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      in Environment

      Study finds natural sources of air pollution exceed air quality guidelines in many regions

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      Alongside climate change, air pollution is one of the biggest environmental threats to human health. Tiny particles known as particulate matter or PM2.5 (named for their diameter of just 2.5 micrometers or less) are a particularly hazardous type of pollutant. These particles are produced from a variety of sources, including wildfires and the burning of fossil fuels, and can enter our bloodstream, travel deep into our lungs, and cause respiratory and cardiovascular damage. Exposure to particulate matter is responsible for millions of premature deaths globally every year.

      In response to the increasing body of evidence on the detrimental effects of PM2.5, the World Health Organization (WHO) recently updated its air quality guidelines, lowering its recommended annual PM2.5 exposure guideline by 50 percent, from 10 micrograms per meter cubed (μm3) to 5 μm3. These updated guidelines signify an aggressive attempt to promote the regulation and reduction of anthropogenic emissions in order to improve global air quality.

      A new study by researchers in the MIT Department of Civil and Environmental Engineering explores if the updated air quality guideline of 5 μm3 is realistically attainable across different regions of the world, particularly if anthropogenic emissions are aggressively reduced. 

      The first question the researchers wanted to investigate was to what degree moving to a no-fossil-fuel future would help different regions meet this new air quality guideline.

      “The answer we found is that eliminating fossil-fuel emissions would improve air quality around the world, but while this would help some regions come into compliance with the WHO guidelines, for many other regions high contributions from natural sources would impede their ability to meet that target,” says senior author Colette Heald, the Germeshausen Professor in the MIT departments of Civil and Environmental Engineering, and Earth, Atmospheric and Planetary Sciences. 

      The study by Heald, Professor Jesse Kroll, and graduate students Sidhant Pai and Therese Carter, published June 6 in the journal Environmental Science and Technology Letters, finds that over 90 percent of the global population is currently exposed to average annual concentrations that are higher than the recommended guideline. The authors go on to demonstrate that over 50 percent of the world’s population would still be exposed to PM2.5 concentrations that exceed the new air quality guidelines, even in the absence of all anthropogenic emissions.

      This is due to the large natural sources of particulate matter — dust, sea salt, and organics from vegetation — that still exist in the atmosphere when anthropogenic emissions are removed from the air. 

      “If you live in parts of India or northern Africa that are exposed to large amounts of fine dust, it can be challenging to reduce PM2.5 exposures below the new guideline,” says Sidhant Pai, co-lead author and graduate student. “This study challenges us to rethink the value of different emissions abatement controls across different regions and suggests the need for a new generation of air quality metrics that can enable targeted decision-making.”

      The researchers conducted a series of model simulations to explore the viability of achieving the updated PM2.5 guidelines worldwide under different emissions reduction scenarios, using 2019 as a representative baseline year. 

      Their model simulations used a suite of different anthropogenic sources that could be turned on and off to study the contribution of a particular source. For instance, the researchers conducted a simulation that turned off all human-based emissions in order to determine the amount of PM2.5 pollution that could be attributed to natural and fire sources. By analyzing the chemical composition of the PM2.5 aerosol in the atmosphere (e.g., dust, sulfate, and black carbon), the researchers were also able to get a more accurate understanding of the most important PM2.5 sources in a particular region. For example, elevated PM2.5 concentrations in the Amazon were shown to predominantly consist of carbon-containing aerosols from sources like deforestation fires. Conversely, nitrogen-containing aerosols were prominent in Northern Europe, with large contributions from vehicles and fertilizer usage. The two regions would thus require very different policies and methods to improve their air quality. 

      “Analyzing particulate pollution across individual chemical species allows for mitigation and adaptation decisions that are specific to the region, as opposed to a one-size-fits-all approach, which can be challenging to execute without an understanding of the underlying importance of different sources,” says Pai. 

      When the WHO air quality guidelines were last updated in 2005, they had a significant impact on environmental policies. Scientists could look at an area that was not in compliance and suggest high-level solutions to improve the region’s air quality. But as the guidelines have tightened, globally-applicable solutions to manage and improve air quality are no longer as evident. 

      “Another benefit of speciating is that some of the particles have different toxicity properties that are correlated to health outcomes,” says Therese Carter, co-lead author and graduate student. “It’s an important area of research that this work can help motivate. Being able to separate out that piece of the puzzle can provide epidemiologists with more insights on the different toxicity levels and the impact of specific particles on human health.”

      The authors view these new findings as an opportunity to expand and iterate on the current guidelines.  

      “Routine and global measurements of the chemical composition of PM2.5 would give policymakers information on what interventions would most effectively improve air quality in any given location,” says Jesse Kroll, a professor in the MIT departments of Civil and Environmental Engineering and Chemical Engineering. “But it would also provide us with new insights into how different chemical species in PM2.5 affect human health.”

      “I hope that as we learn more about the health impacts of these different particles, our work and that of the broader atmospheric chemistry community can help inform strategies to reduce the pollutants that are most harmful to human health,” adds Heald. More

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      in Security

      Using soap to remove micropollutants from water

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      Imagine millions of soapy sponges the size of human cells that can clean water by soaking up contaminants. This simplistic model is used to describe technology that MIT chemical engineers have recently developed to remove micropollutants from water — a concerning, worldwide problem.

      Patrick S. Doyle, the Robert T. Haslam Professor of Chemical Engineering, PhD student Devashish Pratap Gokhale, and undergraduate Ian Chen recently published their research on micropollutant removal in the journal ACS Applied Polymer Materials. The work is funded by MIT’s Abdul Latif Jameel Water and Food Systems Lab (J-WAFS).

      In spite of their low concentrations (about 0.01–100 micrograms per liter), micropollutants can be hazardous to the ecosystem and to human health. They come from a variety of sources and have been detected in almost all bodies of water, says Gokhale. Pharmaceuticals passing through people and animals, for example, can end up as micropollutants in the water supply. Others, like endocrine disruptor bisphenol A (BPA), can leach from plastics during industrial manufacturing. Pesticides, dyes, petrochemicals, and per-and polyfluoroalkyl substances, more commonly known as PFAS, are also examples of micropollutants, as are some heavy metals like lead and arsenic. These are just some of the kinds of micropollutants, all of which can be toxic to humans and animals over time, potentially causing cancer, organ damage, developmental defects, or other adverse effects.

      Micropollutants are numerous but since their collective mass is small, they are difficult to remove from water. Currently, the most common practice for removing micropollutants from water is activated carbon adsorption. In this process, water passes through a carbon filter, removing only 30 percent of micropollutants. Activated carbon requires high temperatures to produce and regenerate, requiring specialized equipment and consuming large amounts of energy. Reverse osmosis can also be used to remove micropollutants from water; however, “it doesn’t lead to good elimination of this class of molecules, because of both their concentration and their molecular structure,” explains Doyle.

      Inspired by soap

      When devising their solution for how to remove micropollutants from water, the MIT researchers were inspired by a common household cleaning supply — soap. Soap cleans everything from our hands and bodies to dirty dishes to clothes, so perhaps the chemistry of soap could also be applied to sanitizing water. Soap has molecules called surfactants which have both hydrophobic (water-hating) and hydrophilic (water-loving) components. When water comes in contact with soap, the hydrophobic parts of the surfactant stick together, assembling into spherical structures called micelles with the hydrophobic portions of the molecules in the interior. The hydrophobic micelle cores trap and help carry away oily substances like dirt. 

      Doyle’s lab synthesized micelle-laden hydrogel particles to essentially cleanse water. Gokhale explains that they used microfluidics which “involve processing fluids on very small, micron-like scales” to generate uniform polymeric hydrogel particles continuously and reproducibly. These hydrogels, which are porous and absorbent, incorporate a surfactant, a photoinitiator (a molecule that creates reactive species), and a cross-linking agent known as PEGDA. The surfactant assembles into micelles that are chemically bonded to the hydrogel using ultraviolet light. When water flows through this micro-particle system, micropollutants latch onto the micelles and separate from the water. The physical interaction used in the system is strong enough to pull micropollutants from water, but weak enough that the hydrogel particles can be separated from the micropollutants, restabilized, and reused. Lab testing shows that both the speed and extent of pollutant removal increase when the amount of surfactant incorporated into the hydrogels is increased.

      “We’ve shown that in terms of rate of pullout, which is what really matters when you scale this up for industrial use, that with our initial format, we can already outperform the activated carbon,” says Doyle. “We can actually regenerate these particles very easily at room temperature. Nearly 10 regeneration cycles with minimal change in performance,” he adds.

      Regeneration of the particles occurs by soaking the micelles in 90 percent ethanol, whereby “all the pollutants just come out of the particles and back into the ethanol” says Gokhale. Ethanol is biosafe at low concentrations, inexpensive, and combustible, allowing for safe and economically feasible disposal. The recycling of the hydrogel particles makes this technology sustainable, which is a large advantage over activated carbon. The hydrogels can also be tuned to any hydrophobic micropollutant, making this system a novel, flexible approach to water purification.

      Scaling up

      The team experimented in the lab using 2-naphthol, a micropollutant that is an organic pollutant of concern and known to be difficult to remove by using conventional water filtration methods. They hope to continue testing with real water samples. 

      “Right now, we spike one micropollutant into pure lab water. We’d like to get water samples from the natural environment, that we can study and look at experimentally,” says Doyle. 

      By using microfluidics to increase particle production, Doyle and his lab hope to make household-scale filters to be tested with real wastewater. They then anticipate scaling up to municipal water treatment or even industrial wastewater treatment. 

      The lab recently filed an international patent application for their hydrogel technology that uses immobilized micelles. They plan to continue this work by experimenting with different kinds of hydrogels for the removal of heavy metal contaminants like lead from water. 

      Societal impacts

      Funded by a 2019 J-WAFS seed grant that is currently ongoing, this research has the potential to improve the speed, precision, efficiency, and environmental sustainability of water purification systems across the world. 

      “I always wanted to do work which had a social impact, and I was also always interested in water, because I think it’s really cool,” says Gokhale. He notes, “it’s really interesting how water sort of fits into different kinds of fields … we have to consider the cultures of peoples, how we’re going to use this, and then just the equity of these water processes.” Originally from India, Gokhale says he’s seen places that have barely any water at all and others that have floods year after year. “There’s a lot of interesting work to be done, and I think it’s work in this area that’s really going to impact a lot of people’s lives in years to come,” Gokhale says.

      Doyle adds, “water is the most important thing, perhaps for the next decades to come, so it’s very fulfilling to work on something that is so important to the whole world.” More

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      in Environment

      Progress toward a sustainable campus food system

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      As part of MIT’s updated climate action plan, known as “Fast Forward,” Institute leadership committed to establishing a set of quantitative goals in 2022 related to food, water, and waste systems that advance MIT’s commitment to climate. Moving beyond the impact of campus energy systems, these newly proposed goals take a holistic view of the drivers of climate change and set the stage for new frontiers of collaborative climate work. “With the release of ‘Fast Forward,’ the MIT Office of Sustainability is setting out to partner with campus groups to study and quantify the climate impact of our campus food, while deeply considering the social, cultural, economic, and health aspects of a sustainable food system,” explains Susy Jones, senior sustainability project manager. 

      While “Fast Forward” is MIT’s first climate action plan to integrate the campus food system, the Division of Student Life (DSL) has long worked with dining vendors, MIT’s Office of Sustainability (MITOS), and other campus partners to advance a more sustainable, affordable, and equitable food system. Initiatives have ranged from increasing access to low-cost groceries on and around campus to sourcing sustainable coffee for campus cafes.

      Even with the complexities of operating during the pandemic, efforts in this area accelerated with the launch of new partnerships, support for local food industries, and even a food-startup incubator in the Stratton Student Center (Building W20). “Despite challenges posed by the pandemic, MIT Dining has been focused on positive change — driven in part by student input, alterations to the food landscape, and our ongoing goal to support a more sustainable and equitable campus food system,” says Mark Hayes, director of MIT Dining.

      New vendors on campus focus on healthy food systems

      For many, a fresh cup of coffee is a daily ritual. At MIT, that cup of coffee also offers an opportunity to make a more sustainable choice at the Forbes Family Café in the Stata Center (Building 32). The cafe now brews coffee by Dean’s Beans, a local roaster whose mission is to “prove that a for-profit business could create meaningful change through ethical business practices rooted in respect for the earth, the farmer, our co-workers, and the consumer.” The choice of Dean’s Beans — a certified B Corporation located in Orange, Massachusetts — as the new vendor in this space helps advance MIT’s commitment to sustainability. Businesses that achieve this certification meet rigorous social and environmental goals. “With choices like this, we’re taking big issues down to the campus level,” says Hayes. Dean’s Beans focuses on long-term producer relationships, organic shade-grown and bird-friendly coffee, a solar-powered roasting facility, and people-centered development programs. These practices contribute to healthier environments and habitats — benefiting farmers, soils, birds, pollinators, and more.

      Another innovative new food concept for the MIT community can be found down the street in the Stratton Student Center. The Launchpad, a nonprofit food business incubator created in partnership with CommonWealth Kitchen (CWK), debuted this fall in the second-floor Lobdell Food Court. It offers the MIT community more variety and healthy food options while also “advancing CWK’s and MIT’s mutual goal to support diverse, local start-up food businesses and to create a more just, equitable, and sustainable food economy,” according to DSL. Work on the Launchpad began in 2018, bringing together the Student Center Dining Concepts Working Group, comprising students from the Undergraduate Association, Graduate Student Council, DormCon, house dining chairs, and other students interested in dining and dining staff from the MITOS and DSL. Their goal was to re-envision dining options available in Lobdell to support local, diverse, and sustainable menus. “We’ve been nurturing a partnership with CommonWealth Kitchen for years and are excited to partner with them on a project that re-imagines the relationship between campus and local food systems,” says Jones. “And, of course, the vegetarian arepas are a highlight,” she adds.

      Local partnerships for sustainability

      The impacts of Covid-19 on local food businesses quickly came into focus in early 2020. For the New England fishing industry, this impact was acute — with restaurant closures, event cancellations, and disruptions in the global supply chain, fisheries suddenly found a dearth of markets for their catch, undermining their source of income. One way to address this confluence of challenges was for fisheries to expand into new markets where they may have had limited knowledge or experience.

      Enter MIT Sea Grant and MIT Dining. Supported in part by funding from the National Oceanic and Atmospheric Administration, MIT Sea Grant created the Covid-19 Rapid Response Program to develop new markets for local fisheries, including local food banks and direct sales to organizations including MIT. Though MIT Dining was stretched thin by the pandemic, the partnership offered a singular opportunity to support vital regional businesses and enhance menus in campus dining venues. “The stress level was unimaginable as more people were testing positive in the early days of the pandemic — it was the worst and most stressful time to do anything outside of what was completely necessary, and I get this phone call about chowder,” recalls Hayes. “Everyone is wearing two masks and standing six feet apart, but in about 15 seconds, I said to myself, ‘This is the exact time this needs to happen — in the middle of a pandemic when fishermen need support, families need support, people need support.’”

      Shortly after getting the call, Hayes and MIT Dining hosted a tasting event featuring “Small Boats, Big Taste Haddock Chowder,” developed through MIT Sea Grant’s work with the Cape Cod Commercial Fishermen’s Alliance, which helped independent fishermen stay on the water during Covid-19. The tasting event also offered students a break to stop by and sample the chowder, which later debuted and continues to be served at MIT dining halls. For Hayes, one success of the partnership was the agility it demonstrated. “We don’t know what the next crisis is going to be, but these experiences will make us stronger to handle the next moment when people need the food system to work,” he says.

      In addition to ready-made options for students, MIT Dining and partners have also been working to support students who prepare their own meals, collaborating with local businesses to provide students access to lower-cost and at-cost groceries and food products. The Food Security Action Team, convened by Senior Associate Dean for Student Support and Well-being David Randall and DSL Executive Director for Administration Peter Cummings, is focused on taking action, tracking, and updating the community on food security efforts. These efforts have included collaborating with the Daily Table, a new nonprofit community grocer in Central Square. The store now accepts TechCASH and recently worked with the committee to host an interactive food tour for students.

      Because food systems are so interdependent and partnerships are critical — on and off campus — Hayes says it’s important to continue to share and learn. “Sharing our stories is crucial because we can help strengthen networks of campuses, institutions, and businesses in New England to grow more sustainable food programs like these.” More

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      in Security

      MIT students explore food sustainability

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      As students approached the homestretch of the fall semester, many were focused on completing final projects and preparing for exams. During this time of year, some students may neglect their well-being to the point of skipping meals. To help alleviate end-of-term stress and to give students a delicious study break, the Food Security Action Team recently offered a group of first-year students the opportunity to join a food tour of Daily Table, a new grocer located in Cambridge’s Central Square.

      Seventeen students along with staff from Student Financial Services, Office of the First Year, and the Office of Sustainability led the group from the steps of 77 Massachusetts Avenue a few blocks down the street to Daily Table in Central Square. As part of participating in the program, students were given a $25 TechCash gift card to shop for grocery items during the trip. To make things even more fun, MIT staff created a recipe challenge to encourage students to work together on making their own variation of quesadillas.

      Healthy, affordable, sustainable

      At Daily Table, students were greeted by Celia Grant, director of community engagement and programs from Daily Table, who led them through a tour of the space and highlighted the history and model of the grocery store, as well as some of its unique features. Founded by former Trader Joe’s president Doug Rauch in 2015, Daily Table operates three retail stores in Dorchester, Roxbury, and Central Square, and a commissary kitchen in the Boston metro area. Two more stores are in the works: one in Mattapan and another in Salem. For added convenience, Daily Table also offers free grocery delivery within a two-mile radius of its three locations.

      The Daily Table’s ethos is that delicious and wholesome food should be available, accessible, and affordable for everyone. To achieve these goals, Daily Table provides a wide selection of fresh produce, nutritious grocery staples, and made-from-scratch prepared grab-n-go foods at affordable prices. “All of our products meet strict nutritional guidelines for sodium and sugar so that customers can make food choices based on their diets, not based on price,” says Grant.

      In addition to a large network of farmers, manufacturers, and distributors who supply food to their stores, Daily Table often recovers and rescues perfectly good food that would have otherwise been sent to landfills. Surplus food, packaging and/or label changes, and items with close expiration dates are often discarded by larger grocery stores in the supply chain. But Daily Table steps in to break this cycle of waste and sell these products to customers at a much lower cost. 

      The pandemic has uncovered how difficult it can be for individuals and families to budget for necessities like utilities, rent, and even food. Daily Table seeks to create a more sustainable future by providing access to more well-balanced, nutritious food. “Even before the pandemic, it was challenging for families on limited incomes to meet the nutrition needs of their families. Post-pandemic, this challenge has now encompassed even more households, even those that have never before been challenged in this way,” says Grant. “As winter moves through, and inflation increases, the need for more affordable food and nutrition will rise. Daily Table is prepared to help meet those needs, and more.” 

      Food resources at MIT

      Downstairs at the Daily Table Central Square store, MIT staff members led a discussion about the components of a sustainable food system at MIT and beyond, shared advice on how to budget for food, and offered tips on how to make grocery shopping or cooking fun with fellow classmates and peers. “Shopping at Daily Table provides an experiential case study in solving for multiple goals at once — from the environmental impacts of food waste to healthy eating to affordability — an important framework to consider when tackling climate challenges.” says Susy Jones, senior sustainability project manager in the MIT Office of Sustainability.

      The group also discussed budgeting expenses, including food. “By taking students to the grocery store and providing some small but meaningful tips, we provided them the opportunity to put their learning into practice!” says Erica Aguiar, associate director for financial education in Student Financial Services. “We saw students taking a closer look at prices and even coming together to share groceries.”

      MIT senior and DormCon Dining Chair Ashley Holton shared her grocery shopping strategies with the group, and how she utilizes resources available at MIT. “Having a plan before you enter the grocery store is really important,” says Holton. “Not only does it save time, but it helps you avoid potentially getting more than what your budget allows for, while also making sure you get all the food you’ll need.”

      This program, along with many others, is part of MIT’s larger effort on fostering a more food-secure and sustainable campus for all students. Food Security Action Team members, including students, staff, and campus partners, are striving to achieve this goal by ensuring that there continues to be a well-organized and coordinated action around food security that can be implemented effectively each year. For example, to make shopping at Daily Table even easier, MIT has made it a priority to ensure the store accepts TechCash.

      No MIT student should go hungry due to lack of money or resources, and no student should feel like they need to be “really hungry” to ask for help. MIT offers several other resources to help students find the nutrition and other support they need. In addition, the Office of Student Wellbeing launched their DoingWell website, which offers programs and resources to help students prioritize their well-being by practicing healthy habits and getting support when they need it.

      “In my own cost-analysis comparison of staple grocery items of all the local grocery stores, no other store comes close to being able to offer what Daily Table does for the prices it does. It’s really remarkable to learn and experience just how Daily Table is changing the food system,” says Holton. “Its model is one of the many ways that will continue to foster a more food-secure community where everyone — including MIT students — can access affordable, nutritious food.” More

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      in Environment

      3 Questions: Tolga Durak on building a safety culture at MIT

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      Environment, Health, and Safety Managing Director Tolga Durak heads a team working to build a strong safety culture at the Institute and to implement systems that lead to successful lab and makerspace operations. EHS is also pursuing new opportunities in the areas of safe and sustainable labs and applied makerspace research. 

      Durak holds a BS in mechanical engineering, a MS in industrial and systems engineering, and a PhD in building construction/environmental design and planning. He has over 20 years of experience in engineering and EHS in higher education, having served in such roles as authority having jurisdiction, responsible official, fire marshal, risk manager, radiation safety officer, laser safety officer, safety engineer, project manager, and emergency manager for government agencies, as well as universities with extensive health-care and research facilities.

      Q: What “words of wisdom” regarding lab/shop health and safety would you like to share with the research community? 

      A: EHS staff always strive to help maintain the safety and well-being of the MIT community. When it comes to lab/shop safety or any areas with hazards, first and foremost, we encourage wearing the appropriate personal protective equipment (PPE) when handling potentially hazardous materials. While PPE needs depend on the hazards and the space, common PPE includes safety glasses, lab coats, gloves, clothes that cover your skin, and closed-toe shoes. Shorts and open-toe shoes have no place in the lab/shop setting when hazardous materials are stored or used. Accidents will and do happen. The severity of injuries due to accidental exposures can be minimized when researchers are wearing PPE. Remember, there is only one you!   

      Overall, be aware of your surroundings, be knowledgeable about the hazards of the materials and equipment you are using, and be prepared for the unexpected. Ask yourself, “What’s the worst thing that can happen during this experiment or procedure?” Prepare by doing a thorough risk assessment, ask others who may be knowledgeable for their ideas and help, and standardize procedures where possible. Be prepared to respond appropriately when an emergency arises. 

      Safety in our classrooms, labs, and makerspaces is paramount and requires a collaborative effort. 

      Q: What are the established programs within EHS that students and researchers should be aware of, and what opportunities and challenges do you face trying to advance a healthy safety culture at MIT? 

      A: The EHS program staff in Biosafety, Industrial Hygiene, Environmental Management, Occupational and Construction Safety, and Radiation Protection are ready to assist with risk assessments, chemical safety, physical hazards, hazard-specific training, materials management, and hazardous waste disposal and reuse/recycling. Locally, each department, laboratory, and center has an EHS coordinator, as well as an assigned EHS team, to assist in the implementation of required EHS programs. Each lab/shop also has a designated EHS representative — someone who has local knowledge of your lab/shop and can help you with safety requirements specific to your work area.  

      One of the biggest challenges we face is that due to the decentralized nature of the Institute, no one size fits all when it comes to implementing successful safety practices. We also view this as an opportunity to enhance our safety culture. A strong safety culture is reflected at MIT when all lab and makerspace members are willing to look out for each other, challenge the status quo when necessary, and do the right thing even when no one is looking. In labs/shops with a strong safety culture, faculty and researchers discuss safety topics at group meetings, group members remind each other to wear the appropriate PPE (lab coats, safety glasses, etc.), more experienced team members mentor the newcomers, and riskier operations are reviewed and assessed to make them as safe as possible.  

      Q: Can you describe the new Safe and Sustainable Laboratories (S2L) efforts and the makerspace operational research programs envisioned for the future? 

      A: The MIT EHS Office has a plan for renewing its dedication to sustainability and climate action. We are dedicated to doing our part to promote a research environment that assures the highest level of health and safety but also strives to reduce energy, water, and waste through educating and supporting faculty, students, and researchers. With the goal of integrating sustainability across the lab sector of campus and bridging that with the Institute’s climate action goals, EHS has partnered with the MIT Office of Sustainability, Department of Facilities, vice president for finance, and vice president for campus services and stewardship to relaunch the “green” labs sustainability efforts under a new Safe and Sustainable Labs program.

      Part of that plan is to implement a Sustainable Labs Certification program. The process is designed to be as easy as possible for the lab groups. We are starting with simple actions like promoting the use of equipment timers in certain locations to conserve energy, fume hood/ventilation management, preventative maintenance for ultra-low-temperature freezers, increasing recycling, and helping labs update their central chemical inventory system, which can help forecast MIT’s potential waste streams. 

      EHS has also partnered with Project Manus to build a test-bed lab to study potential health and environmental exposures present in makerspaces as a result of specialized equipment and processes with our new Applied Makerspace Research Initiative.   More

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      in Environment

      MIT collaborates with Biogen on three-year, $7 million initiative to address climate, health, and equity

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      MIT and Biogen have announced that they will collaborate with the goal to accelerate the science and action on climate change to improve human health. This collaboration is supported by a three-year, $7 million commitment from the company and the Biogen Foundation. The biotechnology company, headquartered in Cambridge, Massachusetts’ Kendall Square, discovers and develops therapies for people living with serious neurological diseases.

      “We have long believed it is imperative for Biogen to make the fight against climate change central to our long-term corporate responsibility commitments. Through this collaboration with MIT, we aim to identify and share innovative climate solutions that will deliver co-benefits for both health and equity,” says Michel Vounatsos, CEO of Biogen. “We are also proud to support the MIT Museum, which promises to make world-class science and education accessible to all, and honor Biogen co-founder Phillip A. Sharp with a dedication inside the museum that recognizes his contributions to its development.”

      Biogen and the Biogen Foundation are supporting research and programs across a range of areas at MIT.

      Advancing climate, health, and equity

      The first such effort involves new work within the MIT Joint Program on the Science and Policy of Global Change to establish a state-of-the-art integrated model of climate and health aimed at identifying targets that deliver climate and health co-benefits.

      “Evidence suggests that not all climate-related actions deliver equal health benefits, yet policymakers, planners, and stakeholders traditionally lack the tools to consider how decisions in one arena impact the other,” says C. Adam Schlosser, deputy director of the MIT Joint Program. “Biogen’s collaboration with the MIT Joint Program — and its support of a new distinguished Biogen Fellow who will develop the new climate/health model — will accelerate our efforts to provide decision-makers with these tools.”

      Biogen is also supporting the MIT Technology and Policy Program’s Research to Policy Engagement Initiative to infuse human health as a key new consideration in decision-making on the best pathways forward to address the global climate crisis, and bridge the knowledge-to-action gap by connecting policymakers, researchers, and diverse stakeholders. As part of this work, Biogen is underwriting a distinguished Biogen Fellow to advance new research on climate, health, and equity.

      “Our work with Biogen has allowed us to make progress on key questions that matter to human health and well-being under climate change,” says Noelle Eckley Selin, who directs the MIT Technology and Policy Program and is a professor in the MIT Institute for Data, Systems, and Society and the Department of Earth, Atmospheric and Planetary Sciences. “Further, their support of the Research to Policy Engagement Initiative helps all of our research become more effective in making change.”

      In addition, Biogen has joined 13 other companies in the MIT Climate and Sustainability Consortium (MCSC), which is supporting faculty and student research and developing impact pathways that present a range of actionable steps that companies can take — within and across industries — to advance progress toward climate targets.

      “Biogen joining the MIT Climate and Sustainability Consortium represents our commitment to working with member companies across a diverse range of industries, an approach that aims to drive changes swift and broad enough to match the scale of the climate challenge,” says Jeremy Gregory, executive director of the MCSC. “We are excited to welcome a member from the biotechnology space and look forward to harnessing Biogen’s perspectives as we continue to collaborate and work together with the MIT community in exciting and meaningful ways.”

      Making world-class science and education available to MIT Museum visitors

      Support from Biogen will honor Nobel laureate, MIT Institute professor, and Biogen co-founder Phillip A. Sharp with a named space inside the new Kendall Square location of the MIT Museum, set to open in spring 2022. Biogen also is supporting one of the museum’s opening exhibitions, “Essential MIT,” with a section focused on solving real-world problems such as climate change. It is also providing programmatic support for the museum’s Life Sciences Maker Engagement Program.

      “Phil has provided fantastic support to the MIT Museum for more than a decade as an advisory board member and now as board chair, and he has been deeply involved in plans for the new museum at Kendall Square,” says John Durant, the Mark R. Epstein (Class of 1963) Director of the museum. “Seeing his name on the wall will be a constant reminder of his key role in this development, as well as a mark of our gratitude.”

      Inspiring and empowering the next generation of scientists

      Biogen funding is also being directed to engage the next generation of scientists through support for the Biogen-MIT Biotech in Action: Virtual Lab, a program designed to foster a love of science among diverse and under-served student populations.

      Biogen’s support is part of its Healthy Climate, Healthy Lives initiative, a $250 million, 20-year commitment to eliminate fossil fuels across its operations and collaborate with renowned institutions to advance the science of climate and health and support under-served communities. Additional support is provided by the Biogen Foundation to further its long-standing focus on providing students with equitable access to outstanding science education. More

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      in Environment

      Study: Global cancer risk from burning organic matter comes from unregulated chemicals

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      Whenever organic matter is burned, such as in a wildfire, a power plant, a car’s exhaust, or in daily cooking, the combustion releases polycyclic aromatic hydrocarbons (PAHs) — a class of pollutants that is known to cause lung cancer.

      There are more than 100 known types of PAH compounds emitted daily into the atmosphere. Regulators, however, have historically relied on measurements of a single compound, benzo(a)pyrene, to gauge a community’s risk of developing cancer from PAH exposure. Now MIT scientists have found that benzo(a)pyrene may be a poor indicator of this type of cancer risk.

      In a modeling study appearing today in the journal GeoHealth, the team reports that benzo(a)pyrene plays a small part — about 11 percent — in the global risk of developing PAH-associated cancer. Instead, 89 percent of that cancer risk comes from other PAH compounds, many of which are not directly regulated.

      Interestingly, about 17 percent of PAH-associated cancer risk comes from “degradation products” — chemicals that are formed when emitted PAHs react in the atmosphere. Many of these degradation products can in fact be more toxic than the emitted PAH from which they formed.

      The team hopes the results will encourage scientists and regulators to look beyond benzo(a)pyrene, to consider a broader class of PAHs when assessing a community’s cancer risk.

      “Most of the regulatory science and standards for PAHs are based on benzo(a)pyrene levels. But that is a big blind spot that could lead you down a very wrong path in terms of assessing whether cancer risk is improving or not, and whether it’s relatively worse in one place than another,” says study author Noelle Selin, a professor in MIT’s Institute for Data, Systems and Society, and the Department of Earth, Atmospheric and Planetary Sciences.

      Selin’s MIT co-authors include Jesse Kroll, Amy Hrdina, Ishwar Kohale, Forest White, and Bevin Engelward, and Jamie Kelly (who is now at University College London). Peter Ivatt and Mathew Evans at the University of York are also co-authors.

      Chemical pixels

      Benzo(a)pyrene has historically been the poster chemical for PAH exposure. The compound’s indicator status is largely based on early toxicology studies. But recent research suggests the chemical may not be the PAH representative that regulators have long relied upon.   

      “There has been a bit of evidence suggesting benzo(a)pyrene may not be very important, but this was from just a few field studies,” says Kelly, a former postdoc in Selin’s group and the study’s lead author.

      Kelly and his colleagues instead took a systematic approach to evaluate benzo(a)pyrene’s suitability as a PAH indicator. The team began by using GEOS-Chem, a global, three-dimensional chemical transport model that breaks the world into individual grid boxes and simulates within each box the reactions and concentrations of chemicals in the atmosphere.

      They extended this model to include chemical descriptions of how various PAH compounds, including benzo(a)pyrene, would react in the atmosphere. The team then plugged in recent data from emissions inventories and meteorological observations, and ran the model forward to simulate the concentrations of various PAH chemicals around the world over time.

      Risky reactions

      In their simulations, the researchers started with 16 relatively well-studied PAH chemicals, including benzo(a)pyrene, and traced the concentrations of these chemicals, plus the concentration of their degradation products over two generations, or chemical transformations. In total, the team evaluated 48 PAH species.

      They then compared these concentrations with actual concentrations of the same chemicals, recorded by monitoring stations around the world. This comparison was close enough to show that the model’s concentration predictions were realistic.

      Then within each model’s grid box, the researchers related the concentration of each PAH chemical to its associated cancer risk; to do this, they had to develop a new method based on previous studies in the literature to avoid double-counting risk from the different chemicals. Finally, they overlaid population density maps to predict the number of cancer cases globally, based on the concentration and toxicity of a specific PAH chemical in each location.

      Dividing the cancer cases by population produced the cancer risk associated with that chemical. In this way, the team calculated the cancer risk for each of the 48 compounds, then determined each chemical’s individual contribution to the total risk.

      This analysis revealed that benzo(a)pyrene had a surprisingly small contribution, of about 11 percent, to the overall risk of developing cancer from PAH exposure globally. Eighty-nine percent of cancer risk came from other chemicals. And 17 percent of this risk arose from degradation products.

      “We see places where you can find concentrations of benzo(a)pyrene are lower, but the risk is higher because of these degradation products,” Selin says. “These products can be orders of magnitude more toxic, so the fact that they’re at tiny concentrations doesn’t mean you can write them off.”

      When the researchers compared calculated PAH-associated cancer risks around the world, they found significant differences depending on whether that risk calculation was based solely on concentrations of benzo(a)pyrene or on a region’s broader mix of PAH compounds.

      “If you use the old method, you would find the lifetime cancer risk is 3.5 times higher in Hong Kong versus southern India, but taking into account the differences in PAH mixtures, you get a difference of 12 times,” Kelly says. “So, there’s a big difference in the relative cancer risk between the two places. And we think it’s important to expand the group of compounds that regulators are thinking about, beyond just a single chemical.”

      The team’s study “provides an excellent contribution to better understanding these ubiquitous pollutants,” says Elisabeth Galarneau, an air quality expert and PhD research scientist in Canada’s Department of the Environment. “It will be interesting to see how these results compare to work being done elsewhere … to pin down which (compounds) need to be tracked and considered for the protection of human and environmental health.”

      This research was conducted in MIT’s Superfund Research Center and is supported in part by the National Institute of Environmental Health Sciences Superfund Basic Research Program, and the National Institutes of Health. More

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      in Environment

      Smarter regulation of global shipping emissions could improve air quality and health outcomes

      by

      Emissions from shipping activities around the world account for nearly 3 percent of total human-caused greenhouse gas emissions, and could increase by up to 50 percent by 2050, making them an important and often overlooked target for global climate mitigation. At the same time, shipping-related emissions of additional pollutants, particularly nitrogen and sulfur oxides, pose a significant threat to global health, as they degrade air quality enough to cause premature deaths.

      The main source of shipping emissions is the combustion of heavy fuel oil in large diesel engines, which disperses pollutants into the air over coastal areas. The nitrogen and sulfur oxides emitted from these engines contribute to the formation of PM2.5, airborne particulates with diameters of up to 2.5 micrometers that are linked to respiratory and cardiovascular diseases. Previous studies have estimated that PM2.5  from shipping emissions contribute to about 60,000 cardiopulmonary and lung cancer deaths each year, and that IMO 2020, an international policy that caps engine fuel sulfur content at 0.5 percent, could reduce PM2.5 concentrations enough to lower annual premature mortality by 34 percent.

      Global shipping emissions arise from both domestic (between ports in the same country) and international (between ports of different countries) shipping activities, and are governed by national and international policies, respectively. Consequently, effective mitigation of the air quality and health impacts of global shipping emissions will require that policymakers quantify the relative contributions of domestic and international shipping activities to these adverse impacts in an integrated global analysis.

      A new study in the journal Environmental Research Letters provides that kind of analysis for the first time. To that end, the study’s co-authors — researchers from MIT and the Hong Kong University of Science and Technology — implement a three-step process. First, they create global shipping emission inventories for domestic and international vessels based on ship activity records of the year 2015 from the Automatic Identification System (AIS). Second, they apply an atmospheric chemistry and transport model to this data to calculate PM2.5 concentrations generated by that year’s domestic and international shipping activities. Finally, they apply a model that estimates mortalities attributable to these pollutant concentrations.

      The researchers find that approximately 94,000 premature deaths were associated with PM2.5 exposure due to maritime shipping in 2015 — 83 percent international and 17 percent domestic. While international shipping accounted for the vast majority of the global health impact, some regions experienced significant health burdens from domestic shipping operations. This is especially true in East Asia: In China, 44 percent of shipping-related premature deaths were attributable to domestic shipping activities.

      “By comparing the health impacts from international and domestic shipping at the global level, our study could help inform decision-makers’ efforts to coordinate shipping emissions policies across multiple scales, and thereby reduce the air quality and health impacts of these emissions more effectively,” says Yiqi Zhang, a researcher at the Hong Kong University of Science and Technology who led the study as a visiting student supported by the MIT Joint Program on the Science and Policy of Global Change.

      In addition to estimating the air-quality and health impacts of domestic and international shipping, the researchers evaluate potential health outcomes under different shipping emissions-control policies that are either currently in effect or likely to be implemented in different regions in the near future.

      They estimate about 30,000 avoided deaths per year under a scenario consistent with IMO 2020, an international regulation limiting the sulfur content in shipping fuel oil to 0.5 percent — a finding that tracks with previous studies. Further strengthening regulations on sulfur content would yield only slight improvement; limiting sulfur content to 0.1 percent reduces annual shipping-attributable PM2.5-related premature deaths by an additional 5,000. In contrast, regulating nitrogen oxides instead, involving a Tier III NOx Standard would produce far greater benefits than a 0.1-percent sulfur cap, with 33,000 further avoided deaths.

      “Areas with high proportions of mortalities contributed by domestic shipping could effectively use domestic regulations to implement controls,” says study co-author Noelle Selin, a professor at MIT’s Institute for Data, Systems and Society and Department of Earth, Atmospheric and Planetary Sciences, and a faculty affiliate of the MIT Joint Program. “For other regions where much damage comes from international vessels, further international cooperation is required to mitigate impacts.” More