study how to adapt food systems to climate change in the Lake Victoria Basin. The basin is facing a range of climate threats that could significantly impact livelihoods and food systems in the expansive region. For example, extreme weather events like droughts and floods are negatively affecting agricultural production and freshwater resources. Across the LVB, current approaches to land and water management are unsustainable and threaten future food and water security. The Lake Victoria Basin Commission (LVBC), a specialized institution of the East African Community, wants to play a more vital role in coordinating transboundary land and water management to support transitions toward more resilient, sustainable, and equitable food systems. The primary goal of this research will be to support the LVBC’s transboundary land and water management efforts, specifically as they relate to sustainability and climate change adaptation in food systems. The research team will work with key stakeholders in Kenya, Uganda, and Tanzania to identify specific capacity needs to facilitate land and water management transitions. The two-year project will produce actionable recommendations to the LVBC. More

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    Solve at MIT 2023: Collaboration and climate efforts are at the forefront of social impact

    “The scale, complexity, the global nature of the problems we’re dealing with are so big that no single institution, industry, or country can deal with them alone,” MIT President Sally Kornbluth stated in her first remarks to the Solve community.

    Over 300 social impact leaders from around the world convened on MIT’s campus for Solve at MIT 2023 to celebrate the 2022 Solver class and to discuss some of the world’s greatest challenges and how we can tackle them with innovation, entrepreneurship, and technology.

    These challenges can be complicated and may even feel insurmountable, but Solve at MIT leaves us with the hope, tools, and connections needed to find solutions together.

    Hala Hanna, executive director of MIT Solve, shared what keeps her inspired and at the front line of social impact: “Optimism isn’t about looking away from the issues but looking right at them, believing we can create the solutions and putting in the work. So, anytime I need a dose of optimism, I look to the innovators we work with,” Hanna shared during the opening plenary, Unlocking our Collective Potential.

    Over the course of three days, more than 300 individuals from around the world convened to celebrate the 2022 Solver class, create partnerships that lead to progress, and address solutions to pressing world issues in real-time.

    Every technologist, philanthropist, investor, and innovator present at Solve at MIT left with their own takeaway, but three main themes seemed to underscore the overall discussions.

    Technology and innovation are as neutral as the makers

    Having bias is a natural part of what makes us human. However, being aware of our predispositions is necessary to transform our lived experiences into actionable solutions for others to benefit from. 

    We’ve largely learned that bias can be both unavoidable and applied almost instantly. Sangbae Kim, director of the Biomimetic Robotics Laboratory and professor of mechanical engineering at MIT, proved this through robotics demonstrations where attendees almost unanimously were more impressed with a back-flipping MIT robot compared to one walking in circles. As it turns out, it took one individual three days to program a robot to do a flip and over two weeks for a full team to program one to walk. “We judge through the knowledge and bias we have based on our lived experiences,” Kim pointed out.

    Bias and lived experiences don’t have to be bad things. The solutions we create based on our own lives are what matter. 

    2022 Solver Atif Javed, co-founder and executive director of Tarjimly, began translating for his grandmother as a child and learned about the struggles that come with being a refugee. This led him to develop a humanitarian language-translation application, which connects volunteer translators with immigrants, refugees, nongovernmental organizations (NGOs), and more, on demand. 

    Vanessa Castañeda Gill, 2022 Solver and co-founder and CEO of Social Cipher, transformed her personal experience with ADHD and autism to develop Ava, a video game empowering neuro-divergent youth and facilitating social-emotional learning.

    For Kelsey Wirth, co-founder and chair of Mothers Out Front, the experience of motherhood and the shared concerns for the well-being of children are what unite her with other moms. 

    Whitney Wolf Herd, founder and CEO of Bumble, shared that as a leader in technology and a person who witnessed toxic online spaces, she sees it as her responsibility to spearhead change. 

    During the plenary, “Bringing us Together or Tearing us Apart?” Wolf Herd asked, “What if we could use technology to be a force for positivity?” She shared her vision for equality and respect to be part of the next digital wave. She also called for technology leaders to join her to ensure “guardrails and ground rules” are in place to make sure this goal becomes a reality.

    Social innovation must be intersectional and intergenerational

    During Solve at MIT, industry leaders across sectors, cultures, ages, and expertise banded together to address pressing issues and to form relationships with innovators looking for support in real time.

    Adam Bly, founder and CEO of System Inc., discussed the interconnected nature of all things and why his organization is on a mission to show the links, “We’re seeing rising complexity in the systems that make up life on earth, and it impacts us individually and globally. The way we organize the information and data we need to make decisions about those systems [is highly] siloed and highly fragmented, and it impairs our ability to make decisions in the most systemic, holistic, rational way.”

    President and CEO of the National Resources Defense Council Manish Bapna shared his advocacy for cross-sector work: “Part of what I’ve seen really proliferate and expand in a good way over the past 10 to 15 years are collaborations involving startups in the private sector, governments, and NGOs. No single stakeholder or organization can solve the problem, but by coming together, they bring different perspectives and skills in ways that can create the innovation we need to see.”

    For a long time, STEM (science, technology, engineering, and math) were seen as the subjects that would resolve our complex issues, but as it turns out, art also holds a tremendous amount of power to transcend identity, borders, status, and concerns, to connect us all and aid us in global unity. Artists Beatie Wolfe, Norhan Bayomi, Aida Murad, and Nneka Jones showed us how to bring healing and awareness to topics like social and environmental injustice through their music, embroidery, and painting.

    The 2023 Solv[ED] Innovators, all age 24 or under, have solutions that are improving communication for individuals with hearing loss, transforming plastic waste into sustainable furniture, and protecting the Black birthing community, among other incredible feats.

    Kami Dar, co-founder and CEO of Uniti Networks, summarizes the value of interconnected problem-solving: “My favorite SDG [sustainable development goal] is SDG number 17— the power of partnership. Look for the adjacent problem-solvers and make sure we are not reinventing the wheel.”

    Relationships and the environment connect us all

    Solve is working to address global challenges on an ongoing basis connected to climate, economic prosperity, health, and learning. Many of these focus areas bleed into one another, but social justice and climate action served as a backdrop for many global issues addressed during Solve at MIT.

    “When we started addressing climate change, we saw it primarily as technical issues to bring down emissions … There’s inequality, there’s poverty, there are social tensions that are rising … We are not going to address climate change without addressing the social tensions that are embedded,” said Lewis Akenji, managing director of the Hot or Cool Institute. Akenji sees food, mobility, and housing as the most impactful areas to focus solutions on first.

    During the “Ensuring a Just Transition to Net Zero” plenary, Heather Clancy, vice president and editorial director at Greenbiz, asked panelists what lessons they have learned from their work. Janelle Knox Hayes, ​​professor of economic geography and planning at MIT, shared that listening to communities, especially front-line and Indigenous communities, is needed before deploying solutions to the energy crisis. “Climate work has this sense of urgency, like it rapidly has to be done … to do really engaged environmental justice work, we have to slow down and realize even before we begin, we need a long period of time to plan. But before we even do that, we have to rebuild relationships and trust and reciprocity … [This] will lead to better and longer-lasting solutions.”

    Hina Baloch, executive director and global head of climate change and sustainability strategy and communication at General Motors, asked Chéri Smith, founder of Indigenous Energy Initiative, to share her perspective on energy sovereignty as it relates to Indigenous communities. Smith shared, “Tribes can’t be sovereign if they’re relying on outside sources for their energy. We were founded to support the self-determination of tribes to revamp their energy systems and rebuild, construct, and maintain them themselves.”

    Smith shared an example of human and tribal-centered innovation in the making. Through the Biden administration’s national electronic vehicle (EV) initiative, Indigenous Energy Initiative and Native Sun Community Power Development will collaborate and create an inter-tribal EV charging network. “The last time we built out an electric grid, it deliberately skipped over tribal country. This time, we want to make sure that we not only have a seat at the table, but that we build out the tables and invite everyone to them,” said Smith.

    Solve at MIT led to meaningful discussions about climate change, intersectional and accessible innovation, and the power that human connection has to unite everyone. Entrepreneurship and social change are the paths forward. And although the challenges ahead of us can be daunting, with community, collaboration, and a healthy dose of bravery, global challenges will continue to be solved by agile impact entrepreneurs all around the world. 

    As Adrianne Haslet, a professional ballroom dancer and Boston Marathon bombing survivor, reminded attendees, “What will get you to the finish line is nothing compared to what got you to the start line.” More

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    Inaugural J-WAFS Grand Challenge aims to develop enhanced crop variants and move them from lab to land

    According to MIT’s charter, established in 1861, part of the Institute’s mission is to advance the “development and practical application of science in connection with arts, agriculture, manufactures, and commerce.” Today, the Abdul Latif Jameel Water and Food Systems Lab (J-WAFS) is one of the driving forces behind water and food-related research on campus, much of which relates to agriculture. In 2022, J-WAFS established the Water and Food Grand Challenge Grant to inspire MIT researchers to work toward a water-secure and food-secure future for our changing planet. Not unlike MIT’s Climate Grand Challenges, the J-WAFS Grand Challenge seeks to leverage multiple areas of expertise, programs, and Institute resources. The initial call for statements of interests returned 23 letters from MIT researchers spanning 18 departments, labs, and centers. J-WAFS hosted workshops for the proposers to present and discuss their initial ideas. These were winnowed down to a smaller set of invited concept papers, followed by the final proposal stage. 

    Today, J-WAFS is delighted to report that the inaugural J-WAFS Grand Challenge Grant has been awarded to a team of researchers led by Professor Matt Shoulders and research scientist Robert Wilson of the Department of Chemistry. A panel of expert, external reviewers highly endorsed their proposal, which tackles a longstanding problem in crop biology — how to make photosynthesis more efficient. The team will receive $1.5 million over three years to facilitate a multistage research project that combines cutting-edge innovations in synthetic and computational biology. If successful, this project could create major benefits for agriculture and food systems worldwide.

    “Food systems are a major source of global greenhouse gas emissions, and they are also increasingly vulnerable to the impacts of climate change. That’s why when we talk about climate change, we have to talk about food systems, and vice versa,” says Maria T. Zuber, MIT’s vice president for research. “J-WAFS is central to MIT’s efforts to address the interlocking challenges of climate, water, and food. This new grant program aims to catalyze innovative projects that will have real and meaningful impacts on water and food. I congratulate Professor Shoulders and the rest of the research team on being the inaugural recipients of this grant.”

    Shoulders will work with Bryan Bryson, associate professor of biological engineering, as well as Bin Zhang, associate professor of chemistry, and Mary Gehring, a professor in the Department of Biology and the Whitehead Institute for Biomedical Research. Robert Wilson from the Shoulders lab will be coordinating the research effort. The team at MIT will work with outside collaborators Spencer Whitney, a professor from the Australian National University, and Ahmed Badran, an assistant professor at the Scripps Research Institute. A milestone-based collaboration will also take place with Stephen Long, a professor from the University of Illinois at Urbana-Champaign. The group consists of experts in continuous directed evolution, machine learning, molecular dynamics simulations, translational plant biochemistry, and field trials.

    “This project seeks to fundamentally improve the RuBisCO enzyme that plants use to convert carbon dioxide into the energy-rich molecules that constitute our food,” says J-WAFS Director John H. Lienhard V. “This difficult problem is a true grand challenge, calling for extensive resources. With J-WAFS’ support, this long-sought goal may finally be achieved through MIT’s leading-edge research,” he adds.

    RuBisCO: No, it’s not a new breakfast cereal; it just might be the key to an agricultural revolution

    A growing global population, the effects of climate change, and social and political conflicts like the war in Ukraine are all threatening food supplies, particularly grain crops. Current projections estimate that crop production must increase by at least 50 percent over the next 30 years to meet food demands. One key barrier to increased crop yields is a photosynthetic enzyme called Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase (RuBisCO). During photosynthesis, crops use energy gathered from light to draw carbon dioxide (CO2) from the atmosphere and transform it into sugars and cellulose for growth, a process known as carbon fixation. RuBisCO is essential for capturing the CO2 from the air to initiate conversion of CO2 into energy-rich molecules like glucose. This reaction occurs during the second stage of photosynthesis, also known as the Calvin cycle. Without RuBisCO, the chemical reactions that account for virtually all carbon acquisition in life could not occur.

    Unfortunately, RuBisCO has biochemical shortcomings. Notably, the enzyme acts slowly. Many other enzymes can process a thousand molecules per second, but RuBisCO in chloroplasts fixes less than six carbon dioxide molecules per second, often limiting the rate of plant photosynthesis. Another problem is that oxygen (O2) molecules and carbon dioxide molecules are relatively similar in shape and chemical properties, and RuBisCO is unable to fully discriminate between the two. The inadvertent fixation of oxygen by RuBisCO leads to energy and carbon loss. What’s more, at higher temperatures RuBisCO reacts even more frequently with oxygen, which will contribute to decreased photosynthetic efficiency in many staple crops as our climate warms.

    The scientific consensus is that genetic engineering and synthetic biology approaches could revolutionize photosynthesis and offer protection against crop losses. To date, crop RuBisCO engineering has been impaired by technological obstacles that have limited any success in significantly enhancing crop production. Excitingly, genetic engineering and synthetic biology tools are now at a point where they can be applied and tested with the aim of creating crops with new or improved biological pathways for producing more food for the growing population.

    An epic plan for fighting food insecurity

    The 2023 J-WAFS Grand Challenge project will use state-of-the-art, transformative protein engineering techniques drawn from biomedicine to improve the biochemistry of photosynthesis, specifically focusing on RuBisCO. Shoulders and his team are planning to build what they call the Enhanced Photosynthesis in Crops (EPiC) platform. The project will evolve and design better crop RuBisCO in the laboratory, followed by validation of the improved enzymes in plants, ultimately resulting in the deployment of enhanced RuBisCO in field trials to evaluate the impact on crop yield. 

    Several recent developments make high-throughput engineering of crop RuBisCO possible. RuBisCO requires a complex chaperone network for proper assembly and function in plants. Chaperones are like helpers that guide proteins during their maturation process, shielding them from aggregation while coordinating their correct assembly. Wilson and his collaborators previously unlocked the ability to recombinantly produce plant RuBisCO outside of plant chloroplasts by reconstructing this chaperone network in Escherichia coli (E. coli). Whitney has now established that the RuBisCO enzymes from a range of agriculturally relevant crops, including potato, carrot, strawberry, and tobacco, can also be expressed using this technology. Whitney and Wilson have further developed a range of RuBisCO-dependent E. coli screens that can identify improved RuBisCO from complex gene libraries. Moreover, Shoulders and his lab have developed sophisticated in vivo mutagenesis technologies that enable efficient continuous directed evolution campaigns. Continuous directed evolution refers to a protein engineering process that can accelerate the steps of natural evolution simultaneously in an uninterrupted cycle in the lab, allowing for rapid testing of protein sequences. While Shoulders and Badran both have prior experience with cutting-edge directed evolution platforms, this will be the first time directed evolution is applied to RuBisCO from plants.

    Artificial intelligence is changing the way enzyme engineering is undertaken by researchers. Principal investigators Zhang and Bryson will leverage modern computational methods to simulate the dynamics of RuBisCO structure and explore its evolutionary landscape. Specifically, Zhang will use molecular dynamics simulations to simulate and monitor the conformational dynamics of the atoms in a protein and its programmed environment over time. This approach will help the team evaluate the effect of mutations and new chemical functionalities on the properties of RuBisCO. Bryson will employ artificial intelligence and machine learning to search the RuBisCO activity landscape for optimal sequences. The computational and biological arms of the EPiC platform will work together to both validate and inform each other’s approaches to accelerate the overall engineering effort.

    Shoulders and the group will deploy their designed enzymes in tobacco plants to evaluate their effects on growth and yield relative to natural RuBisCO. Gehring, a plant biologist, will assist with screening improved RuBisCO variants using the tobacco variety Nicotiana benthamianaI, where transient expression can be deployed. Transient expression is a speedy approach to test whether novel engineered RuBisCO variants can be correctly synthesized in leaf chloroplasts. Variants that pass this quality-control checkpoint at MIT will be passed to the Whitney Lab at the Australian National University for stable transformation into Nicotiana tabacum (tobacco), enabling robust measurements of photosynthetic improvement. In a final step, Professor Long at the University of Illinois at Urbana-Champaign will perform field trials of the most promising variants.

    Even small improvements could have a big impact

    A common criticism of efforts to improve RuBisCO is that natural evolution has not already identified a better enzyme, possibly implying that none will be found. Traditional views have speculated a catalytic trade-off between RuBisCO’s specificity factor for CO2 / O2 versus its CO2 fixation efficiency, leading to the belief that specificity factor improvements might be offset by even slower carbon fixation or vice versa. This trade-off has been suggested to explain why natural evolution has been slow to achieve a better RuBisCO. But Shoulders and the team are convinced that the EPiC platform can unlock significant overall improvements to plant RuBisCO. This view is supported by the fact that Wilson and Whitney have previously used directed evolution to improve CO2 fixation efficiency by 50 percent in RuBisCO from cyanobacteria (the ancient progenitors of plant chloroplasts) while simultaneously increasing the specificity factor. 

    The EPiC researchers anticipate that their initial variants could yield 20 percent increases in RuBisCO’s specificity factor without impairing other aspects of catalysis. More sophisticated variants could lift RuBisCO out of its evolutionary trap and display attributes not currently observed in nature. “If we achieve anywhere close to such an improvement and it translates to crops, the results could help transform agriculture,” Shoulders says. “If our accomplishments are more modest, it will still recruit massive new investments to this essential field.”

    Successful engineering of RuBisCO would be a scientific feat of its own and ignite renewed enthusiasm for improving plant CO2 fixation. Combined with other advances in photosynthetic engineering, such as improved light usage, a new green revolution in agriculture could be achieved. Long-term impacts of the technology’s success will be measured in improvements to crop yield and grain availability, as well as resilience against yield losses under higher field temperatures. Moreover, improved land productivity together with policy initiatives would assist in reducing the environmental footprint of agriculture. With more “crop per drop,” reductions in water consumption from agriculture would be a major boost to sustainable farming practices.

    “Our collaborative team of biochemists and synthetic biologists, computational biologists, and chemists is deeply integrated with plant biologists and field trial experts, yielding a robust feedback loop for enzyme engineering,” Shoulders adds. “Together, this team will be able to make a concerted effort using the most modern, state-of-the-art techniques to engineer crop RuBisCO with an eye to helping make meaningful gains in securing a stable crop supply, hopefully with accompanying improvements in both food and water security.” More

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    US and UAE governments highlight early warning system for climate resilience

    The following is a joint announcement from MIT and Community Jameel.

    An international project to build community resilience to the effects of climate change, launched by Community Jameel and a research team at MIT, has been recognized as an innovation sprint at the 2023 summit of the United States’ and United Arab Emirates’ Agriculture Innovation Mission for Climate (AIM4C).

    The Jameel Observatory Climate Resilience Early Warning System Network (Jameel Observatory-CREWSnet), one of MIT’s five Climate Grand Challenges flagship projects, aims to empower communities worldwide, specifically within the agriculture sector, to adapt to climate shocks by launching cross-sector collaborations and by combining state-of-the-art climate and socioeconomic forecasting techniques with technological solutions to support communities’ resilience.

    AIM4C is a joint initiative of the U.S. and U.A.E. that seeks to enhance climate action by accelerating agriculture and food systems innovation and investment. Innovation sprints are selected by AIM4C to accelerate their impact following a competitive process that considers scientific excellence and financial support.

    “As we launch Jameel Observatory-CREWSnet, the AIM4C summit offers a great opportunity to share our plans and initial work with all those who are interested in enhancing the capacity of agricultural communities in vulnerable countries to deal with challenges of climate change,” says Elfatih Eltahir, HM King Bhumibol Professor of Hydrology and Climate at MIT and project leader of the Jameel Observatory-CREWSnet.

    Jameel Observatory-CREWSnet seeks to bridge the gap between the knowledge about climate change created at research institutions such as MIT and the local farming communities that are adapting to the impacts of climate change. By effectively informing and engaging local communities, the project seeks to enable farmers to sustainably increase their agricultural productivity and income.     

    The Jameel Observatory-CREWSnet will initially pilot in Bangladesh and Sudan, working with local partners BRAC, a leading international nonprofit headquartered in Bangladesh, and the Agricultural Research Corporation-Sudan, the principal agricultural research arm of the Sudanese government, and with MIT’s Abdul Latif Jameel Poverty Action Lab (J-PAL), the global research center working to reduce poverty by ensuring that policy is informed by scientific evidence. Beginning in southwestern Bangladesh, the Jameel Observatory-CREWSnet will integrate next-generation climate forecasting, predictive analytics, new technologies, and financial instruments. In East Africa, with a focus on Sudan, the initiative will emphasize adopting modern technology to use a better variety of heat-resistant seeds, increasing the use of targeted fertilizers, strengthening soils through soil fertility mapping combined with data modeling, and emphasizing vertical expansion of agriculture over traditional horizontal expansion. The work in Sudan is extensible to other regions in Africa. Jameel Observatory-CREWSnet’s activities and timeline will be reevaluated as the team monitors the ongoing situation in Sudan.

    Using local climate insights, communities will be empowered to adapt proactively to climate change by optimally planning their agricultural activities, targeting emergent economic opportunities, and proactively managing risks from climate change.

    George Richards, director of Community Jameel, says: “Community Jameel is proud to be collaborating with MIT, BRAC, and the Agricultural Research Corporation-Sudan to empower agricultural communities to adapt to the ever-growing challenges arising from climate change — challenges which, as we are seeing acutely in Sudan, are compounded by other crises. We welcome the support of the U.S. and U.A.E. governments in selecting the Jameel Observatory-CREWSnet as an AIM4C innovation sprint.”

    Md Liakath Ali, director of climate change, urban development, and disaster risk management at BRAC, says: “Over our five decades working alongside climate-vulnerable communities in Bangladesh, BRAC has seen firsthand how locally led climate adaptation helps protect lives and livelihoods. BRAC is proud to work with Community Jameel and MIT to empower vulnerable communities to proactively adapt to the impacts of climate change.”

    The Jameel Observatory-CREWSnet was launched at COP27 in Sharm El Sheikh as part of the Jameel Observatory, an international collaboration launched in 2021 that focuses on convening researchers and practitioners who use data and technology to help communities adapt to the impacts of climate change and short-term climate shocks.

    The Jameel Observatory focuses on using data and evidence to prepare for and act on environmental shocks as well as those impacts of climate change and variability which threaten human and environmental well-being. With a special focus on low- and middle-income countries, the Jameel Observatory works at the interface of climate, natural disasters, agricultural and food systems, and health. It emphasizes the need to incorporate local as well as scientific knowledge to prepare and act in anticipation of environmental shocks.

    Launched in 2020, MIT’s Climate Grand Challenges initiative is designed to mobilize the Institute’s research community around tackling the most difficult unsolved climate problems in emissions reduction, climate adaptation and resilience, risk forecasting, carbon removal, and understanding the human impacts of climate change. MIT selected 27 teams as finalists from a field of nearly 100 initial proposals. In 2022, five teams with the most promising concepts were announced as multi-year flagship projects. More

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    Moving perovskite advancements from the lab to the manufacturing floor

    The following was issued as a joint announcement from MIT.nano and the MIT Research Laboratory for Electronics; CubicPV; Verde Technologies; Princeton University; and the University of California at San Diego.

    Tandem solar cells are made of stacked materials — such as silicon paired with perovskites — that together absorb more of the solar spectrum than single materials, resulting in a dramatic increase in efficiency. Their potential to generate significantly more power than conventional cells could make a meaningful difference in the race to combat climate change and the transition to a clean-energy future.

    However, current methods to create stable and efficient perovskite layers require time-consuming, painstaking rounds of design iteration and testing, inhibiting their development for commercial use. Today, the U.S. Department of Energy Solar Energy Technologies Office (SETO) announced that MIT has been selected to receive an $11.25 million cost-shared award to establish a new research center to address this challenge by using a co-optimization framework guided by machine learning and automation.

    A collaborative effort with lead industry participant CubicPV, solar startup Verde Technologies, and academic partners Princeton University and the University of California San Diego (UC San Diego), the center will bring together teams of researchers to support the creation of perovskite-silicon tandem solar modules that are co-designed for both stability and performance, with goals to significantly accelerate R&D and the transfer of these achievements into commercial environments.

    “Urgent challenges demand rapid action. This center will accelerate the development of tandem solar modules by bringing academia and industry into closer partnership,” says MIT professor of mechanical engineering Tonio Buonassisi, who will direct the center. “We’re grateful to the Department of Energy for supporting this powerful new model and excited to get to work.”

    Adam Lorenz, CTO of solar energy technology company CubicPV, stresses the importance of thinking about scale, alongside quality and efficiency, to accelerate the perovskite effort into the commercial environment. “Instead of chasing record efficiencies with tiny pixel-sized devices and later attempting to stabilize them, we will simultaneously target stability, reproducibility, and efficiency,” he says. “It’s a module-centric approach that creates a direct channel for R&D advancements into industry.”

    The center will be named Accelerated Co-Design of Durable, Reproducible, and Efficient Perovskite Tandems, or ADDEPT. The grant will be administered through the MIT Research Laboratory for Electronics (RLE).

    David Fenning, associate professor of nanoengineering at UC San Diego, has worked with Buonassisi on the idea of merging materials, automation, and computation, specifically in this field of artificial intelligence and solar, since 2014. Now, a central thrust of the ADDEPT project will be to deploy machine learning and robotic screening to optimize processing of perovskite-based solar materials for efficiency and durability.

    “We have already seen early indications of successful technology transfer between our UC San Diego robot PASCAL and industry,” says Fenning. “With this new center, we will bring research labs and the emerging perovskite industry together to improve reproducibility and reduce time to market.”

    “Our generation has an obligation to work collaboratively in the fight against climate change,” says Skylar Bagdon, CEO of Verde Technologies, which received the American-Made Perovskite Startup Prize. “Throughout the course of this center, Verde will do everything in our power to help this brilliant team transition lab-scale breakthroughs into the world where they can have an impact.”

    Several of the academic partners echoed the importance of the joint effort between academia and industry. Barry Rand, professor of electrical and computer engineering at the Andlinger Center for Energy and the Environment at Princeton University, pointed to the intersection of scientific knowledge and market awareness. “Understanding how chemistry affects films and interfaces will empower us to co-design for stability and performance,” he says. “The center will accelerate this use-inspired science, with close guidance from our end customers, the industry partners.”

    A critical resource for the center will be MIT.nano, a 200,000-square-foot research facility set in the heart of the campus. MIT.nano Director Vladimir Bulović, the Fariborz Maseeh (1990) Professor of Emerging Technology, says he envisions MIT.nano as a hub for industry and academic partners, facilitating technology development and transfer through shared lab space, open-access equipment, and streamlined intellectual property frameworks.

    “MIT has a history of groundbreaking innovation using perovskite materials for solar applications,” says Bulović. “We’re thrilled to help build on that history by anchoring ADDEPT at MIT.nano and working to help the nation advance the future of these promising materials.”

    MIT was selected as a part of the SETO Fiscal Year 2022 Photovoltaics (PV) funding program, an effort to reduce costs and supply chain vulnerabilities, further develop durable and recyclable solar technologies, and advance perovskite PV technologies toward commercialization. ADDEPT is one project that will tackle perovskite durability, which will extend module life. The overarching goal of these projects is to lower the levelized cost of electricity generated by PV.

    Research groups involved with the ADDEPT project at MIT include Buonassisi’s Accelerated Materials Laboratory for Sustainability (AMLS), Bulović’s Organic and Nanostructured Electronics (ONE) Lab, and the Bawendi Group led by Lester Wolfe Professor in Chemistry Moungi Bawendi. Also working on the project is Jeremiah Mwaura, research scientist in the ONE Lab. More

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    Exploring the nanoworld of biogenic gems

    A new research collaboration with The Bahrain Institute for Pearls and Gemstones (DANAT) will seek to develop advanced characterization tools for the analysis of the properties of pearls and to explore technologies to assign unique identifiers to individual pearls.

    The three-year project will be led by Admir Mašić, associate professor of civil and environmental engineering, in collaboration with Vladimir Bulović, the Fariborz Maseeh Chair in Emerging Technology and professor of electrical engineering and computer science.

    “Pearls are extremely complex and fascinating hierarchically ordered biological materials that are formed by a wide range of different species,” says Mašić. “Working with DANAT provides us a unique opportunity to apply our lab’s multi-scale materials characterization tools to identify potentially species-specific pearl fingerprints, while simultaneously addressing scientific research questions regarding the underlying biomineralization processes that could inform advances in sustainable building materials.”

    DANAT is a gemological laboratory specializing in the testing and study of natural pearls as a reflection of Bahrain’s pearling history and desire to protect and advance Bahrain’s pearling heritage. DANAT’s gemologists support clients and students through pearl, gemstone, and diamond identification services, as well as educational courses.

    Like many other precious gemstones, pearls have been human-made through scientific experimentation, says Noora Jamsheer, chief executive officer at DANAT. Over a century ago, cultured pearls entered markets as a competitive product to natural pearls, similar in appearance but different in value.

    “Gemological labs have been innovating scientific testing methods to differentiate between natural pearls and all other pearls that exist because of direct or indirect human intervention. Today the world knows natural pearls and cultured pearls. However, there are also pearls that fall in between these two categories,” says Jamsheer. “DANAT has the responsibility, as the leading gemological laboratory for pearl testing, to take the initiative necessary to ensure that testing methods keep pace with advances in the science of pearl cultivation.”

    Titled “Exploring the Nanoworld of Biogenic Gems,” the project will aim to improve the process of testing and identifying pearls by identifying morphological, micro-structural, optical, and chemical features sufficient to distinguish a pearl’s area of origin, method of growth, or both. MIT.nano, MIT’s open-access center for nanoscience and nanoengineering will be the organizational home for the project, where Mašić and his team will utilize the facility’s state-of-the-art characterization tools.

    In addition to discovering new methodologies for establishing a pearl’s origin, the project aims to utilize machine learning to automate pearl classification. Furthermore, researchers will investigate techniques to create a unique identifier associated with an individual pearl.

    The initial sponsored research project is expected to last three years, with potential for continued collaboration based on key findings or building upon the project’s success to open new avenues for research into the structure, properties, and growth of pearls. More

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    MIT scientists contribute to National Ignition Facility fusion milestone

    On Monday, Dec. 5, at around 1 a.m., a tiny sphere of deuterium-tritium fuel surrounded by a cylindrical can of gold called a hohlraum was targeted by 192 lasers at the National Ignition Facility (NIF) at Lawrence Livermore National Laboratory (LLNL) in California. Over the course of billionths of a second, the lasers fired, generating X-rays inside the gold can, and imploding the sphere of fuel.

    On that morning, for the first time ever, the lasers delivered 2.1 megajoules of energy and yielded 3.15 megajoules in return, achieving a historic fusion energy gain well above 1 — a result verified by diagnostic tools developed by the MIT Plasma Science and Fusion Center (PSFC). The use of these tools and their importance was referenced by Arthur Pak, a LLNL staff scientist who spoke at a U.S. Department of Energy press event on Dec. 13 announcing the NIF’s success.

    Johan Frenje, head of the PSFC High-Energy-Density Physics division, notes that this milestone “will have profound implications for laboratory fusion research in general.”

    Since the late 1950s, researchers worldwide have pursued fusion ignition and energy gain in a laboratory, considering it one of the grand challenges of the 21st century. Ignition can only be reached when the internal fusion heating power is high enough to overcome the physical processes that cool the fusion plasma, creating a positive thermodynamic feedback loop that very rapidly increases the plasma temperature. In the case of inertial confinement fusion, the method used at the NIF, ignition can initiate a “fuel burn propagation” into the surrounding dense and cold fuel, and when done correctly, enable fusion-energy gain.

    Frenje and his PSFC division initially designed dozens of diagnostic systems that were implemented at the NIF, including the vitally important magnetic recoil neutron spectrometer (MRS), which measures the neutron energy spectrum, the data from which fusion yield, plasma ion temperature, and spherical fuel pellet compression (“fuel areal density”) can be determined. Overseen by PSFC Research Scientist Maria Gatu Johnson since 2013, the MRS is one of two systems at the NIF relied upon to measure the absolute neutron yield from the Dec. 5 experiment because of its unique ability to accurately interpret an implosion’s neutron signals.

    “Before the announcement of this historic achievement could be made, the LLNL team wanted to wait until Maria had analyzed the MRS data to an adequate level for a fusion yield to be determined,” says Frenje.

    Response around MIT to NIF’s announcement has been enthusiastic and hopeful. “This is the kind of breakthrough that ignites the imagination,” says Vice President for Research Maria Zuber, “reminding us of the wonder of discovery and the possibilities of human ingenuity. Although we have a long, hard path ahead of us before fusion can deliver clean energy to the electrical grid, we should find much reason for optimism in today’s announcement. Innovation in science and technology holds great power and promise to address some of the world’s biggest challenges, including climate change.”

    Frenje also credits the rest of the team at the PSFC’s High-Energy-Density Physics division, the Laboratory for Laser Energetics at the University of Rochester, LLNL, and other collaborators for their support and involvement in this research, as well as the National Nuclear Security Administration of the Department of Energy, which has funded much of their work since the early 1990s. He is also proud of the number of MIT PhDs that have been generated by the High-Energy-Density Physics Division and subsequently hired by LLNL, including the experimental lead for this experiment, Alex Zylstra PhD ’15.

    “This is really a team effort,” says Frenje. “Without the scientific dialogue and the extensive know-how at the HEDP Division, the critical contributions made by the MRS system would not have happened.” More

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    Decarbonization amid global crises

    A global pandemic. Russia’s invasion of Ukraine. Inflation. The first-ever serious challenge to the peaceful transfer of power in the United States.

    Forced to face a seemingly unending series of once-in-a-generation crises, how can the world continue to focus attention on goals around carbon emissions and climate change? That was the question posed by Philip R. Sharp, the former president of Resources for the Future and a former 10-term member of the U.S. House of Representatives from Indiana, during his MIT Energy Initiative Fall Colloquium address, entitled “The prospects for decarbonization in America: Will global and domestic crises disrupt our plans?”

    Perhaps surprisingly, Sharp sounded an optimistic note in his answer. Despite deep political divisions in the United States, he noted, Congress has passed five major pieces of legislation — under both presidents Donald Trump and Joseph Biden — aimed at accelerating decarbonization efforts. Rather than hampering movement to combat climate change, Sharp said, domestic and global crises have seemed to galvanize support, create new incentives for action, and even unify political rivals around the cause.

    “Almost everybody is dealing with, to some degree, the absolutely profound, churning events that we are amidst now. Most of them are unexpected, and therefore [we’re] not prepared for [them], and they have had a profound shaking of our thinking,” Sharp said. “The conventional wisdom has not held up in almost all of these areas, and therefore it makes it much more difficult for us to think we know how to predict an uncertain future, and [it causes us to] question our own ability as a nation — or anywhere — to actually take on these challenges. And obviously, climate change is one of the most important.”

    However, Sharp continued, these challenges have, in some instances, spurred action. The war in Ukraine, he noted, has upset European energy markets, but it has also highlighted the importance of countries achieving a more energy-independent posture through renewables. “In America,” he added, “we’ve actually seen absolutely stunning … behavior by the United States Congress, of all places.”

    “What we’ve witnessed is, [Congress] put out incredible … sums of money under the previous administration, and then under this administration, to deal with the Covid crisis,” Sharp added later in his talk. “And then the United States government came together — red and blue — to support the Ukrainians against Russia. It saddens me to say, it seems to take a Russian invasion or the Chinese probing us economically to get us moving. But we are moving, and these things are happening.”

    Congressional action

    Sharp cautioned against getting “caught up” in the familiar viewpoint that Congress, in its current incarnation, is fundamentally incapable of passing meaningful legislation. He pointed, in particular, to the passage of five laws over the previous two years:

    The 2020 Energy Act, which has been characterized as a “down payment on fighting climate change.”
    The Infrastructure Investment and Jobs Act (sometimes called the “bipartisan infrastructure bill”), which calls for investments in passenger rail, electric vehicle infrastructure, electric school buses, and other clean-energy measures;
    The CHIPS and Science Act, a $280 billion effort to revitalize the American semiconductor industry, which some analysts say could direct roughly one-quarter of its funding toward accelerating zero-carbon industries and conducting climate research;
    The Inflation Reduction Act (called by some “the largest climate legislation in U.S. history”), which includes tax credits, incentives, and other provisions to help private companies tackle climate change, increase investments in renewable energy, and enhance energy efficiency; and
    The Kigali Amendment to the Montreal Protocol, ratified by the Senate to little fanfare in September, under which the United States agreed to reduce the consumption and production of hydrofluorocarbons (HFCs).
    “It is a big deal,” Sharp said of the dramatic increase in federal climate action. “It is very significant actions that are being taken — more than what we would expect, or I would expect, out of the Congress at any one time.”

    Along with the many billions of dollars of climate-related investments included in the legislation, Sharp said, these new laws will have a number of positive “spillover” effects.

    “This enables state governments, in their policies, to be more aggressive,” Sharp said. “Why? Because it makes it cheaper for some of the investments that they will try to force within their state.” Another “pretty obvious” spillover effect, Sharp said, is that the new laws will enhance U.S. credibility in international negotiations. Finally, he said, these public investments will make the U.S. economy more competitive in international markets for clean-energy technology — particularly as the United States seeks to compete against China in the space.

    “[Competition with China] has become a motivator in American politics, like it or not,” Sharp said. “There is no question that it is causing and bringing together [politicians] across blue [states] and red [states].”

    Holding onto progress

    Even in an uncertain political climate in which Democrats and Republicans seem unable to agree on basic facts, recent funding commitments are likely to survive, no matter which party controls Congress and the presidency, Sharp said. That’s because most of the legislation relies on broadly popular “carrots” that reward investments in decarbonization, rather than less popular “sticks” that create new restrictions or punishments for companies that fail to decarbonize.

    “Politically, the impact of this is very significant,” Sharp said. “It is so much easier in politics to give away tax [credits] than it is to penalize or put requirements onto people. The fact is that these tax credits are more likely to be politically sustained than other forms of government intervention. That, at least, has been the history.”

    Sharp stressed the importance of what he called “civil society” — institutions such as universities, nonprofits, churches, and other organizations that are apart from government and business — in promoting decarbonization efforts. “[Those groups] can act highly independently, and therefore, they can drive for things that others are not willing to do. Now this does not always work to good purposes. Partly, this diversity and this decentralization in civil society … led to deniers and others being able to stop some climate action. But now my view is, this is starting to all move in the right direction, in a very dynamic and a very important way. What we have seen over the last few years is a big uptick in philanthropy related to climate.”

    Looking ahead

    Sharp’s optimism even extended to the role of social media. He suggested that the “Wild West” era of social platforms may be ending, pointing to the celebrities who have recently lost valuable business partnerships for spreading hate speech and disinformation. “We’re now a lot more alert to the dangers,” he said.

    Some in the audience questioned Sharp about specific paths toward decarbonization, but Sharp said that progress will require a number of disparate approaches — some of which will inevitably have a greater impact than others. “The current policy, and the policy embedded in this [new] legislation … is all about doing both,” he said. “It’s all about advancing [current] technologies into the marketplace, and at the same time driving for breakthroughs.”

    Above all, Sharp stressed the need for continued collective action around climate change. “The fact is, we’re all contributors to some degree,” he said. “But we also all can do something. In my view, this is clearly not a time for hand-wringing. This is a time for action. People have to roll up their sleeves, and go to work, and not roll them down anytime soon.” More