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    Is there enough land on Earth to fight climate change and feed the world?

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    Capping global warming at 1.5 degrees Celsius is a tall order. Achieving that goal will not only require a massive reduction in greenhouse gas emissions from human activities, but also a substantial reallocation of land to support that effort and sustain the biosphere, including humans. More land will be needed to accommodate a growing demand for bioenergy and nature-based carbon sequestration while ensuring sufficient acreage for food production and ecological sustainability.The expanding role of land in a 1.5 C world will be twofold — to remove carbon dioxide from the atmosphere and to produce clean energy. Land-based carbon dioxide removal strategies include bioenergy with carbon capture and storage; direct air capture; and afforestation/reforestation and other nature-based solutions. Land-based clean energy production includes wind and solar farms and sustainable bioenergy cropland. Any decision to allocate more land for climate mitigation must also address competing needs for long-term food security and ecosystem health.Land-based climate mitigation choices vary in terms of costs — amount of land required, implications for food security, impact on biodiversity and other ecosystem services — and benefits — potential for sequestering greenhouse gases and producing clean energy.Now a study in the journal Frontiers in Environmental Science provides the most comprehensive analysis to date of competing land-use and technology options to limit global warming to 1.5 C. Led by researchers at the MIT Center for Sustainability Science and Strategy (CS3), the study applies the MIT Integrated Global System Modeling (IGSM) framework to evaluate costs and benefits of different land-based climate mitigation options in Sky2050, a 1.5 C climate-stabilization scenario developed by Shell.Under this scenario, demand for bioenergy and natural carbon sinks increase along with the need for sustainable farming and food production. To determine if there’s enough land to meet all these growing demands, the research team uses the global hectare (gha) — an area of 10,000 square meters, or 2.471 acres — as the standard unit of measurement, and current estimates of the Earth’s total habitable land area (about 10 gha) and land area used for food production and bioenergy (5 gha).The team finds that with transformative changes in policy, land management practices, and consumption patterns, global land is sufficient to provide a sustainable supply of food and ecosystem services throughout this century while also reducing greenhouse gas emissions in alignment with the 1.5 C goal. These transformative changes include policies to protect natural ecosystems; stop deforestation and accelerate reforestation and afforestation; promote advances in sustainable agriculture technology and practice; reduce agricultural and food waste; and incentivize consumers to purchase sustainably produced goods.If such changes are implemented, 2.5–3.5 gha of land would be used for NBS practices to sequester 3–6 gigatonnes (Gt) of CO2 per year, and 0.4–0.6 gha of land would be allocated for energy production — 0.2–0.3 gha for bioenergy and 0.2–0.35 gha for wind and solar power generation.“Our scenario shows that there is enough land to support a 1.5 degree C future as long as effective policies at national and global levels are in place,” says CS3 Principal Research Scientist Angelo Gurgel, the study’s lead author. “These policies must not only promote efficient use of land for food, energy, and nature, but also be supported by long-term commitments from government and industry decision-makers.” More

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      Linzixuan (Rhoda) Zhang wins 2024 Collegiate Inventors Competition

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      Linzixuan (Rhoda) Zhang, a doctoral candidate in the MIT Department of Chemical Engineering, recently won the 2024 Collegiate Inventors Competition, medaling in both the Graduate and People’s Choice categories for developing materials to stabilize nutrients in food with the goal of improving global health.  The annual competition, organized by the National Inventors Hall of Fame and United States Patent and Trademark Office (USPTO), celebrates college and university student inventors. The finalists present their inventions to a panel of final-round judges composed of National Inventors Hall of Fame inductees and USPTO officials. No stranger to having her work in the limelight, Zhang is a three-time winner of the Koch Institute Image Awards in 2022, 2023, and 2024, as well as a 2022 fellow at the MIT Abdul Latif Jameel Water and Food Systems Lab.  “Rhoda is an exceptionally dedicated and creative student. Her well-deserved award recognizes the potential of her research on nutrient stabilization, which could have a significant impact on society,” says Ana Jaklenec, one of Zhang’s advisors and a principal investigator at MIT’s Koch Institute for Integrative Cancer Research. Zhang is also advised by David H. Koch (1962) Institute Professor Robert Langer. Frameworks for global healthIn a world where nearly 2 billion people suffer from micronutrient deficiencies, particularly iron, the urgency for effective solutions has never been greater. Iron deficiency is especially harmful for vulnerable populations such as children and pregnant women, since it can lead to weakened immune systems and developmental delays. The World Health Organization has highlighted food fortification as a cost-effective strategy, yet many current methods fall short. Iron and other nutrients can break down during processing or cooking, and synthetic additives often come with high costs and environmental drawbacks. Zhang, along with her teammate, Xin Yang, a postdoc associate at Koch Institute, set out to innovate new technologies for nutrient fortification that are effective, accessible, and sustainable, leading to the invention nutritional metal-organic frameworks (NuMOFs) and the subsequent launch of MOFe Coffee, the world’s first iron-fortified coffee. NuMOFs not only protect essential nutrients such as iron while in food for long periods of time, but also make them more easily absorbed and used once consumed.The inspiration for the coffee came from the success of iodized salt, which significantly reduced iodine deficiency worldwide. Because coffee and tea are associated with low iron absorption, iron fortification would directly address the challenge.However, replicating the success of iodized salt for iron fortification has been extremely challenging due to the micronutrient’s high reactivity and the instability of iron(II) salts. As researchers with backgrounds in material science, chemistry, and food technology, Zhang and Yang leveraged their expertise to develop a solution that could overcome these technical barriers. The fortified coffee serves as a practical example of how NuMOFs can help people increase their iron intake by engaging in a habit that’s already part of their daily routine, with significant potential benefits for women, who are disproportionately affected by iron deficiency. The team plans to expand the technology to incorporate additional nutrients to address a wider array of nutritional deficiencies and improve health equity globally.Fast-track to addressing global health improvementsLooking ahead, Zhang and Yang in the Jaklenec Group are focused on both product commercialization and ongoing research, refining MOFe Coffee to enhance nutrient stability and ensuring the product remains palatable while maximizing iron absorption.Winning the CIC competition means that Zhang, Yang, and the team can fast-track their patent application with the USPTO. The team hopes that their fast-tracked patent will allow them to attract more potential investors and partners, which is crucial for scaling their efforts. A quicker patent process also means that the team can bring the technology to market faster, helping improve global nutrition and health for those who need it most. “Our goal is to make a real difference in addressing micronutrient deficiencies around the world,” says Zhang.   More

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      “Mens et manus” in Guatemala

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      In a new, well-equipped lab at the University del Valle de Guatemala (UVG) in June 2024, members of two Mayan farmers’ cooperatives watched closely as Rodrigo Aragón, professor of mechanical engineering at UVG, demonstrated the operation of an industrial ultrasound machine. Then he invited each of them to test the device.“For us, it is a dream to be able to interact with technology,” said Francisca Elizabeth Saloj Saloj, a member of the Ija´tz women’s collective, a group from Guatemala’s highlands.After a seven-hour bumpy bus ride, the farmers had arrived in Guatemala City with sacks full of rosemary, chamomile, and thyme. Their objective: to explore processes for extracting essential oils from their plants and to identify new products to manufacture with these oils. Currently, farmers sell their herbs in local markets for medicinal or culinary purposes. With new technology, says Aragón, they can add value to their harvest, using herb oils as the basis for perfumes, syrups, and tinctures that would reach broader markets. These goods could provide much-needed income to the farmers’ households.A strategy for transformationThis collaboration is just one part of a five-year, $15-million project funded by the U.S. Agency for International Development (USAID) and managed by MIT’s Department of Mechanical Engineering in collaboration with UVG and the Guatemalan Export Association (AGEXPORT). Launched in 2021 and called ASPIRE — Achieving Sustainable Partnerships for Innovation, Research, and Entrepreneurship — the project aims to collaboratively strengthen UVG, and eventually other universities in Central America, as problem-solving powerhouses that research, design, and build solutions with and for the people most in need.“The vision of ASPIRE is that within a decade, UVG researchers are collaborating with community members on research that generates results that are relevant to addressing local development challenges — results that are picked up and used by policymakers and actors in the private sector,” says MIT Research Scientist Elizabeth Hoffecker, a co-principal investigator of ASPIRE at MIT, and leader of the Institute’s Local Innovation Group.UVG, one of Guatemala’s top universities, has embraced ASPIRE as part of its long-term strategic plan, and is now pursuing wide-ranging changes based on a playbook developed at MIT — including at MIT D-Lab, which deploys participatory design, co-creation, low-cost technologies, and capacity building to meet the complex challenges of poverty — and piloted at UVG. The ASPIRE team is working to extend the reach of its research innovation and entrepreneurship activities to its two regional campuses and to other regional universities. The overall program is informed by MIT’s approach to development of research-driven innovation ecosystems.Although lacking the resources (and PhD programs) of a typical U.S. university, UVG has big ambitions for itself, and for Guatemala.“We want to thrive and lead the country in research and teaching, and to accomplish this, we are creating an innovation and entrepreneurship ecosystem, based on best practices drawn from D-Lab and other MIT groups,” says Mónica Stein, vice-rector for research and outreach at UVG, who holds a doctorate from Stanford University in plant biology. “ASPIRE can really change the way that development work and local research is done so that it has more impact,” says Stein. “And in theory, if you have more impact, then you improve environmental outcomes, health outcomes, educational outcomes, and economic outcomes.”Local innovation and entrepreneurshipShifting gears at a university and launching novel development initiatives are complex challenges, but with training and workshops conducted by D-Lab-trained collaborators and MIT-based ASPIRE staff, UVG faculty, staff, and students are embracing the change. Programs underway should sound familiar to anyone who has set foot recently on the campus of a U.S. research university: hackathons, makerspaces, pitchapaloozas, entrepreneurship competitions, and spinouts. But at UVG, all of these serve a larger purpose: addressing sustainable development goals.ASPIRE principal investigator Daniel Frey, professor of mechanical engineering at MIT, believes some of these programs are already paying off, particularly a UVG venture mentoring service (VMS), modeled after and facilitated by MIT’s own VMS program. “We’d like to see students building companies and improving their livelihoods and those of people from indigenous and marginalized communities,” says Frey.The ASPIRE project intends to enable the lowest-income communities to share more of Guatemala’s wealth, derived mainly from agricultural goods. In collaborating with AGEXPORT, which enables networking with companies across the country, the team zeroed in on creating or enhancing the value chain for several key crops.“Snow peas offer a great target for both research and innovation,” says Adilia Blandón, ASPIRE research project manager and professor of food engineering at UVG. Many farming communities grow snow peas, which they send along to companies for export to the U.S. Unless these peas are perfect in shape and color, Blandón explains, they don’t make it to market. Nearly a third of Guatemala’s crop is left at processing plants, turned into animal feed, or wasted.An ASPIRE snow pea team located farmers from two cooperatives who wanted to solve this problem. At a series of co-creation sessions, these growers and mechanical engineers at UVG developed a prototype for a low-tech cart for collecting snow peas, made from easily acquired local materials, which can navigate the steep and narrow paths on the hills where the plants grow. This method avoids crushing snow peas in a conventional harvest bag. In addition, the snow pea project has engaged women at a technical school to design a harvest apron for women snow pea farmers. “This could be a business opportunity for them,” Blandón says.Blandón vividly recalls her first ASPIRE workshop, focused on participatory design. “It opened my eyes as a researcher in so many ways,” she says. “I learned that instead of taking information from people, I can learn from them and create things with them that they are really excited about.” It completely changed how she approaches research, she says.Working with Mayan communities that produce snow peas, where malnourishment and illness are rampant, Blandón and ASPIRE researchers found that families don’t eat the protein-packed vegetable because they don’t find it palatable — even though so much of it is left over from harvest. Participatory design sessions with a group of mothers yielded an intriguing possibility: grinding snow peas into flour, which would then be incorporated into traditional bean- and corn-based dishes. The recipes born of this collaboration could land on WhatsApp or TikTok, mobile apps familiar to these families.Building value chainsAdditional research projects are teasing out novel ways of adding value to the products grown or made by Guatemalan hands.These include an educational toolkit developed with government farm extension workers to teach avocado producers how to improve their practices. The long-term goal is to grow and export larger and unblemished fruit for the lucrative U.S. market, currently dominated by Mexico. The kit, featuring simple graphics for growers who can’t read or don’t have the time, offers lessons on soil care, fertilizing, and protecting the fruit post-harvest.ASPIRE UVG Research Director Ana Lucia Solano is especially proud of “an immersive, animated, Monopoly-like game that shows farmers the impact of activities like buying fertilizer on their finances,” she says. “If small producers improve their practices, they will have better opportunities to sell their products at a better price, which may allow them to hire more people, teach others more easily, and offer better jobs and working conditions — and maybe this will help prevent farmworkers from having to leave the country.”Solano has just begun a similar program to educate cocoa producers. “The cocoa of Guatemala is wonderful, but the growers, who have great native knowledge, also need to learn new methods so they can transform their chocolate into the kind of high-quality product expected in European markets, with the help of AGEXPORT,” she says.At the UVG Altiplano campus, Mayan instructor Jeremías Morales, who runs the maker space, trained with Amy Smith, an MIT senior lecturer and founding director of the D-Lab, to facilitate creative capacity-building programs. He is working with nearby villages on a solution for the backbreaking labor of planting broccoli seedlings.“Here in Guatemala, small farm holders don’t have technology to do this task,” says Solano. Through design and prototyping workshops, the village and UVG professors have developed an inexpensive device that accomplishes this painful work. “After their next iteration of this technology, we can support the participants in starting a business,” says Solano.Opportunities to invent solutions to commonplace but vexing problems keep popping up. A small village of 100 families has to share two mills to grind corn for their tortillas. It’s a major household expense. With ASPIRE facilitators, a group of women designed a prototype corn mill for home use. “They were skeptical at first, especially when their initial prototypes didn’t work,” reports Solano, “but when they finally succeeded, there was so much excitement about the results, an energy and happiness that you could feel in the room.”Adopting an MIT mindsetThis feeling of empowerment, a pillar of sustainable development, has great meaning for UVG Professor Victor Hugo Ayerdi, an ASPIRE project manager and director of UVG’s Department of Mechanical Engineering.“In college and after I graduated, I thought since everything came from developed countries, and I was in a developing country, I couldn’t invent products.” With that mindset, he says, he went to work in manufacturing and sales for an international tire manufacturing company.But when he arrived at UVG in 2009, Ayerdi heard from mechanical engineering students who craved practical experience designing and building things. Determined to create maker spaces for the three UVG campuses, he took a field trip to MIT, whose motto is “mens et manus” or “mind and hand.”“The trip changed my life,” he says. “The MIT mindset is to believe in yourself, try things, and fail, but assume there has to be a way to do it.” As a result, he says, he realized UVG faculty and students could also use scientific and engineering knowledge to invent products, become entrepreneurs, spark economic growth; they had the capacity. He and other UVG colleagues were primed for change when the ASPIRE opportunity emerged.As some ASPIRE research projects wind down their initial phases, others are just gearing up, including an effort to fashion a water purification system from the shells of farmed shrimp. “We are only just starting to get results from our research,” says Stein. “But we are totally betting on the ASPIRE model because it works at MIT and other places.”The ASPIRE researchers acknowledge they are looking at long timelines to make significant inroads against environmental, health, educational, and economic challenges.“My greatest hope is that ASPIRE will have planted the seed of this innovation and entrepreneurship ecosystem model, and that in a decade, UVG will have optimized the different programs, whether in training, entrepreneurship, or research, enough to actively transfer them to other Central American universities,” says Stein.“We would like to be the hub of this network and we want to stay connected, because, in theory, we can work together on problems that we have in common in our region. That would be really cool.” More

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      in Environment

      Making agriculture more resilient to climate change

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      As Earth’s temperature rises, agricultural practices will need to adapt. Droughts will likely become more frequent, and some land may no longer be arable. On top of that is the challenge of feeding an ever-growing population without expanding the production of fertilizer and other agrochemicals, which have a large carbon footprint that is contributing to the overall warming of the planet.Researchers across MIT are taking on these agricultural challenges from a variety of angles, from engineering plants that sound an alarm when they’re under stress to making seeds more resilient to drought. These types of technologies, and more yet to be devised, will be essential to feed the world’s population as the climate changes.“After water, the first thing we need is food. In terms of priority, there is water, food, and then everything else. As we are trying to find new strategies to support a world of 10 billion people, it will require us to invent new ways of making food,” says Benedetto Marelli, an associate professor of civil and environmental engineering at MIT.Marelli is the director of one of the six missions of the recently launched Climate Project at MIT, which focus on research areas such as decarbonizing industry and building resilient cities. Marelli directs the Wild Cards mission, which aims to identify unconventional solutions that are high-risk and high-reward.Drawing on expertise from a breadth of fields, MIT is well-positioned to tackle the challenges posed by climate change, Marelli says. “Bringing together our strengths across disciplines, including engineering, processing at scale, biological engineering, and infrastructure engineering, along with humanities, science, and economics, presents a great opportunity.”Protecting seeds from droughtMarelli, who began his career as a biomedical engineer working on regenerative medicine, is now developing ways to boost crop yields by helping seeds to survive and germinate during drought conditions, or in soil that has been depleted of nutrients. To achieve that, he has devised seed coatings, based on silk and other polymers, that can envelop and nourish seeds during the critical germination process.

      A new seed-coating process could facilitate agriculture on marginal arid lands by enabling the seeds to retain any available water.

      In healthy soil, plants have access to nitrogen, phosphates, and other nutrients that they need, many of which are supplied by microbes that live in the soil. However, in soil that has suffered from drought or overfarming, these nutrients are lacking. Marelli’s idea was to coat the seeds with a polymer that can be embedded with plant-growth-promoting bacteria that “fix” nitrogen by absorbing it from the air and making it available to plants. The microbes can also make other necessary nutrients available to plants.For the first generation of the seed coatings, he embedded these microbes in coatings made of silk — a material that he had previously shown can extend the shelf life of produce, meat, and other foods. In his lab at MIT, Marelli has shown that the seed coatings can help germinating plants survive drought, ultraviolet light exposure, and high salinity.Now, working with researchers at the Mohammed VI Polytechnic University in Morocco, he is adapting the approach to crops native to Morocco, a country that has experienced six consecutive years of drought due a drop in rainfall linked to climate change.For these studies, the researchers are using a biopolymer coating derived from food waste that can be easily obtained in Morocco, instead of silk.“We’re working with local communities to extract the biopolymers, to try to have a process that works at scale so that we make materials that work in that specific environment.” Marelli says. “We may come up with an idea here at MIT within a high-resource environment, but then to work there, we need to talk with the local communities, with local stakeholders, and use their own ingenuity and try to match our solution with something that could actually be applied in the local environment.”Microbes as fertilizersWhether they are experiencing drought or not, crops grow much better when synthetic fertilizers are applied. Although it’s essential to most farms, applying fertilizer is expensive and has environmental consequences. Most of the world’s fertilizer is produced using the Haber-Bosch process, which converts nitrogen and hydrogen to ammonia at high temperatures and pressures. This energy intensive process accounts for about 1.5 percent of the world’s greenhouse gas emissions, and the transportation required to deliver it to farms around the world adds even more emissions.Ariel Furst, the Paul M. Cook Career Development Assistant Professor of Chemical Engineering at MIT, is developing a microbial alternative to the Haber-Bosch process. Some farms have experimented with applying nitrogen-fixing bacteria directly to the roots of their crops, which has shown some success. However, the microbes are too delicate to be stored long-term or shipped anywhere, so they must be produced in a bioreactor on the farm.

      MIT chemical engineers devised a metal-organic coating that protects bacterial cells from damage without impeding their growth or function.

      To overcome those challenges, Furst has developed a way to coat the microbes with a protective shell that prevents them from being destroyed by heat or other stresses. The coating also protects microbes from damage caused by freeze-drying — a process that would make them easier to transport.The coatings can vary in composition, but they all consist of two components. One is a metal such as iron, manganese, or zinc, and the other is a polyphenol — a type of plant-derived organic compound that includes tannins and other antioxidants. These two components self-assemble into a protective shell that encapsulates bacteria.

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      Mighty Microbes: The Power of Protective PolymersVideo: Chemistry Shorts

      “These microbes would be delivered with the seeds, so it would remove the need for fertilizing mid-growing. It also reduces the cost and provides more autonomy to the farmers and decreases carbon emissions associated with agriculture,” Furst says. “We think it’ll be a way to make agriculture completely regenerative, so to bring back soil health while also boosting crop yields and the nutrient density of the crops.”Furst has founded a company called Seia Bio, which is working on commercializing the coated microbes and has begun testing them on farms in Brazil. In her lab, Furst is also working on adapting the approach to coat microbes that can capture carbon dioxide from the atmosphere and turn it into limestone, which helps to raise the soil pH.“It can help change the pH of soil to stabilize it, while also being a way to effectively perform direct air capture of CO2,” she says. “Right now, farmers may truck in limestone to change the pH of soil, and so you’re creating a lot of emissions to bring something in that microbes can do on their own.”Distress sensors for plantsSeveral years ago, Michael Strano, the Carbon P. Dubbs Professor of Chemical Engineering at MIT, began to explore the idea of using plants themselves as sensors that could reveal when they’re in distress. When plants experience drought, attack by pests, or other kinds of stress, they produce hormones and other signaling molecules to defend themselves.Strano, whose lab specializes in developing tiny sensors for a variety of molecules, wondered if such sensors could be deployed inside plants to pick up those distress signals. To create their sensors, Strano’s lab takes advantage of the special properties of single-walled carbon nanotubes, which emit fluorescent light. By wrapping the tubes with different types of polymers, the sensors can be tuned to detect specific targets, giving off a fluorescent signal when the target is present.For use in plants, Strano and his colleagues created sensors that could detect signaling molecules such as salicylic acid and hydrogen peroxide. They then showed that these sensors could be inserted into the underside of plant leaves, without harming the plants. Once embedded in the mesophyll of the leaves, the sensors can pick up a variety of signals, which can be read with an infrared camera.

      Sensors that detect plant signaling molecules can reveal when crops are experiencing too much light or heat, or attack from insects or microbes.

      These sensors can reveal, in real-time, whether a plant is experiencing a variety of stresses. Until now, there hasn’t been a way to get that information fast enough for farmers to act on it.“What we’re trying to do is make tools that get information into the hands of farmers very quickly, fast enough for them to make adaptive decisions that can increase yield,” Strano says. “We’re in the middle of a revolution of really understanding the way in which plants internally communicate and communicate with other plants.”This kind of sensing could be deployed in fields, where it could help farmers respond more quickly to drought and other stresses, or in greenhouses, vertical farms, and other types of indoor farms that use technology to grow crops in a controlled environment.Much of Strano’s work in this area has been conducted with the support of the U.S. Department of Agriculture (USDA) and as part of the Disruptive and Sustainable Technologies for Agricultural Precision (DiSTAP) program at the Singapore-MIT Alliance for Research and Technology (SMART), and sensors have been deployed in tests in crops at a controlled environment farm in Singapore called Growy.“The same basic kinds of tools can help detect problems in open field agriculture or in controlled environment agriculture,” Strano says. “They both suffer from the same problem, which is that the farmers get information too late to prevent yield loss.”Reducing pesticide usePesticides represent another huge financial expense for farmers: Worldwide, farmers spend about $60 billion per year on pesticides. Much of this pesticide ends up accumulating in water and soil, where it can harm many species, including humans. But, without using pesticides, farmers may lose more than half of their crops.Kripa Varanasi, an MIT professor of mechanical engineering, is working on tools that can help farmers measure how much pesticide is reaching their plants, as well as technologies that can help pesticides adhere to plants more efficiently, reducing the amount that runs off into soil and water.Varanasi, whose research focuses on interactions between liquid droplets and surfaces, began to think about applying his work to agriculture more than a decade ago, after attending a conference at the USDA. There, he was inspired to begin developing ways to improve the efficiency of pesticide application by optimizing the interactions that occur at leaf surfaces.“Billions of drops of pesticide are being sprayed on every acre of crop, and only a small fraction is ultimately reaching and staying on target. This seemed to me like a problem that we could help to solve,” he says.Varanasi and his students began exploring strategies to make drops of pesticide stick to leaves better, instead of bouncing off. They found that if they added polymers with positive and negative charges, the oppositely charged droplets would form a hydrophilic (water-attracting) coating on the leaf surface, which helps the next droplets applied to stick to the leaf.

      AgZen has developed a system for farming that can monitor exactly how much of the sprayed chemicals adheres to plants, in real time, as the sprayer drives through a field.

      Later, they developed an easier-to-use technology in which a surfactant is added to the pesticide before spraying. When this mixture is sprayed through a special nozzle, it forms tiny droplets that are “cloaked” in surfactant. The surfactant helps the droplets to stick to the leaves within a few milliseconds, without bouncing off.In 2020, Varanasi and Vishnu Jayaprakash SM ’19, PhD ’22 founded a company called AgZen to commercialize their technologies and get them into the hands of farmers. They incorporated their ideas for improving pesticide adhesion into a product called EnhanceCoverage.During the testing for this product, they realized that there weren’t any good ways to measure how many of the droplets were staying on the plant. That led them to develop a product known as RealCoverage, which is based on machine vision. It can be attached to any pesticide sprayer and offer real-time feedback on what percentage of the pesticide droplets are sticking to and staying on every leaf.RealCoverage was used on 65,000 acres of farmland across the United States in 2024, from soybeans in Iowa to cotton in Georgia. Farmers who used the product were able to reduce their pesticide use by 30 to 50 percent, by using the data to optimize delivery and, in some cases, even change what chemicals were sprayed.He hopes that the EnhanceCoverage product, which is expected to become available in 2025, will help farmers further reduce their pesticide use.“Our mission here is to help farmers with savings while helping them achieve better yields. We have found a way to do all this while also reducing waste and the amount of chemicals that we put into our atmosphere and into our soils and into our water,” Varanasi says. “This is the MIT approach: to figure out what are the real issues and how to come up with solutions. Now we have a tool and I hope that it’s deployed everywhere and everyone gets the benefit from it.” More

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      in Security

      Uplifting West African communities, one cashew at a time

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      Ever wonder how your favorite snack was sourced? Joshua Reed-Diawuoh thinks more people should.Reed-Diawuoh MBA ’20 is the founder and CEO of GRIA Food Company, which partners with companies that ethically source and process food in West Africa to support local food economies and help communities in the region more broadly.“It’s very difficult for these agribusinesses and producers to start sustainable businesses and build up that value chain in the area,” says Reed-Diawuoh, who started the company as a student in the MIT Sloan School of Management. “We want to support these companies that put in the work to build integrated businesses that are employing people and uplifting communities.”GRIA, which stands for “Grown in Africa,” is currently selling six types of flavored cashews sourced from Benin, Togo, and Burkina Faso. All of the cashews are certified by Fairtrade International, which means in addition to offering sustainable wages, access to financing, and decent working conditions, the companies receive a “Fairtrade Premium” on top of the selling price that allows them to invest in the long-term health of their communities.“That premium is transformational,” Reed-Diawuoh says. “The premium goes to the producer cooperatives, or the farmers working the land, and they can invest that in any way they choose. They can put it back into their business, they can start new community development projects, like building schools or improving wastewater infrastructure, whatever they want.”Cracking the nutReed-Diawuoh’s family is from Ghana, and before coming to MIT Sloan, he worked to support agriculture and food manufacturing for countries in Sub-Saharan Africa, with particular focus on uplifting small-scale farmers. That’s where he learned about difficulties with financing and infrastructure constraints that held many companies back.“I wanted to get my hands dirty and start my own business that contributed to improving agricultural development in West Africa,” Reed-Diawuoh says.He entered MIT Sloan in 2018, taking entrepreneurship classes and exploring several business ideas before deciding to ethically source produce from farmers and sell directly to consumers. He says MIT Sloan’s Sustainability Business Lab offered particularly valuable lessons for how to structure his business.In his second year, Reed-Diawuoh was selected for a fellowship at the Legatum Center, which connected him to other entrepreneurs working in emerging markets around the world.“Legatum was a pivotal milestone for me,” he says. “It provided me with some structure and space to develop this idea. It also gave me an incredible opportunity to take risks and explore different business concepts in a way I couldn’t have done if I was working in industry.”The business model Reed-Diawuoh settled on for GRIA sources product from agribusiness partners in West Africa that adhere to the strictest environmental and labor standards. Reed-Diawuoh decided to start with cashews because they have many manual processing steps — from shelling to peeling and roasting — that are often done after the cashews are shipped out of West Africa, limiting the growth of local food economies and taking wealth out of communities.Each of GRIA’s partners, from the companies harvesting cashews to the processing facilities, works directly with farmer cooperatives and small-scale farmers and is certified by Fairtrade International.“Without proper oversight and regulations, workers oftentimes get exploited, and child labor is a huge problem across the agriculture sector,” Reed-Diawuoh says. “Fairtrade certifications try and take a robust and rigorous approach to auditing all of the businesses and their supply chains, from producers to farmers to processors. They do on-site visits and they audit financial documents. We went through this over the course of a thorough three-month review.”After importing cashew kernels, GRIA flavors and packages them at a production facility in Boston. Reed-Diawuoh started by selling to small independent retailers in Greater Boston before scaling up GRIA’s online sales. He started ramping up production in the beginning of 2023.“Every time we sell our product, if people weren’t already familiar with Fairtrade or ethical sourcing, we provide information on our packaging and all of our collateral,” Reed-Diawuoh says. “We want to spread this message about the importance of ethical sourcing and the importance of building up food manufacturing in West Africa in particular, but also in rising economies throughout the world.”Making ethical sourcing mainstreamGRIA currently imports about a ton of Fairtrade cashews and kernels each quarter, and Reed-Diawuoh hopes to double that number each year for the foreseeable future.“For each pound, we pay premiums for the kernels, and that supports this ecosystem where producers get compensated fairly for their work on the land, and agribusinesses are able to build more robust and profitable business models, because they have an end market for these Fairtrade-certified products.”Reed-Diawuoh is currently trying out different packaging and flavors and is in discussions with partners to expand production capacity and move into Ghana. He’s also exploring corporate collaborations and has provided MIT with product over the past two years for conferences and other events.“We’re experimenting with different growth strategies,” Reed-Diawuoh says. “We’re very much still in startup mode, but really trying to ramp up our sales and production.”As GRIA scales, Reed-Diawuoh hopes it pushes consumers to start asking more of their favorite food brands.“It’s absolutely critical that, if we’re sourcing produce in markets like the U.S. from places like West Africa, we’re hyper-focused on doing it in an ethical manner,” Reed-Diawuoh says. “The overall goal of GRIA is to ensure we are adhering to and promoting strict sourcing standards and being rigorous and thoughtful about the way we import product.” More

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      in Environment

      Translating MIT research into real-world results

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      Inventive solutions to some of the world’s most critical problems are being discovered in labs, classrooms, and centers across MIT every day. Many of these solutions move from the lab to the commercial world with the help of over 85 Institute resources that comprise MIT’s robust innovation and entrepreneurship (I&E) ecosystem. The Abdul Latif Jameel Water and Food Systems Lab (J-WAFS) draws on MIT’s wealth of I&E knowledge and experience to help researchers commercialize their breakthrough technologies through the J-WAFS Solutions grant program. By collaborating with I&E programs on campus, J-WAFS prepares MIT researchers for the commercial world, where their novel innovations aim to improve productivity, accessibility, and sustainability of water and food systems, creating economic, environmental, and societal benefits along the way.The J-WAFS Solutions program launched in 2015 with support from Community Jameel, an international organization that advances science and learning for communities to thrive. Since 2015, J-WAFS Solutions has supported 19 projects with one-year grants of up to $150,000, with some projects receiving renewal grants for a second year of support. Solutions projects all address challenges related to water or food. Modeled after the esteemed grant program of MIT’s Deshpande Center for Technological Innovation, and initially administered by Deshpande Center staff, the J-WAFS Solutions program follows a similar approach by supporting projects that have already completed the basic research and proof-of-concept phases. With technologies that are one to three years away from commercialization, grantees work on identifying their potential markets and learn to focus on how their technology can meet the needs of future customers.“Ingenuity thrives at MIT, driving inventions that can be translated into real-world applications for widespread adoption, implantation, and use,” says J-WAFS Director Professor John H. Lienhard V. “But successful commercialization of MIT technology requires engineers to focus on many challenges beyond making the technology work. MIT’s I&E network offers a variety of programs that help researchers develop technology readiness, investigate markets, conduct customer discovery, and initiate product design and development,” Lienhard adds. “With this strong I&E framework, many J-WAFS Solutions teams have established startup companies by the completion of the grant. J-WAFS-supported technologies have had powerful, positive effects on human welfare. Together, the J-WAFS Solutions program and MIT’s I&E ecosystem demonstrate how academic research can evolve into business innovations that make a better world,” Lienhard says.Creating I&E collaborationsIn addition to support for furthering research, J-WAFS Solutions grants allow faculty, students, postdocs, and research staff to learn the fundamentals of how to transform their work into commercial products and companies. As part of the grant requirements, researchers must interact with mentors through MIT Venture Mentoring Service (VMS). VMS connects MIT entrepreneurs with teams of carefully selected professionals who provide free and confidential mentorship, guidance, and other services to help advance ideas into for-profit, for-benefit, or nonprofit ventures. Since 2000, VMS has mentored over 4,600 MIT entrepreneurs across all industries, through a dynamic and accomplished group of nearly 200 mentors who volunteer their time so that others may succeed. The mentors provide impartial and unbiased advice to members of the MIT community, including MIT alumni in the Boston area. J-WAFS Solutions teams have been guided by 21 mentors from numerous companies and nonprofits. Mentors often attend project events and progress meetings throughout the grant period.“Working with VMS has provided me and my organization with a valuable sounding board for a range of topics, big and small,” says Eric Verploegen PhD ’08, former research engineer in MIT’s D-Lab and founder of J-WAFS spinout CoolVeg. Along with professors Leon Glicksman and Daniel Frey, Verploegen received a J-WAFS Solutions grant in 2021 to commercialize cold-storage chambers that use evaporative cooling to help farmers preserve fruits and vegetables in rural off-grid communities. Verploegen started CoolVeg in 2022 to increase access and adoption of open-source, evaporative cooling technologies through collaborations with businesses, research institutions, nongovernmental organizations, and government agencies. “Working as a solo founder at my nonprofit venture, it is always great to have avenues to get feedback on communications approaches, overall strategy, and operational issues that my mentors have experience with,” Verploegen says. Three years after the initial Solutions grant, one of the VMS mentors assigned to the evaporative cooling team still acts as a mentor to Verploegen today.Another Solutions grant requirement is for teams to participate in the Spark program — a free, three-week course that provides an entry point for researchers to explore the potential value of their innovation. Spark is part of the National Science Foundation’s (NSF) Innovation Corps (I-Corps), which is an “immersive, entrepreneurial training program that facilitates the transformation of invention to impact.” In 2018, MIT received an award from the NSF, establishing the New England Regional Innovation Corps Node (NE I-Corps) to deliver I-Corps training to participants across New England. Trainings are open to researchers, engineers, scientists, and others who want to engage in a customer discovery process for their technology. Offered regularly throughout the year, the Spark course helps participants identify markets and explore customer needs in order to understand how their technologies can be positioned competitively in their target markets. They learn to assess barriers to adoption, as well as potential regulatory issues or other challenges to commercialization. NE-I-Corps reports that since its start, over 1,200 researchers from MIT have completed the program and have gone on to launch 175 ventures, raising over $3.3 billion in funding from grants and investors, and creating over 1,800 jobs.Constantinos Katsimpouras, a research scientist in the Department of Chemical Engineering, went through the NE I-Corps Spark program to better understand the customer base for a technology he developed with professors Gregory Stephanopoulos and Anthony Sinskey. The group received a J-WAFS Solutions grant in 2021 for their microbial platform that converts food waste from the dairy industry into valuable products. “As a scientist with no prior experience in entrepreneurship, the program introduced me to important concepts and tools for conducting customer interviews and adopting a new mindset,” notes Katsimpouras. “Most importantly, it encouraged me to get out of the building and engage in interviews with potential customers and stakeholders, providing me with invaluable insights and a deeper understanding of my industry,” he adds. These interviews also helped connect the team with companies willing to provide resources to test and improve their technology — a critical step to the scale-up of any lab invention.In the case of Professor Cem Tasan’s research group in the Department of Materials Science and Engineering, the I-Corps program led them to the J-WAFS Solutions grant, instead of the other way around. Tasan is currently working with postdoc Onur Guvenc on a J-WAFS Solutions project to manufacture formable sheet metal by consolidating steel scrap without melting, thereby reducing water use compared to traditional steel processing. Before applying for the Solutions grant, Guvenc took part in NE I-Corps. Like Katsimpouras, Guvenc benefited from the interaction with industry. “This program required me to step out of the lab and engage with potential customers, allowing me to learn about their immediate challenges and test my initial assumptions about the market,” Guvenc recalls. “My interviews with industry professionals also made me aware of the connection between water consumption and steelmaking processes, which ultimately led to the J-WAFS 2023 Solutions Grant,” says Guvenc.After completing the Spark program, participants may be eligible to apply for the Fusion program, which provides microgrants of up to $1,500 to conduct further customer discovery. The Fusion program is self-paced, requiring teams to conduct 12 additional customer interviews and craft a final presentation summarizing their key learnings. Professor Patrick Doyle’s J-WAFS Solutions team completed the Spark and Fusion programs at MIT. Most recently, their team was accepted to join the NSF I-Corps National program with a $50,000 award. The intensive program requires teams to complete an additional 100 customer discovery interviews over seven weeks. Located in the Department of Chemical Engineering, the Doyle lab is working on a sustainable microparticle hydrogel system to rapidly remove micropollutants from water. The team’s focus has expanded to higher value purifications in amino acid and biopharmaceutical manufacturing applications. Devashish Gokhale PhD ’24 worked with Doyle on much of the underlying science.“Our platform technology could potentially be used for selective separations in very diverse market segments, ranging from individual consumers to large industries and government bodies with varied use-cases,” Gokhale explains. He goes on to say, “The I-Corps Spark program added significant value by providing me with an effective framework to approach this problem … I was assigned a mentor who provided critical feedback, teaching me how to formulate effective questions and identify promising opportunities.” Gokhale says that by the end of Spark, the team was able to identify the best target markets for their products. He also says that the program provided valuable seminars on topics like intellectual property, which was helpful in subsequent discussions the team had with MIT’s Technology Licensing Office.Another member of Doyle’s team, Arjav Shah, a recent PhD from MIT’s Department of Chemical Engineering and a current MBA candidate at the MIT Sloan School of Management, is spearheading the team’s commercialization plans. Shah attended Fusion last fall and hopes to lead efforts to incorporate a startup company called hydroGel.  “I admire the hypothesis-driven approach of the I-Corps program,” says Shah. “It has enabled us to identify our customers’ biggest pain points, which will hopefully lead us to finding a product-market fit.” He adds “based on our learnings from the program, we have been able to pivot to impact-driven, higher-value applications in the food processing and biopharmaceutical industries.” Postdoc Luca Mazzaferro will lead the technical team at hydroGel alongside Shah.In a different project, Qinmin Zheng, a postdoc in the Department of Civil and Environmental Engineering, is working with Professor Andrew Whittle and Lecturer Fábio Duarte. Zheng plans to take the Fusion course this fall to advance their J-WAFS Solutions project that aims to commercialize a novel sensor to quantify the relative abundance of major algal species and provide early detection of harmful algal blooms. After completing Spark, Zheng says he’s “excited to participate in the Fusion program, and potentially the National I-Corps program, to further explore market opportunities and minimize risks in our future product development.”Economic and societal benefitsCommercializing technologies developed at MIT is one of the ways J-WAFS helps ensure that MIT research advances will have real-world impacts in water and food systems. Since its inception, the J-WAFS Solutions program has awarded 28 grants (including renewals), which have supported 19 projects that address a wide range of global water and food challenges. The program has distributed over $4 million to 24 professors, 11 research staff, 15 postdocs, and 30 students across MIT. Nearly half of all J-WAFS Solutions projects have resulted in spinout companies or commercialized products, including eight companies to date plus two open-source technologies.Nona Technologies is an example of a J-WAFS spinout that is helping the world by developing new approaches to produce freshwater for drinking. Desalination — the process of removing salts from seawater — typically requires a large-scale technology called reverse osmosis. But Nona created a desalination device that can work in remote off-grid locations. By separating salt and bacteria from water using electric current through a process called ion concentration polarization (ICP), their technology also reduces overall energy consumption. The novel method was developed by Jongyoon Han, professor of electrical engineering and biological engineering, and research scientist Junghyo Yoon. Along with Bruce Crawford, a Sloan MBA alum, Han and Yoon created Nona Technologies to bring their lightweight, energy-efficient desalination technology to the market.“My feeling early on was that once you have technology, commercialization will take care of itself,” admits Crawford. The team completed both the Spark and Fusion programs and quickly realized that much more work would be required. “Even in our first 24 interviews, we learned that the two first markets we envisioned would not be viable in the near term, and we also got our first hints at the beachhead we ultimately selected,” says Crawford. Nona Technologies has since won MIT’s $100K Entrepreneurship Competition, received media attention from outlets like Newsweek and Fortune, and hired a team that continues to further the technology for deployment in resource-limited areas where clean drinking water may be scarce. Food-borne diseases sicken millions of people worldwide each year, but J-WAFS researchers are addressing this issue by integrating molecular engineering, nanotechnology, and artificial intelligence to revolutionize food pathogen testing. Professors Tim Swager and Alexander Klibanov, of the Department of Chemistry, were awarded one of the first J-WAFS Solutions grants for their sensor that targets food safety pathogens. The sensor uses specialized droplets that behave like a dynamic lens, changing in the presence of target bacteria in order to detect dangerous bacterial contamination in food. In 2018, Swager launched Xibus Systems Inc. to bring the sensor to market and advance food safety for greater public health, sustainability, and economic security.“Our involvement with the J-WAFS Solutions Program has been vital,” says Swager. “It has provided us with a bridge between the academic world and the business world and allowed us to perform more detailed work to create a usable application,” he adds. In 2022, Xibus developed a product called XiSafe, which enables the detection of contaminants like salmonella and listeria faster and with higher sensitivity than other food testing products. The innovation could save food processors billions of dollars worldwide and prevent thousands of food-borne fatalities annually.J-WAFS Solutions companies have raised nearly $66 million in venture capital and other funding. Just this past June, J-WAFS spinout SiTration announced that it raised an $11.8 million seed round. Jeffrey Grossman, a professor in MIT’s Department of Materials Science and Engineering, was another early J-WAFS Solutions grantee for his work on low-cost energy-efficient filters for desalination. The project enabled the development of nanoporous membranes and resulted in two spinout companies, Via Separations and SiTration. SiTration was co-founded by Brendan Smith PhD ’18, who was a part of the original J-WAFS team. Smith is CEO of the company and has overseen the advancement of the membrane technology, which has gone on to reduce cost and resource consumption in industrial wastewater treatment, advanced manufacturing, and resource extraction of materials such as lithium, cobalt, and nickel from recycled electric vehicle batteries. The company also recently announced that it is working with the mining company Rio Tinto to handle harmful wastewater generated at mines.But it’s not just J-WAFS spinout companies that are producing real-world results. Products like the ECC Vial — a portable, low-cost method for E. coli detection in water — have been brought to the market and helped thousands of people. The test kit was developed by MIT D-Lab Lecturer Susan Murcott and Professor Jeffrey Ravel of the MIT History Section. The duo received a J-WAFS Solutions grant in 2018 to promote safely managed drinking water and improved public health in Nepal, where it is difficult to identify which wells are contaminated by E. coli. By the end of their grant period, the team had manufactured approximately 3,200 units, of which 2,350 were distributed — enough to help 12,000 people in Nepal. The researchers also trained local Nepalese on best manufacturing practices.“It’s very important, in my life experience, to follow your dream and to serve others,” says Murcott. Economic success is important to the health of any venture, whether it’s a company or a product, but equally important is the social impact — a philosophy that J-WAFS research strives to uphold. “Do something because it’s worth doing and because it changes people’s lives and saves lives,” Murcott adds.As J-WAFS prepares to celebrate its 10th anniversary this year, we look forward to continued collaboration with MIT’s many I&E programs to advance knowledge and develop solutions that will have tangible effects on the world’s water and food systems.Learn more about the J-WAFS Solutions program and about innovation and entrepreneurship at MIT. More

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      in Security

      Study reveals the benefits and downside of fasting

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      Low-calorie diets and intermittent fasting have been shown to have numerous health benefits: They can delay the onset of some age-related diseases and lengthen lifespan, not only in humans but many other organisms.Many complex mechanisms underlie this phenomenon. Previous work from MIT has shown that one way fasting exerts its beneficial effects is by boosting the regenerative abilities of intestinal stem cells, which helps the intestine recover from injuries or inflammation.In a study of mice, MIT researchers have now identified the pathway that enables this enhanced regeneration, which is activated once the mice begin “refeeding” after the fast. They also found a downside to this regeneration: When cancerous mutations occurred during the regenerative period, the mice were more likely to develop early-stage intestinal tumors.“Having more stem cell activity is good for regeneration, but too much of a good thing over time can have less favorable consequences,” says Omer Yilmaz, an MIT associate professor of biology, a member of MIT’s Koch Institute for Integrative Cancer Research, and the senior author of the new study.Yilmaz adds that further studies are needed before forming any conclusion as to whether fasting has a similar effect in humans.“We still have a lot to learn, but it is interesting that being in either the state of fasting or refeeding when exposure to mutagen occurs can have a profound impact on the likelihood of developing a cancer in these well-defined mouse models,” he says.MIT postdocs Shinya Imada and Saleh Khawaled are the lead authors of the paper, which appears today in Nature.Driving regenerationFor several years, Yilmaz’s lab has been investigating how fasting and low-calorie diets affect intestinal health. In a 2018 study, his team reported that during a fast, intestinal stem cells begin to use lipids as an energy source, instead of carbohydrates. They also showed that fasting led to a significant boost in stem cells’ regenerative ability.However, unanswered questions remained: How does fasting trigger this boost in regenerative ability, and when does the regeneration begin?“Since that paper, we’ve really been focused on understanding what is it about fasting that drives regeneration,” Yilmaz says. “Is it fasting itself that’s driving regeneration, or eating after the fast?”In their new study, the researchers found that stem cell regeneration is suppressed during fasting but then surges during the refeeding period. The researchers followed three groups of mice — one that fasted for 24 hours, another one that fasted for 24 hours and then was allowed to eat whatever they wanted during a 24-hour refeeding period, and a control group that ate whatever they wanted throughout the experiment.The researchers analyzed intestinal stem cells’ ability to proliferate at different time points and found that the stem cells showed the highest levels of proliferation at the end of the 24-hour refeeding period. These cells were also more proliferative than intestinal stem cells from mice that had not fasted at all.“We think that fasting and refeeding represent two distinct states,” Imada says. “In the fasted state, the ability of cells to use lipids and fatty acids as an energy source enables them to survive when nutrients are low. And then it’s the postfast refeeding state that really drives the regeneration. When nutrients become available, these stem cells and progenitor cells activate programs that enable them to build cellular mass and repopulate the intestinal lining.”Further studies revealed that these cells activate a cellular signaling pathway known as mTOR, which is involved in cell growth and metabolism. One of mTOR’s roles is to regulate the translation of messenger RNA into protein, so when it’s activated, cells produce more protein. This protein synthesis is essential for stem cells to proliferate.The researchers showed that mTOR activation in these stem cells also led to production of large quantities of polyamines — small molecules that help cells to grow and divide.“In the refed state, you’ve got more proliferation, and you need to build cellular mass. That requires more protein, to build new cells, and those stem cells go on to build more differentiated cells or specialized intestinal cell types that line the intestine,” Khawaled says.Too much of a good thingThe researchers also found that when stem cells are in this highly regenerative state, they are more prone to become cancerous. Intestinal stem cells are among the most actively dividing cells in the body, as they help the lining of the intestine completely turn over every five to 10 days. Because they divide so frequently, these stem cells are the most common source of precancerous cells in the intestine.In this study, the researchers discovered that if they turned on a cancer-causing gene in the mice during the refeeding stage, they were much more likely to develop precancerous polyps than if the gene was turned on during the fasting state. Cancer-linked mutations that occurred during the refeeding state were also much more likely to produce polyps than mutations that occurred in mice that did not undergo the cycle of fasting and refeeding.“I want to emphasize that this was all done in mice, using very well-defined cancer mutations. In humans it’s going to be a much more complex state,” Yilmaz says. “But it does lead us to the following notion: Fasting is very healthy, but if you’re unlucky and you’re refeeding after a fasting, and you get exposed to a mutagen, like a charred steak or something, you might actually be increasing your chances of developing a lesion that can go on to give rise to cancer.”Yilmaz also noted that the regenerative benefits of fasting could be significant for people who undergo radiation treatment, which can damage the intestinal lining, or other types of intestinal injury. His lab is now studying whether polyamine supplements could help to stimulate this kind of regeneration, without the need to fast.“This fascinating study provides insights into the complex interplay between food consumption, stem cell biology, and cancer risk,” says Ophir Klein, a professor of medicine at the University of California at San Francisco and Cedars-Sinai Medical Center, who was not involved in the study. “Their work lays a foundation for testing polyamines as compounds that may augment intestinal repair after injuries, and it suggests that careful consideration is needed when planning diet-based strategies for regeneration to avoid increasing cancer risk.”The research was funded, in part, by a Pew-Stewart Trust Scholar award, the Marble Center for Cancer Nanomedicine, the Koch Institute-Dana Farber/Harvard Cancer Center Bridge Project, and the MIT Stem Cell Initiative. More

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      in Environment

      MIT School of Science launches Center for Sustainability Science and Strategy

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      The MIT School of Science is launching a center to advance knowledge and computational capabilities in the field of sustainability science, and support decision-makers in government, industry, and civil society to achieve sustainable development goals. Aligned with the Climate Project at MIT, researchers at the MIT Center for Sustainability Science and Strategy will develop and apply expertise from across the Institute to improve understanding of sustainability challenges, and thereby provide actionable knowledge and insight to inform strategies for improving human well-being for current and future generations.Noelle Selin, professor at MIT’s Institute for Data, Systems and Society and the Department of Earth, Atmospheric and Planetary Sciences, will serve as the center’s inaugural faculty director. C. Adam Schlosser and Sergey Paltsev, senior research scientists at MIT, will serve as deputy directors, with Anne Slinn as executive director.Incorporating and succeeding both the Center for Global Change Science and Joint Program on the Science and Policy of Global Change while adding new capabilities, the center aims to produce leading-edge research to help guide societal transitions toward a more sustainable future. Drawing on the long history of MIT’s efforts to address global change and its integrated environmental and human dimensions, the center is well-positioned to lead burgeoning global efforts to advance the field of sustainability science, which seeks to understand nature-society systems in their full complexity. This understanding is designed to be relevant and actionable for decision-makers in government, industry, and civil society in their efforts to develop viable pathways to improve quality of life for multiple stakeholders.“As critical challenges such as climate, health, energy, and food security increasingly affect people’s lives around the world, decision-makers need a better understanding of the earth in its full complexity — and that includes people, technologies, and institutions as well as environmental processes,” says Selin. “Better knowledge of these systems and how they interact can lead to more effective strategies that avoid unintended consequences and ensure an improved quality of life for all.”    Advancing knowledge, computational capability, and decision supportTo produce more precise and comprehensive knowledge of sustainability challenges and guide decision-makers to formulate more effective strategies, the center has set the following goals:Advance fundamental understanding of the complex interconnected physical and socio-economic systems that affect human well-being. As new policies and technologies are developed amid climate and other global changes, they interact with environmental processes and institutions in ways that can alter the earth’s critical life-support systems. Fundamental mechanisms that determine many of these systems’ behaviors, including those related to interacting climate, water, food, and socio-economic systems, remain largely unknown and poorly quantified. Better understanding can help society mitigate the risks of abrupt changes and “tipping points” in these systems.Develop, establish and disseminate new computational tools toward better understanding earth systems, including both environmental and human dimensions. The center’s work will integrate modeling and data analysis across disciplines in an era of increasing volumes of observational data. MIT multi-system models and data products will provide robust information to inform decision-making and shape the next generation of sustainability science and strategy.Produce actionable science that supports equity and justice within and across generations. The center’s research will be designed to inform action associated with measurable outcomes aligned with supporting human well-being across generations. This requires engaging a broad range of stakeholders, including not only nations and companies, but also nongovernmental organizations and communities that take action to promote sustainable development — with special attention to those who have historically borne the brunt of environmental injustice.“The center’s work will advance fundamental understanding in sustainability science, leverage leading-edge computing and data, and promote engagement and impact,” says Selin. “Our researchers will help lead scientists and strategists across the globe who share MIT’s commitment to mobilizing knowledge to inform action toward a more sustainable world.”Building a better world at MITBuilding on existing MIT capabilities in sustainability, science, and strategy, the center aims to: focus research, education, and outreach under a theme that reflects a comprehensive state of the field and international research directions, fostering a dynamic community of students, researchers, and faculty;raise the visibility of sustainability science at MIT, emphasizing links between science and action, in the context of existing Institute goals and other efforts on climate and sustainability, and in a way that reflects the vital contributions of a range of natural and social science disciplines to understanding human-environment systems; andre-emphasize MIT’s long-standing expertise in integrated systems modeling while leveraging the Institute’s concurrent leading-edge strengths in data and computing, establishing leadership that harnesses recent innovations, including those in machine learning and artificial intelligence, toward addressing the science challenges of global change and sustainability.“The Center for Sustainability Science and Strategy will provide the necessary synergy for our MIT researchers to develop, deploy, and scale up serious solutions to climate change and other critical sustainability challenges,” says Nergis Mavalvala, the Curtis and Kathleen Marble Professor of Astrophysics and dean of the MIT School of Science. “With Professor Selin at its helm, the center will also ensure that these solutions are created in concert with the people who are directly affected now and in the future.”The center builds on more than three decades of achievements by the Center for Global Change Science and the Joint Program on the Science and Policy of Global Change, both of which were directed or co-directed by professor of atmospheric science Ronald Prinn. More

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      in Environment

      Advancing technology for aquaculture

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      According to the National Oceanic and Atmospheric Administration, aquaculture in the United States represents a $1.5 billion industry annually. Like land-based farming, shellfish aquaculture requires healthy seed production in order to maintain a sustainable industry. Aquaculture hatchery production of shellfish larvae — seeds — requires close monitoring to track mortality rates and assess health from the earliest stages of life. 

      Careful observation is necessary to inform production scheduling, determine effects of naturally occurring harmful bacteria, and ensure sustainable seed production. This is an essential step for shellfish hatcheries but is currently a time-consuming manual process prone to human error. 

      With funding from MIT’s Abdul Latif Jameel Water and Food Systems Lab (J-WAFS), MIT Sea Grant is working with Associate Professor Otto Cordero of the MIT Department of Civil and Environmental Engineering, Professor Taskin Padir and Research Scientist Mark Zolotas at the Northeastern University Institute for Experiential Robotics, and others at the Aquaculture Research Corporation (ARC), and the Cape Cod Commercial Fishermen’s Alliance, to advance technology for the aquaculture industry. Located on Cape Cod, ARC is a leading shellfish hatchery, farm, and wholesaler that plays a vital role in providing high-quality shellfish seed to local and regional growers.

      Two MIT students have joined the effort this semester, working with Robert Vincent, MIT Sea Grant’s assistant director of advisory services, through the Undergraduate Research Opportunities Program (UROP). 

      First-year student Unyime Usua and sophomore Santiago Borrego are using microscopy images of shellfish seed from ARC to train machine learning algorithms that will help automate the identification and counting process. The resulting user-friendly image recognition tool aims to aid aquaculturists in differentiating and counting healthy, unhealthy, and dead shellfish larvae, improving accuracy and reducing time and effort.

      Vincent explains that AI is a powerful tool for environmental science that enables researchers, industry, and resource managers to address challenges that have long been pinch points for accurate data collection, analysis, predictions, and streamlining processes. “Funding support from programs like J-WAFS enable us to tackle these problems head-on,” he says. 

      ARC faces challenges with manually quantifying larvae classes, an important step in their seed production process. “When larvae are in their growing stages they are constantly being sized and counted,” explains Cheryl James, ARC larval/juvenile production manager. “This process is critical to encourage optimal growth and strengthen the population.” 

      Developing an automated identification and counting system will help to improve this step in the production process with time and cost benefits. “This is not an easy task,” says Vincent, “but with the guidance of Dr. Zolotas at the Northeastern University Institute for Experiential Robotics and the work of the UROP students, we have made solid progress.” 

      The UROP program benefits both researchers and students. Involving MIT UROP students in developing these types of systems provides insights into AI applications that they might not have considered, providing opportunities to explore, learn, and apply themselves while contributing to solving real challenges.

      Borrego saw this project as an opportunity to apply what he’d learned in class 6.390 (Introduction to Machine Learning) to a real-world issue. “I was starting to form an idea of how computers can see images and extract information from them,” he says. “I wanted to keep exploring that.”

      Usua decided to pursue the project because of the direct industry impacts it could have. “I’m pretty interested in seeing how we can utilize machine learning to make people’s lives easier. We are using AI to help biologists make this counting and identification process easier.” While Usua wasn’t familiar with aquaculture before starting this project, she explains, “Just hearing about the hatcheries that Dr. Vincent was telling us about, it was unfortunate that not a lot of people know what’s going on and the problems that they’re facing.”

      On Cape Cod alone, aquaculture is an $18 million per year industry. But the Massachusetts Division of Marine Fisheries estimates that hatcheries are only able to meet 70–80 percent of seed demand annually, which impacts local growers and economies. Through this project, the partners aim to develop technology that will increase seed production, advance industry capabilities, and help understand and improve the hatchery microbiome.

      Borrego explains the initial challenge of having limited data to work with. “Starting out, we had to go through and label all of the data, but going through that process helped me learn a lot.” In true MIT fashion, he shares his takeaway from the project: “Try to get the best out of what you’re given with the data you have to work with. You’re going to have to adapt and change your strategies depending on what you have.”

      Usua describes her experience going through the research process, communicating in a team, and deciding what approaches to take. “Research is a difficult and long process, but there is a lot to gain from it because it teaches you to look for things on your own and find your own solutions to problems.”

      In addition to increasing seed production and reducing the human labor required in the hatchery process, the collaborators expect this project to contribute to cost savings and technology integration to support one of the most underserved industries in the United States. 

      Borrego and Usua both plan to continue their work for a second semester with MIT Sea Grant. Borrego is interested in learning more about how technology can be used to protect the environment and wildlife. Usua says she hopes to explore more projects related to aquaculture. “It seems like there’s an infinite amount of ways to tackle these issues.” More