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      in Environment

      How molecular biology could reduce global food insecurity

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      Staple crops like rice, maize, and wheat feed over half of the global population, but they are increasingly vulnerable to severe environmental risks. The effects of climate change, including changing temperatures, rainfall variability, shifting patterns of agricultural pests and diseases, and saltwater intrusion from sea-level rise, all contribute to decreased crop yields. As these effects continue to worsen, there will be less food available for a rapidly growing population. 

      Mary Gehring, associate professor of biology and a member of the Whitehead Institute for Biomedical Research, is growing increasingly concerned about the potentially catastrophic impacts of climate change and has resolved to do something about it.

      The Gehring Lab’s primary research focus is plant epigenetics, which refers to the heritable information that influences plant cellular function but is not encoded in the DNA sequence itself. This research is adding to our fundamental understanding of plant biology and could have agricultural applications in the future. “I’ve been working with seeds for many years,” says Gehring. “Understanding how seeds work is going to be critical to agriculture and food security,” she explains.

      Laying the foundation

      Gehring is using her expertise to help crops develop climate resilience through a 2021 seed grant from MIT’s Abdul Latif Jameel Water and Food Systems Lab (J-WAFS). Her research is aimed at discovering how we can accelerate the production of genetic diversity to generate plant populations that are better suited to challenging environmental conditions.

      Genetic variation gives rise to phenotypic variations that can help plants adapt to a wider range of climates. Traits such as flood resistance and salt tolerance will become more important as the effects of climate change are realized. However, many important plant species do not appear to have much standing genetic variation, which could become an issue if farmers need to breed their crops quickly to adapt to a changing climate. 

      In researching a nutritious crop that has little genetic variation, Gehring came across the pigeon pea, a species she had never worked with before. Pigeon peas are a legume eaten in Asia, Africa, and Latin America. They have some of the highest levels of protein in a seed, so eating more pigeon peas could decrease our dependence on meat, which has numerous negative environmental impacts. Pigeon peas also have a positive impact on the environment; as perennial plants, they live for three to five years and sequester carbon for longer periods of time. They can also help with soil restoration. “Legumes are very interesting because they’re nitrogen-fixers, so they create symbioses with microbes in the soil and fix nitrogen, which can renew soils,” says Gehring. Furthermore, pigeon peas are known to be drought-resistant, so they will likely become more attractive as many farmers transition away from water-intensive crops.

      Developing a strategy

      Using the pigeon pea plant, Gehring began to explore a universal technology that would increase the amount of genetic diversity in plants. One method her research group chose is to enhance transposable element proliferation. Genomes are made up of genes that make proteins, but large fractions are also made up of transposable elements. In fact, about 45 percent of the human genome is made up of transposable elements, Gehring notes. The primary function of transposable elements is to make more copies of themselves. Since our bodies do not need an infinite number of these copies, there are systems in place to “silence” them from copying. 

      Gehring is trying to reverse that silencing so that the transposable elements can move freely throughout the genome, which could create genetic variation by creating mutations or altering the promoter of a gene — that is, what controls a certain gene’s expression. Scientists have traditionally initiated mutagenesis by using a chemical that changes single base pairs in DNA, or by using X-rays, which can cause very large chromosome breaks. Gehring’s research team is attempting to induce transposable element proliferation by treatment with a suite of chemicals that inhibit transposable element silencing. The goal is to impact multiple sites in the genome simultaneously. “This is unexplored territory where you’re changing 50 genes at a time, or 100, rather than just one,” she explains. “It’s a fairly risky project, but sometimes you have to be ambitious and take risks.”

      Looking forward

      Less than one year after receiving the J-WAFS seed grant, the research project is still in its early stages. Despite various restrictions due to the ongoing pandemic, the Gehring Lab is now generating data on the Arabidopsis plant that will be applied to pigeon pea plants. However, Gehring expects it will take a good amount of time to complete this research phase, considering the pigeon pea plants can take upward of 100 days just to flower. While it might take time, this technology could help crops withstand the effects of climate change, ultimately contributing to J-WAFS’ goal of finding solutions to food system challenges.

      “Climate change is not something any of us can ignore. … If one of us has the ability to address it, even in a very small way, that’s important to try to pursue,” Gehring remarks. “It’s part of our responsibility as scientists to take what knowledge we have and try to apply it to these sorts of problems.” More

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      Progress toward a sustainable campus food system

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      As part of MIT’s updated climate action plan, known as “Fast Forward,” Institute leadership committed to establishing a set of quantitative goals in 2022 related to food, water, and waste systems that advance MIT’s commitment to climate. Moving beyond the impact of campus energy systems, these newly proposed goals take a holistic view of the drivers of climate change and set the stage for new frontiers of collaborative climate work. “With the release of ‘Fast Forward,’ the MIT Office of Sustainability is setting out to partner with campus groups to study and quantify the climate impact of our campus food, while deeply considering the social, cultural, economic, and health aspects of a sustainable food system,” explains Susy Jones, senior sustainability project manager. 

      While “Fast Forward” is MIT’s first climate action plan to integrate the campus food system, the Division of Student Life (DSL) has long worked with dining vendors, MIT’s Office of Sustainability (MITOS), and other campus partners to advance a more sustainable, affordable, and equitable food system. Initiatives have ranged from increasing access to low-cost groceries on and around campus to sourcing sustainable coffee for campus cafes.

      Even with the complexities of operating during the pandemic, efforts in this area accelerated with the launch of new partnerships, support for local food industries, and even a food-startup incubator in the Stratton Student Center (Building W20). “Despite challenges posed by the pandemic, MIT Dining has been focused on positive change — driven in part by student input, alterations to the food landscape, and our ongoing goal to support a more sustainable and equitable campus food system,” says Mark Hayes, director of MIT Dining.

      New vendors on campus focus on healthy food systems

      For many, a fresh cup of coffee is a daily ritual. At MIT, that cup of coffee also offers an opportunity to make a more sustainable choice at the Forbes Family Café in the Stata Center (Building 32). The cafe now brews coffee by Dean’s Beans, a local roaster whose mission is to “prove that a for-profit business could create meaningful change through ethical business practices rooted in respect for the earth, the farmer, our co-workers, and the consumer.” The choice of Dean’s Beans — a certified B Corporation located in Orange, Massachusetts — as the new vendor in this space helps advance MIT’s commitment to sustainability. Businesses that achieve this certification meet rigorous social and environmental goals. “With choices like this, we’re taking big issues down to the campus level,” says Hayes. Dean’s Beans focuses on long-term producer relationships, organic shade-grown and bird-friendly coffee, a solar-powered roasting facility, and people-centered development programs. These practices contribute to healthier environments and habitats — benefiting farmers, soils, birds, pollinators, and more.

      Another innovative new food concept for the MIT community can be found down the street in the Stratton Student Center. The Launchpad, a nonprofit food business incubator created in partnership with CommonWealth Kitchen (CWK), debuted this fall in the second-floor Lobdell Food Court. It offers the MIT community more variety and healthy food options while also “advancing CWK’s and MIT’s mutual goal to support diverse, local start-up food businesses and to create a more just, equitable, and sustainable food economy,” according to DSL. Work on the Launchpad began in 2018, bringing together the Student Center Dining Concepts Working Group, comprising students from the Undergraduate Association, Graduate Student Council, DormCon, house dining chairs, and other students interested in dining and dining staff from the MITOS and DSL. Their goal was to re-envision dining options available in Lobdell to support local, diverse, and sustainable menus. “We’ve been nurturing a partnership with CommonWealth Kitchen for years and are excited to partner with them on a project that re-imagines the relationship between campus and local food systems,” says Jones. “And, of course, the vegetarian arepas are a highlight,” she adds.

      Local partnerships for sustainability

      The impacts of Covid-19 on local food businesses quickly came into focus in early 2020. For the New England fishing industry, this impact was acute — with restaurant closures, event cancellations, and disruptions in the global supply chain, fisheries suddenly found a dearth of markets for their catch, undermining their source of income. One way to address this confluence of challenges was for fisheries to expand into new markets where they may have had limited knowledge or experience.

      Enter MIT Sea Grant and MIT Dining. Supported in part by funding from the National Oceanic and Atmospheric Administration, MIT Sea Grant created the Covid-19 Rapid Response Program to develop new markets for local fisheries, including local food banks and direct sales to organizations including MIT. Though MIT Dining was stretched thin by the pandemic, the partnership offered a singular opportunity to support vital regional businesses and enhance menus in campus dining venues. “The stress level was unimaginable as more people were testing positive in the early days of the pandemic — it was the worst and most stressful time to do anything outside of what was completely necessary, and I get this phone call about chowder,” recalls Hayes. “Everyone is wearing two masks and standing six feet apart, but in about 15 seconds, I said to myself, ‘This is the exact time this needs to happen — in the middle of a pandemic when fishermen need support, families need support, people need support.’”

      Shortly after getting the call, Hayes and MIT Dining hosted a tasting event featuring “Small Boats, Big Taste Haddock Chowder,” developed through MIT Sea Grant’s work with the Cape Cod Commercial Fishermen’s Alliance, which helped independent fishermen stay on the water during Covid-19. The tasting event also offered students a break to stop by and sample the chowder, which later debuted and continues to be served at MIT dining halls. For Hayes, one success of the partnership was the agility it demonstrated. “We don’t know what the next crisis is going to be, but these experiences will make us stronger to handle the next moment when people need the food system to work,” he says.

      In addition to ready-made options for students, MIT Dining and partners have also been working to support students who prepare their own meals, collaborating with local businesses to provide students access to lower-cost and at-cost groceries and food products. The Food Security Action Team, convened by Senior Associate Dean for Student Support and Well-being David Randall and DSL Executive Director for Administration Peter Cummings, is focused on taking action, tracking, and updating the community on food security efforts. These efforts have included collaborating with the Daily Table, a new nonprofit community grocer in Central Square. The store now accepts TechCASH and recently worked with the committee to host an interactive food tour for students.

      Because food systems are so interdependent and partnerships are critical — on and off campus — Hayes says it’s important to continue to share and learn. “Sharing our stories is crucial because we can help strengthen networks of campuses, institutions, and businesses in New England to grow more sustainable food programs like these.” More

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      in Security

      MIT students explore food sustainability

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      As students approached the homestretch of the fall semester, many were focused on completing final projects and preparing for exams. During this time of year, some students may neglect their well-being to the point of skipping meals. To help alleviate end-of-term stress and to give students a delicious study break, the Food Security Action Team recently offered a group of first-year students the opportunity to join a food tour of Daily Table, a new grocer located in Cambridge’s Central Square.

      Seventeen students along with staff from Student Financial Services, Office of the First Year, and the Office of Sustainability led the group from the steps of 77 Massachusetts Avenue a few blocks down the street to Daily Table in Central Square. As part of participating in the program, students were given a $25 TechCash gift card to shop for grocery items during the trip. To make things even more fun, MIT staff created a recipe challenge to encourage students to work together on making their own variation of quesadillas.

      Healthy, affordable, sustainable

      At Daily Table, students were greeted by Celia Grant, director of community engagement and programs from Daily Table, who led them through a tour of the space and highlighted the history and model of the grocery store, as well as some of its unique features. Founded by former Trader Joe’s president Doug Rauch in 2015, Daily Table operates three retail stores in Dorchester, Roxbury, and Central Square, and a commissary kitchen in the Boston metro area. Two more stores are in the works: one in Mattapan and another in Salem. For added convenience, Daily Table also offers free grocery delivery within a two-mile radius of its three locations.

      The Daily Table’s ethos is that delicious and wholesome food should be available, accessible, and affordable for everyone. To achieve these goals, Daily Table provides a wide selection of fresh produce, nutritious grocery staples, and made-from-scratch prepared grab-n-go foods at affordable prices. “All of our products meet strict nutritional guidelines for sodium and sugar so that customers can make food choices based on their diets, not based on price,” says Grant.

      In addition to a large network of farmers, manufacturers, and distributors who supply food to their stores, Daily Table often recovers and rescues perfectly good food that would have otherwise been sent to landfills. Surplus food, packaging and/or label changes, and items with close expiration dates are often discarded by larger grocery stores in the supply chain. But Daily Table steps in to break this cycle of waste and sell these products to customers at a much lower cost. 

      The pandemic has uncovered how difficult it can be for individuals and families to budget for necessities like utilities, rent, and even food. Daily Table seeks to create a more sustainable future by providing access to more well-balanced, nutritious food. “Even before the pandemic, it was challenging for families on limited incomes to meet the nutrition needs of their families. Post-pandemic, this challenge has now encompassed even more households, even those that have never before been challenged in this way,” says Grant. “As winter moves through, and inflation increases, the need for more affordable food and nutrition will rise. Daily Table is prepared to help meet those needs, and more.” 

      Food resources at MIT

      Downstairs at the Daily Table Central Square store, MIT staff members led a discussion about the components of a sustainable food system at MIT and beyond, shared advice on how to budget for food, and offered tips on how to make grocery shopping or cooking fun with fellow classmates and peers. “Shopping at Daily Table provides an experiential case study in solving for multiple goals at once — from the environmental impacts of food waste to healthy eating to affordability — an important framework to consider when tackling climate challenges.” says Susy Jones, senior sustainability project manager in the MIT Office of Sustainability.

      The group also discussed budgeting expenses, including food. “By taking students to the grocery store and providing some small but meaningful tips, we provided them the opportunity to put their learning into practice!” says Erica Aguiar, associate director for financial education in Student Financial Services. “We saw students taking a closer look at prices and even coming together to share groceries.”

      MIT senior and DormCon Dining Chair Ashley Holton shared her grocery shopping strategies with the group, and how she utilizes resources available at MIT. “Having a plan before you enter the grocery store is really important,” says Holton. “Not only does it save time, but it helps you avoid potentially getting more than what your budget allows for, while also making sure you get all the food you’ll need.”

      This program, along with many others, is part of MIT’s larger effort on fostering a more food-secure and sustainable campus for all students. Food Security Action Team members, including students, staff, and campus partners, are striving to achieve this goal by ensuring that there continues to be a well-organized and coordinated action around food security that can be implemented effectively each year. For example, to make shopping at Daily Table even easier, MIT has made it a priority to ensure the store accepts TechCash.

      No MIT student should go hungry due to lack of money or resources, and no student should feel like they need to be “really hungry” to ask for help. MIT offers several other resources to help students find the nutrition and other support they need. In addition, the Office of Student Wellbeing launched their DoingWell website, which offers programs and resources to help students prioritize their well-being by practicing healthy habits and getting support when they need it.

      “In my own cost-analysis comparison of staple grocery items of all the local grocery stores, no other store comes close to being able to offer what Daily Table does for the prices it does. It’s really remarkable to learn and experience just how Daily Table is changing the food system,” says Holton. “Its model is one of the many ways that will continue to foster a more food-secure community where everyone — including MIT students — can access affordable, nutritious food.” More

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      in Environment

      Reducing food waste to increase access to affordable foods

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      About a third of the world’s food supply never gets eaten. That means the water, labor, energy, and fertilizer that went into growing, processing, and distributing the food is wasted.

      On the other end of the supply chain are cash-strapped consumers, who have been further distressed in recent years by factors like the Covid-19 pandemic and inflation.

      Spoiler Alert, a company founded by two MIT alumni, is helping companies bridge the gap between food waste and food insecurity with a platform connecting major food and beverage brands with discount grocers, retailers, and nonprofits. The platform helps brands discount or donate excess and short-dated inventory days, weeks, and months before it expires.

      “There is a tremendous amount of underutilized data that exists in the manufacturing and distribution space that results in good food going to waste,” says Ricky Ashenfelter MBA ’15, who co-founded the company with Emily Malina MBA ’15.

      Spoiler Alert helps brands manage distressed inventory data, create offers for potential buyers, and review and accept bids. The platform is designed to work with companies’ existing inventory and fulfillment systems, using automation and pricing intelligence to further streamline sales.

      “At a high level, we’re a waste-prevention software built for sales and supply-chain teams,” Ashenfelter says. “You can think of it as a private [business-to-business] eBay of sorts.”

      Spoiler Alert is working with global companies like Nestle, Kraft Heinz, and Danone, as well as discount grocers like the United Grocery Outlet and Misfits Market. Those brands are already using the platform to reduce food waste and get more food on people’s tables.

      “Project Drawdown [a nonprofit working on climate solutions] has identified food waste as the number one priority to address the global climate crisis, so these types of corporate initiatives can be really powerful from an environmental standpoint,” Ashenfelter says, noting the nonprofit estimates food waste accounts for 8 percent of global greenhouse gas emissions. “Contrast that with growing levels of food insecurity and folks not being able to access affordable nutrition, and you start to see how tackling supply-chain inefficiency can have a dramatic impact from both an environmental and a social lens. That’s what motivates us.”

      Untapped data for change

      Ashenfelter came to MIT’s Sloan School of Management after several years in sustainability software and management consulting within the retail and consumer products industries.

      “I was really attracted to transitioning into something much more entrepreneurial, and to leverage not only Sloan’s focus on entrepreneurship, but also the broader MIT ecosystem’s focus on technology, entrepreneurship, clean tech innovation, and other themes along that front,” he says.

      Ashenfelter met Malina at one of Sloan’s admitted students events in 2013, and the founders soon set out to use data to decrease food waste.

      “For us, the idea was clear: How do we better leverage data to manage excess and short-dated inventory?” Ashenfelter says. “How we go about that has evolved over the last six years, but it’s all rooted in solving an enormous climate problem, solving a major food insecurity problem, and from a capitalistic standpoint, helping businesses cut costs and generate revenue from otherwise wasted products.”

      The founders spent many hours in the Martin Trust Center for MIT Entrepreneurship with support from the Sloan Sustainability Initiative, and used Spoiler Alert as a case study in nearly every class they took, thinking through product development, sales, marketing, pricing, and more through their coursework.

      “We brought our idea into just about every action learning class that we could at Sloan and MIT,” Ashenfelter says.

      They also participated in the MIT $100K Entrepreneurship Competition and received support from the Venture Mentoring Service and the IDEAS Global Challenge program.

      Upon graduation, the founders initially began building a platform to facilitate donations of excess inventory, but soon learned big companies’ processes for discounting that inventory were also highly manual. Today, more than 90 percent of Spoiler Alert’s transaction volume is discounted, with the remainder donated.

      Different teams within an organization can upload excess inventory reports to Spoiler Alert’s system, eliminating the need to manually aggregate datasets and preparing what the industry refers to as “blowout lists” to sell. Spoiler Alert uses machine-learning-based tools to help both parties with pricing and negotiations to close deals more quickly.

      “Companies are taking pretty manual and slow approaches to deciding [what to do with excess inventory],” Ashenfelter says. “And when you have slow decision-making, you’re losing days or even weeks of shelf life on that product. That can be the difference between selling product versus donating, and donating versus dumping.”

      Once a deal has been made, Spoiler Alert automatically generates the forms and workflows needed by fulfillment teams to get the product out the door. The relationships companies build on the platform are also a major driver for cutting down waste.

      “We’re providing suppliers with the ability to control where their discounted and donated product ends up,” Ashenfelter says. “That’s really powerful because it allows these CPG brands to ensure that this product is, in many cases, getting to affordable nutrition outlets in underserved communities.”

      Ashenfelter says the majority of inventory goes to regional and national discount grocers, supplemented with extensive purchasing from local and nonprofit grocery chains.

      “Everything we do is oriented around helping sell as much product as possible to a reputable set of buyers at the most fair, equitable prices possible,” Ashenfelter says.

      Scaling for impact

      The pandemic has disrupted many aspects of the food supply chains. But Ashenfelter says it has also accelerated the adoption of digital solutions that can better manage such volatility.

      When Campbell began using Spoiler Alert’s system in 2019, for instance, it achieved a 36 percent increase in discount sales and a 27 percent increase in donations over the first five months.

      Ashenfelter says the results have proven that companies’ sustainability targets can go hand in hand with initiatives that boost their bottom lines. In fact, because Spoiler Alert focuses so much on the untapped revenue associated with food waste, many customers don’t even realize Spoiler Alert is a sustainability company until after they’ve signed on.

      “What’s neat about this program is that it becomes an incredibly powerful case study internally for how sustainability and operational outcomes aren’t in conflict and can drive both business results as well as overall environmental impact,” Ashenfelter says.

      Going forward, Spoiler Alert will continue building out algorithmic solutions that could further cut down on waste internationally and across a wider array of products.

      “At every step in our process, we’re collecting a tremendous amount of data in terms of what is and isn’t selling, at what price point, to which buyers, out of which geographies, and with how much remaining shelf life,” Ashenfelter explains. “We are only starting to scratch the surface in terms of bringing our recommendations engine to life for our suppliers and buyers. Ultimately our goal is to power the waste-free economy, and rooted in that is making better decisions faster, in collaboration with a growing ecosystem of supply chain partners, and with as little manual intervention as possible.” More

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      in Security

      Meet the 2021-22 Accenture Fellows

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      Launched in October of 2020, the MIT and Accenture Convergence Initiative for Industry and Technology underscores the ways in which industry and technology come together to spur innovation. The five-year initiative aims to achieve its mission through research, education, and fellowships. To that end, Accenture has once again awarded five annual fellowships to MIT graduate students working on research in industry and technology convergence who are underrepresented, including by race, ethnicity, and gender.

      This year’s Accenture Fellows work across disciplines including robotics, manufacturing, artificial intelligence, and biomedicine. Their research covers a wide array of subjects, including: advancing manufacturing through computational design, with the potential to benefit global vaccine production; designing low-energy robotics for both consumer electronics and the aerospace industry; developing robotics and machine learning systems that may aid the elderly in their homes; and creating ingestible biomedical devices that can help gather medical data from inside a patient’s body.

      Student nominations from each unit within the School of Engineering, as well as from the four other MIT schools and the MIT Schwarzman College of Computing, were invited as part of the application process. Five exceptional students were selected as fellows in the initiative’s second year.

      Xinming (Lily) Liu is a PhD student in operations research at MIT Sloan School of Management. Her work is focused on behavioral and data-driven operations for social good, incorporating human behaviors into traditional optimization models, designing incentives, and analyzing real-world data. Her current research looks at the convergence of social media, digital platforms, and agriculture, with particular attention to expanding technological equity and economic opportunity in developing countries. Liu earned her BS from Cornell University, with a double major in operations research and computer science.

      Caris Moses is a PhD student in electrical engineering and computer science specializing inartificial intelligence. Moses’ research focuses on using machine learning, optimization, and electromechanical engineering to build robotics systems that are robust, flexible, intelligent, and can learn on the job. The technology she is developing holds promise for industries including flexible, small-batch manufacturing; robots to assist the elderly in their households; and warehouse management and fulfillment. Moses earned her BS in mechanical engineering from Cornell University and her MS in computer science from Northeastern University.

      Sergio Rodriguez Aponte is a PhD student in biological engineering. He is working on the convergence of computational design and manufacturing practices, which have the potential to impact industries such as biopharmaceuticals, food, and wellness/nutrition. His current research aims to develop strategies for applying computational tools, such as multiscale modeling and machine learning, to the design and production of manufacturable and accessible vaccine candidates that could eventually be available globally. Rodriguez Aponte earned his BS in industrial biotechnology from the University of Puerto Rico at Mayaguez.

      Soumya Sudhakar SM ’20 is a PhD student in aeronautics and astronautics. Her work is focused on theco-design of new algorithms and integrated circuits for autonomous low-energy robotics that could have novel applications in aerospace and consumer electronics. Her contributions bring together the emerging robotics industry, integrated circuits industry, aerospace industry, and consumer electronics industry. Sudhakar earned her BSE in mechanical and aerospace engineering from Princeton University and her MS in aeronautics and astronautics from MIT.

      So-Yoon Yang is a PhD student in electrical engineering and computer science. Her work on the development of low-power, wireless, ingestible biomedical devices for health care is at the intersection of the medical device, integrated circuit, artificial intelligence, and pharmaceutical fields. Currently, the majority of wireless biomedical devices can only provide a limited range of medical data measured from outside the body. Ingestible devices hold promise for the next generation of personal health care because they do not require surgical implantation, can be useful for detecting physiological and pathophysiological signals, and can also function as therapeutic alternatives when treatment cannot be done externally. Yang earned her BS in electrical and computer engineering from Seoul National University in South Korea and her MS in electrical engineering from Caltech. More

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      in Environment

      SMART researchers develop method for early detection of bacterial infection in crops

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      Researchers from the Disruptive and Sustainable Technologies for Agricultural Precision (DiSTAP) Interdisciplinary Research Group (IRG) ofSingapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, and their local collaborators from Temasek Life Sciences Laboratory (TLL), have developed a rapid Raman spectroscopy-based method for detecting and quantifying early bacterial infection in crops. The Raman spectral biomarkers and diagnostic algorithm enable the noninvasive and early diagnosis of bacterial infections in crop plants, which can be critical for the progress of plant disease management and agricultural productivity.

      Due to the increasing demand for global food supply and security, there is a growing need to improve agricultural production systems and increase crop productivity. Globally, bacterial pathogen infection in crop plants is one of the major contributors to agricultural yield losses. Climate change also adds to the problem by accelerating the spread of plant diseases. Hence, developing methods for rapid and early detection of pathogen-infected crops is important to improve plant disease management and reduce crop loss.

      The breakthrough by SMART and TLL researchers offers a faster and more accurate method to detect bacterial infection in crop plants at an earlier stage, as compared to existing techniques. The new results appear in a paper titled “Rapid detection and quantification of plant innate immunity response using Raman spectroscopy” published in the journal Frontiers in Plant Science.

      “The early detection of pathogen-infected crop plants is a significant step to improve plant disease management,” says Chua Nam Hai, DiSTAP co-lead principal investigator, professor, TLL deputy chair, and co-corresponding author. “It will allow the fast and selective removal of pathogen load and curb the further spread of disease to other neighboring crops.”

      Traditionally, plant disease diagnosis involves a simple visual inspection of plants for disease symptoms and severity. “Visual inspection methods are often ineffective, as disease symptoms usually manifest only at relatively later stages of infection, when the pathogen load is already high and reparative measures are limited. Hence, new methods are required for rapid and early detection of bacterial infection. The idea would be akin to having medical tests to identify human diseases at an early stage, instead of waiting for visual symptoms to show, so that early intervention or treatment can be applied,” says MIT Professor Rajeev Ram, who is a DiSTAP principal investigator and co-corresponding author on the paper.

      While existing techniques, such as current molecular detection methods, can detect bacterial infection in plants, they are often limited in their use. Molecular detection methods largely depend on the availability of pathogen-specific gene sequences or antibodies to identify bacterial infection in crops; the implementation is also time-consuming and nonadaptable for on-site field application due to the high cost and bulky equipment required, making it impractical for use in agricultural farms.

      “At DiSTAP, we have developed a quantitative Raman spectroscopy-based algorithm that can help farmers to identify bacterial infection rapidly. The developed diagnostic algorithm makes use of Raman spectral biomarkers and can be easily implemented in cloud-based computing and prediction platforms. It is more effective than existing techniques as it enables accurate identification and early detection of bacterial infection, both of which are crucial to saving crop plants that would otherwise be destroyed,” explains Gajendra Pratap Singh, scientific director and principal investigator at DiSTAP and co-lead author.

      A portable Raman system can be used on farms and provides farmers with an accurate and simple yes-or-no response when used to test for the presence of bacterial infections in crops. The development of this rapid and noninvasive method could improve plant disease management and have a transformative impact on agricultural farms by efficiently reducing agricultural yield loss and increasing productivity.

      “Using the diagnostic algorithm method, we experimented on several edible plants such as choy sum,” says DiSTAP and TLL principal investigator and co-corresponding author Rajani Sarojam. “The results showed that the Raman spectroscopy-based method can swiftly detect and quantify innate immunity response in plants infected with bacterial pathogens. We believe that this technology will be beneficial for agricultural farms to increase their productivity by reducing their yield loss due to plant diseases.”

      The researchers are currently working on the development of high-throughput, custom-made portable or hand-held Raman spectrometers that will allow Raman spectral analysis to be quickly and easily performed on field-grown crops.

      SMART and TLL developed and discovered the diagnostic algorithm and Raman spectral biomarkers. TLL also confirmed and validated the detection method through mutant plants. The research is carried out by SMART and supported by the National Research Foundation of Singapore under its Campus for Research Excellence And Technological Enterprise (CREATE) program.

      SMART was established by MIT and the NRF in 2007. The first entity in CREATE developed by NRF, SMART serves as an intellectual and innovation hub for research interactions between MIT and Singapore, undertaking cutting-edge research projects in areas of interest to both Singapore and MIT. SMART currently comprises an Innovation Center and five IRGs: Antimicrobial Resistance, Critical Analytics for Manufacturing Personalized-Medicine, DiSTAP, Future Urban Mobility, and Low Energy Electronic Systems. SMART research is funded by the NRF under the CREATE program.

      Led by Professor Michael Strano of MIT and Professor Chua Nam Hai of Temasek Lifesciences Laboratory, the DiSTAP program addresses deep problems in food production in Singapore and the world by developing a suite of impactful and novel analytical, genetic, and biomaterial technologies. The goal is to fundamentally change how plant biosynthetic pathways are discovered, monitored, engineered, and ultimately translated to meet the global demand for food and nutrients. Scientists from MIT, TTL, Nanyang Technological University, and National University of Singapore are collaboratively developing new tools for the continuous measurement of important plant metabolites and hormones for novel discovery, deeper understanding and control of plant biosynthetic pathways in ways not yet possible, especially in the context of green leafy vegetables; leveraging these new techniques to engineer plants with highly desirable properties for global food security, including high-yield density production, and drought and pathogen resistance; and applying these technologies to improve urban farming. More

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      in Energy

      At UN climate change conference, trying to “keep 1.5 alive”

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      After a one-year delay caused by the Covid-19 pandemic, negotiators from nearly 200 countries met this month in Glasgow, Scotland, at COP26, the United Nations climate change conference, to hammer out a new global agreement to reduce greenhouse gas emissions and prepare for climate impacts. A delegation of approximately 20 faculty, staff, and students from MIT was on hand to observe the negotiations, share and conduct research, and launch new initiatives.

      On Saturday, Nov. 13, following two weeks of negotiations in the cavernous Scottish Events Campus, countries’ representatives agreed to the Glasgow Climate Pact. The pact reaffirms the goal of the 2015 Paris Agreement “to pursue efforts” to limit the global average temperature increase to 1.5 degrees Celsius above preindustrial levels, and recognizes that achieving this goal requires “reducing global carbon dioxide emissions by 45 percent by 2030 relative to the 2010 level and to net zero around mid-century.”

      “On issues like the need to reach net-zero emissions, reduce methane pollution, move beyond coal power, and tighten carbon accounting rules, the Glasgow pact represents some meaningful progress, but we still have so much work to do,” says Maria Zuber, MIT’s vice president for research, who led the Institute’s delegation to COP26. “Glasgow showed, once again, what a wicked complex problem climate change is, technically, economically, and politically. But it also underscored the determination of a global community of people committed to addressing it.”

      An “ambition gap”

      Both within the conference venue and at protests that spilled through the streets of Glasgow, one rallying cry was “keep 1.5 alive.” Alok Sharma, who was appointed by the UK government to preside over COP26, said in announcing the Glasgow pact: “We can now say with credibility that we have kept 1.5 degrees alive. But, its pulse is weak and it will only survive if we keep our promises and translate commitments into rapid action.”

      In remarks delivered during the first week of the conference, Sergey Paltsev, deputy director of MIT’s Joint Program on the Science and Policy of Global Change, presented findings from the latest MIT Global Change Outlook, which showed a wide gap between countries’ nationally determined contributions (NDCs) — the UN’s term for greenhouse gas emissions reduction pledges — and the reductions needed to put the world on track to meet the goals of the Paris Agreement and, now, the Glasgow pact.

      Pointing to this ambition gap, Paltsev called on all countries to do more, faster, to cut emissions. “We could dramatically reduce overall climate risk through more ambitious policy measures and investments,” says Paltsev. “We need to employ an integrated approach of moving to zero emissions in energy and industry, together with sustainable development and nature-based solutions, simultaneously improving human well-being and providing biodiversity benefits.”

      Finalizing the Paris rulebook

      A key outcome of COP26 (COP stands for “conference of the parties” to the UN Framework Convention on Climate Change, held for the 26th time) was the development of a set of rules to implement Article 6 of the Paris Agreement, which provides a mechanism for countries to receive credit for emissions reductions that they finance outside their borders, and to cooperate by buying and selling emissions reductions on international carbon markets.

      An agreement on this part of the Paris “rulebook” had eluded negotiators in the years since the Paris climate conference, in part because negotiators were concerned about how to prevent double-counting, wherein both buyers and sellers would claim credit for the emissions reductions.

      Michael Mehling, the deputy director of MIT’s Center for Energy and Environmental Policy Research (CEEPR) and an expert on international carbon markets, drew on a recent CEEPR working paper to describe critical negotiation issues under Article 6 during an event at the conference on Nov. 10 with climate negotiators and private sector representatives.

      He cited research that finds that Article 6, by leveraging the cost-efficiency of global carbon markets, could cut in half the cost that countries would incur to achieve their nationally determined contributions. “Which, seen from another angle, means you could double the ambition of these NDCs at no additional cost,” Mehling noted in his talk, adding that, given the persistent ambition gap, “any such opportunity is bitterly needed.”

      Andreas Haupt, a graduate student in the Institute for Data, Systems, and Society, joined MIT’s COP26 delegation to follow Article 6 negotiations. Haupt described the final days of negotiations over Article 6 as a “roller coaster.” Once negotiators reached an agreement, he says, “I felt relieved, but also unsure how strong of an effect the new rules, with all their weaknesses, will have. I am curious and hopeful regarding what will happen in the next year until the next large-scale negotiations in 2022.”

      Nature-based climate solutions

      World leaders also announced new agreements on the sidelines of the formal UN negotiations. One such agreement, a declaration on forests signed by more than 100 countries, commits to “working collectively to halt and reverse forest loss and land degradation by 2030.”

      A team from MIT’s Environmental Solutions Initiative (ESI), which has been working with policymakers and other stakeholders on strategies to protect tropical forests and advance other nature-based climate solutions in Latin America, was at COP26 to discuss their work and make plans for expanding it.

      Marcela Angel, a research associate at ESI, moderated a panel discussion featuring John Fernández, professor of architecture and ESI’s director, focused on protecting and enhancing natural carbon sinks, particularly tropical forests such as the Amazon that are at risk of deforestation, forest degradation, and biodiversity loss.

      “Deforestation and associated land use change remain one of the main sources of greenhouse gas emissions in most Amazonian countries, such as Brazil, Peru, and Colombia,” says Angel. “Our aim is to support these countries, whose nationally determined contributions depend on the effectiveness of policies to prevent deforestation and promote conservation, with an approach based on the integration of targeted technology breakthroughs, deep community engagement, and innovative bioeconomic opportunities for local communities that depend on forests for their livelihoods.”

      Energy access and renewable energy

      Worldwide, an estimated 800 million people lack access to electricity, and billions more have only limited or erratic electrical service. Providing universal access to energy is one of the UN’s sustainable development goals, creating a dual challenge: how to boost energy access without driving up greenhouse gas emissions.

      Rob Stoner, deputy director for science and technology of the MIT Energy Initiative (MITEI), and Ignacio Pérez-Arriaga, a visiting professor at the Sloan School of Management, attended COP26 to share their work as members of the Global Commission to End Energy Poverty, a collaboration between MITEI and the Rockefeller Foundation. It brings together global energy leaders from industry, the development finance community, academia, and civil society to identify ways to overcome barriers to investment in the energy sectors of countries with low energy access.

      The commission’s work helped to motivate the formation, announced at COP26 on Nov. 2, of the Global Energy Alliance for People and Planet, a multibillion-dollar commitment by the Rockefeller and IKEA foundations and Bezos Earth Fund to support access to renewable energy around the world.

      Another MITEI member of the COP26 delegation, Martha Broad, the initiative’s executive director, spoke about MIT research to inform the U.S. goal of scaling offshore wind energy capacity from approximately 30 megawatts today to 30 gigawatts by 2030, including significant new capacity off the coast of New England.

      Broad described research, funded by MITEI member companies, on a coating that can be applied to the blades of wind turbines to prevent icing that would require the turbines’ shutdown; the use of machine learning to inform preventative turbine maintenance; and methodologies for incorporating the effects of climate change into projections of future wind conditions to guide wind farm siting decisions today. She also spoke broadly about the need for public and private support to scale promising innovations.

      “Clearly, both the public sector and the private sector have a role to play in getting these technologies to the point where we can use them in New England, and also where we can deploy them affordably for the developing world,” Broad said at an event sponsored by America Is All In, a coalition of nonprofit and business organizations.

      Food and climate alliance

      Food systems around the world are increasingly at risk from the impacts of climate change. At the same time, these systems, which include all activities from food production to consumption and food waste, are responsible for about one-third of the human-caused greenhouse gas emissions warming the planet.

      At COP26, MIT’s Abdul Latif Jameel Water and Food Systems Lab announced the launch of a new alliance to drive research-based innovation that will make food systems more resilient and sustainable, called the Food and Climate Systems Transformation (FACT) Alliance. With 16 member institutions, the FACT Alliance will better connect researchers to farmers, food businesses, policymakers, and other food systems stakeholders around the world.

      Looking ahead

      By the end of 2022, the Glasgow pact asks countries to revisit their nationally determined contributions and strengthen them to bring them in line with the temperature goals of the Paris Agreement. The pact also “notes with deep regret” the failure of wealthier countries to collectively provide poorer countries $100 billion per year in climate financing that they pledged in 2009 to begin in 2020.

      These and other issues will be on the agenda for COP27, to be held in Sharm El-Sheikh, Egypt, next year.

      “Limiting warming to 1.5 degrees is broadly accepted as a critical goal to avoiding worsening climate consequences, but it’s clear that current national commitments will not get us there,” says ESI’s Fernández. “We will need stronger emissions reductions pledges, especially from the largest greenhouse gas emitters. At the same time, expanding creativity, innovation, and determination from every sector of society, including research universities, to get on with real-world solutions is essential. At Glasgow, MIT was front and center in energy systems, cities, nature-based solutions, and more. The year 2030 is right around the corner so we can’t afford to let up for one minute.” More

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      J-WAFS launches Food and Climate Systems Transformation Alliance

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      Food systems around the world are increasingly at risk from the impacts of climate change. At the same time, these systems, which include all activities from food production to consumption and food waste, are responsible for about one-third of the human-caused greenhouse gas emissions warming the planet. 

      To drive research-based innovation that will make food systems more resilient and sustainable, MIT’s Abdul Latif Jameel Water and Food Systems Lab (J-WAFS) announced the launch of a new initiative at an event during the UN Climate Change Conference in Glasgow, Scotland, last week. The initiative, called the Food and Climate Systems Transformation (FACT) Alliance, will better connect researchers to farmers, food businesses, policymakers, and other food systems stakeholders around the world. 

      “Time is not on our side,” says Greg Sixt, the director of the FACT Alliance and research manager for food and climate systems at J-WAFS. “To date, the research community hasn’t delivered actionable solutions quickly enough or in the policy-relevant form needed if time-critical changes are to be made to our food systems. The FACT Alliance aims to change this.”

      Why, in fact, do our food systems need transformation?

      At COP26 (which stands for “conference of the parties” to the UN Framework Convention on Climate Change, being held for the 26th time this year), a number of countries have pledged to end deforestation, reduce methane emissions, and cease public financing of coal power. In his keynote address at the FACT Alliance event, Professor Pete Smith of the University of Aberdeen, an alliance member institution, noted that food and agriculture also need to be addressed because “there’s an interaction between climate change and the food system.” 

      The UN Intergovernmental Panel on Climate Change warns that a two-degree Celsius increase in average global temperature over preindustrial levels could trigger a worldwide food crisis, and emissions from food systems alone could push us past the two-degree mark even if energy-related emissions could be zeroed out. 

      Smith said dramatic and rapid transformations are needed to deliver safe, nutritious food for all, with reduced environmental impact and increased resilience to climate change. With a global network of leading research institutions and collaborating stakeholder organizations, the FACT Alliance aims to facilitate new, solutions-oriented research for addressing the most challenging aspects of food systems in the era of climate change. 

      How the FACT Alliance works

      Central to the work of the FACT Alliance is the development of new methodologies for aligning data across scales and food systems components, improving data access, integrating research across the diverse disciplines that address aspects of food systems, making stakeholders partners in the research process, and assessing impact in the context of complex and interconnected food and climate systems. 

      The FACT Alliance will conduct what’s known as “convergence research,” which meets complex problems with approaches that embody deep integration across disciplines. This kind of research calls for close association with the stakeholders who both make decisions and are directly affected by how food systems work, be they farmers, extension services (i.e., agricultural advisories), policymakers, international aid organizations, consumers, or others. By inviting stakeholders and collaborators to be part of the research process, the FACT Alliance allows for engagement at the scale, geography, and scope that is most relevant to the needs of each, integrating global and local teams to achieve better outcomes. 

      “Doing research in isolation of all the stakeholders and in isolation of the goals that we want to achieve will not deliver the transformation that we need,” said Smith. “The problem is too big for us to solve in isolation, and we need broad alliances to tackle the issue, and that’s why we developed the FACT Alliance.” 

      Members and collaborators

      Led by MIT’s J-WAFS, the FACT Alliance is currently made up of 16 core members and an associated network of collaborating stakeholder organizations. 

      “As the central convener of MIT research on food systems, J-WAFS catalyzes collaboration across disciplines,” says Maria Zuber, vice president for research at MIT. “Now, by bringing together a world-class group of research institutions and stakeholders from key sectors, the FACT Alliance aims to advance research that will help alleviate climate impacts on food systems and mitigate food system impacts on climate.”

      J-WAFS co-hosted the COP26 event “Bridging the Science-Policy Gap for Impactful, Demand-Driven Food Systems Innovation” with Columbia University, the American University of Beirut, and the CGIAR research program Climate Change, Agriculture and Food Security (CCAFS). The event featured a panel discussion with several FACT Alliance members and the UK Foreign, Commonwealth and Development Office (FCDO). More